understanding the role and potential of infusion nanoelectrospray ionization for pharmaceutical bioanalysis

analytical method validation and instrument performance verification

analytical method validation and instrument performance verification

Ngày tải lên : 03/06/2014, 01:15
... function of concentration of the analyte The plot of the data should normally yield a straight line This is especially true for pharmaceuticals of synthetic origin Other forms of mathematical ... information of the stability of the API and drug product Therefore, open dish (i.e., nonprotected) stability studies are carried out to understand the chemical and physical stability of both the ... peak areas The ratio of the peak height or area of the analyte to an internal standard is determined The ratios of the standards 14 POTENCY METHOD VALIDATION are plotted as a function of the concentration...
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FOREST AND PAPER INDUSTRY - A mature industry that has done much to clean up its act. pptx

FOREST AND PAPER INDUSTRY - A mature industry that has done much to clean up its act. pptx

Ngày tải lên : 09/03/2014, 00:20
... L) of water for processing into paper The production of metric ton of paper requires 17 trees (in average) 24 trees for white office paper, 12 trees for newsprint 25 m3 of water 10,061 kWh of ... brute force is applied… = energy consumption From chips to pulp Here, the process is chemical The purpose of this step is to remove the lignin (= glue) that holds the wood fibers together The product ... (http://www.biomatnet.org/secure/Fair/S502.htm) Those handy Post-It ® 19 Progress is being made with recovery of paper for recycling For reference: - The American Forest & Paper Association had set a recycling target of 55% for 2012 We...
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báo cáo hóa học: " Method optimization and validation for the simultaneous determination of arachidonic acid metabolites in exhaled breath condensate by liquid chromatography-electrospray ionization tandem mass spectrometry" doc

báo cáo hóa học: " Method optimization and validation for the simultaneous determination of arachidonic acid metabolites in exhaled breath condensate by liquid chromatography-electrospray ionization tandem mass spectrometry" doc

Ngày tải lên : 20/06/2014, 00:20
... solution for the preparation of the other standard concentrations for calibration and quality control material For the preparation of internal standards solutions commercially available [2H4] LTB4 and ... deviation of the between-day repeatability for the Q1 and Q2 level ranged from 4–16% and from 6–12% respectively Accuracy was obtained from the ratio of the calculated and the nominal amount spiked for ... some of the structural isomers of prostaglandins, which resulted in the same parent-daughter ion transitions The whole analytical run time, including the recondition step of the column for the...
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Báo cáo y học: " Validation and extension of an empirical Bayes method for SNP calling on Affymetrix microarrays" pot

Báo cáo y học: " Validation and extension of an empirical Bayes method for SNP calling on Affymetrix microarrays" pot

Ngày tải lên : 14/08/2014, 08:21
... SL and RAI conceived the study, developed the software, and drafted the manuscript AC conceived the study, provided the data, and revised the manuscript BC conceived the study, developed the software, ... calculating the following value for each SNP: minimum distance between the center of region AA and AB and the center of AB and BB Finally, we noted that accuracy is slightly different for homozygous and ... deriving the gold standard For each SNP, calls for the three genotypes are tallied across the replicates The genotype comprising greater than 50% of the calls is designated the gold standard call...
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Anchorage and resistance to uprooting forces of eelgrass (Zostera marina L.) shoots planted in slag substrates

Anchorage and resistance to uprooting forces of eelgrass (Zostera marina L.) shoots planted in slag substrates

Ngày tải lên : 05/09/2013, 09:38
... hydraulic forces (Handley and Davy, 2002) In their study, Handley and Davy (2002) suggested that the size of substrate particles and closeness of packing were likely to affect the rooting of aquatic ... investigate the effect of a test substrate on the root-rhizome system of the eelgrass The change in the number of rhizome nodes and data of below-ground biomass are given in Fig These data further showed ... whether particle size can affect the ability of slag to anchor the roots of the eelgrass plants and (3) to investigate how sedimentation of fine particles affects anchoring of the eelgrass in the...
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Optimal cost and allocation for UPFC using HRGAPSO to improve power system security and loadability

Optimal cost and allocation for UPFC using HRGAPSO to improve power system security and loadability

Ngày tải lên : 05/09/2013, 15:28
... of the UPFC Yp is the admittance of the parallel component The injected real and reactive powers for all buses of the system with UPFC remain same as those of the system without UPFC except for ... active and reactive power -Control of the voltage changes the flow units for the calculation of reactive power 2.2 Mathematical model of power systems with UPFC devices The objective of this ... algorithm for optimally locating the UPFC in electrical power system In order to take advantage of the peculiarities of RGA and PSO, the proposed algorithm integrates the main features of them into the...
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Tài liệu Windows Registry Clean up pptx

