... begin in England? Scouting began in England in 19 07 Question 2: What led to the Scouts Association crossing the Atlantic in 19 10? An American businessman, William Boyce got lost in London A boy ... citizenship and personal fitness Scouting began in England in 19 07 Two years later an American businessman, William Boyce, got lost in London A boy helped him and explained that he was a scout ... later an American businessman, William Boyce, got lost in London A boy helped him and explained that he was a scout This meeting led to the Scout Association crossing the Atlantic in 19 10 Although...
... Medicine, William Osler Health Centre, Toronto, Canada Department of Anesthesia, University of California, San Francisco at San Francisco General Hospital, San Francisco California, USA Authors’ ... two reasons First, previous studies have reported an average duration of mechanical ventilation in ALI between and 16 days, suggesting that a large proportion of patients with ALI are alive and ... low oxygenation index and an increased extravascular lung water [3-5] However, important decisions regarding therapeutic interventions and changes in goals of care are often made later in the course...
... times ranging from to 24 hours Thus, Bcl-2 conformational change, Bax activation and up-regulation of total Bax expression involved arsenic trioxide-induced apoptosis rather than affecting total ... substantial experimental and clinical research remains to validate its potential value Conclusion Our results show that arsenic trioxide is an effective anticancer agent with potential for human ... as the mean values ± standard deviation of the mean (SD) Statistical significance of differences between groups was analyzed by using ANOVA analysis P < 0.05 was considered statistically significant...
... Jensen, M .A & Andreasen, P .A (20 01) Epitope mapping for four monoclonal antibodies against human plasminogen activator inhibitor type -1: implications for antibody-mediated PAI -1- neutralization ... M., Vaughan, D.E & Collen, D (19 92) Identification of a conformationally distinct form of plasminogen activator inhibitor -1, acting as a noninhibitory substrate for tissuetype plasminogen activator ... Heegaard, C., Jensen, P.H & Andreasen, P .A (19 91) Type -1 inhibitor of plasminogen activators Distinction between latent, activated and reactive centre-cleaved forms with thermal stability and monoclonal...
... the valency hybrid tetramers As a result, the b chain was found to acquire a noticeable resistance against the acidic autoxidation in a manner of contacting with the a chain, no matter which valency ... tetramer For human HbA, the a and b chains contain 14 1 and 14 6 amino-acid residues, respectively, and a representative set of the successive oxygen-binding constants is given in terms of mmáHg )1 ... without any proton catalysis Such a unique stability of the HbO2 tetramer was found to remain even in the low concentrations of hemoglobin corresponding to appreciable dissociation into a1 b1 or a2 b2...
... and renal epithelial cells are no longer only innocent bystanders but active participants in inflammatory reactions Available online http://arthritis-research.com/content/4/3/220 of autoimmune ... mRNA may therefore contribute to lung damage in WG and other ANCA-associated diseases via direct interaction 10 11 12 13 14 15 16 17 18 19 Acknowledgments 20 The authors wish to thank Ms Huong Becker ... Fauci AS: Wegener’s granulomatosis: an analysis of 15 8 patients Ann Intern Med 19 92, 11 6:488-498 Hoffman GS, Specks U: Antineutrophil cytoplasmatic antibodies Arthritis Rheum 19 98, 41: 15 21- 1537...
... to engineer cartilage, bone, muscle, fat, tendon and neuronal cells; they may serve as cell vehicles for gene therapy; they may enhance engraftment in haematopoietic stem cell transplants; and ... of 10 (page number not for citation purposes) MSC enhance haematopoietic engraftment MSCs are capable of homing to the BM and survive in the long term ( >1 year) [54] In an allogeneic animal model, ... series, with apparently low acute toxicity [57,63] Long- term safety data are needed Scanty and sometimes contradictory AD animal data are available Although the results from syngeneic and autologous...
... cells and their progenitors J Exp Med 19 91, 17 3:507- 510 Williams RO, Marinova-Mutafchieva L, Feldmann M, Maini RN: Evaluation of TNF-alpha and IL -1 blockade in collageninduced arthritis and comparison ... showed a diffuse stromal staining in certain areas and a vascular staining pattern in others For negative controls, the primary antibody was omitted Scale bars = 10 0 μm neg ctrl = negative control ... 6:2337-2342 Pini A, Viti F, Santucci A, Carnemolla B, Zardi L, Neri P, Neri D: Design and use of a phage display library Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted...
... collection and analysis, drafting of the manuscript ML was involved in conception and design of the study, data collection and analysis, drafting of the manuscript OJ was involved in revision and final ... origin This is important in nerve entrapment syndromes involving subclavius muscle and such supraclavicular axillary nerves Axillary nerve has also been used as a landmark for identifying the ... Philadelphia, USA: Lippincoth Williams & Wilkins; 19 99 Fazan VPS, André SA, Adilson LC, Omar ARF: Brachial plexus variations in its formation and main branches Acta Cirurgica Brasileira 2003, 18 (5)...
