... ofthe consistency ofthe policy: Are the means employed by the policy consistent with the set objectives? ã Evaluation ofthe impact ofthe policy: Whatisthe economic and social impact of ... discussed at the Liaison Officers Meeting on 4-5 October. In conclusion, the Contact Committee of Heads ofthe Supreme Audit Institutions ofthe Member States ofthe European Union and the ... recommendations. The report may entail the analysis ofthe SAI work inthe previous year, including information on audit work, information on training activity; a summary of issues arising from quality...
... trains a broad spectrum ofthe planning and engineering community inthe effective implementation of WSUD. The Partnership is proactively securing the implementation oftheState Planning Policy ... watersheds, what isthe geographical scope ofthe factors contributing to or influencing these issues? (Mollinga et al 2007). The alternative option of a situational analysis of an individual ... economy. It is expected that the activity ofthe sector will increase in 2010, however this progression will be constrained by the strength ofthe Australian dollar, the increase ofthe price of air...
... sub-unit ofthe G protein and not inthe other case.Although there is discussion inthe literature concern-ing the possibilities of photoconversion of YFP into aCFP-like species during acceptor ... traf-ficking properties. The binding experiments alsopointed to a decrease inthe density ofthe D2R vari-ants inthe cellular membrane; the number of D2receptor binding sites decreased with the ... localization of these proteins inthe cell rather thanfrom the possible roleofthe D2R basic domain inthe mechanism of D1–D2receptor heterodimerization. However, we find that the acidicepitope...
... be interpreted bythis hypothesis. The hypothesis will also be extendedto the analysis ofthe possible roleof C-terminalmulti-helix domain in this process.Investigation of bacterial PAL structuresAs ... biosynthesis ofthe photoactive yellow proteinchromophore of these bacteria. The two recently discovered aminomutases, the phe-nylalanine 2,3-aminomutase (PAM) involved in taxolbiosynthesis in ... study the behavior ofthe Tyr110-loop in PAL in moredetail.Results and discussionModeling the active conformation of the essential Tyr110-loop of parsley PALBecause ofthe uncertainty of the...
... theroleof HSP70 inthe inhi-bition ofthe release of Smac and apoptosis. The roleofthe ATP-binding domain of HSP70 in the prevention ofthe release of Smac andapoptosis after exposure to ... supporting the roleof HSP70 inthe protection of C2C12 cells from H2O2-induced andSmac-promoted apoptosis by preventing the release of Smac from mito-chondria, thereby inhibiting activation of ... eliminating inhibition of caspases by inhibitor of apoptosis protein (IAP) and is known to be a new andimportant regulator of apoptosis in a variety of cancercells. The evidence obtained in...
... cancer risk factors, otherthan age, was available for inclusion in their models [19].To obtain more insight into theroleofthe fat breast tis-sue, we investigated the independent effects ofthe ... studies have investigated theroleof the breast fat tissue with different results. Stone et al. investi-gated theroleofthe non-dense area in a group of women in the United Kingdom comparable ... reader;onetodistinguishthebreastareafromthebackgroundand a second to distinguish the dense from the non-densearea. Furthermore, the pectoralis muscle was masked out. The non-dense area was obtained...
... downward bias inthe variability ofthe real rate depending on the level ofthe nominal equilibrium rate of interest. The downward bias inthe variability of the real rate accounts for the reduced ... above, the distortion of output and in ation distributions is driven by adistortion ofthe real interest rate. The left-hand panels of Figure 5 report the upward bias in the mean real rate and the ... panels of Figure 5. Thisreduction inthe stabilizing function ofthe real exchange rate is consistent with what weobserved inthe recession and deflation scenario discussed inthe preceding subsection....
... for the Wilson pro-tein, the N-terminus interacts with another domain of Ccc2 (the catalytic loop for example) and this interac-tion inhibits the ATPase activity. Truncation of the N-terminus ... to investigate the role of various amino acids in these proteins [25–28].Although these studies provide useful informationabout the functionality ofthe ATPase, they are allinterpreted independently ... Huster D & Lutsenko S (2003) The distinct roles of the N-terminal copper-binding sites in regulation of cata-lytic activity ofthe Wilson’s disease protein. J BiolChem 278, 32212–32218.40...
... scared by the interminable singing, shouting, bell-jingling, horn-blowing, and other such merry noises ofthe moving caravan, could be seen disappearing inthe distance. Leaving the park, ... to the boisterous. Expert slavehunters, they mostly clothe themselves by the sale of their victims on the coast, though they do business by the sale of goats and grain as well. Nowhere inthe ... consideration isthe power held by the magician (Mganga), who rules the minds ofthe kings as did the old popes of Europe. They, indeed, are a curse to the traveller; for if it suits their inclinations...