tissue engineering for the respiratory epithelium is there a future for stem cell therapy in the lung valérie besnard and jeffrey a whitsett

Báo cáo khoa học: "Is there a place for N-acetylcysteine in the treatment of septic shock" pptx

Ngày tải lên : 12/08/2014, 20:20

... microcirculation and thus oxygen extraction, while at the same time attenuating inflammatory responses Prostacyclin, a prostaglandin synthesized in endothelial cells, is a potent vasodilator and an inhibitor ... injury was decreased, however, and there was also a significant increase in the cardiac index in the NAC-treated group [20] Conclusions This is an exciting time for intensivists involved in the care ... TNF-α and IL-6 and reduced the mortality rate in premature infants with sepsis [13] NAC in animal experimental and human sepsis NAC increases nitric oxide synthesis and cGMP Several studies have...

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Báo cáo y học: " Mechanical ventilation in the ICU- is there a gap between the time available and time used for nurse-led weaning?" pot

Ngày tải lên : 13/08/2014, 23:20

... discrepancies between the time used for weaning and time available for weaning and 2) to analyse the patient and systemic factors were associated with the time available for weaning that is actually ... organisational level The aims of this study were to define the time used versus time available for weaning and to study the patient and systemic factors associated with the available time actually ... feedback regarding weaning improvements in an easy and feasible manner can motivate and stimulate further improvements As weaning activity may be fragmented and inconsistent due to the interest and level...

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Development of cell sheet constructs for layer by layer tissue engineering using the blood vessel as an experimental model 1

Ngày tải lên : 14/09/2015, 08:49

... which is to say, they contain three distinct layers (tunicae intima, media and adventitia) and are characterised by the presence of a single elastic lamina and rich smooth muscle cells in the tunica ... for vascular tissue applications As an alternative, decellularised allogeneic or xenogeneic tissues are being studied as potential scaffolds instead Decelluarisation is carried out by lysis and ... Niraja and Darice for the camaraderie, motivation and inspiration I am privileged to have been a part of the GPBE, which has played a large part in the formative years of my scientific training In...

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Development of cell sheet constructs for layer by layer tissue engineering using the blood vessel as an experimental model 2

Ngày tải lên : 14/09/2015, 08:49

... endothelial phenotype 122 Chapter Isolation and Characterisation Of Vascular Progenitors (a) (b) (c) (d) (e) (f) Figure 4-4: CFU assay Adherent colonies appeared after ten days of culture, and ... Chapter Isolation and Characterisation Of Vascular Progenitors Figure 4-3: Primary culture of haemopoietic tissue in EGM Following culture in endothelial cell media, outgrowth colonies ... to have a more heterogeneous phenotype, adopting a more spindle morphology (c) When cultured in the same medium, fibroblastic cells quickly grew out from fetal liver mononuclear cells, and failed...

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Development of cell sheet constructs for layer by layer tissue engineering using the blood vessel as an experimental model 3

Ngày tải lên : 14/09/2015, 08:49

... RhoGEF and PH domain containing FYVE, RhoGEF and PH domain containing GATA binding protein hematopoietically expressed homeobox insulin-like growth factor binding protein interleukin jagged (Alagille ... placental growth factor, vascular endothelial growth factor-related protein pregnancy-associated plasma protein A, pappalysin prostaglandin-endoperoxide synthase (prostaglandin G/H synthase and ... µXPCL Surfaces Using Radio Frequency Glow Discharge (RFGD) Plasma (a) ~ ~ Plasma preacativation Air exposure for 10 mins Spin coat PAAc Plasma induced crosslinking Repeat grafting (b) Pristine 1x...

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Development of cell sheet constructs for layer by layer tissue engineering using the blood vessel as an experimental model 4

Ngày tải lên : 14/09/2015, 08:49

... nonspecific adsorption of proteins In contrast to albumin coatings, which repel all proteins and cells indiscriminately, CD34 antibodies anchor EPC to the surface and facilitate the formation of a stable ... surface leads to the formation of a stable intima capable of maintaining long term haemocompatibility Although my results indicate that contact activation by PCL is low, it was accompanied with an ... vascular tissue engineering, which can be broadly classified under three categories: adhesion proteins, anticoagulants and antibodies I had chosen a candidate from each category, and demonstrated...

