... acquisition of data, and to the analysis and interpretation of data JAL, CR, AP, JN, FA, and MMP were involved in drafting the manuscript and revising it critically for important intellectual ... independent predictors of mortality Thus, ARF as determined by RIFLE is common among patientswith sepsis, and increases mortality Age, gender, chronic kidney disease, Gram-negative-related infection ... et al intermittent hemodialysis) The mortality rate was 37.4%, and increased from ‘normal’ to failurePatients who did not die had renal function recovery Multivariate analysis including age...
... findings of CTs conducted before inclusion of the patientsin the study The CT findings on inclusion were regarded to be the worst of the hospital stay; the prognostic value of such CT findings ... Thoracic injury 0.13 Abdominal injury 0.34 Extremities injury 0.20 Diffuse injury without brain swelling 12 0.046 Diffuse bilateral brain swelling 12 Diffuse unilateral brain swelling with midline ... and/or vasoactive support with norepinephrine (noradrenaline) Inpatientswith ICP greater than 20 mmHg, initial treatment included elevation of the head of the bed, keeping the neck straight, appropriate...
... should not be used inpatientswith hemodynamic instability [16] In addition, presence of severe hypoxemia and metabolic acidosis were associated with NIPPV failure While none of the patients who succeeded ... reported that delaying intubation in non-invasively ventilated patientswith Pneumocystis pneumonia is associated with increased mortality Among patients who failed NIPPV in the present study, ... Hemodynamic instability and shock are major contraindications to non-invasive ventilation inpatientswith ALI • Metabolic acidosis and severe hypoxemia are associated withfailureof non-invasive...
... duration of response to the initial treatmentOf the 42 patients, 10 had to be retreated within 12 weeks after discontinuation of infliximab infusions, 37 within 24 weeks, and 38 within 36 weeks ... are lacking) Another finding of our study is that discontinuation of infliximab therapy seems justified, since we found that retreatment with infliximab was safe, resulting in a good clinical ... therapy with infliximab inpatientswith AS leads to a clinical relapse of the disease, with deterioration of signs and symptoms, after several weeks to months This indicates that the majority of patients...
... radiochemotherapy with vinorelbine plus cisplatin or carboplatin inpatientswith locally advanced non-small-cell lung cancer (NSCLC) and an increased risk oftreatment complications: Preliminary results ... significantly correlated with percentage of lung volume receiving 20 Gy (V20) or 30 Gy (V30), with NTCP and MLD SARP occurred in 45% and 37% ofpatientswith MLD of more than 15 Gy and NTCP of 50% or more, ... occurred in 0% ofpatientswith a MLD of 10 Gy or less and NTCP of less than 17%, respectively In our study, we found the NTCP and MLD were significantly associated with the incidence of SARP...
... cause of death was tumor dependent in 69 patients (73%) Inpatients (4%) the cause of death was another carcinoma and in one patient each (1%) cardiac insufficiency and pulmonary embolism In 19 patients ... regarding the optimal treatmentof the patients, including those with DM, are warranted This study’s aim was to evaluate the longterm treatment outcome at our institution as well as patterns offailure ... therapy shortly after finishing radiation therapy is an effective option for reducing radiation-induced side effects In the question of factors influencing the incidence of DM different variables...
... develops in 20% to 40% of BMT recipients [47] Amphotericin during conditioning Acyclovir during conditioning Vancomycin during conditioning The main site of liver damage in this setting is the ... Darmon et al reported with many anti-cancer agents, including gemcitabine, bleomycin, cisplatin, CCNU, cytosine arabinoside, daunorubicin, deoxycoformycin, 5-FU, azathioprine and interferon α [25] ... and uricolytic treatmentinpatientswith a high risk ofacute TLS, prevention of contrast nephropathy, elimination of nephrotoxic drugs in high-risk patients, and monitoring of serum methotrexate...
... pre-existing lung injury in most patientswith ALI 10 11 12 Key messages • Biological markers of lung injury are elevated in spontaneously ventilating patientswith ALI 13 • Intubation and institution ... acceptance of the null hypothesis, namely that the institution of positive pressure ventilation is not associated with an increase in biomarkers of lung injury The total number ofpatientsin this ... not increase In fact, the level of IL-8 was significantly lower at the later time point Thus, the institution of a low tidal volume strategy inpatientswith ALI may not worsen lung injury in...
... written informed consent Handedness was determined using a Chinese translation of the Edinburgh Handedness Inventory 29 Such an inventory has been used in two previous Chinese studies 30,31 Each of ... in our GAD patients was due to the severity of anxiety itself merits further investigation In our TRD patients, the depression score was correlated negatively with Magnitude This finding is in ... higher than 25 The internal reliability of this inventory is 93 21 Procedures All subjects were requested to bisect eight lines without measuring or folding the paper The lines, drawn in black and...
