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Tài liệu Báo cáo khoa học: The distinct nucleotide binding states of the transporter associated with antigen processing (TAP) are regulated by the nonhomologous C-terminal tails of TAP1 and TAP2 ppt
... binding of ADP by variant 1V2 does not shift thenucleotide binding behaviour of wild -type TAP2 from ADPto ATP.We compared the transport activity of TAP variant1–2V1 and 2–1V2 with that of wild -type ... [49].Replacement of the C-terminal tail in wild -type NBD1 with that of wild -type NBD2 leads to a chimeric NBD1,which is apparently locked in an ADP binding conforma-tion that blocks peptide translocation of ... transport activity whencompared to the original variant 2–1N2 with identicalC-terminal segments. The transport efficiency of variant2–1C2 was 40–55% of that of wild -type TAP. Thus, thechimeric...
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SPECIAL REPORT: National Survey of Children’s Health Finds Intact Family and Religious Participation Are Associated with Fewer Developmental Problems in School-Age Children pdf
... than half of all children live with both parents. (Nowadays, 70percent of black children nationwide are born outside of marriage, as are 25percent of white children and 48 percent of Hispanic ... thequality of the relationship with their parents.Children who live with both biological parents or two adoptive parents are most likely to have a high-quality relationship with their parents. ... biologicalparents of the child, or two adopted parents; 2) a biological parent and astepparent; 3) the biological mother only; or 4) other parent figures, including thebiological father only, grandparent(s)...
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Reproductive Senescence in a Long-Lived Seabird: Rates of Decline in Late-Life Performance Are Associated with Varying Costs of Early Reproduction pot
... empirical studies are rare. Anal-yses of senescence (both actuarial and reproductive) are problematic because of the inherent problems involved inobtaining large enough samples of the oldest cohorts ... individuals with high early-life reproductiveoutput have reduced breeding success late in life regardless of when in the season they lay, implying that delayed costs of reproduction are associated with ... wasrepeated with and without the effects of period and yearnested within period and also with year as a factor in thefixed model rather than the random model. These alter-native ways of specifying...
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báo cáo hóa học: " Indoors illumination and seasonal changes in mood and behavior are associated with the health-related quality of life" pdf
... associations of HRQoL with exposure to illumination and with seasonal changes inmood and behavior. To be specific, we aimed at elucida-tion of associations, if any, of the 15D Health-RelatedQuality of ... CentralPage 1 of 8(page number not for citation purposes)Health and Quality of Life OutcomesOpen AccessResearchIndoors illumination and seasonal changes in mood and behavior are associated with ... illumination indoors (P = 0.0035) were associated with more severe mental ill-being.Conclusion: The routinely emerging seasonal changes in mood and behavior are associated with the HRQoL and mental well-being....
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Báo cáo sinh học: " Typing of human rotaviruses: Nucleotide mismatches between the VP7 gene and primer are associated with genotyping failure" pdf
... 3' end of the primer binding site. ArchVirol 1997, 142:1881-1887.Effect of untypeable strains on G typing of Bangladeshi rotavirus strains isolated in 2002 (n = 433)Figure 1Effect of untypeable ... propor-tion of the specimens were untypeable. Nucleotidesequences of VP7 genes were performed to investigate thereason why they were untypeable with the routine primerset. The untypeable specimens ... (Fig. 1). Type G1 now accounted for44.8% of the isolates and became the most prevalent gen-otype, and the number of untypeable strains was reducedfrom 36.9 to 2.1 %. The other common G types were...
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báo cáo hóa học: " Low ficolin-3 levels in early follow-up serum samples are associated with the severity and unfavorable outcome of acute ischemic stroke" pptx
... concentration with the outcome of the disease in 65 patients with ischemic stroke Panel A: Distribution of the patients with different outcome of the disease among patients with low (<6), ... 2005 [26]; those with a NIH scale of <16 with relatively good expected outcome and those with NIH scale of >16 with poor expected outcome, and the ficolin-3 levels were compared accordingly. ... concentration of ficolin-1 is much lower [25]. Similar to MBL, the ficolins are associated with a set of three serine proteases, termed MBL -associated serine proteases (MASPs), enabling activation of...
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Báo cáo hóa học: " Respiratory syncytial virus (RSV) attachment and nonstructural proteins modify the type I interferon response associated with suppressor of cytokine signaling (SOCS) proteins and IFN-stimulated gene-15 (ISG15)" potx
... understand aspects of theimmunobiology of infection. Mouse lung epithelial(MLE)-15 cells offer a good option to emulate the mousemodel of RSV infection as these cells are a type II pneumo-cyte ... finding is in keeping with the findings of NS1/NS2 antagonism of type I IFNs [4,46,47] and sug-gests the possibility that type I IFN antagonism is linkedto NS1/NS2 induction of SOCS1 and subsequent ... following infection with WT, ΔG, or ΔNS1/2 virus at a multiplicity of infection (MOI) of 1 for 24 h (A) or 48 h (B) as indicated. Data are shown as means ± standard errors (SE) of the means. Virology...
