... with RA to that ofpatientswith PsA [4], the mean number of active joints inpatientswith PsA was 6, while the baseline mean number of tender and swollen joints for patientsin the IMPACT II ... (b), and ankylosing spondylitis (AS) (c) in infliximab clinical trials patientswith AS, the change from baseline to week 24 in PCS was 9.9 in the infliximab group compared with 0.7 in the placebo ... PsA and 19% ofpatientswith AS were women Most patients had well-established disease, with average disease durations of 10.2 years for patientswith AS, 10.0 years for patientswith RA, and...
... findings of CTs conducted before inclusion of the patientsin the study The CT findings on inclusion were regarded to be the worst of the hospital stay; the prognostic value of such CT findings ... and/or vasoactive support with norepinephrine (noradrenaline) Inpatientswith ICP greater than 20 mmHg, initial treatment included elevation of the head of the bed, keeping the neck straight, appropriate ... Thoracic injury 0.13 Abdominal injury 0.34 Extremities injury 0.20 Diffuse injury without brain swelling 12 0.046 Diffuse bilateral brain swelling 12 Diffuse unilateral brain swelling with midline...
... Journal of NeuroEngineering and Rehabilitation 2009, 6:13 Background Postural instability is one of the cardinal symptoms of Parkinson's disease (PD), and persons with PD run an increased risk of ... assessments of fear of falling have not previously been included in studies when investigating the effect of STN stimulation In the present study, the patients rated their fear of falling as less ... test: two patients) The patients rated their fear of falling as less severe with DBS ON as compared to DBS OFF, and the total score of FES(S) increased (p = 0.002) in median with 54 points (Table...
... Inactivation of the VHL tumour suppressor gene is thought to result both in development of tumors in the von Hippel-Lindau (VHL) disease (MIM #19330) and in sporadic clear-cell RCC [4] Germline ... (12 of 17) of the formalin-fixed samples, and 38% (10 of 26) of the Bouin's fixed tissues Thus, the VHL gene was entirely sequenced (ie 100% of the coding sequence analysed) for a total of 26 ... ppm.years with peaks) other chlorinated solvents, cutting oils, lead, ionizing radiations, asbestos and welding fumes 20 pack-years < 25 of missense mutations is different in the two groups with 68% of...
... systematic review of interventions to improve outcomes ofpatientswith CHF through changing care delivery processes in clinical settings is consistent with literature reporting that interventions ... nature of the disease or diseases of the patients being cared for Diseases may mediate the way that interventions influence a patient’s care The level of complexity of different diseases, and ... review of interventions to improve outcomes for patientswith Type diabetes, expanding the data regarding the importance of considering health care settings as CAS beyond a single chronic disease...
... all subjects In addition, patients were clinically evaluated with disease- specific severity scales, and with standardised instruments measuring disability and quality of life Sample Patients had ... contains 36 items on functioning and disability with a recall period of 30 days[8] covering domains: Understanding and Communicating (6 items), Getting around (5 items), Self-care (4 items), Getting ... each domain by adding the item responses (the score computation allows for up to 30% of missing items per domain) and transforming them into a range from to 100, with higher scores indicating higher...
... [1]: diseaseof the middle ear and/or mastoid with irreversible mucosal damage or infection lasting more than months This definition covers adequately the clinical course and findings in our patients ... completed in July, 2008 PatientsIn this study, patientswith chronic suppurative mesotympanic or epitympanic otitis media were included For the purposes of this study, the definition of CSOM according ... [3] was inapplicable This definition is accurate from the academic point of view but much too diversified for use in clinical studies Therefore, inclusion in the study was determined according to...
... classified in major categories, including: treatment for RA flare (including treatment for severe pain and joint aspiration and injection), single or multiple diagnostic tests requiring admission, ... hospital within one year The number and frequencies for hospital admissions appear in Table Regarding the length of hospitalisation, 32 patients (out of the 94 patients admitted) stayed as inpatients ... outcomes (by promoting beneficial body composition changes and reducing fatigue), inhibit progression of the disease (by reducing inflammation and increasing muscle mass and bone mineral density),...
... patients are as severe (and in many respects more so) than those reported in studies ofpatientswith other severely debilitating and life-threatening conditions such as spinal cord injury, interstitial ... Blackburn SD, Crow JW, Rubin LJ: Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, inpatientswith pulmonary arterial hypertension: a double-blind, randomized, placebo-controlled ... quality of life inpatientswith COPD Chest 1995, 107:1585-1589 Lucke KT, Coccia H, Goode JS, Lucke JF: Quality of life in spinal cord injured individuals and their caregivers during the initial...
... Only initial TOI was a clinically meaningful predictor of follow-up TOI, with a SD increase (12.7 points) in initial TOI scores corresponding to a 6.4 point increase in follow-up TOI scores Initial ... problems withTreatment Information was also retained in the model for follow-up TOI A measure of perceived quality oftreatment information is not commonly included in studies aimed at identifying ... HRQL The percent ofpatientswith a clinically meaningful decline in EWB scores from the initial to follow-up survey was exactly the same as the percent with a clinically meaningful improvement...
