... management of incidental findings in research studies has not been raised in musculoskeletal imaging It is important given the increasing use of MRI inthe investigation of OA by researchers trained ... more precise prevalence estimate However, this isthe first study in this area Our findings raise issues for the planning of studies and ethical issues related to the obligation ofthe physician-researcher ... radiologist or other suitably trained specialist review all the images or just the baseline images in a longitudinal study This will also add to the cost ofthe research study Despite the increasing...
... distribution and management of missing data (n = 10) Only one-half ofthe authors contextualized findings within existing literature The weakest section of reporting across studies was planning ofthe interventions, ... established, the barriers and facilitators to establishing and implementing teams and team initiatives, as well as the strength ofthe evidence about the impact of team initiatives Before embarking ... considered in interpreting the results of this review First, the search was broad and included studies of quality and safety team initiatives without operational definitions of quality and safety This...
... result in poor reproducibility and thus variance in prevalence of nonresponders These may include the dose ofthe agonist (5-20 uM), the nature ofthe anticoagulant (citrate or hirudin/PPACK) andthe ... coupled with the low prevalence of events, implies that testing of platelet ADP antagonist responsiveness is unlikely to provide useful information to guide clinical decision-making in most individual ... (1) “ the tests are crude substitutes for the .interactions …… in vivo” (2) “ failed to satisfy… the minimal criteria to establish a causal relationship…between the results ofthe test and ……...
... monetization," the old man said "Maintaining a blog is a lot of work, andthe blogger has the right to earn some income The ads aren't too distracting, and they actually complement the blog by providing offers ... Whatisthe Sound of One Hand Clapping? If you're into Zen and you're into blogging, read and share this ebook If you're into Zen but you're not into blogging, share this ebook If ... length," the old man said "This blogger is mainly reporting the news in her industry She's gotten good at quickly saying what needs to be said, and pointing her readers to where they can get more information."...
... paradigm where a predefined level of demand is managed internally andthe remainder augmented with cloud services The apothegm is ‘Own the base and rent the peak’ Conclusion The customer’s overall ... assessment of value The assessment of value of cloud services can only include a comparison against other cloud providers The comparison of cost between traditional IT investment and cloud services ... Sourcing's Three Fates The IT Outsourcing RFP COW is too FAT AMS - The next stage inthe evolution of IT Outsourcing Outsourcing’s Two Evils Apply CREAMS to your IT Outsourcing pain Sourcing’s...
... measured by smoking, drinking, exercising andthe body mass index – contribute to explaining the gradient We find that the effects of education on smoking, drinking, exercising and eating a proper diet ... one ofthe indicator is ordinal andthe others are continuous We list below the synthetic indicators, the observed variables used for each indicator andthe interpretation we propose, based on the ... three binary indicators: whether the mother died early, whether the father died early and whether the mother andthe father where present when the individual was aged 10 The extracted principal...
... The impact of microfinance on the incomes ofthe poor b The impact of microfinance on wider poverty/ wealth ofthe poor c impact of microfinance on other non-financial The outcomes for the ... ofthe failure of micro-credit and not its success There isthe potential for clients to remain in a cycle of borrowing or saving, investing inthe future, increasing income, repaying loans and ... reviewed and published at the start ofthe project During the course ofthe project we drew on the expertise of potential users ofthe review, including researchers, policy advisers and microfinance...
... fields; raising the profile of aesthetics andthe philosophy of art within the profession of philosophy; collaborating with academic societies of aesthetics in other countries; fostering common interests ... article (this issue), the scientific study of aesthetics can be traced back to the beginning of experimental psychology andthe work of Gustav Theodor Fechner inthe second half ofthe nineteenth ... Aesthetics is soliciting applications and nominations for the position of editor ofThe Journal of Aesthetics and Art Criticism, the official journal ofthe Society, to begin February 2013 (The second...
... lefthand side of r corresponds to the root label of t andthe righthand side of r corresponds to the frontier labels of t Indices link the rules to the original subtrees so as to maintain the ... could be the case that DOP's gain in parse accuracy with increasing subtree depth is due to the model becoming sensitive to the influence of lexical heads higher inthe tree, and that this gain could ... accuracy.) 4.4 The impact of structural context Instead of investigating the impact of lexical context, we may also be interested in studying the importance of structural context We may raise the question...
... because the chronology ofthe opinions andthe judgments is so staggered, to examine and contrast first the approach ofthe Advocates General in each case chronologically and then the judgments inthe ... Houdini-like in its contortions in its findings on whether or not the Keck conditions for removing measures from the scope ofthe Dassonville basic principle are satisfied.10 The issue of whether ... is therefore, in my view, preferable to examine measures of that kind inthe light ofthe Treaty rules rather than to remove them from the scope ofthe Treaty.79 Inthe light of these three reasons,...