... (12 of 17) of the formalin-fixed samples, and 38% (10 of 26) of the Bouin's fixed tissues Thus, the VHL gene was entirely sequenced (ie 100% of the coding sequence analysed) for a total of 26 ... ppm.years with peaks) other chlorinated solvents, cutting oils, lead, ionizing radiations, asbestos and welding fumes 20 pack-years < 25 of missense mutations is different in the two groups with 68% of ... support the hypothesis of the involvement of environmental factors in the aetiology of sporadic RCC [17-19] Brüning et al studied the RCC incidence in individuals with former prolonged and high-level...
... incorporates modifications resulting from the findings of this study These studies should include an assessment of whether extending the response options in the Ease of use domain from to points ... (v1.1) In general, how afraid are you of needles? General feelings about injections Feelings about injections In general, how afraid are you of having an injection? How anxious you feel about giving ... (v1.1) In general, how afraid are you of needles? General feelings about injections Feelings about injections In general, how afraid are you of having an injection? How anxious you feel about giving...
... verified by studies performed withpatientswith respiratory failure, with depression being observed in 30% ofpatientswith moderate failure and in 50% inpatientswith severe obstructive pulmonary ... depression [4] In relevant studies in Greece, 28.1% ofpatients hospitalized in general medical or surgical hospital wards had depression [5,6] Inpatientswith pulmonary disease in particular, functionality ... patientswith TB had the lowest depression scores Anxiety was higher inpatientswith COPD compared to patientswith TB Patientswith COPD were older and had more years of illness compared to those with...
... II inhibitors One third of the cohort, 117 patients (29.4%), were taking GCs, with similar numbers in the LE and ME groups (58 versus 59 patients, respectively) Other drugs included statins in ... resulting in a distinct lack of direct evidence to support this relationship In RA, this association has been studied in more detail, with two recent studies demonstrating an increase in blood ... However, there is smaller bank of conflicting data demonstrating that GC use in RA paradoxically restores glucose handling to normal whilst also inducing hyperinsulinism [68] In the present RA population,...
... role in the treatmentof inflammatory arthritis Prior studies utilizing IFN-β (Rebif®) for the treatmentof collagen-induced arthritis in rhesus monkeys suggested clinical improvement in 75% of ... of adverse events between placebo and activeβ drug arms of a trial of interferon-β-1a inpatientswith rheumatoid arthritisa Response, according to ACR criteria, of subjects in a trial of β interferon-β-1a ... effects of IFN-β1a in the treatmentof RA The decision to consider the use of this therapy in RA was predicated on the wellknown safety profile of the agent when used in the treatmentof multiple...
... Cystadenocarcinoma of the appendix: an incidental imaging finding in a patient with adenocarcinomas of the ascending and the sigmoid colon BMC Gastroenterol 2003, 3:30 Lyda MH, Noffsinger A, Belli ... protocols of tissue section and methods of histopathological examination may lead to differences in the incidence percentages The unexpected finding in the present study was that one percent of CRC patients ... http://www.wjso.com/content/7/1/51 from routine interval appendectomy in 210 patientswith intraabdominal malignancy; accounting for 0.95% One case was secondary to a sigmoid cancer with limited peritoneal carcinomatosis while...
... expression of ICOS in these patientswith SLE We examined expression of ICOS in three patientswith active SLE before and after treatmentwith highdose prednisolone In these three cases, percentages of ... were receiving maintenance doses of corticosteroid whereas 13 out of the 16 patientswith active SLE considered in the analysis of ICOS expression were examined before institution of any treatments ... median 0) Sixteen of the 22 patientswith active SLE were examined before administration of corticosteroids and immunosuppressants Treatments for the remaining six patientswith active SLE were...
... reduction in mobility achieved with the use respiratory gating, derived from calculating the displacement of the GTVgating within GTVall phases, and (iii) residual GTV mobility within gating windows, ... displacement of the GTVsingle phase within GTVgating Treatment planning and dosimetric analysis Treatment planning was performed on each PTVroutine, PTVall phasesand PTVgating, all of which were ... efficiency oftreatment delivery, and a total of phases were selected inpatients as review of the 4DCT movies suggested limited mobility of the primary tumor within in these 'gates' Deriving target...
... proteolytic domain Caspase 8L binds to the Fas-associating protein with death domain (FADD) and blocks the binding of caspase to FADD by competiive inhibition [39] Indeed, in hematopoietic stem cells ... reduction of adhesive properties of CPCs One could logically consider the in vitro binding of CPCs to fibronectin as a reflection of the capacity of CPCs to bind to damaged endothelium in vivo ... no competing interests Authors' contributions JM was in charge of most of the experimental work, data analysis and drafting of the manuscript KL was in charge of the recruitment ofpatients and...