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LOOKING for a FIGHT IS THERE A Republican War on Science? potx

Ngày tải lên : 22/03/2014, 23:20

... Republican War on Science, journalist Chris Mooney made the case that, again and again, even overwhelming scientific consensus has met immovable political obstacles And, again and again, those obstacles ... widespread misinformation on the media and public Merely by making it clear that the war against science is taking place, and that the current leadership of the Republican Party is on the wrong ... to any criticism of the Bush Administration is that their opponents, and in particular Clinton’s Democratic Administration, were just as bad Mooney is prepared for this line and sees it off in...

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Is there a silver lining? The Indian mutual fund industry pot

Ngày tải lên : 30/03/2014, 15:20

... to the creation and finalisation of this report Team Members: Anuradha Sanghavi Arun Swaminathan Avinash Kalia H.Sadhak Gautam Mehra Harsh Bisht Jesal Lakdawala Malvika Singh Nehal D Sampat Nidhi ... certification of investment advisors, laying down rules and regulations and enforcing those informing and educating the investing public, setting up and administering a disputes resolution forum for investors ... turn increase compliance costs The related moot question is: does an average investor have the inclination to read and assimilate the flood of information? Should there be an examination of the amount...

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is there a new vision for maghreb economic integration

Ngày tải lên : 22/05/2014, 12:51

... Over the past decade, Tunisia and Morocco have attracted larger FDI inflows, 29 Italy USA Spain Portugal Kuwait France SaudiArabia France Spain Sweden Portugal Italy Germany SaudiArabia Netherlands ... prospects for regional integration is whether there is potential for increased intraregional merchandise trade after accounting for other factors deterring trade, such as market size, geographical and ... costs), tariff barriers, language, culture and other factors that may influence trade patterns Later the chapter expands the analysis of intraregional trade potential in the Maghreb drawing on a panel...

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is there a future for quantum chemistry

Ngày tải lên : 02/06/2014, 09:45

... reactions.(Wikipedia) Chemistry is the science that invents what it studies Theoretical Chemistry Theoretical chemistry is the study of chemistry via fundamental theoretical reasoning, usually ... usually within physics and mathematics ˙ i hψ=Hψ Quantum Mechanics S = k log W Statistical Mechanics Computational Chemistry Computational chemistry is a branch of chemistry that uses principles ... to assist in solving chemical problems Quantum Mechanics Molelcular Orbital Theory Density Functional Theory Ab Initio Calculations Statistical Mechanics Molecular Dynamics Monte Carlo Transition...

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Báo cáo y học: "Is there a dysfunction in the visual system of depressed patients" pptx

Ngày tải lên : 08/08/2014, 21:20

... the light peak is related to the pre-adaptation level of the retina, while the dark trough is stable after only minutes in dark Generally, the standing potential of the eye manifests a diurnal ... include the precise diagnosis according to modern diagnostic criteria and the detailed psychometric assessment The major disadvantage is the deviations from the International Society for Clinical ... M, Iacovides A, Nimatoudis J, Diakogiannis J, Kaprinis G, Demitriadou A, Bech P: Morning and Evening Plasma Melatonin and Dexamethasone Suppression Test in Non-Seasonal Major Depressive Patients...

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Báo cáo khoa học: "Postmastectomy irradiation in breast in breast cancer patients with T1-2 and 1-3 positive axillary lymph nodes: Is there a role for radiation therapy" ppsx

Ngày tải lên : 09/08/2014, 09:20

... Out-come a Lateral, bMedial, cInvasive ductal carcinoma, dInvasive Paget’s disease, eDistance metastasis patients had lung metastasis and two had liver metastasis One patient had mediastinal involvement ... grade, extracapsular extension, lymphatic, vascular and perineural invasion, and ratio of involved nodes/ dissected nodes), and treatment-related factors (PMRT, chemotherapy and hormonal therapy) ... seventh rib Any relapse involving the axillary lymph nodes, and/ or other nodes in the infra or supraclavicular fossa or in the internal mammary chain was considered as a regional recurrence Any recurrence...

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Báo cáo y học: " The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir: is there a clinical advantage" potx

Ngày tải lên : 10/08/2014, 05:22

... and white colour) A) One patient with failing APV containing therapy after week 72 B) Another patient with a failing IDV/LPV treatment before start of SQV containing therapy Wiesmann et al AIDS ... has made substantive intellectual contribution to the study including acquisition-, analysis- and interpretation of data and finally drafting the manuscript JV assisted as consultant in patient-specific ... virological and immunological parameters were assessed at baseline before switch of therapy and are provided in Table All patient data was categorized in three groups concerning the follow-up therapy: ...

