... RDH4SDR-O-RDH forms [47] is consistent with this model Furthermore, the observation that the Ddrs9 genes and the Rdh5-RDH cluster are located in paralogous chromosomes also supports our hypothesis ... range reported for diverse vertebrate enzymes The most significant difference between the amphioxus and the other retinal reductases was, nevertheless, their preference for the NADH cofactor To ... material is available online: Table S1 Oligonucleotides used for the PCR amplification ofthe different constructs Table S2 Accession numbers ofthe sequences used in this study This material is available...
... between the worlds of ideas and of experimental data The world of ideas includes theories, hypotheses, human knowledge and any other mental constructs, while the world of data consists of experimental ... Gepasi [38,43,44] Figure shows various views ofthe systems biology agenda Figure 2A stresses the importance of inductive methods of hypothesis generation; these have unaccountably had far less ... as an RC element, and this may account in part for the use of such serial devices in biology processing, frequency response characteristics ofthe detectors Of course the real system and its signal-processing...
... neurologists consider the irreversible lack of vital work of an organism as a concept of death that the BD criterion may satisfy Second, most neurologists not understand (at best) or disagree (at worst) ... This suggests that these neurologists think that clinical tests for BD produce many false-positive diagnoses of death Third, most neurologists did not understand (at best) or disagree (at worst) ... consider this a concept of death that BD satisfies [3, 6, 14] Loss of personhood, based on irreversible loss of consciousness (sentience, or agency) is necessary, but not sufficient, for death (Table...
... Linden S, Bellamy N: Selection of instruments in the core set for DCART, SMARD, physical therapy, and clinical record keeping in ankylosing spondylitis Progress reportofthe ASAS Working Group Assessments ... and discussed the benefits and risks of NSAID treatment in AS [27] Besides a good efficacy on signs and symptoms, there is evidence that continuous therapy with NSAIDs might stop the new formation ... 50% of patients reach a 50% improvement of their disease activity as measured by the BASDAI Impressive reductions of inflammatory lesions either in the SI joints or in the spine have been demonstrated...
... outcomes Identification of a core set of psychological variables from the increasingly large number on offer, and consensus on the instruments used to measure them, is one ofthe necessary steps Selfreported ... instruments, such as the EuroQol dimensions and Short-form dimensions, are primarily based on self-reported health profiles [10,11] The self -report profiles are mapped only in a second step onto societal ... directionality or causality ofthe interplay between psychological variables and health [1] Their analyses merely describe associations – nothing more, but also nothing less The strength of this study is...
... and sub-clusters Representative statements Psychosocial 1.1 Loss Loss of expectations • Limitations on fulfillment of goals in life Loss of enjoyment • Loss of enjoyment in life Loss of self ... our conceptual model, these core sets recognize the importance of support and relationships, attitudes of significant others and health professionals as predictors of disability in people with ... of these range of sufferers on a range of scales • Tests of structural invariance across groups Interpretations/applications applied to groups - supported through subsequent applications of the...
... patients for many years and potentially never come across a case of VADS Case-control study: this is the best research design for assessing the risks associated with a rare disorder such as VADS [33-35] ... the presence of one of these disorders should raise the clinician s level of suspicion However the majority of patients with VADS not have any of these diseases [48,60], so their absence does ... identified as a chiropractor [23] These studies reported on cases of patients who developed VADS some time after receiving CMT Generally in these reports the CMT was described as the cause ofthe dissection...
... extending south to the Sutter Buttes Another aquifer system, the Sutter Formation aquifer system, overlies the Upper and Lower Tuscan aquifer systems The Sutter formation originates at the base ofthe ... (gallons per minute) The Upper Tuscan aquifer system corresponds to the Tuscan Formation, units C and D, as shown in Figure The Lower Tuscan aquifer system is also exposed on the east side ofthe ... wells have been observed on the west side of this aquifer system due to the hydrostatic pressure from up gradient recharge areas to the east The Lower Tuscan aquifer system corresponds to the Tuscan...
... It also gives the story a sense of continuation .The settings within Tales ofthe City mostly occurs within San Francisco, aside from two departures These two places represent an escape from the ... his dance troop While Coward 's story is a fanciful recounting of prior experiences, a confession of sorts, Maupin 's rendering releases the pasts for a better future Death manifests because of ... events so they adhere to future events The hypocrisy ofthe social classes is brought forward Humans are frail The reading is seemingly simplistic on the surface, but beneath this there are serious...
... Beyond these market failures, the loss of rainforests represents the erosion of a resource that plays a vital role in the lives ofthe poor, in the provision of ecosystem services and in sustaining ... member states to resist the lobbying efforts of powerful vested interests Some sectors—notably power—have secured windfall gains at public expense And only a small fraction of ETS permits—less than ... future of our children and their children requires that we act now This is a form of insurance against possibly very large losses The fact that we not know the probability of such losses or their...
