... both thetypesof speech role that they are taking on inthe dialogue and the whole cluster of socially significant relationships in which they are involved?+ The MODE OF DISCOURSE concerns what ... what part the language is playing, what it is thatthe participants are expecting the language to do for them inthat situation, the symbolic organisation ofthe text, the status that it has, ... function inthe context, including the channel (is it spoken or written or some combination ofthe two? ) and also the rhetorical mode, what is being achieved by the text in terms of such categories...
... shops may be the only source of living of then. To conclude I would like to express my opinion which rather possitive. I think that supermarkets are great creatures and the more of them the better. ... " ;two for the pirce of one" are always found there.One the other hand shopping in supermarkets can be annoying beckause there is a big choice which can cause confusion.People often ... buy things they do not actually need. For many of us the major disadvantage of shopping in supermarkets id that it is time consuming and it takes a while to getthere and back.Big stores are...
... positions of cysteineresidues in Hep-JF2 of Japanese flounder arethe sameas those of human hepcidin, while the number and posi-tions of cysteine residues in Hep-JF1 arethe same asthose in type ... from thatof human,mouse and other reported fish hepcidins. In liver, somecells expressed both typesof hepcidins, while othercells expressed only one of them or neither of them(Fig. 6). These ... 5263 The human and mouse hepcidin genes are predomin-antly expressed inthe liver [1,2]. Expression of mam-malian hepcidins is induced by interleukin-1,interleukin-6, LPS and iron overloading...
... identified two subsites on this moleculecomprising Ôresidues inthe protruding domain consisting of the type VI b-turn and the first part of b-strand 3Õ (i.e. the b-hairpin loop and part ofthe adjoining ... obtained by other groupswho also point to the role ofthe connecting loop of the b-hairpin of defensins. A combination of mutationalanalysis [35] and structural analysis ofthe plant defensinRs-AFP1 ... importance ofthe loopsequence bridging thetwo common b-strands of defensins in their biological activity. Our hypothesis is that this protru-ding part ofthe molecule might initiate the molecularprocess...
... showed that there is an accumulation of sumoylatedMyb inthe insoluble fraction ofthe nucleus, indicating that sumoylation stabilizes the association of c-Myb withinsoluble structures inthe ... conjugation and that modification ofthetwo sites are interdependent, and (c) a two- hybrid screening shows thatthe SUMO-1 conjugaseUbc9 is one of a few major Myb-interacting proteinsexpressed in bone ... several subdomains of c-Myb revealed strongestsubdomain interaction with the EVES-domain inthe NRD-region of c-Myb, suggesting that this region might beinvolved inthe UBC9 interaction (results...
... are made by others. The great increase inthe use of the Treasury bill to finance government borrowing [in the First World War] allowed the discount market to survive by making these its main ... inthe 1920s, becamemoribund during the banking difficulties and the excessively low money rates of the 1930s, continued moribund during the era of pegged interest rates ofthe 1940s, andfinally ... Wednesday of April) foreach year. They reject a series obtained via a “smoothing procedure” (presumablyincluding averaging) ofthe original data, because the “statistical properties” ofthe seriesare...
... b of hidingit.Sadly,itiseasytofindmanyexamples ofthe mistakesyoushouldavoidbylookingnofurtherthan the websites ofthe softwarevendorsthemselves.Let'susesome of theseexamplestoexaminedesign that doesn'tworkandlearnwhyitdoesn't.Note: In almosteverycase,I'vechosentouseactualexamplesfromvendorwebsitestoillustratedashboarddesignmistakes. In doingso,Iamnotsaying thatthe software that produced the exampleisbadI'mnotcommentingon the quality ofthe softwareonewayoranother. What Iamsayingis thatthe designpracticeisbad. ... suchas the amount of time that passedbetweenevents in aprocess(forexample,byassociatinganumberwith the line that links the eventsorbyhaving the length ofthe lineitselfencode the duration)or the sizes of businessentities(perhapsexpressed in revenuesornumber of employees).www.it-ebooks.info ... odorbaditis.Theycouldeasilyhavedonethisbylabeling the quantitativescalesandvisuallyencodingsectionsalong the scalesasgoodorbad,ratherthanjustencoding the arrows in thismanner.Hadthisbeendone,wewouldbeabletoseeataglancehowgoodorbadameasureisbyhowfar the arrowpointsinto the goodorbadranges. The gauge that appears in Figure3‐5doesabetterjob of incorporatingcontext inthe form of meaningfulcomparisons.Here, the potential ofthe graphical...