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Báo cáo y học: "Looking through the ''''window of opportunity'''': is there a new paradigm of podiatry care on the horizon in early rheumatoid arthritis" pot

Ngày tải lên : 10/08/2014, 21:24

... feature in many UK and European guidelines These are summarised in Tables and for both early and established disease Various recommendations are made for inclusion of podiatrists in the multidisciplinary ... apply and should be widely disseminated among podiatrists Therefore, under this new paradigm we propose to increase the knowledge and understanding of early RA, including the mandate for early ... design and manufacture capabilities where available Orthotics treatment can be combined with exercises, gait training, and therapeutic footwear, as well as joint protection and disease management advice...

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Báo cáo y học: " Is there a linear relationship between the Brief Psychiatric Rating Scale and the Clinical Global Impression-Schizophrenia scale? " doc

Ngày tải lên : 11/08/2014, 16:22

... revised the manuscript JI was responsible for checking the methodology of the study and evaluating the results of the statistical analysis In addition, all authors read and approved the final ... of the patients and the statistical analysis, and wrote the manuscript SM also performed the evaluation of the patients and Sawamura et al BMC Psychiatry 2010, 10:105 http://www.biomedcentral.com/1471-244X/10/105 ... scale Acknowledgements The authors wish to acknowledge Katsuji Nishimura, Takao Kanai, Ken Inada and Kaoru Sakamoto for providing us with very useful advice in this study Author details Department...

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báo cáo khoa học:" Gene-enhanced tissue engineering for dental hard tissue regeneration: (2) dentin-pulp and periodontal regeneration" pptx

Ngày tải lên : 11/08/2014, 23:22

... efficacy in clinical trials requires a combination of intraoral radiographic evaluation and clinical assessment of attachment gain Attempts to statistically analyze the effectiveness of these ... precludes the potential for cell- based approaches for enamel regeneration In contrast, the regeneration of dentin is feasible because dentin is in intimate contact with an underlying highly vascular and ... surface and the crevicular epithelium The goal is to retard the migration of crevicular epithelium into the space between the newly prepared root surface and the neighboring alveolar bone, thereby...

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Báo cáo khoa học: " Is there a special mechanism behind the changes in somatic cell and polymorphonuclear leukocyte counts, and composition of milk after a single prolonged milking interval in cows" pptx

Ngày tải lên : 12/08/2014, 18:22

... milk for analysis of casein and FFA were collected in the afternoon milkings, at days -1 and from all cows At days and casein and FFA was analysed in milk only from cows which during day had a pronounced ... draft and revise the manuscript EW participated in the practical work of the study, was main responsible for performing the statistical analyses, helped in interpreting the results and revising the ... All other analyses and preparations of smears for PMN counting were performed within h Statistical analysis Data of milk SCC, PMN, fat, protein and lactose were used in the statistical calculations...

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Báo cáo khoa học: "Bench-to-bedside review: Is there a place for epinephrine in septic shock" pptx

Ngày tải lên : 12/08/2014, 23:20

... correlating an increase in MAP with an increase in cardiac index [6] Using epinephrine as a first line agent, Moran et al [7] reported a linear relationship between epinephrine dosage and heart rate, ... epinephrine and propranolol also act on hemodynamics Therefore, alterations in the serum concentrations of catecholamine may affect the immunocompetence of the organism and may thereby affect the clinical ... catecholamine based on rational evaluation This is not the case for many situations in other clinical settings For example, catecholamines are used on the ward, during transportation, in the emergency...

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Báo cáo y học: "Tranexamic acid in cardiac surgery: is there a cause for concern" pps

Ngày tải lên : 13/08/2014, 21:21

... taking platelet active medication and having primary myocardial revascularisation This patient population appears not to have observed safety issues when tranexamic acid was administered [5] The ... study adds to the data questioning if tranexamic acid administration has a place in higher risk cardiac surgery and especially in surgery where a cardiac chamber is opened Competing interests In the ... the past years DR has acted as a paid consultant to Bayer Schering, Cubist and Curacyte, the pharmaceutical companies who have the potential blood-sparing agents aprotinin under review and Eccallentide...

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The US econom is there a way out of the woods

Ngày tải lên : 23/09/2015, 08:53

... for the three financial balances and changes in total output, using the same format as in Figure Percent of GDP -2 -4 1980 1985 1990 1995 2000 2005 2010 Historical Data and Soft Landing Scenario ... Growth and Main Sector Balances Growth Rate (percent) 10 Stage 4: Putting It All Together In Figures and we have drawn the implications of our assumptions for the growth rate in real GDP and the balances ... imbalances is that saving increases in the United States and falls elsewhere But this would be an incomplete and counterproductive remedy, unless there were also a mechanism, such as dollar devaluation,...

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