... whether the minimal important difference of 1.5 generalizes to patientswith other diseases Patients included in our study might, however, represent patientswith advanced chronicdisease because ... (7.63) were in the range commonly encountered inpatientswithchronic disease. [26,27] A change of 1.5 points corresponds approximately to a 20% change from these baseline scores Inpatientswith substantially ... Clinic proceedings 2002, 77(4):371-383 Puhan MA, Busching G, Schunemann HJ, VanOort E, Zaugg C, Frey M: Interval versus continuous high-intensity exerciseinchronicobstructivepulmonary disease: ...
... function and exercise capacity inpatientswithchronicobstructivepulmonarydisease Int J Tuberc Lung Dis 1999, 3(10):920-926 Fayers PM, Machin D: Quality of Life The Assessment, Analysis and Interpretation ... measures for patientswithchronicobstructivepulmonarydisease (COPD) in an outpatient setting Thorax 1997, 52:879-887 Loge JH, Kaasa S, Hjemstad MJ, Kvien TK: Translation and performance of ... Aguirre-Jaime A, Celli BR: Gender and COPD inpatients attending a pulmonary clinic Chest 2005, 128:2012-2016 Anderson KL: The effect of chronicobstructivepulmonarydisease on quality of life Res Nurs...
... polymorphism and chronic inflammatory lung diseases, including bronchial asthma and COPD, suggesting that IL-17F may be critically involved in the pathogenesis of chronic inflammatory lung diseases [15] ... supporting the potential involvement of IL-17A in the phenotypic manifestations of COPD In addition, transgenic over expression of Il-17 in the alveoli of murine lung induces lung inflammation with ... and visualized with DAB/hydrogen peroxide After counterstaining with haematoxyline, sections were dehydrated in increasing ethanol gradient and 100% xylene immediately before performing LCM The...
... 349:1498-1504 CPMP/EWA/562/98: Points to consider on clinical investigation of medicinal products in the treatment of patientswithchronicobstructivepulmonarydisease (COPD) 1999 21 22 23 24 ... contributions 15 RS was involved in the concept and planning of the meta analysis and in writing and editing the manuscript; PW and MW were involved in the writing and editing of the manuscript ... M, Wisniewski M, Rickard K: Use of a long-acting inhaled β2 adrenergic agonist, salmeterol xinafoate, inpatientswithchronicobstructivepulmonarydisease Am J Respir Crit Care Med 2001, 163:1087-1092...
... environment for 24 continuous hours while wearing the ambulatory system Methods Subjects Eight subjects withchronicobstructivepulmonarydisease (COPD) who complained of cough as a prominent symptom ... a single cough followed by a throat clear during quiet breathing Representative recording of a single cough followed by a throat clear during quiet breathing VT = tidal volume; Fb = breathing ... recording is 1-min and 1-sec from the physiologic recordings LS data were visually inspected by two independent reviewers who remained blinded to the video data Each noted the time (hour, minute...
... that occurs in COPD patients [5] Interestingly, Riordan et al [27] have reported similar findings inpatientswith liver cirrhosis, a disease that, like COPD, is associated with systemic inflammation ... are patientswithchronicobstructivepulmonarydisease at increased risk of cardiovascular diseases? The potential role of systemic inflammation inchronicobstructivepulmonarydisease Circulation ... Sin DD: Association between chronicobstructivepulmonarydisease and systemic inflammation: a systematic review and a meta-analysis Thorax 2004, 59:574-580 Sin DD, Man SF: Why are patients with...
... quality of life for clinical trials inchronic lung disease Thorax 1987, 42(10):773-778 Standards for the diagnosis and care of patientswithchronicobstructivepulmonarydisease American Thoracic ... Comparison of discriminative properties among diseasespecific questionnaires for measuring health-related quality of life inpatientswithchronicobstructivepulmonarydisease American journal ... Randomised, double blind, placebo controlled study of fluticasone propionate inpatientswith moderate to severe chronicobstructivepulmonary disease: the ISOLDE trial BMJ (Clinical research ed)...
... quality of life for clinical trials inchronic lung disease Thorax 1987, 42(10):773-778 Standards for the diagnosis and care of patientswithchronicobstructivepulmonarydisease American Thoracic ... Comparison of discriminative properties among diseasespecific questionnaires for measuring health-related quality of life inpatientswithchronicobstructivepulmonarydisease American journal ... Randomised, double blind, placebo controlled study of fluticasone propionate inpatientswith moderate to severe chronicobstructivepulmonary disease: the ISOLDE trial BMJ (Clinical research ed)...
