... alka-
Editorial
What do biomarkers tellusabout the pathogenesis of
ankylosing spondylitis?
Walter P Maksymowych
Department of Medicine, University of Alberta, Edmonton, Alberta T6G 2S2 Canada
Corresponding ... clearly not feasible in the spine and limited
analysis has focused on associations with MRI scores for
spinal inflammation. Significant correlations have been
reported with interleukin-6 and vasoactive ... major priority for investigation in
AS because of the generally slow rate of progression of
radiographic change [2]. Such a biomarker could then be
used to enrich for rapid progressors in trials...
... isotopes, that tell you
this), just to get its block knocked off again by whatever nasty boxer
the P-T extinction mechanism (mechanisms?) really was. Now this
was a surprise, and one that was hard ... the manuscript by Becker et al. was sent to col-
leagues for prepublication scrutiny. Not because the impacter size was
not a
ppropriate—on the contrary, the size was the same as that caus-
ing ... just then becoming accustomed to impact
as a general cause of mass extinction, this discovery came as a mild
shock—mild, because it was largely overlooked by those searching for
impact-caused...
... separately (figures 3A
to 3D). The Devinas population was tested and was found to
be of Corsican origin by using the three microsatellites
pooled or by using either the FRPP91 or the ITPH4516.
A more ... were used.
2.2. Genetic diversity statistical analysis
Principal component analysis (PCA) was used to retrieve infor-
mation about the clustering pattern of the analysed populations.
PCA was performed ... value,
while significantly different from 0.
Differentiation was highly significant for all pairs of
groups (all cases P < 0.0000).
3.5. Use of nuclear microsatellites to distinguish
Corsican from Aquitaine...
... (76.3%) than those who were GB-
trained (64.9%), whereas they were less likely to work in
hospital pharmacy (16.9% versus 21.1%). This finding
was the reverse for pharmacists who had joined the ... evidence about
active recruitment of pharmacists outside Great Britain,
there is no published research evidence that has examined
this. What is documented is that about 8% of pharmacists
who live ... 2007 were also analysed by identifying those
pharmacists who joined between August 2006 and August
2007 ("joiners"), and those who left in the same period
("leavers").
Results
Registrations...
... on
the graph, was at the very lowest end of the forecasts. Energy use turned out to be
lower than was considered plausible by almost every forecaster. The Lovins sce-
nario, discussed below (which ... the Decision at Hand
Thousands of person-hours are wasted each year because people asking for fore-
casts have no clear idea of what decision they are trying to influence or who will
make that decision. ... to
be robust, and end-use analysis when it appears to provide more insight. This
kind of approach is being used increasingly in both industry and government, and
especially by the utility industry...
... management at the Internet services who pro-
vided us data and answered our questions about the data.
This work was only possible because of their help. We
regret that we cannot thank these services ... caused about 10% of
failures, software about 20%, and system management a
bit over 50% [15].
Our study is similar in spirit to two studies of net-
work failure causes: Mahajan examined the causes ... community about why large-scale systems fail,
and what techniques could prevent failures. In an
attempt to answer the question “Why do Internet ser-
vices fail, and whatcan be done about it?”...
... access
of a whole linguistic structure, i.e. we recall the
familiar proverb ‘You can lead a horse to water
but you cannot make it drink’, and the deviation
from the recognizable structure causes the ... dis-
course. This is discussed in more detail later.
2.1 Lexicons for Discourse modeling
Pustejovsky’s Generative Lexicon (GL) model
(Pustejovksy, 1995) outlines an ambitious attempt
to formulate ... (4) results from the polyse-
mous use of the word bar. The first sentence leads
us to believe that bar is a place where one drinks,
but the second sentence forces us to revise our in-
terpretation...
... because the proteins do
not fold appropriately.
The more commonly used killed
vaccines are made from viruses in-
activated in formalin or β-propio-
lactone and used either as a whole
virus or ... detected by
antibodies against the original virus
and cause annual, or biennial,
‘seasonal’ influenza outbreaks. Such a
virus can spread across the USA
within a single month.
New HA and NA types ... H5N1 threat took
even longer, because the H5N1 viruses
were so virulent that they killed chick
embryos before much virus was made,
and new recombinant vaccine viruses
had to be made by inserting...
... scale wasabout 4
◦
C within the
range between 15 to 22
◦
C. The camera was mounted on a tripod
and focused on the stem of sample tree, so that the whole area of the
smooth stem surface was visible ... stem and the opened xylem surface was smoothed by a
sharp knife. The IR-camera was focused on this accordingly prepared
stem surface. The radial HFD-sensor was installed from the opposite
(northern) ... one particular day. It was August 11th, 1999,
when a more than 90% solar eclipse was shadowing the lime
tree at 1 pm. This eclipse is seen as a clear dip in the con-
tinuous sap flow recording in...