treated ra patients and correlation with the treatment response

Báo cáo y học: "Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-α, Oncostatin M and response to biologic therapies" ppt

Ngày tải lên : 09/08/2014, 14:22

... these patients maintained this response to 12 months post therapy The change in IL-17A levels pre/post biologic therapy strongly correlated with the change in CRP (r2 = 0.817, P < 0.01) and the ... biologic agents Patients who had previously received biologic therapy were excluded from the study Changes in conventional therapy were permitted during biologic therapy at the discretion of the patient's ... in the study All 38 patients began biologic therapy after their baseline assessment of disease activity Patients were evaluated before and at 1, and 12 months after initiation of biologic therapy...

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Báo cáo khoa học: "Expression of the metalloproteases MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TIMP-1 and TIMP-2 in angiocentric midfacial lymphomas" potx

Ngày tải lên : 09/08/2014, 07:22

... localized in the nasal cavity, in four patients it was localized in the palate and in three in the nasopharynx (Fig 1) In 12 patients the treatment was chemotherapy followed by radiotherapy; four patients ... carcinomas and non-Hodgkin's lymphomas and reactive lymphocytes and peritumoral stroma [19-22] In cancer, in spite of the classical proteolysis of the basal membrane and the extracellular matrix, the ... pathological parameters included, besides status and survival of the patients From all the studied cases, two of them were analyzed ultrastructurally, showed prominence of endothelial cells and infiltration...

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Báo cáo y học: " Blood product ratio in acute traumatic coagulopathy - effect on mortality in a Scandinavian level 1 trauma centre" pptx

Ngày tải lên : 13/08/2014, 23:20

... period and 156 from the 2005-7 period (Table 1) The excluded Table Demography and admission hematology and coagulopathy in the 253 trauma patients included in the study from the 2001-3 and 2005-7 ... of the administration of FFP and PLT, as patients receiving early FFP and PLT therapy displayed improved survival [18] In the present study, administration of FFP and PLT commenced within the ... of the present study was that a change in transfusion therapy with more aggressive and early administration of plasma and platelets in relation to RBC did not influence survival in the trauma patients...

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Tiết 1: Cổng trường mở ra

Ngày tải lên : 27/06/2013, 11:45

... chẽ với ? Với em, viết xong văn có em 4/ Kiểm tra văn kiểm tra lại không? Vậy ta phải làm gì? HS:- TL: ? để tạo lập đợc văn em phải làm gì? Kiểm tra khâu cuối cùng, quan trọng Vì xây dựng bố cục ... Cuộc chia tay nhà HS đọc thích giải nghĩa số từ khó theo mục 3/ Gii thich t khú thích ? Truyện viết , việc ? nhân vật chính? ? Truyện đợc kể theo thứ ? việc chọn kể có tác dụng ? Thể đợc suy ... Đối thoại linh hoạt - Kể xen miêu tả biểu cảm ? Theo em , từ câu truyện đau sót cảm động 3/ Bài học rút từ câu truyện rút học ? GV cho HS thảo luận theo nhóm phát biểu : - vai trò quan trọng GĐ...

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Bài: Sử dụng chung 1 máy in

Ngày tải lên : 08/07/2013, 01:26

... Printers and Faxes chọn Add a Printer Trong Welcome to the Add Printer Wizard chọn Next Trong Local or Network Printer Network Printer chọn A network printer or a printer attached to another computer ... Next để tiếp tục Trong Completing the Add Printer Wizard nhấn Finish để hoàn tất Sau máy in cài đặt xong có biểu tượng (Icon) tên máy in mạng nằm Printers and Faxes Từ máy mạng in tài liệu trực...

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giao an toan tuan 1-18 IN ROI

Ngày tải lên : 17/08/2013, 13:10

... đề Cho HS làm theo nhóm Gọi HS nêu kết GV Nhận xét kết luận Giáo án lớp HOẠT ĐỘNG CỦA HỌC SINH HS lên bảng 99 578 < 100 000 HS giải thích theo nhiều cách khác Nêu ý kiến Chú ý theo dõi Nghe ... giá trò chữ số theo hàng lớp II ĐỒ DÙNG DẠY HỌC: - GV: bảng phụ, lược dồ SGK phóng to - HS : nháp III CÁC HOẠT ĐỘNG DẠY VÀ HỌC CHỦ YẾU: Ổn đònh tổ chức: Hát Kiểm tra cũ: GV kiểm tra Bài tập hs ... tổ chức: Hát Kiểm tra cũ: GV gọi HS làm 3,4 tiết trước GV nhận xét cũ, ghi điểm cho HS Bài mới: HOẠT ĐỘNG CỦA GIÁO VIÊN Hoạt động 1: Làm quen với biểu đồ tranh Mục tiêu : tranh HOẠT ĐỘNG CỦA...

