... regions
including a large intron 1 ofthe HO-2 gene are required.
In summary, the present study has suggested that
the reduced expression of HO-2 protein may contrib-
ute to the maintenance of intracellular ... the intensity for the a-tubulin signal. Shown are the relative
expression levels of HO-1 and HO-2 proteins in YN-1 cells (B) and those of HO-2 protein in K562 cells (D). The intensity representing ... HO-1 and HO-2 expression
in human cell lines
We initially analyzed the effects of hypoxia on the
expression of HO-1 and HO-2 in human cell lines of
bone marrow origin, including KG1 myeloid cells,...
... for the
dynamic nature ofthe Internet and the
information that can be found on it;
3
.
The search for information is often
limited to a few Internet services, such
as the WWW. Finding information ... either of them.
The Internet services ofthe future
should aim at exactly the opposite with
tailor-made services (and interfaces) for
every individual user as the ultimate
target. Neither the ...
many brokers will permit the easy
introduction of innovations and the
rapid spread of useful ones.
Because ofthe rapid spread,
however, the original innovator
may gain little market advantage...
... non-lexicalization ofthe concepts, the lack of super
ordinates of hyponyms etc. The main contribution of this paper is to draw out the main ways
of dealing with the hurdles by investigating how an ... a basic
“change of form”, by emphasizing the “intended inthe text” as said “ Translation is
rendering a written text into another language inthe way the author intended inthe text.”
Hatim ... all the cultural words occurred in his book and put
them into the order ofthe most common typesof equivalence to the least common one. The
data can be easily find inthe table below:
Type of...
... for use in
training and testing the neural network. A large training data reduces
the risk of under-sampling the nonlinear function, but increases the
training time. To improve training, preprocessing ... reliance ofthe ANN
631
between the predicted value and the measured value.
The properties ofthe soil used for training ofthe MANN models are
shown in Table 1.
Table 1. Properties ofthe ... a number of combinations of input parameters to
determine the neural network model that gave the smallest average of
the sum square error. There is currently no rule for determining the
optimal...
... Search engines are domain-independent
in the way they treat gathered
information and inthe way they enable
users to search in it
8
. Terms in gathered
documents are lifted out of their
context, ... information
tasks (such as offering, finding or editing all
kinds of information). Many things that are
" ;In the future, it [agents]
is going to be the only
way to search the
Internet, because no
matter ... the
network searching for documents that, in
its opinion, could interest the user. The
search is driven by a user's profile built
and maintained by the Interface Agent.
Refinement of this profile takes...
... composition
influence turn-taking, and speaking time distribution. The results of this study indicate
that: (a) the cultural dimension of I-C is a predictor ofthe number of turn-takings and the
speaking ... turn-taking and speaking time duration) in small-group
decision-making meetings. The findings ofthe current study add value to a very extensive
literature on cross-cultural communicationin examining ... turn-taking and speaking time distribution. Inthe following, the construct
of turn-taking behaviors is reviewed.
Turn-taking is the ordering of moves that involve any organized interplay of speech acts.
A...
... speculators in accounting for the precipitous
decline ofthe domestic purchasing power ofthe mark. Instead
they direct his attention to the motives ofthe German Reichs-
bank in expanding the money ... tell us is that inthe past definite men
or groups of men were valuing and acting in a definite way.
Whether they will inthe future value and act inthe same
way remains uncertain. All that can ... specific
understanding be applied is not to diminish the importance of
pure economic theory inthe study of history. Indeed, as Mises
points out, economics
14 A History of Money and Banking inthe United...
... needed; the purpose or goal ofthe presentation; a preview ofthe main points or
major ideas to be covered inthe body. Next, comes the body ofthe presentation. The body is
the central part ofthe ... rewriting it for the ear, (3) practising and
revising it, and (4) organizing the visual aids. Once the learner has made an outline ofthe main
points, write the presentation. The main purpose of ... due to their poor language
knowledge, or in other words, either inadequate teaching or learning.
Basing on the findings, the thesis is concluded with several suggestions for the learners, the
teachers...
... a
well-defined hyperintensity mass inthe cervical area. The shape of
the uterine cervix is distorted inthe DWI (arrowhead). d On the
ADC map the tumor is hypointense (arrow) and the normal ... imaging technique (SENSE factor
of 2). Imaging time of DWI was 90 s for 20 slices.
Detection of uterine malignancy
The ADC values of uterine cancers are lower than of
normal tissue. On the other ... with uterine leiomyomas and a
bleeding cyst. a Axial T2-WI shows an area of hypointensity in the
center ofthe cystic component (arrow). b On T1-WI with fat
suppression the area inthe cystic...
... intense interest inthe roles
of the entire MT family inthe brain, with particular
focus on the role of these proteins inthe injured or
neurodegenerative brain.
Discovery of GIF
AD is a neurodegenerative ... loss
in the AD brain. Further investigation ofthe increased
neurotrophic activity ofthe AD brain revealed that it
correlated with the loss of a specific neuroinhibitory
factor, rather than the ... suggesting that this MT isoform has different and
distinct functions within the brain. Furthermore, the
discovery and continued investigation of this brain-spe-
cific MT isoform has led to intense interest...
... cDNA
sequences using the RACE method in both strains
revealed the presence of a single point mutation in
1337 nucleotides of BmIVD. Inthe sku mutant, the
1127th guanine from the start codon was ... acts inthe third step of leucine degradation and the
sku mutant accumulates branched-chain amino acids in haemolymph, this
mutant may be useful inthe investigation of unique branched-chain amino
acid ... surface
of the monomer, pointing toward FAD or its neigh-
bouring monomer inthe tetramer. By contrast, the
side chain ofthe mutated residue (Val376) points
toward the inside ofthe helix–loop–helix...
... of PKA inthe mitochondrial targeting of
CYP2E1
The role of PKA in mitochondrial targeting of
CYP2E1 was investigated using two approaches. The
first approach involved measuring the level of mito-
chondrial ... microsomes requires the co-
translational insertion ofthe newly synthesized protein
into the microsomal membrane, where the N-terminal
hydrophobic signal sequence ofthe protein interacts
with a ... mitochondria-targeting signal
in the yeast system.
Mitochondrial localization of intact CYP2E1
in yeast cells
Because ofthe existing ambiguity inthe literature on
the nature and extent of CYP2E1 import into...
... chondrocytes produce various chemokines stimu-
lated mainly by in ammatory cytokines, including IL-1b, TNF-a and
IFN-c. (B) Chemokines expressed inthe joint recruit leukocytes into
the joints. In addition ... regulated mainly by TNF-a.
The role of chemokines in RA pathogenesis
The chemokines listed above are implicated in RA
pathogenesis via the recruitment and retention of leu-
kocytes inthe joints. In addition ... subclasses include the CC chemokines
(where the cysteines are neighboring) and the CXC
chemokines (where the cysteines are separated by one
amino acid). The CXC chemokines mainly act on neu-
trophils...
... provided
further insight into the molecular mechanism driving the
formation ofthe covalent C115–fosfomycin adduct. A
conservative exchange of K22 to arginine maintains fosfo-
mycin binding, while ... a
rationale for these findings: the side chain amino group of
K22 engages in a salt-bridge interaction with the phospho-
nate group of fosfomycin (Fig. 5). Clearly, the guanidinium
group of arginine can, ... form ofthe protein.
The results obtained with the K22V/R120K double
mutant protein point toward a central role of arginine 120
in the conformational process occurring during catalysis.
Therefore,...