... inchronicobstructivepulmonarydisease Am J Respir Crit Care Med 2007, 175(12):1259-65 Dimai HP, Domej W, Leb G, Lau KH: Bone loss inpatientswith untreated chronicobstructivepulmonarydisease ... survival inchronicobstructivepulmonarydisease N Engl J Med 2007, 356(8):775-89 15 Lee TA, Weiss KB: Fracture risk associated with inhaled corticosteroid use inchronicobstructivepulmonarydisease ... including six with a normal BMI This suggests preferential skeletal muscle mass loss in 20% of our patients, which is in keeping with levels reported inpatientswith more severe lung disease...
... training The training was intensive starting at 80% of the patients maximum walk speed on treadmill, and included also intensive step training The patients were encouraged and supervised during ... Clinical routine rehabilitation of patientswithchronicobstructivepulmonarydisease at regional hospital 21 Changes in CRR outcome Table 11 shows the changes within groups from baseline ... in our study stresses the inequality in health and may also indicate that Clinical routine rehabilitation of patientswithchronicobstructivepulmonary disease...
... albumin Human serum albumin (HSA) is a single nonglycosylated polypeptide containing 35 cysteine residues all involved in the formation of stabilising disulphide bonds except 34cysteine In plasma, ... volunteers gave their signed informed consent The Global Initiative for ChronicObstructivePulmonaryDisease (GOLD) guidelines were used to stratify patientswith COPD by disease severity based on ... antibody in coating buffer at 4°C for hours Following incubation, the plate was washed and incubated overnight with PBS-Tween containing 5% milk The following day the plate was washed again and...
... during sleep using MPA[20] Although the maximum inspiratory slope was already at baseline within normal postmenopausal range, MPA almost doubled the slope This finding is in line with the thinking ... during the initial part of inspiration Since this index is insufficiently validated, the results should be considered suggestive and interpreted with caution At baseline, the maximum slope in ... P-values are corrected with Bonferroni method in base excess previously in awake patients[ 10] Our findings are consistent with those observed in 17 hypercapnic stable patientswith COPD, where nocturnal...
... informed consent was obtained from the patients' next of kin In cases in which patients regained the capacity to give consent, this was later obtained from them The patients were studied during ... patientswith COPD exacerbation has been limited mainly to the short-acting β2Figure (Rint) remained less than 85% of baseline in each patient Time after salmeterol administration that minimum inspiratory ... according to our findings, it is not possible to propose a fixed dosing interval for salmeterol in mechanically ventilated patientswith COPD exacerbation Instead of the use of a standard dosing...
... factor influencing the main findings Conclusions This study examined novel aspects of Rbm and vascular remodelling in large airway biopsies in current smokers with normal lung function and patients ... but not in ES-COPD Vessel staining for VEGF was increased in smokers and COPD, but especially in current smokers with COPD Figure There are fewer vessels in the LP in current smokers Bars indicate ... were in parallel layers, all of them were included in the measurement Rbm-associated vessels included those in contact with the inner surface of the Rbm, penetrating it, or embedded within it...
... deficiency patientswith granulomata [19,20] In contrast, a lower frequency of the minor allele was reported in RA patients, whereas inpatientswith idiopathic pulmonary fibrosis no association with ... factor-alpha in induced sputum from patientswithchronicobstructivepulmonarydisease or asthma Am J Respir Crit Care Med 1996, 153:530-534 28 Takabatake N, Nakamura H, Abe S, Inoue S, Hino T, Saito ... present findings in COPD, a significantly lower frequency of the TNF-α +489 GA and TNFα +489 AA genotypes was reported in RA patients as compared with controls Those RA patients carrying the minor...
... according to the UICC TNM guidelines [15] and were included in the analysis Patientswith carcinoma -in- situ were excluded from the study, since the risk of nodal metastasis is very low in these patients ... negative gastric cancer patients according to serosal invasion The disease- free survival of patientswith serosal invasion was lower than that of patients without serosal invasion Page of probably ... of serosal invasion were found to be independently associated with an inferior diseasefree survival (Table 3) The survival curves inpatientswith node-negative gastric cancers according to tumor...
... findings led to the evaluation of novel cardiovascular risk factors like chronic inflammation and malnutrition as predictors of the CVD inchronic kidney disease This multifactorial disease introduces ... challenges in predicting and treating patients early in course of CKD to positively alter patient outcome There is definitely a high prevalence of traditional risk factors like HTN, DM and DLP inchronic ... extends this finding to patientswith more preserved renal function in American population Our hypothesis that serum albumin is a significant risk factor for cardiovascular diseasein CKD patients...