... b of hidingit.Sadly,itiseasytofindmanyexamples ofthe mistakesyoushouldavoidbylookingnofurtherthan the websites ofthe softwarevendorsthemselves.Let'susesome of theseexamplestoexaminedesign that doesn'tworkandlearnwhyitdoesn't.Note: In almosteverycase,I'vechosentouseactualexamplesfromvendorwebsitestoillustratedashboarddesignmistakes. In doingso,Iamnotsaying thatthe software that produced the exampleisbadI'mnotcommentingon the quality ofthe softwareonewayoranother. What Iamsayingis thatthe designpracticeisbad. ... are implementingdashboards."2Unfortunately, the authornevertellsus what dashboards are. Heteasesuswithhints,stating that dashboardsandscorecards are BItools that "havefoundanewhome inthe cubicles,"havingmovedfromwheretheyonceresided(exclusively in executivesuites)under the nameExecutiveInformationSystems.Hegivesexamples of howdashboards are beingusedandspeaks of theirbenefits,butleavesittoustopiecetogetherasense ofwhat they are. The closesthecomestoadefinitioniswhenhequotesJohnHagerty of AMR Research, Inc.:"Dashboardsandscorecards are aboutmeasuring."Whileconductinganextensiveliteraturereview in 2003 in search of agoodworkingdefinition,IvisitedDataWarehousingOnline.comandclickedon the linkto"ExecutiveDashboard"articles. In response,Ireceived the same18webpages of links that IfoundwhenIseparatelyclickedonlinksfor"BalancedScorecard,"" ;Data QualityandIntegration,"and" ;Data Mining."Either the linksweren'tworkingproperly,orthiswebportalfor thedata warehousingindustryat the timebelieved that thesetermsallmeant the samething.3Ifinallydecidedtobegin the task of devisingaworkingdefinition of myownbyexaminingeveryexample of adashboardIcouldfindon the Web, in search of theircommoncharacteristics.Youmightfinditinterestingtotakeasimilar ... are implementingdashboards."2Unfortunately, the authornevertellsus what dashboards are. Heteasesuswithhints,stating that dashboardsandscorecards are BItools that "havefoundanewhome inthe cubicles,"havingmovedfromwheretheyonceresided(exclusively in executivesuites)under the nameExecutiveInformationSystems.Hegivesexamples of howdashboards are beingusedandspeaks of theirbenefits,butleavesittoustopiecetogetherasense ofwhat they are. The closesthecomestoadefinitioniswhenhequotesJohnHagerty of AMR Research, Inc.:"Dashboardsandscorecards are aboutmeasuring."Whileconductinganextensiveliteraturereview in 2003 in search of agoodworkingdefinition,IvisitedDataWarehousingOnline.comandclickedon the linkto"ExecutiveDashboard"articles. In response,Ireceived the same18webpages of links that IfoundwhenIseparatelyclickedonlinksfor"BalancedScorecard,"" ;Data QualityandIntegration,"and" ;Data Mining."Either the linksweren'tworkingproperly,orthiswebportalfor thedata warehousingindustryat the timebelieved that thesetermsallmeant the samething.3Ifinallydecidedtobegin the task of devisingaworkingdefinition of myownbyexaminingeveryexample of adashboardIcouldfindon the Web, in search of theircommoncharacteristics.Youmightfinditinterestingtotakeasimilar...
... residue for the configuration of the secondary structure ofthe protein. The replacement of P179 with Ala could alter the distance between the N-terminus and the C-terminus of eLP2, which couldthen ... leads to the high possibility that it could beinvolved inthe formation ofthe path ofthe ligand’smovement into the TM’s ligand pocket. Therefore,replacement of G159 with an Ala containing side ... prediction thatthe residues in the segment are involved inthe configuration of ageneral ligand recognition pocket for the receptors, but the residues are less important for determining the receptor...
... convexity, Jkis the maximizer ofthe entropy over Bkand the minimizer ofthe 2-norm. By the same token, the permutation matrices are minimizers ofthe entropy and maximizers ofthe 2-norm. The constantc ... regarding the concentration ofthe chromatic number were firstexamined in a seminal paper of Shamir and Spencer [14] inthe mid-80s. Theyshowed that χ (G(n, p)) is concentrated in an interval of ... such that h(3)> 0, h(4)< 0 and h(6)< 0 point-wise. Then the function f defined in (6) satisfies f(3)< 0 point-wise. The following lemma is the last ingredient inthe proof of Theorem...
... the decrease in emotional HRQL. The results underline the importance of including HRQL measures inthe evaluation of new life prolonging therapies.Published: 04 May 2005Health and Quality of ... ofthe study and helped draft the manuscript. ES participated inthe acquisition ofthe studyand helped draft the manuscript. GN participated in the interpretation ofdata and helped draft the ... decrease. The results ofthe present study show the importance of studying HRQL in a situation where there is a desperateneed for life-saving new therapies. Therefore, consistentlytaking HRQL into...
... completed, the investigators came together to collapse their lists of themes into one set of themes as reached via consensus.This process involved examining themes for commonal-ity, classifying them ... arole in managing chest pain from the point of entry, theymust acquire and demonstrate competence in diagnosing the complaint.Chest pain can have a multitude of etiologies, involves aninherently ... of conducting or coordinating a multidisciplinary research effort along this line of inquiry.Population, setting, timeframe The convenience-sample of five focus group participantsincluded two...