... pain Antidepressants have anti-inflammatory and analgesic properties Antidepressants with a dual action (inhibiting serotonin and norepinephrine reuptake) have been shown to have Page of analgesic ... anti-inflammatory action Toll-like receptors are proteins thought to mediate innate immunity They play an important role in initiating an inflammatory reaction in response to pathogen proteins ... cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters Neuropsychopharmacology 2006, 31: 212 1- 213 1 10 Cavanagh J, Paterson C, McLean J, Pimlott S, McDonald...
... 5'-CAACACUCGCAAUAUU-3'(sense) 3'-GUUGUGAGCGACGUUAUAA-5'(antisense) α3 domain 5'-AGGUCUUAUGGUGCUGUCAUU-3'(sense) 3'-UUUCCAGAAUACCACGACAGU5'(antisense) Transmembrane domain 5'-UGUGAUGAAUAGGAGGUGAUU-3'(sense) 3'-UUACACUACUUAUCCUCCACU5'(antisense) ... instructions The vector pcDNA3 .1 was transfected into HeLa cells as a control Administration of Qa-2 vector to mice Normal and BD mice were intraperitoneally injected once with 50 ng of pcDNA ... 3'-UUACACUACUUAUCCUCCACU5'(antisense) Cytoplasmic membrane domain 5'-UAGAGCUCUGAUAGAUCUCUU-3'(sense) 3'-UUAUCUCGAGACUAUCUAGAG5'(antisense) France, Illkirchcedex), was intravenously injected into mice...
... a programme embedded in a broader national policy mix involving an increase in managed competition and transparency, a new reimbursement system based on standardised output pricing, and an intensified ... Research 19 97, 32:4 91- 510 Young GJ: Managing organisational transformations: lessons from the Veterans Health Administration California Management Review 2000, 43:66-83 Parry KW: Enhancing adaptability: ... changes) Each QIC served a particular purpose The external change agents translated project targets into measurable indicators, and teams had to deliver monitoring data toa central database In this...
... prospective data findings not report any survival advantages in a patient with pseudomyxoma peritonei syndrome and appendiceal mucinous carcinomatosis undergoing a right hemicolectomy [13 -15 ] In general, ... stranding Both mucinous cystadenomas and cystadenocarcinomas have the potential to cause peritoneal seeding leading to pseudomyxoma peritonei However, survival in patients with a cystadenoma is ... underwent an initial diagnostic laparoscopy to evaluate any mucin spillage or seeding of the peritoneal cavity before surgical intervention, because any such finding could mandate a more extensive...
... molecular var- 10 11 12 13 14 15 16 17 18 19 iation and predicts disease duration J Virol 2002, 76 :11 715 -11 720 Williamson S: Adaptation in the env gene of HIV -1 and evolutionary theories of disease progression ... responses toa recombinant glycoprotein 12 0 vaccine and incidence of HIV -1 infection in a phase HIV -1 preventive vaccine trial J Infect Dis 2005, 19 1:666-677 Pérez-Losada M, Jobes DV, Sinangil ... improvement in accuracy of multiple sequence alignment Nucleic Acids Res 2005, 33: 511 - 518 Korber B: HIV signature and sequence variation analysis In Computational and evolutionary analysis of HIV...
... winner SupT1 winner HIV/AS44 HIV/AS19 HIV/AS15 HIV/AS 11 HIV/AS6 HIV/R1 AS19/R1 HIV (4)b HIV (58) HIV (23) HIV (23) HIV (11 ) HIV (52) AS19/R1 (>62) HIV (4) AS19 (12 ) AS15 (23) AS 11 (33) AS6 (16 ) ... AS15 HIV HIV-lhNef AS44 AS19 AS15AS19 AS 11 HIV HIV- AS44 AS19 AS15 AS 11 lhNef AS 11 AS6 AS6 AS6 R1 B trans-inhibition of HIV -1 CA-p24/RL (%) 360 360 300 300 240 240 18 0 18 0 12 0 12 0 60 60 0 shNef ... resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA Proc Natl Acad Sci USA 19 98, 95 :13 959 -13 964 Adelman ZN, Sanchez-Vargas I, Travanty EA, Carlson...
... that what is really needed is a way to help scientists understand not dogs, but each other Clifford: Now I’m the one who’s not understanding Mink: What I mean is that Greg is always complaining ... gene names and gel slides and acronyms that don’t stand for anything sensible Clifford: Are you saying there should be a computer program that would translate jargon from one field of science ... forgotten something very important He’s forgotten that in the age of genomics, when biology is becoming more quantitative and depending more and more on new techniques and tools that must come from...
... make a significant contribution to the study of signaling pathways that play a very important role in developmental morphogenesis and several human diseases, including cancer 12 13 14 15 16 17 18 ... localization, since nonglycanated glypicans are sorted apically [14 ] Most of the in vivo evidence published so far indicates that the main function of membrane-attached glypicans is to regulate ... role in synapse morphogenesis and function by binding and inhibiting the receptor phosphatase LAR [23] In addition, it has been proposed that glypicans can be involved in the uptake of polyamines...