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Tiết 1- Cổng trường mở ra

Ngày tải lên : 15/09/2013, 07:10

... trường mở ra Ho¹t ®éng : Hướng dẫn đọc hiểu nội dung ý nghĩa cđa v¨n b¶n G H·y ®äc phÇn chó thÝch SGK sau ®ã tr×nh bµy nh÷ng nÐt s¬ lỵc vỊ t¸c gi¶ vµ xt xø cđa t¸c phÈm HS: Tr¶ lêi theo néi ... cđa ngêi mĐ ®ªm tríc ngµy khai trêng cđa G C¨n cø vµo nh÷ng ®iỊu võa t×m hiĨu chung vỊ v¨n b¶n , theo nªn ®äc v¨n b¶n nµy nh thÕ nµo ? V× sao? HS : Nªu çch ®äc : Giäng chËm r·i; t×nh c¶m GV híng ... lßng ngêi mĐ T©m tr¹ng ®Đp ®Ï Êy ®ỵc t¸c gi¶ diƠn t¶ mét çch nhĐ nhµng, tinh tÕ mµ thÊm thÝa G Theo dâi nh÷ng viƯc lµm vµ suy nghÜ cđa ngêi mĐ vµo çi ®ªm tríc ngµy khai trêng ®Çu tiªn cđa con,...

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Học vần lớp 1- Vần in- un

Ngày tải lên : 10/10/2013, 03:11

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Đề đáp án KT 1 tiết Đs Lần 3 st

Ngày tải lên : 20/10/2013, 14:11

... ĐÁP ÁN Câu 1: Theo quy tắc cộng ta có: 20 + 15 +10 = 45 (Cách chọn sách) Câu 2: Để lập đội từ tổ ta chọn người ... chọn người từ tổ thứ Có 10 cách chọn người từ tổ thứ hai Có 10 cách chọn người từ tổ thứ ba Từ theo quy tắc nhân ta có: 10.10.10 = 1000 (cách chọn) Câu 3: Sắp xếp bạn vào hàng có ghế hoán vị...

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Tài liệu Chapter 1 - Living in a Network Centric World CCNA Exploration 4.0 pptx

Ngày tải lên : 12/12/2013, 14:15

... of the pathway between the sender and the recipient – The number of times the message has to change form – The number of times the message has to be redirected or readressed – The number of other ... Architecture • The fact that the Internet is able to expand at the rate that it is, without seriously impacting the performance experienced by individual users, is a function of the design of the protocols ... interfere with network communication are related to the nature of the message itself Internal factors affecting the successful communication across the network include: – The size of the message – The...

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Tài liệu The Insider’s Guide to PR: Chapter 1 WORKING IN A PR CONSULTANCY doc

Ngày tải lên : 13/12/2013, 04:15

... to establish the client objectives in order to develop the right strategy Measurement and evaluation is then carried out once the programme is completed in order to help a client and consultancy ... The Insider’s Guide to PR: Chapter • Evaluation – PR consultancies, similar to other marketing disciplines, need to prove the value of their work, and in so doing, justify their fees! They ... and clients The very nature of in-house PR, on the other hand, makes it sector specific and offers little room for manoeuvre For this reason, many PR professionals move in-house later on in their...

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Tài liệu Báo cáo khoa học: Lipopolysaccharide-evoked activation of p38 and JNK leads to an increase in ICAM-1 expression in Schwann cells of sciatic nerves ppt

Ngày tải lên : 18/02/2014, 18:20

... the presence of cytokines Natural ligands of ICAM- 1and LFA-1 are expressed on the surface of T and B lymphocytes, natural killer cells, monocytes, macrophages and granulocytes [33], and interaction ... supported by the National Natural Scientiﬁc Foundation of China (grants 30300099 and 30770488), the Natural Scientiﬁc Foundation of Jiangsu Province (grants BK2003035 and BK2006547), the College and University ... phosphorylated ERK, p38 and JNK (p-ERK, p-p38 and p-JNK) and total ERK, p38 and JNK (tERK, tp38 and tJNK) (B) The ratio of phosphorylated to total ERK (p44 ⁄ 42), p38 and JNK at each time point The data are...

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Tài liệu Báo cáo khoa học: Role of transcription factor activator protein 1 (AP1) in epidermal growth factor-mediated protection against apoptosis induced by a DNA-damaging agent doc

Ngày tải lên : 19/02/2014, 06:20

... autoradiography Arrowheads indicate the positions of the supershifted bands (C) Cells were treated with PD98059 and then with EGF for the indicated times Nuclear extracts were prepared from the ... in the AP1 binding to DNA (A) Cells were pretreated with PD98059 (50 lM) for 90 and thereafter treated with EGF for the indicated periods Nuclear extracts of the cells were then prepared and ... Cells were treated with PD98059 and then with EGF for the indicated times, after which northern blot analysis of Bcl-XL mRNA was carried out The lower panel shows 18S and 28S rRNA to demonstrate equal...

