... and AngII, whether up-regulation of Cx43 can be antagonized by AT1 antagonists or whether sup-pressed smooth muscle cell proliferation and migra-tion by AT1 antagonists are mediated through ... seamless connections. The present study aimed to detect the expression of Cx40 and Cx43 in the artery at early stage of high fat diet induced atherosclerosis and to investigate the effects of AT1 ... Introduction Atherosclerosis is a slow and complicated pa-thological process. Vascular smooth muscle cell (VSMC) proliferation is one of the important features of atherosclerosis. The gap junction...
... point the object to an URL, provided the system has set it up in a consistent manner. This is another way that ADO allows developers to read outside data, such as from other applications or ... other applications or over the Internet. You could not do this easily with DAO. Figure A.1. The object model for ActiveX Data Objects 2.7. Most of the work is done in the ADODB module when you ... Recordset object. Similar to the DAO Recordset object, you can open the Recordset objects as read-only or dynamic. Each Recordset object also has a Fields collection. ã Stream object. This object...
... that you can use to accomplish tasks in your applications. You can see how these APIs are used in Figure 7.3. Figure 7.3. Under the covers, the SQL-DMO objects are being used to perform the ... Lookingatthe SQL Server DMF APIs The SQL Distributed Management Framework is a framework of objects, services, and components used to manage Microsoft SQL ... is a brief description of each of the APIs. We will be using the last two directly in the rest of this chapter. ã SQL-NS. SQL Namespace provides a way to actually call the Enterprise Managers...
... discussion From the land cover data and vegetation-related parameters in the Nong Son catchment, and the monthly meteorological data atthe Tra My climate station for the period of 1980-2004, the ... area, there are only four rain gauges, among those only one collects hourly data; one climatic station at Tra My; and one discharge gauge at Nong Son. In general, the hydro-meteorological station ... calculated by the Penman-Monteith equation, known as the one-step method. The approach requires data onthe land cover and related-vegetation parameters based on AVHRR and LDAS information, which...
... include the International Conference on Population and Development Programme of Action (ICPD PoA,1994), the Beijing Declaration and Platform for Action (BPfA, 1995), the Convention onthe Elimination ... ensure international commitments, such as those stated in the Convention onthe Elimination of All Forms of Discrimination Against Women (CEDAW), International Conference on Population and Development ... death and disability. e SPRINT Initiative, led by the International Planned Parenthood Federation (IPPF) in collaboration with the United Nations Population Fund (UNFPA) and other national...
... suppression:are other autophagy regulators also tumour suppres-sors? One would expect that this would be the casebut, so far, only one of the many other proteins impli-cated in autophagy regulation ... by the independent identification of BIF-1, an interactorof UVRAG, as a regulator of autophagy [5]. On the other hand, monoallelic UVRAG mutations associatedwith microsatellite unstable colon ... of the forming invagination, thereby securing the inclusion ofcargo proteins within ILVs [60]. The main link betweenPI3K-III and the ESCRT pathway is the fact thatVps27 ⁄ HRS, a core component...
... explained by their stimulatoryeffect onthe endothelial generation of PGI2and NOã.There are other propositions concerning the mechan-ism of endothelial actions of statins, e.g. the inductionof ... endothelial dysfunction in patients withatherosclerosis [8]. The great expectations for the therapeutic use of antioxidants in patients with athero-sclerosis need to be re-examined.Endothelium ... appreciatedthan it should have been. Atthe time, Bk was per-ceived as a mediator of pain and inflammation respon-sible for paralytic vasodilatation in the course of acutepancreatitis. The reasoning...
... indicated that the aorta–gonad–mesonephros (AGM) region of the embryo is aprimary source of definitive hematopoietic progenitors[32,33]. These subsequently enter the circulation andcolonize the ... (and other hematopoiesis-sup-porting organs), where they mature before migratingto the bone marrow [34,35]. Definitive hematopoiesisis initiated in the aortic endothelium region of the embryonic ... Quantitativedevelopmental anatomy of definitive haematopoieticstem cells ⁄ long-term epopulating units (HSC ⁄ RUs): roleof the aorta–gonad–mesonephros (AGM) region and the yolk sac in colonisation...
... is the phosphatase thatdephosphorylates Cdh1. Its inactivation has the mostdramatic effect on Clb cyclin degradation. CDC15 is acomponent of one of the two pathways that activateCdc14. In ... components that function atthe top of the path-way are located? She found that Tem1 (and we nowknow all other MEN components) localized to the SPB that migrates into the bud during anaphase. The MEN ... the machinery that promotes Cdc14 activation [54].Cdc14 – more than just promoting CDKinactivationA question that arises from the observation that at least two pathways control Cdc14 localization is...
... duplication events, followed by the evolution ofspecialized gene functions, as well as by the creationand loss of different exons. Both the emergence ofadditional genomic copies by gene duplication ... between the U2AF-related proteins implythat they have evolved distinct functions in relation to the control of gene expression in complex organisms.Clues to the biological processes in which these ... participate may be obtained by determining theirtissue expression patterns, elucidating their RNA-bind-ing specificities, and identifying the genes that theycontrol. Ultimately, understanding the...
... considers the bodiesof managers, how they embody the desired aesthetic of the organization, and howthey produce and are consumed by the organization. Pelzer (2002) looks at the disgust that ... traditional intellectual approaches, but one method usuallypredominated. Onthe content continuum, at one end is instrumental content thatconsiders mainstream organizational research questions ... that would seem toqualify, we think that that is not all that qualifies. To consider this further, let us look at the idea of aesthetics as connection. Bateson (1979) suggested that by aesthetiche...
... rolesin the complex network that controls cell growth andproliferation, the elucidation of the molecular path-ways that transmit information onthe growth state ofa cell population to the Pol ... phosphorylated by ERK permits Pol Ielongation, whereas hypophosphorylated UBF inhibitselongation, demonstrating that transcription elongationGrowth factorsNutrientsOncogenesNutrientsOncogenesGenotoxicTumor ... proliferation, stimulatesPol I transcription in part through phosphorylation of the C-terminal activation domain of UBF [28], under-scoring the importance of UBF phosphorylation in the control...
... grastrulation, sup-porting the scaling of the BMP activation gradientitself [20].How is the BMP activation gradient generated? The key asymmetry is the localized secretion of BMPantagonists by the ... facilitating the evolutionary adapta-tion of body size, because the pattern will automati-cally adjust with any mutation that alters body size,without the need for further adjustment of the pattern-ing ... Driesch andMorgan atthe end of the 19th century [45,46]. In addi-tion to natural variation, size is regulated also by the availability of nutrients or other growth conditions.Drosophila larvae...
... preventing the formation of the competing Orp1 Cys36-Cys82 disulfide bond. Onceactivated, the Yap1 NES that lies within the c-CRD ismasked leading to its retention in the nucleus and the up-regulation ... anion generator, was shown to operate. Underconditions favouring superoxide anion generation, Yap1is activated by H2O2formed by the dismutation of the ABFig. 1. (A) Comparison of the ... also for the res-toration of gene expression upon osmo-adaptation,controlling the extent of gene expression as well as itsduration [48]. Recently, Hog1 has been found to belocated at several...