... distribution of the world’s urban population andthat of the urban population of each of the 14 regions are shown in Figure 1. To allow the most appropriate epidemiologic studies to be used for ... therefore, to make assumptions concerningfactors such as the transferability of risk functions, exposure of the population,and its underlying vulnerability to air pollution, while trying to ensure ... dataexist, as they currently do in some parts of the world, they should of coursebe used.Future estimates of the global burden of disease dueto outdoor air pollutionwould benefit from both...
... thank Dr. Yoshitaka Matsumoto for his contribution to this study. We are grateful to Prof. Yasushi Sakamoto and Prof. Futaba Kazama for their scientific suggestions, to Rezina Ashraf, MBBS, who ... water treatment (Sobsey 2002; Sobsey et al. 2003). In addition, water used for washing hands might have been contaminated, probably by secondary contamination dueto storage, as some of the storage ... durations of morbidity (Murray et al. 2002). DALYs, dueto premature mortality, are calculated using standard expected YLL from model life tables and, dueto disability from age a to age (a...
... activity of Fat1p alone was not strong enough to prevent thesecretion of fatty acids upon combined deletion of FAA1 and FAA4. To allow for speculation about the biological role of the release of fatty ... 18:1 to 18:2 [25,26]. Dueto the nature of this desaturase, thegenerated 18:2 was considered as marker for the pool of bound fatty acids. Therefore, the occurrence of 18:2in the pool of free ... release of the fatty acids is ratherunspecific.The direction of fatty acid transport is dependenton the metabolic state of the cells To gain further insight into the correlation of growthphase of...
... ‘Kla goes out to seek Laay in the cane fieldand he finds that it is about to walk away.’The sentence in (17) are split into two SVCs: theseries of V1 to V3and the series of V4 to V5, be-cause ... incorporated withvariable quantification to resolve pro-forms andVP ellipses to their antecedents. The variablequantification in TLG is comparable to the use of memory in storing antecedents and anaphora.13(30) ... in registers for being filled to gaps foundin the rest of the input sentence. These regis-ters are too powerful since they enable ATN to recognize the full class of context-sensitive gram-mars....
... of which 20 (83.3%) of the retreatment cases were reportedly dueto relapse, 2(8.3%) dueto default and another 2 (8.3%) dueto treat-ment failure; Only 22 (9.1%) of the patients had all spu-tum ... respectively).Age, gender, type of facility, level of education and oc-cupation were found to be significant predictors of thetotal income lost (by patients and household) dueto TBdisease. AFB sputum-smear ... found to be significant predictors of thetotal time spent. Age, gender, AFB sputum-smearresults, level of education, HIV status and occupationwere not significant predictors of the total time...
... PCM)Programmed automatic ESD-Sequences(e.g. ESD-Pushbutton, Shut-Down dueto Communication Failure)UN4. 4. Pipeline IntegrityPipeline Integrity--Design and Review of Design and Review of Safety ... and Terminologyb) Purpose of (Pipeline) SCADA systemsIntegration of field equipment (e.g. actuator, sensor or pump) and small scale (unit) automation systems to the control centre computer ... and Review of Design and Review of Safety Integrity Level (SIL)Safety Integrity Level (SIL)3. national regulatory authorities expect it from us as prudent operators4. Allows us to focus testing...
... attributable to road traffic All the above mentioned restrictions for the assessment of health costs dueto air pollution reduces thecosts by a factor of 3.6 (in Switzerland) up to a factor of 9.1 ... population of Austria, France and Switzerland is subdivided into categories of exposure to different classes of pollution levels from a superposition of the mapping of ambientconcentration of particulate ... does not try to assess thevalue of a specific life. What is being measured is the benefit of a risk reduction dueto a lower level of air pollution leading to a decrease in frequency of the different...
... adjacent to theC-terminal residue of PE was essential for cytotoxicity[73]. Deletions in the REDL sequence of PE eliminateits cytotoxicity, although replacement with a similarsequence, KDEL, restores ... target receptoris changed. This could potentially influence cytotoxic-ity in a variety of ways, from changing the number of receptor sites per cell to altering the rate of internali-zation of the ... strides to generate the immunotox-ins of today and, we anticipate, the medicines of tomorrow. Advances in our understanding of PE andits intoxication pathway have fueled the translation of basic...
... USA). To improve ampli®-cation of the extremely GC-rich repeats, betaine was a dded to each reaction to a ®nal concentration of 2M(Sigma,St Louis, MO, U SA). A pair of primers, referred to asBSSL ... human hepa-toma cell line HepG2 also expresses a BSSL isoform of lower molecular m ass [ 40]. The cDNA sequence of t hisisoform contained only one ÔrepeatÕ.The obvious question is, of course, ... epeated region of the BSSL gene makes i ttempting to speculate that FAPP is identical to a naturallyoccurring low molecular mass variant of BSSL. Thecharacteristic FAPP epitope should then...
... differentiation and evasion of apoptosis [1]. Evasion of apoptosis has beenobserved in both haemopoietic and epithelial cells witha variety of agents and suggests that Evi1 is a survivalfactor. For example, ... and had noeffect upon apoptosis induced by treatment with taxol(Fig. S2).caIII expression was restored in 5.61 cells to deter-mine if the sensitivity to H2O2 treatment could bereverted. ... Evi1 is a survivalfactor, protecting cells from apoptosis induced by avariety of agents. To determine if Evi1 also protectsRat1 cells from apoptosis, we treated our panel of cellpopulations...
... minimum inhibitory concentration may increase toxin release and stimulate toxin production [37, 38, 51]. The former effect is dueto release of intracellular toxin secondary to cell wall lysis. ... a consequence of extensive tissue necrosis, leading to poor antibiotic diffusion and a sepsis-related increase of the volume of distribution. However, the stimulatory effect on toxin release ... PA, Etienne J: Favorable outcome of pneumonia dueto Panton-Valentine leukocidin-producing Staphylococcus aureus associated with hematogenous origin and absence of flu-like illness. Eur J Clin...