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Tài liệu Báo cáo khoa học: Association of feather colour with constitutively active melanocortin 1 receptors in chicken docx

Ngày tải lên : 21/02/2014, 00:20

... the repeats and the internal order between the three clones was not always the same Therefore, we not draw the conclusion that the cAMP levels for the eb, E and ER cMC1 receptors transfected cells ... for the ewh and ey males and grey for the e+ and eb In melanic alleles (E, ER, and ERfayoumi), adult males are black in all areas and the ﬂight feathers are also black for E, while the other ... increased for the cells transfected with the three clones in all experimental points, as compared with nontransfected HEK-293 EBNA cells, that were used as a control The cells transfected with the receptors...

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mobile mini robots for engineering, Vol.6, No.1 Published in Australia© 2002 pdf

Ngày tải lên : 05/03/2014, 15:20

... framegrabber for the monitoring cameras A WWW-server that interfaces with clients and handles over the Internet the transfer of sensor data from the operator workplace and commands to the rover The ... control and teleoperation aspects of the Mars rover MIDD [2] The MIDD is also participating in the educational Red Rover project of the Planetary Society and the Utah State University [7] The testbed ... Design and programming of a first simple control Calibration of sensors and actuators Conception of performance tests and their documentation Adaptation and fine-tuning of the sensor and control...

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Báo cáo khoa học: High negative charge-to-size ratio in polyphosphates and heparin regulates factor VII-activating protease pdf

Ngày tải lên : 07/03/2014, 02:20

... that the EC50 was 95 ± nm for the shift with unfractionated heparin and 28 ± nm for PolyP65 (Fig 1B and Figs S1 and S2) To examine whether the various polyanions use the same region in the FSAP ... (TBE with sucrose and bromphenol blue) was added, and samples were loaded onto the gel After separation, the gel was stained either with toluidine blue to visualize polyanions (not shown) or with ... This is rather related to the proximity and activation state of mast cells that secrete heparin, such as in atherosclerotic plaques [26] Polyphosphate Heparin and other glycosaminoglycans The binding...

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Báo cáo Y học: Solution structure of the Alzheimer amyloid b-peptide (1–42) in an apolar microenvironment Similarity with a virus fusion domain potx

Ngày tải lên : 08/03/2014, 09:20

... exhausted resin, the solvent was concentrated in vacuo and the residue triturated with ether The crude peptide was puriﬁed by high performance liquid chromatography using a Polymer Laboratories PLRP-S ... complete for the backbone) NOE cross peaks (d2-HFIP/H2O and d2-HFIP/D2O spectra) were integrated with NMRView and were converted into upper distance bounds with the routine CALIBA of the program package ... 1.0-mm path length Spectra were collected over the wavelength range 260–190 nm with a bandwidth of 2.0 nm and a time constant of 8.0 s, and corrected for the contribution of the buffer In order to...

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Báo cáo khoa học: Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1⁄TSC2 in C2C12 myotubes pptx

Ngày tải lên : 15/03/2014, 11:20

... were fractionated into the membrane and cytosolic fractions by ultracentrifugation Pan-cadherin antibody was used as the membrane fraction control, and S6K1 was used as the cytosolic fraction ... from the membrane to the cytosolic fraction On the basis of these ﬁndings, we examined whether or not IGF-1 stimulation caused a redistribution of TSC1 and ⁄ or TSC2 from the membrane to the cytosol ... onto the gel Pan-cadherin antibody was used for the membrane fraction control, and S6K1 was used as cytosolic fraction control (B–D) Distributions of TSC1 and TSC2 proteins in the membrane fraction...

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Báo cáo khoa học: Glycogen synthase kinase 3b and b-catenin pathway is involved in toll-like receptor 4-mediated NADPH oxidase 1 expression in macrophages ppt

Ngày tải lên : 22/03/2014, 21:21

... released into the cytosol and is not degraded by the proteosome, it may be translocated to the nucleus and form a complex with T-cell factor The b-catenin ⁄ T-cell factor complex acts as a transcriptional ... for 40 and stained with anti-b-catenin and DAPI at room temperature for 10 The cells were washed three times with NaCl ⁄ Pi The images were acquired and analyzed using ﬂuorescent microscopy The ... accumulation of b-catenin and translocation to the nucleus by LPS decreased more than in cells transfected with only the vector (Fig 4D–F) Taken together, these results demonstrate that GSK3b plays...

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MEMORANDUM D17-1-10: In Brief potx

Ngày tải lên : 23/03/2014, 03:20

... B3 Show the name and telephone number of the person making the declaration, and identify the company represented by the person making the declaration Date and sign the declaration on the original ... X characters, e.g., ( 3) up to characters (x) = x mandatory characters, e.g., (3) mandatory characters xr = x characters to the right of the decimal point These characters are included in the ... Order, refer to the Memoranda D16 series For provisional, anti-dumping and/ or countervailing duty refer to the Memoranda D14 and D15 series Show the amount in dollars and cents separated by a decimal...

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