Tài liệu Windows Registry Clean up pptx

Ngày tải lên : 24/12/2013, 02:15
... up your list of installed applications and make sure they are all gone? Use the above hack to get those programs off the list Next step is to scan the registry for keys related to these applications ... tool invaluable For the most part they are quick, thorough and eliminate the possibility of human error Editing the registry is a tedious task that I would gladly hand over to the right tool I ... Registry repair and system optimization as a professional First off by the time I get a computer it is in bad shape mainly because the repair shop is always the last ditch effort before the system...
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Tài liệu HARBORING POLLUTION: Strategies to Clean Up U.S. Ports doc

Tài liệu HARBORING POLLUTION: Strategies to Clean Up U.S. Ports doc

Ngày tải lên : 17/02/2014, 11:20
... Figure E-1 uses the Port of Los Angeles and the Port of New York and New Jersey as examples because they are the largest ports on the West Coast and East Coast, respectively The Port of Virginia ... of older engines, the hours the vessel operates, the age of the vessel’s engines, the timetable for replacement, and the willingness of the tugboat owner/operator to remain in the same coastal ... maintenance on the engine, the duty cycle, and many more factors The amount of sulfur in ship emissions is equivalent to the amount of sulfur in the fuel Therefore, the amount of SOx that will...
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Tài liệu DIVISION OF HEALTH CARE FINANCING AND POLICY MEDICAID AND NEVADA CHECK UP FACT BOOK pdf

Tài liệu DIVISION OF HEALTH CARE FINANCING AND POLICY MEDICAID AND NEVADA CHECK UP FACT BOOK pdf

Ngày tải lên : 18/02/2014, 15:20
... development and cost containment functions of the division The Chiefs of Compliance, Audits, Health Care Reform and Information Services direct their respective units The rest of the support staff in the ... had the option of organizing their program in the form of a new CHIP, expanding Medicaid coverage, or establishing a combination of these two approaches There are options for administration of these ... improve the efficiency and effectiveness of the health care system by adopting standards for the electronic transmission of health care information as well as standards to ensure the privacy and...
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Tài liệu Helpful Hints for Clean-Up pdf

Tài liệu Helpful Hints for Clean-Up pdf

Ngày tải lên : 21/02/2014, 15:20
... unless the style of the picture is very loose) Straight against Curve - Use straight lines for tension, strength, hard areas like knees and elbows Curves for flow, sag and softness Let them play off ... of the rough animation Lack of communication breeds suspicion in the unit Don’t re-invent the character - Stick by the assistants keys and the model sheets Any "additions" or "subtractions" of ... lines in clothing, skin folds etc Where’s the focus? Spend the most time and effort in the area(s) of focus (ie: The face - eyes especially, or hands if they’re involved in some business) Know...
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Tài liệu EGERTON RYERSON AND Education in Upper Canada docx

Tài liệu EGERTON RYERSON AND Education in Upper Canada docx

Ngày tải lên : 21/02/2014, 21:20
... to the Assembly, proposed that five out of seven of the governing body should be permanently of the faith of the Church of England The other two members were to be the Lieutenant-Governor and the ... on the College Council to the Speaker of the two branches of the Legislature and to the Attorney-General and the Solicitor-General of Upper Canada; they removed from members of the Council and ... President of the Executive Council, the Speakers of the two branches of the Legislature, and the Attorney-General and the Solicitor-General for Canada West were to be ex-officio visitors and members of...
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Menopause and Osteoporos is Update 2009 ppt

Menopause and Osteoporos is Update 2009 ppt

Ngày tải lên : 05/03/2014, 16:20
... postmenopausal women in the WHI,18 the other that there may exist a critical window for neuroprotection The clinical importance of these studies is that they showed no benefit, and the potential for harm, ... fails to delay the progression of disease.11–13 The data on the role of HT for primary prevention of CVD have been the primary reason for the ongoing debate Whereas data from a variety of sources ... orange choices and the other of additional choices After making selections and clicking on “Next,” the woman is presented with the other categories of food in turn and then categories of physical...
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World Economic Situation and Prospects 2012: Update as of mid-2012 docx

World Economic Situation and Prospects 2012: Update as of mid-2012 docx

Ngày tải lên : 08/03/2014, 06:20
... 2011/522/CFSP of September 2011 and 2012/35/CFSP of 23 January 2012 for the EU bans of Syrian and Iranian oil imports and Executive Orders 13582 of 18 August 2011, and 12959 of May 1995 for those ... most of the region is forecast to be in the low single-digits The region remains dependent on external finance, and the large presence of Greek banks in parts of the region entails the risk of ... droughts, especially in the Horn of Africa and the Sahel region Update as of mid-2012 Risks and uncertainties Given the fragility of the global economy, the baseline outlook for 2012 and 2013 is subject...
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TYPE 2 DIABETES - National clinical guideline for management in primary and secondary care (update) pdf

