transactions and can we get by without them
Báo cáo y học: "Radiographic joint damage in rheumatoid arthritis is associated with differences in cartilage turnover and can be predicted by serum biomarkers: an evaluation from 1 to 4 years after diagnosis" pot
Ngày tải lên :
09/08/2014, 07:20
... coefficients of variance for each biomarker were, respectively: for C2C, 10– 17% and 14%; for C1,2C, 5–14% and 13%; for CS846epitope, 4–12% and 12%; and for CPII, 11–18% and 16% The interassay coefficients ... space narrowing and the erosion scores of both hands and feet, ranging between and 448 (a higher score indicating more damage) Because combinations of markers measuring the balance between different ... ratio, and (C1,2C/C2C)/CPII ratio Biomarker analyses Four biomarkers were evaluated — namely C1,2C, C2C, CS846-epitope, and CPII All assays are described and were used as recommended by the manufacturer...
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Báo cáo y học: "Granulocyte-CSF induced inflammation-associated cardiac thrombosis in iron loading mouse heart and can be attenuated by statin therapy" pptx
Ngày tải lên :
10/08/2014, 05:21
... mice were injected (ip) with 10 mg/kg bw simvastatin (USP, Laucala Campus Suva, Fiji Islands) for first two weeks (days 1st, 3rd, and 5th/week) in addition to four weeks of I+G treatment Mice were ... Briefly, mAbs and cells were incubated for 30 minutes at 4°C and unbound reagents were removed by washing Cells were then resuspended in fixing buffer (PBS containing 1%formaldehyde and 1% FBS) ... determined by BCA™ protein assay reagent Western Blot chemiluminescence reagents were obtained from PIERCE (Pierce Chemical Co.) Proteins were separated by polyacrylamide gel electrophoresis and transferred...
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báo cáo khoa học: " Can we prevent drug related deaths by training opioid users to recognise and manage overdoses?" doc
Ngày tải lên :
11/08/2014, 18:20
... word of mouth and needle exchange services Participants were followed up and reinterviewed three months and six months after the training event, if they were available Interviews were performed ... significantly elevated - approximately 2-3% of heroin users die each year and these rates are between six and twenty times higher than those expected among non-drug using peers of the same age and ... is a significant cause of mortality for injecting drug users (IDUs) Between 1997 and 2002, opiates (including heroin, morphine and methadone) accounted for 6,194 deaths in England and Wales [1]...
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Báo cáo y học: "Hemodynamic changes during weaning: can we assess and predict cardiac-related weaning failure by transthoracic echocardiography" doc
Ngày tải lên :
13/08/2014, 21:20
... doi:10.1186/cc9085 Cite this article as: Voga G: Hemodynamic changes during weaning: can we assess and predict cardiac-related weaning failure by transthoracic echocardiography? Critical Care 2010, 14:174 ... change during weaning [8] Concerning the results of the study, two clinically important questions should be answered First, should we routinely use TTE in patients before weaning? If we take into ... used before SBT for hemodynamic assessment and estimation of the risk of cardiac-related weaning problems The second question is whether we can detect and monitor the hemodynamic changes during...
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Báo cáo y học: "Translational Medicine and Reliability of Single-Nucleotide Polymorphism Studies: Can We Believe in SNP Reports or Not"
Ngày tải lên :
25/10/2012, 10:51
... when we investigated this theory by comparing the IF from journals published positive studies versus those published negative we found no significant association between IF and positive studies We ... association between at least of one GST SNP: and cancer outcome; and (b) include only patients with solid tumours We excluded case-control studies that examined the role of GST polymorphisms on cancer ... studies were identified from the combined searches We scanned titles and abstracts for mention of GST polymorphisms associated with cancer outcome in either the title or the abstract We retrieved...
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How Our Actions Create our reality ... and how we can change it
Ngày tải lên :
17/10/2013, 18:20
... our offices, and we said 'How are we going to handle this? We' ll tell everybody to send in a $5,000 check with their name and we' ll put them on the list.' The next thing we knew, we had over 150 ... understand," says the retailer "The demand never mushroomed And it never died out We still sell eight cases of beer—week after week after week But you didn't send us the beer we wanted So we had ... consumer demand, and even the retailers saw demand only week by week, with no clue about what would come next After the beer game, we ask the people who played wholesalers and brewers to draw...
