... upon (v): ập xuống bất ngờ, đến bất ngờ greed (n): tính tham lam 10 to bring S.O to justice: đem tòa, truy tố trước tòa 11 on the move: di chuyển 12 facility (n): điều kiện thuận lợi, phương tiện...
... between the sub-domains andthe domains and between the domains andthe total score at baseline, at endpoint after the placebo-controlled period, and for the change from baseline to that endpoint ... Item-domain correlations Within the various CHIP-CE domains, the highest andthe lowest Spearman’s correlations between the individual items andthe respective domain are reported inthe following The ... data from clinical trials studying atomoxetine and using the CHIP-CE inthe Lilly data base were included The total number of patients included inthe combined analysis was 794 Three of these studies...
... of lifeInthe face of impaired physical and mental functioning, perceived social handicap stands inthe way of realizing quality of life Success in improving physical and social functioning and ... subjective wellbeing e.g mental health and quality of life (healthy ageing) Multi-disciplinary collaboration of research aimed at understanding the ageing and health transition of Singaporean older ... Methodology: Data from the baseline survey of participants inthe Singapore Longitudinal Ageing Studies (SLAS) Thesis: The present trend of functional disability is increasing It should be reversed...
... was further investigated by determining thein uence on the glycone binding of the Sfbgly interactions with the aglycone Thus, the effect of the alteration of the glycone structure inthe stability ... E190 and E194 are positioned in an internal region of the aglycone-binding site, probably subsite +1, because they in uence the binding of the first glucose unit of the aglycone On the other hand, ... details about the role of different residues of the aglycone-binding site inthe stabilization of ESà andthe interdependence between the binding of aglycone andthe positioning of glycone in subsite...
... him gathering in his crops and handing over the white farmer's share of the crop to the owner of the land; watch the farmer receiving his tribute from the native tenants, and see him deliver the ... South Africa, inthe interests of the Natives, andinthe interests of just legislation let the Government withdraw the Bill, and appoint a Commission, and then justice and not injustice would ... allow them to go on their own lines was merely to drive them back into barbarism; their own lines meant barbarous lines; their own lines were cruel lines All along they had been bringing them...
... siblings born alive to the sample individuals’ mothers andthe number of siblings alive at the time of the interview Figure presents the distribution of the number of siblings estimated from the ... current and past smoking and drinking status, and own- and spouse’s living experience inthe United States as well as the number of years worked Since the survey-based data measure not actual incidence ... have addressed the specific question of how the number of sibling is related to health outcomes in later lifeIn this paper, I link these two strands of the literature and examine the relationship...
... subsite Substrate binding induces conformational changes involving the ArgA145PheA146 fragment of the protein chain, acting as a flap, first opening and then closing the groove [45] The catalytic reaction ... ArgA145 and ArgB263, on the negatively charged COO– inthe aminic part determines the position of the substrate within the S1¢-binding subsite O atoms of the main chain CO groups of LeuB387 and TrpB240, ... of the side chain d-guanidino group of this residue are involved in H-bonding as follows: Ne with the O atom of the main chain CO group of the TrpB240; Ng1 shares H bonding with O atom of the...
... may in uence the shape and volume of the acyl binding pocket and thereby alter the binding mode and affinity of the enzyme for PAA and derivatives thereof, while maintaining the hydrophobicity ... using ½I ð3Þ Kmapp ¼ Km Á þ Ki in which Kmapp is the Km for NIPAB inthe presence of inhibitor, [I] the inhibitor concentration, and Ki the inhibition constant or binding constant for the ... that the binding of both the substrate NIPAB andthe product PAA are significantly altered by mutating the phenylalanines inthe active site suggesting that hydrophobic interactions between the...
... weakening of social infrastructure along the lines seen inthe UK and US and to a lesser extent in Canada 9.1 Decline of the welfare state Teeple [11] sees increasing income and wealth inequalities ... Financing comes from a mix of fees and tax financing In some provinces, these fees are very low, in others, higher [78] Differences exist among provinces in integration of long-term care with the ... on reducing taxes—directly benefits the wealthy and powerful and translates into both increasing economic inequality andthe weakening of communal institutions that support women [40] Nonetheless,...