... withneoplastic mass, consisting of solid Gross appearance ofthe neoplastic mass, consisting of solid areas and cysts filled with clotted blood Discussion EGISTs arise outside the gastrointestinal ... [7-9] These tumors must be defined as extra-gastrointestinal stromal tumors (EGISTs) since they display no connection with the gastric or intestinal wall While the histogenesis, prognostic parameters ... By means of a critical revaluation ofthe surgical reports and clinical histories and a careful search for residual muscular tissue from the gut wall in the tumor pseudocapsule, it was possible...
... swelling ofthe dorsal aspect ofthe right side of her neck without signs of vascular obstruction or venous stases No abnormalities of neural status ofthe head and neck were observed There was no ... for smooth muscle markers facilitates the correct diagnosis The intravascular leiomyomatosis is characterized by the proliferation of smooth muscle vascular structures ofthe uterus or its surrounding ... includes the spectrum of spindle cell shaped neoplasm Mesenchymal tumours, the benign and malignant tumours ofthe nerve sheaths myofibrolastic tumours (myofibromatosis, fibromatosis, myofibroblastic...
... 27.5% of trunk and extremities MPNSTs, respectively The rarity of intracranial MPNSTs hampers the establishment of evidence based strategies for their optimal treatment Thus, the management ofthe ... decided to be spared for the case of tumour relapse or metastatic disease In the present patient the MPNST seems to have resulted from the malignant transformation of a preexisting benign schwannoma ... adjuvant stereotactically guided radiotherapy This strategy minimises the possible complications of surgery as well as of brain radiation Chemotherapy should probably be spared for relapsed or metastasized...
... Larger tumors are more likely to be malignant and are associated with the worst prognosis [3,5,6] The presence of symptoms and pleural effusion, which are also reported as factors associated with ... compressed the lung, the descending aorta and other mediastinal structures strongly, the patient had no symptoms except malaise and had normally worked as a furniture remover We successfully resected ... http://www.cardiothoracicsurgery.org/content/6/1/122 Page of Figure Microscopic examination of solitary fibrous tumor ofthe pleura (A, B) Microscopic specimen ofthe tumor shows solid proliferation of spindle-shaped...
... appearance ofthe oral neurofibroma is characterized by a whitish consistent mass with shiny sur- Figure Tumor mass after resection Tumor mass after resection face Microscopically the tumor is composed ... composed of an irregular pattern of proliferative spindle cells The stroma is composed of collagen fibers and mucoid masses Small axons all over the tumoral tissue are demonstrated with silver staining ... nerve as origin for the neurofibroma The patient presented no signs of von Recklinghausen disease or poliglandular syndrome Preoperative panoramic radiographs showed no serious abnormalities Definitive...
... Some sections were stained with haematoxylin-eosin Histologically, the tumor is solid and there is a cyst formation (Fig 2) The epithelium is in the form of whorled masses of spindle cells as ... our case supports the above mentioned general description of AOTs Competing interests All authors disclaim any financial or non-financial interests or commercial associations that might pose or ... whereas most tumor droplets reveal electron-dense plaques [15] Interestingly, there are a few reports about pigmented cells in AOT However, all of these reported lesions did not show macroscopically...
... misdiagnosis of cyst or benign soft tissue neoplasm; it is frequently mistaken for lipoma [12] Liposarcoma has been described as more firm, less easily compressed and more fixed to adjacent tissue than ... gross inspection, as less yellow and less lobulated [12,21] Nonetheless, many authors report difficulty in distinguishing these entities [21,22] and therefore histopathology is required for an ... L, Favia G: Liposarcoma circumscriptum (lipoma-like) ofthe tongue: reportof a case Oral Dis 2004, 10:398-400 Hajdu SI: Tumors of Adipose Tissue In Pathology of Soft Tissue Tumors Philadelphia:...
... patients with a skelettal class III jaw relationship have a poor chance of successful oral rehabilitation if they are provided exclusively with implant-supported prostheses unless supplementary surgery ... advantages and satisfactory long-term results ofthe one stage procedure [4,15], but others prefer the two stage method as the longterm results are slightly superior to the one step procedure and simultanous ... angulation ofthe inserted implants [16-18] A similar variant ofthe maxillary sandwich osteotomy for the rehabilitation ofthe severely atrophied maxilla is the horseshoe Le Fort I osteotomy where the...
... Transport * For the buildings, forestry, waste and transport sectors, the potential is split into three cost categories: at net negative costs, at 0-20 US$/tCO2, and 20-100 US$/tCO2 For the industrial, ... one ofthe most formidable challenges ofthe 21st century IPCC s Fourth Assessment Report showed that: The challenge is Herculean However, many ofthe solutions exist A large share of these ... - Slovakia, Svn Slovenia, Sw - Switzerland, Swe - Sweden, Tha - Thailand, US - United States 3CSEP Results ofthe analysis of studies For studies reviewed (see Table on the next slide and Annex...
... on the list of employment requirements for graduates, important factor of employability • English plays a significant role, but two or more languages necessary • National languages necessary for ... quality of work Negative influence on competitiveness Sub-project Conference West Main consequences for skills and competences needed for sustainable employability et competitiveness (1/2) Professional ... society – increase in number of languages spoken • Foreign investment esp USA (ICT sector) – English-speaking with broad access to the European market • Booming construction and service sectors/manpower...