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What is the neutral real interest rate, and how can we use it? doc
Ngày tải lên :
15/03/2014, 01:20
... actual interest rate differentials between New Zealand and Australia and New Zealand and the United States the 1990s Given the new structure of the economy, new We not explicitly allow for the possibility ... NRR cited by economic commentators in and the United States and adjusts these for New Zealand- the United States generally range between 2.0 and 2.75 per specific risk factors.14 As we have noted ... In this article we expand on the above distinction and clarify between actual and potential output is known as the “output alternative concepts of the neutral real interest rate We gap” If actual...
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Báo cáo khoa học: Caspase-2 is resistant to inhibition by inhibitor of apoptosis proteins (IAPs) and can activate caspase-7 pot
Ngày tải lên :
23/03/2014, 13:20
... that triggered by either caspase alone (compare lane 12 with lanes and 11) Much weaker synergy was also reproducibly observed between caspase-2 and -3 (compare lane with lanes and 5) We then tested ... growth and viability Yeast cells were transformed with the indicated plasmids Suspensions of each transformant were prepared at standardized concentrations Serial dilutions were made and spotted ... or D330 residues were generated and expressed in bacteria and the protein purified (Figs and 6A) 1406 We observed that full length recombinant caspase-2 has about a 10-fold lower activity than...
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Unequal, Unfair, Ineffective and Inefficient Gender Inequity in Health: Why it exists and how we can change it pptx
Ngày tải lên :
28/03/2014, 12:20
... bearing and raising children, and on culture by weakening the links between sexuality and child-bearing, and by transforming the size, composition, and relationships within families (Presser and ... subordinate, and hierarchise people, and particularly though not only in the case of transgender and intersex people, marginalise and exclude them 10 Women have less land, wealth and property ... equality and for people’s life and well-being, as patients in both formal and informal health care, paid and unpaid care providers, health care administrators and decision makers However, health...
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sexual selections what we can and can’t learn about sex from animals
Ngày tải lên :
01/06/2014, 10:54
... in which we lose interest We can appreciate dolphins without making them into animal Einsteins, and we can use them in our ongoing struggle to understand intelligence without making them rank ... this connection, and we create a hierarchy of what should be loved and preserved in nature that can deflect our attention from “lower” species worthy of study in their own right, and can also backfire ... out, we interpret what we see in terms of “gender schema,” ideas about what the sexes are like, physically, mentally, and emotionally If men are generally viewed as tall, we see them as tall, and...
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báo cáo hóa học: " Can we derive an ''''exchange rate'''' between descriptive and preference-based outcome measures for stroke? Results from the transfer to utility (TTU) technique" doc
Ngày tải lên :
18/06/2014, 18:20
... which we can predict an individual's AQoL score We calculated MADs by taking the absolute difference between predicted and observed scores for each individual, summing over all individuals, and ... or random effects frequently fail to provide unambiguous guidance; and concludes that the choice between fixed and random effects should instead be driven by the data Specifically, the random ... correlation between predicted QALYweights from the Brazier [36], Fryback [7] and Nichol [33] algorithms but a sometimes modest correlation between predicted and observed QALY-weights Kaplan et...
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Top producers today realize they can no longer get by on product expertise alone. pot
Ngày tải lên :
28/06/2014, 12:20
... these lessons can help you assess yourself, spot your strengths and weaknesses, and change your sales talk You will tap into your natural skills, leverage your knowledge, and sell more by creating ... spouting formulas as if we know what to with them! ” They were asked to respond with empathy They said, “What is it you don’t understand?” and “I’ll go over the process again” and so on No one initially ... long,” may be satisfied with “Because we tailor the packaging.” However, you can be the salesperson who connects better and closes more sales by saying, “Two months can seem long May I ask what your...
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Báo cáo sinh học : "What do we know about influenza and what can we do about it" ppsx
Ngày tải lên :
06/08/2014, 19:20
... interfere with viral replication; and we have already mentioned the HA and the NA, and members of the viral polymerase complex Apart from their effects on viral infectivity and replicative capacity, ... H5N1 viruses were so virulent that they killed chick embryos before much virus was made, and new recombinant vaccine viruses had to be made by inserting the H5 and N1 into one of the standard vaccine ... strategies and vaccine formulations for epidemic and pandemic influenza control Hum Vaccin 2009, 5: 126-135 Sui J, Hwang WC, Perez S, Wei G, Aird D, Chen LM, Santelli E, Stec B, Cadwell G, Ali...