... to the species by suffering, such as pain, hunger, thirst, and fear; or by pleasure, as in eating and drinking, andinthe propagation of the species, &c.; or by both means combined, as inthe ... by the citation of a few sentences.[1] In certain periods of my father's lifethe scientific andthe personal elements run a parallel course, rising and falling together in their degree of interest ... stood inthe drawing-room I think he sometimes fused together his admiration of the structure of a flower and of its intrinsic beauty; for instance, inthe case of the big pendulous pink and white...
... Arranging the plugs and setting the switches in a certain way causes the machine to act in accordance with the instructions in Table Other ways of setting up the ‘switchboard’ cause the machine ... of determining whether each description number is satisfactory or not 12 The Printing and Halting Problems The printing problem Some Turing-machine programmes print ‘0’ at some stage in their computation; ... the halting and printing problems, and moreover in a Wnite time See B J Copeland, ‘Super Turing-Machines’, Complexity, (1998), 30–2, and ‘Accelerating Turing Machines’, Minds and Machines, 12...
... cut-off-point: 70.1 SE: 0.73 SP: 0.70 the case of the KINDL-R questionnaire [14] The VSP-A was developed using exclusively the opinion of adolescents for defining item and domain content [13] The final ... scores inthe Spanish sample The use of both instruments in different populations, including clinical samples and from different geographical areas in Spain will allow for continuing the validation ... friends/friends in both HRQL questionnaires were compared to the Oslo Social Support Scale Inthe case of the anchor measuring physical chronic conditions, it was compared with domains inthe VSP-A and KINDLR...
... collection and collation, data analysis, writing and editing of the manuscript CM was involved inthe conception and design of the study, as well as data analysis and writing and editing of the manuscript ... Perhaps in persons with mild MS, the physical limitations of the disease are minimal and therefore irrespective of exercise status the impact of the disease on QoL inthe physical domain is minimal ... Scale Competing interests The authors declare that they have no competing interests Authors' contributions NS was involved in all aspects of this study She was involved inthe concept and design,...
... allow us to infer causality Cautions should be exercised when interpreting and generalizing the current findings in other populations as the present sample consisted of mainly Chinese female ... the negative effects of pain on physical QoL The indirect effect of depression on the pain-QoL link pathway was 0.08, indicating that about 75% of the effect of pain on QoL impacted through the ... mediated the painQoL link for the physical aspect (Model 4) When pain was the mediator, it accentuated the negative effects of depression on mental functioning The indirect effect of pain on the depression-QoL...
... The challenges are the impact of the condition on daily lifeand functioning, the psychosocial consequences, andthe impact on individual psychological and social well-being [1] There is an intense ... years It was the mother who answered the questionnaire in 92.52% of the sample, and it was the father in 7.48% of the sample No parent inthe patient group refused to participate inthe study, ... more willingly when asked by medical staff On the other hand, patient and parent stress and time limitations could be factors that explain incompleteness of filling -in the questionnaire Inthe postal...
... of the study protocol andthe informed consent document The study was initiated at each site after the principal investigator andthe study sponsor obtained approval documents The principal investigator ... a continuous variable and change inthe VFQ-25 scales, controlling for age, gender, and visual acuity at baseline In all models, except the one with the VFQ-25 ocular pain subscale as the dependent ... obtaining informed consent from each patient or legal representative and for obtaining the appropriate signatures on the informed consent document prior to performing any procedures or administering...
... with IRD andthe planning of the healthcare services should take these findings into account by maintaining the focus on impairment and physical function, but also focusing on the mental and social ... analysis and input into writing the manuscript MC provided radiological support for the study, was involved in designing the study and helped draft the manuscript SG provided clinical support and ... emotional health, social functioning, and vitality The SF36 scores decreased (indicating a linear decline in HRQL), especially inthe physical dimension, with increasing age in all categories of IRD...