... symptomatology, including pain and itching, combined with concerns about the appearance of one's skin can substantially affect a patient's psychological well-being and can result in emotional distress, ... the magnitude of change in HRQOL scores is not well-characterized There is currently little guidance for interpreting changes in HRQOL scores Most often information on minimum clinically important ... Assessment of at least moderate disease The REVEAL study was conducted in accordance with the principles of the Declaration of Helsinki, and all study sites received approval from independent...
... trial of oncedaily ruboxistaurin for vision loss inpatientswith diabetic retinopathy The clinical findings and characteristics of this trial have been reported previously [22] A total of 684 patients ... this link over time Thus, the purpose of the current study was to examine the degree of change in HRQL that is associated with visual acuity changes among patientswith diabetic retinopathy Patients ... validated in samples combining patientswith a range of eye conditions including cataracts, macular degeneration, diabetic retinopathy, glaucoma, or low vision from any cause [25,35] In the current...
... quality of life ofpatients participating in the current study seem to be in accordance with scores ofpatientswith fibromyalgia participating in other studies For patientswith fibromyalgia in the ... decreased pain tolerance and a higher level of disability Although the construct of fear of injury is also applicable inpatientswith fibromyalgia, the mean score on fear of injury ofpatientswith ... pain and long term false straining of the muscles eventually can result in chronification of pain In accordance with the hypothesis of Hasenbring, Van Houdenhoven suggested that, especially in...
... psoriasis patients Various factors may be attributed to the lower QoL in psoriasis patients The chronic and recurring nature of this disease often brings about a feeling of hopelessness in terms of ... "Infliximab treatment results in significant improvement in the quality of life ofpatientswith severe psoriasis: a double-blind placebo-controlled trial" (2005) [43] Intravenous infusions of ... nm): efficacy inpatientswith severe psoriasis" (2000) [49] "A comparison oftreatmentwith dithranol and calcipotriol on the clinical severity and quality of life inpatientswith psoriasis"...
... and inform clinical decision making Utility assessment is a particularly appealing quality of life measure because it incorporates all aspect of health into a single number (between and 1) with ... endpoints of death and perfect health [16] Methods PatientsPatientswith documented (by histology) Barrett's esophagus over the age of 18 who were either having an endoscopy or a clinic visit within ... making them an informed and realistic patient population facing these decisions Although patientswith HGD or prior HGD were excluded, patientswith prior LGD were included The description of...
... presented in Table The results of the scales of SF-36 between the two time intervals inpatientswith anogenital warts and in the control group are presented in Table In this Table, the scores of the ... improvement in the scales of vitality and mental health and a deterioration in the scale of social functioning in anogenital warts patients between the time of diagnosis and initiation oftreatment ... participated in generating and gathering the data the data and in writing the manuscript EN participated in generating the data and in writing the manuscript MH participated in the design of the study...
... associated with health-related quality of life inpatientswith COPD Also, we also did not include generic questionnaires like the SF-36, in the evaluation of the QoL of these patients, as some investigators ... time in 2002, the number of women dying from this disease surpassed that of men Quality of Life has become an important measurable outcome inpatientswith Chronic Obstructive Pulmonary Disease ... [5] In the literature there are few reports suggesting a greater impairment in health related quality of life in female patientswith COPD [6-10] Several studies completed mainly in men with...
... trial of oncedaily ruboxistaurin for vision loss inpatientswith diabetic retinopathy The clinical findings and characteristics of this trial have been reported previously [22] A total of 684 patients ... this link over time Thus, the purpose of the current study was to examine the degree of change in HRQL that is associated with visual acuity changes among patientswith diabetic retinopathy Patients ... validated in samples combining patientswith a range of eye conditions including cataracts, macular degeneration, diabetic retinopathy, glaucoma, or low vision from any cause [25,35] In the current...
... Results Patients A total of 117 patientswith GOLD stages III and IV participated in the study Patient characteristics by disease stage are shown in Table A total of 71% ofpatients had stage IV disease ... to those with missing SF6D, but disease severity did not differ between patientswith available and missing scores In all instruments, missing items were more frequent in women than in men (11% ... different disease severities The main problem of the SF-12 in this self-administered setting was the high proportion of missing values For less than 55% of all patients, a comparison of utility...
... while according to one study it is associated with alexythymia in cases of panic disorder [21] Suicidal ideation and thinking of death is nonetheless a common feature of the thinking of depressives ... (most of whom were treated with antidepressants) among patients having suicidal ideation at baseline, the decline in suicidal ideation was predicted by preceding declines in the levels of both ... threshold is present In addition to serotonin, behavioural inhibition may be regulated by noradrenalin and dopamine, which play a role in the regulation of serotonin release [35] Research indi- http://www.annals-general-psychiatry.com/content/6/1/23...