TYPE 2 DIABETES - National clinical guideline for management in primary and secondary care (update) pdf

Ngày tải lên : 08/03/2014, 14:20
... educational theory appropriate to the age and needs of the programme learners, and be trained and competent in delivery of the principles and content of the specific programme they are offering The programme ... managed by the person with the diabetes and/ or their carer as part of their daily life Accordingly, understanding of diabetes, informed choice of management opportunities, and the acquisition of relevant ... and Susan Tann of the NCC-CC for their support throughout the development of the guideline The GDG would like to thank the following individuals for giving their time to advise us regarding the...
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 nanotechnology and electronics presentation updated september 2011

nanotechnology and electronics presentation updated september 2011

Ngày tải lên : 15/03/2014, 22:06
... to show the 3D view of that part of the circuit Drag the scale tool in the locations on the chip to record the measurements Drag the height tool between locations on the chip to record the measurements ... Microscope Software Updated September 2011 Choose the integrated circuit Change the color scheme to HSV Use the scroll wheel on the mouse to zoom in and out Toggle the AFM and draw a box on the chip ... opinions, findings and conclusions or recommendations expressed in the material are those of the author and not necessarily reflect the views of the National Science Foundation or the Oklahoma Nanotechnology...
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Blank values, adsorption, pre concentration, and sample preservation for arsenic speciation of environme

Blank values, adsorption, pre concentration, and sample preservation for arsenic speciation of environme

Ngày tải lên : 15/03/2014, 23:22
... rainwater was used to fill the bottles of different materials The bottles were shaken in the dark at ± ◦ C and 20±1 ◦ C for 24 h, and ml of the solution was taken for the analysis of the arsenic compounds ... intermediate of AsB and AsC [12], the abundance of DMA after incubation was caused by the degradation of AsB and AsC The results from the control experiment indicate the essential steps to reduce transformation ... analytical possibility for arsenic compounds at the level of ng As l−1 , and has high recovery and low transformation Addition of EDTA and storage in the dark can reduce the transformation among arsenic...
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Báo cáo khoa học: Dictyostelium differentiation-inducing factor-1 induces glucose transporter 1 translocation and promotes glucose uptake in mammalian cells pdf

Báo cáo khoa học: Dictyostelium differentiation-inducing factor-1 induces glucose transporter 1 translocation and promotes glucose uptake in mammalian cells pdf

Ngày tải lên : 23/03/2014, 09:20
... further incubated with fresh media in the absence of EtOH or DIF-1 for 18 h The glucose concentration of each well was measured at the indicated time points, and the mean ± SD (bars) values of the ... well-established model cells suitable for the analysis of the actions of insulin and other insulinomimetic substances in adipocytes Thus, we examined and compared the effects of DIF-1 and insulin on glucose ... because DMEM-LG rather than DMEM-HG was suitable for the precise measurement of the glucose concentration by the use of a blood glucose test meter Therefore, to standardize the experimental conditions,...
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Báo cáo khoa học: Structural studies of thymidine kinases from Bacillus anthracis and Bacillus cereus provide insights into quaternary structure and conformational changes upon substrate binding pot

Báo cáo khoa học: Structural studies of thymidine kinases from Bacillus anthracis and Bacillus cereus provide insights into quaternary structure and conformational changes upon substrate binding pot

Ngày tải lên : 23/03/2014, 09:21
... interaction One is formed between helices a1 of two neighboring subunits, and the other is between the edges of the b-sheets The subunit comprises two domains, the N-terminal a ⁄ b-domain and the C-terminal ... inhibitor Whether it binds in one or the other direction is primarily determined by the affinity of the base of the dNTP for the substrate site Normally, the preferred bisubstrate inhibitor is the dNTP ... form The observation that, in Bc-TK, the base of dTTP in the phosphate donor position is inserted between two subunits implies that the enzyme was in the dimeric form before the formation of the...
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east asia and pacific economic update 2011. navigating turbulence, sustaining growth

east asia and pacific economic update 2011. navigating turbulence, sustaining growth

Ngày tải lên : 26/03/2014, 14:09
... innovating firms and they often earn more than those with less education 27 More than half of the manufacturing firms in Thailand, Cambodia, and Malaysia offer formal training for their workforce, suggesting ... from the 2009 crisis and the growth momentum is expected to continue The recent floods and the slowdown in the EU and U.S economies have slowed growth over the second half of the year, but the ... in the tourism sector, and the moderate growth of the agricultural sector has offset the negative growth in the construction and real estate sectors over the first half of 2011 Growth in the...
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