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Báo cáo lâm nghiệp: "Can we reconstruct deer browsing history and how? Lessons from Gaultheria shallon Pursh" pdf
Ngày tải lên :
08/08/2014, 00:21
... deer-free islands (Lost, Low and Tar Islands) and from all four of the deer-affected islands (Reef Island, Ramsay Island, Burnaby Island and south of Moresby Island) The latter were roughly distributed ... Island and Tar Island) and deer-affected islands (Reef Island, Ramsay Island, Burnaby Island and the south of Moresby Island) (Fig 1) On each island we selected sites that had sufficient representation ... (Reef Island), intermediate (Ramsay and Burnaby Islands) and southern (southern Moresby Island) deer-affected islands using the “least significant difference” (l.s.d.) post-hoc test We compared...
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báo cáo khoa học: "Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways" doc
Ngày tải lên :
10/08/2014, 22:20
... methylation status of p15 and p16 genes were not significantly different between MM and MGUS (monoclonal gammopathy of unknown significance) nor in pre-treated and post-treated patients with MM [6-8] ... inhibitor of HDACs [29,30] We have found that PHI can induce selective histone acetylation and lead to cell cycle arrest and apoptosis in human leukemia cells and prostate cancer cells [29-31] Oral ... expression level of IL-6 receptor subunits, gp80 and gp130, as well as p21 protein were determined by Western blot analysis as described in Material and Methods β-actin level in the same blot was...
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báo cáo khoa học: " Prostate cancer genomics: can we distinguish between indolent and fatal disease using genetic markers?" docx
Ngày tải lên :
11/08/2014, 12:20
... in Icelandic families with prostate cancer, followed up by association analysis in three independent case-control populations [9], and separately through admixture mapping in African Americans ... prostate cancer who were of European descent and who underwent radical prostatectomy for treatment of prostate cancer [47] Based on the entire prostate gland, each tumor was uniformly graded and staged ... diagnosed between 2001 and 2003 were followed up for prostate cancer mortality through January 2008 Overall, 626 (21%) of the patients died during follow-up and of those 440 (15%) had prostate cancer...
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Báo cáo khoa học: " Blood management in intensive care medicine: CRIT and ABC — what can we learn" docx
Ngày tải lên :
12/08/2014, 20:20
... scores and Acute Physiological and Chronic Health Evaluation II scores, and were more frequently in shock at hospital admission [2] This potential confounding can only be avoided in prospective, randomized ... patients were sicker to start with Indeed, there is some evidence that this was the case In the ABC study transfused patients were older, had a lower baseline hemoglobin, had higher Sepsis-related and ... age and in patients with an Acute Physiological and Chronic Health Evaluation II score
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Báo cáo y học: "Percutaneous dilatation tracheostomy: which technique is the best for the critically ill patient, and how can we gather further scientific evidence" pptx
Ngày tải lên :
12/08/2014, 20:20
... community and fostering progress in the field The work by Fikkers and coworkers raises some interesting questions regarding percutaneous dilatation tracheostomy in the intensive care setting, and these ... V, Rinne T, Westphal K: Bedside percutaneous tracheostomy: clinical comparison of Griggs and Fantoni techniques World J Surg 2001, 25:296-301 Byhahn C, Wilke HJ, Halbig S, Lischke V, Westphal K: ... 91:882-886 Westphal K, Byhahn C, Wilke HJ, Lischke V: Percutaneous tracheostomy: a clinical comparison of dilatational (Ciaglia) and translaryngeal (Fantoni) techniques Anesth Analg 1999, 89:938-943 Byhahn...
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Báo cáo y học: " Gingival and plaque decontamination: Can we take a bite out of VAP" potx
Ngày tải lên :
13/08/2014, 01:20
... address a number of outstanding questions and issues related to oral hygiene and VAP prevention The development of simple and reproducible methods and tools to assess and define the state of dentition, ... is applied directly to dental and gingival surfaces, may reduce the frequency of VAP and ICU-acquired bacteremia [6] In this randomized controlled trial by Fourrier and colleagues [1], PAD with ... anticipated, the study was underpowered Two-thirds of the subjects were considered infected at the time of ICU admission (primarily bronchitis and communityacquired pneumonia) and prior antibiotic usage...
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