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Báo cáo hóa học: " Nucleotide mismatches between the VP7 gene and the primer are associated with genotyping failure of a specific lineage from G1 rotavirus strains" potx
... Neighbor-joining or parsimony meth-ods with Kimura 2-parameter as a model of nucleotidesubstitution with the MEGA 3.1 [26] and Phylip v3.65softwares. The statistical significance of the tree was pre-formed ... grouped within one of the four lineages pre-viously reported by Jin et al [5] (Fig. 1). The typeable anduntypeable G1 strains reported by Rahman et al [19],grouped within the lineage I with a ... four (61.2 %) out of 121 G1 strains from lineage I showed the four specificmismatches at the 5' end of the 9T1-1 primer. This was associated with the failure of genotyping of G1 strainsfrom...
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báo cáo hóa học:" Typing of human rotaviruses: Nucleotide mismatches between the VP7 gene and primer are associated with genotyping failure" pptx
... 3' end of the primer binding site. ArchVirol 1997, 142:1881-1887.Effect of untypeable strains on G typing of Bangladeshi rotavirus strains isolated in 2002 (n = 433)Figure 1Effect of untypeable ... Gowda K, Reddy BS: Sequence analysis of VP4 and VP7genes of nontypeable strains identifies a new pair of outercapsid proteins representing novel P and G genotypes inbovine rotaviruses. Virology ... rotaviruses into at least 15 G-geno-types. Among them, G1, G2, G3, G4 and G9 are the mostcommon G-types in humans [5,15,16,19,21,23]. Theimportance of type- specific immunological protectionagainst...
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báo cáo hóa học:" Decreased levels of serum glutathione peroxidase 3 are associated with papillary serous ovarian cancer and disease progression" pot
... 4:18http://www.ovarianresearch.com/content/4/1/18Page 3 of 8 Figure 1 Comparison of GPX3 levels of healthy female controls vs. women with serous ovarian cancer for women of all ages: Figure1A shows a group-wise comparison of GPX3 in healthy ... al. Journal of Ovarian Research 2011, 4:18http://www.ovarianresearch.com/content/4/1/18Page 8 of 8 the serum of women with papillary serous ovariancancer.Oncogenesis is associated with an increase ... women with late stage disease (p = 5ì10-4) and recurrence of their cancer (p = 1 ì 10-2)hadsignificantly lower levels of GPX3 than women with earlystage disease. T hese results are summarized...
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Báo cáo y học: "Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers" doc
... association of endostatin with giant capillariesand microhemorrhages and of the higher levels of endo-statin in patients with avascular areas argue for a role of endostatin in the pathogenesis of microvascular ... which are associated with a morerapid and severe disease course [38]. These results are consistent with findings from Kikuchi et al., who showed acorrelation of VEGF with the frequency of lung ... systemic sclerosis:increased levels of vascular endothelial growth factor are afeature of the earliest disease stages and are associated with the absence of fingertip ulcersOliver Distler1,...
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Báo cáo y học: "Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity" ppt
... 5Research articleReduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunityJoan Wither1, Yong-chun Cai2, Sooyeol Lim3, ... disease were independentlyand cumulatively associated with a reduced proportion of NKTcells. Nevertheless, the proportion of NKT cells was reducedas compared with normal control individuals, even ... relatives of lupus patients compared with control individuals. Although the reduced proportion of NKT cells was not as pronounced as that seen in the probands(P = 0.0009 for relatives as compared with...
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Báo cáo y học: "erum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and vascular damage in rheumatoid arthritis" doc
... S100A9 levels were associated with body mass index (BMI), and with serum levels of S100A8 andS100A12. S100A8 levels were associated with serum levels of S100A9, presence of anti-citrullinated ... (RF). S100A12 levels were associated with presence of ACPA, history of diabetes, andserum S100A9 levels. sRAGE levels were negatively associated with serum levels of C-reactive protein (CRP) ... http://arthritis-research.com/content/11/2/R39Page 1 of 11(page number not for citation purposes)Vol 11 No 2Research articleSerum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with...
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Sodium valproate-induced congenital cardiac abnormalities in mice are associated with the inhibition of histone deacetylase ppsx
... administration of NaVP in pregnant mice can result in various cardiac abnormalities in fetal hearts, which is associated with an inhibition of histone deacetylase without altering the transcription of ... that administration of NaVP in pregnantmice can result in various cardiac abnormalities in fetalhearts, which is likely associated with an inhibition of his-tone deacetylase without altering ... cardiac abnormalities in fetalhearts, which is likely associated with an inhibition of his-tone deacetylase without altering the transcription of thisenzyme.MethodsAnimalsThe C57/B6 mice used...
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báo cáo khoa học: " Polymorphisms in the SULF1 gene are associated with early age of onset and survival of ovarian cancer" ppsx
... with age of onset of ovarian cancer. Forexample, the rs2623047 G>A showed an association with age of disease onset (Table 3); the patients with the AAgenotype had a mean age of onset of 65.0 ... Open AccessPolymorphisms in the SULF1 gene are associated with early age of onset and survival of ovarian cancerChan H Han1, Yu-Jing Huang1, Karen H Lu2, Zhensheng Liu1, Gordon B Mills3, ... significantly associated with an early age of onset of ovarian cancer inthe G allele dose-response manner (P = 0.027; Ptrend= 0.007) and that rs2623047 GG/GA genotypes were associated with longer progression-free...
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