... takes time, and that the grabbing at features andthe blending inofthe new andthe traditional may be on the road to a healthier Hegelian synthesis type of thing.” On the other hand, she added, ... principal operating agency of both the National Academy of Sciences andthe National Academy of Engineering in providing services to the government, the public, andthe scientific and engineering communities ... creating their own standards Another participant pointed out that the NSES have “raised the debate” regarding the issue of science standards One attendee cited the increased emphasis on inquiry in...
... analysis [7-10,15-17], but there is little information about the corresponding serological activity of HMGB1 andthe progression of GC Although the measurement of HMGB1 activity in tissues is clinically ... CEA for the diagnosis of high-risk lesions and EGC The CEA and HMGB1 cut-off points that gave the best sensitivity and specificity for the diagnosis of high-risk lesions (IM and adenoma) and cancer ... could be clinically useful; however, the utility ofthe evaluation of HMGB1 over-expression in tissue is somewhat limited because ofthe relatively higher-risk, invasiveness and high cost ofthe procedures...
... practice The interpretation of HRQoL scores raises many issues [1–7] The scales and instruments used may be unfamiliar to many clinicians and patients, who may be uncertain ofthe meaning ofthe scale ... on what a clinically important difference is for the SF-36 scales They conclude that the MCID for the SF-36 is "typically inthe range of 3–5 points", although they also recommend caution in interpreting ... SF-6D is a continuous measure of effect we used meta-analytic methods to estimate the weighted grand mean ofthe MID and to test the hypothesis of homogeneity of MID across the nine studies If there...
... the final product isthe result of ‘wetting’ by the liquid present upon sintering The extent of this ‘wetting’ during liquid-phase sintering, being dependent upon molten binder metal dissolving ... inserts consist of: • ‘Pure’ ceramic – this isthe traditional tooling insert material, consisting of aluminium oxide The alumina is white in colour andis produced by cold pressing powder inthe desired ... rationalisation (Fig 1) consists of looking at the results ofthe previous tooling survey and significantly reducing the number of tooling suppliers for particular types of tools and inserts This initial...
... Part 2: Whatisthe importance of good human resources management? Recruitment and training Human resource management help looking good staff actively involved inthe success ofthe company and help ... help recruit the right people for the company, human capital is guaranteed, saving time and recruitment costs 1 Recruitment and training Staff training is an integral part ofthe overall ... strategy ofthe business Staff are not trained or not trained fit isthe main cause leading to the current state enterprises are not competitive enough inthe market 2 Conflict resolution Resolving...
... role inthe aetiology ofthe disease itself [44] Disease stage and phase of therapy In PSV, and especially in SVV, the therapeutic approach usually consists of an induction of remission and a maintenance ... of targeting this problem: recognising and minimising risk factors, implementing prophylaxis where appropriate and ensuring early diagnosis and targeted therapy if infections occur Although there ... For induction, more aggressive regimens, including Cyc and higher GC doses, are utilised Furthermore, in SVV the selection of drugs depends on the stage ofthe disease: inthe localised and early...
... andthe linea alba, andthe VAT was defined as the distance between the anterior wall ofthe aorta andthe internal face ofthe recto-abdominal muscle perpendicular to the aorta When the aortic ... the moment of study Discussing possible mechanisms and explanations for our findings, we can argue that IR presence isthe most important factor in determining the fat deposition in organs (in ... absolute risk because SAAT volume is greater than VAT [19]; jjjj) in adults, visceral fat is directly associated with liver inflammation and fibrosis independently of insulin resistance and HS and...
... considered This interesting approach was successful inthe experimental setting of acute lung injury and needs to be verified inclinical indications other than lung transplantation Competing interests ... transplantation Inthe cases of graft failure, brain death and infection ofthe donor lung, reduced surfactant function is aggravated by preservation ofthe graft, ischaemia and reperfusion Therefore, ... substitution of surfactant may bridge the patient to recovery ofthe graft The combination of iNO and surfactant proved to be successful in experimental severe reperfusion injury [15], strengthening Della...
... degree of ω-oxidation occurs, potentially increasing the risk for toxicity Less than 3% of VPA is excreted unchanged inthe urine [10,14,15], much of which isinthe form of valproylcarnitine [27,28] ... valproylCoA in brain tissue, suggesting that the effects of VPA inthe CNS are independent ofthe formation of this metabolite [80] Development of cerebral oedema is not clearly correlated with the dose ... [38] Administration of exogenous carnitine is thought to decrease ammonia levels by binding to VPA, thereby enhancing the β-oxidation process and production of acetyl-CoA, and relieving the inhibition...