the tragic story of paolo and francesca was the subject
Tài liệu Báo cáo khoa học: Bioimaging of the unbalanced expression of microRNA9 and microRNA9* during the neuronal differentiation of P19 cells doc
Ngày tải lên :
18/02/2014, 17:20
... positions
and sequences used to amplify pri-miR9-1,
9-2 and 9-3. Arrows indicate the position
and orientation of the primers. Bold font
represents the sequence of mature miR9*
and italic fonts the ... sense and antisense strands of the
piRNA hairpin are involved in formation of the piR-
NA-interacting complex (piRC) and function in the
transcriptional gene silencing of retrotransposons and
genetic ... P19 cells;
the white bar represents mature miR9 and the black bar mature
miR9*, and the line with a triangular head indicates the ratio
(numerical values shown on the top of bar) of mature miR9...
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Trends in the European Investment Fund Industry in the Second Quarter of 2011 and Results for the First Half of 2011 potx
Ngày tải lên :
07/03/2014, 16:20
... including funds of funds, except for France, Germany and Italy for which the funds of funds data are
included in the other fund categories; (3) net sales of non-UCITS are included in "other" ...
D
D
o
o
m
m
i
i
c
c
i
i
l
l
i
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a
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t
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i
o
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n
n
The combined assets of the investment fund market in Europe, i.e. the market for UCITS and non-
UCITS, edged slightly lower in the second quarter of 2011 by 0.1 percent to stand at EUR ... this segment of the business accounted for just over 73 percent of
the fund market at end June 2011, with the remaining 27 percent composed of non-UCITS.
Table 7. Net Assets of the European...
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Trends in the European Investment Fund Industry in the Second Quarter of 2012 and Results for the First Half of 2012 pdf
Ngày tải lên :
07/03/2014, 16:20
... -8.5% -296 -12.6% -459
Total (incl. Ireland & Netherlands) 35,766
-1.0% -346 -0.9% -340
(1) No full data breakdown is available for Ireland and the Netherlands; (2) end June 2012 compared to ... of 2012
and
Results for the First Half of 2012
This report was prepared by Bernard Delbecque, Director of Economics and Research
EFAMA
The European Fund and Asset Management ... (EUR 1 billion). Luxembourg and Ireland attracted net inflows of
EUR 22 billion and EUR 17 billion, respectively, into bond funds during the quarter. On the other hand, money
market funds in...
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Báo cáo khoa học: The influence of temperature and osmolyte on the catalytic cycle of cytochrome c oxidase ppt
Ngày tải lên :
31/03/2014, 07:20
... collected and treated as
detailed in Materials and methods. An equation containing the sum of
three exponentials was fit to the data. The R
2
forthefitwasbetterthan
0.998; the fit is shown as the solid ... the time course of the absorb-
ance change at 443 nm. The difference between the steady
state values of the 276 K sample and the totally reduced
sample at 276 K are clearly much larger than the ... temperature in
the cuvette was monitored during the assay with a T-type thermo-
couple and was constant within ± 0.1 K over the course of the
measurement. The rate constant on the ordinate is a turnover...
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Tài liệu The King''''s Post Being a volume of historical facts relating to the Posts, Mail Coaches, Coach Roads, and Railway Mail Services of and connected with the Ancient City of Bristol from 1580 to the present time pdf
Ngày tải lên :
17/02/2014, 02:20
... occupation of Richard Bright and
Thomas Daniel and then Co-partners trading under the Firm of the Bristol Copper
Company but then the property of the said James Ford on[Pg 13] the South part and
extending ... £3,000.
There is still evidence in the building of the occupation of the Inland Revenue staff,
iron gates and spiked barriers in the first floor passage to cut off their rooms from the
Post Office ... business of the Bath
Post Office,[Pg 46] and of his cross post contracts, and the other on the house in
which John Palmer was born.
Soon after noon on the eventful day, the Bath postmen's band,...
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Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx
Ngày tải lên :
19/02/2014, 13:20
... ligand binding. The loop region of the upper domain
moves towards the active site of the enzyme, thus shielding
the substrates (and ligands) from bulk solvent. A detailed
thermodynamic study of ... 1UAE [11]), conformation. The
thiol group of C115 is highlighted in green and
the nitrogen atoms of R120 and K22 in blue.
The open form of MurA is unliganded (A) and
the closed conformation (B) ... importance of R120 for the
formation of the covalent fosfomycin adduct, we construc-
ted the K22V/R120V and K22V/R120K double mutants
(see Materials and methods) and repeated the analysis of
adduct...
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Báo cáo khoa học: Role of DptE and DptF in the lipidation reaction of daptomycin ppt
Ngày tải lên :
07/03/2014, 04:20
... with BamHI and NotI, and ligated into the same
sites of the pQTev vector to yield the plasmid pQTev-dptF.
The integrity of the plasmid was confirmed by sequencing.
The resulting plasmid was used ... features is of consider-
able importance for the development of selective
potent drugs.
The biosynthesis of the peptide core of these acidic
lipopeptides via nonribosomal peptide synthetases
(NRPSs) ... recognized by
the C domain of the initiation module of dapto-
mycin. That DptE and DptF are involved in the
lipidation process of daptomycin was first shown by
Miao et al. [1]. In their work, the daptomycin...
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Báo cáo khoa học: The importance of polymerization and galloylation for the antiproliferative properties of procyanidin-rich natural extracts doc
Ngày tải lên :
07/03/2014, 05:20
... adduct detected by the ESR spec-
trometer. The typical ESR signal of DMPO-OOH ⁄ DMPO-
OH was observed. The OH and O
2
-scavenging activity was
calculated on the basis of decreases in the DMPO-OH or
DMPO-OOH ... Maastricht University, the Netherlands
Colorectal cancer is the third most commonly diagnosed
cancer in the world and is one of the major causes of
cancer-associated mortality in the USA [1,2]. Epidemio-
logical ... treatment and the degree of polymerization
related to the bioavailability in the colon.
Procyanidins and monomeric catechins (Fig. 1) are
the main active polyphenols in grape and pine bark.
The difference...
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Báo cáo khoa học: Investigating the role of the invariant carboxylate residues E552 and E1197 in the catalytic activity of Abcb1a (mouse Mdr3) docx
Ngày tải lên :
07/03/2014, 06:20
... the
c-phosphate of the bound nucleotide across the
dimer [15] and the aromatic residue of the A-loop
stacks against the adenine moiety of bound
nucleotide and provides further stabilization and
specificity ... cleavage of the c-phosphate does occur in the
NBD with the mutation at the IC [36,38,39]. More-
over, these and other studies suggest that the IC
residues are involved in the formation of the NBD
dimer, ... motifs: the Walker A and
B motifs, the signature or LSGGQ motif and the
A-, D-, H- and Q-loops. These motifs are positioned
around the bound nucleotide and help to position
and maintain it in the...
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Revealing the Hidden Nature of Space and Time: Charting the Course for Elementary Particle Physics pptx
Ngày tải lên :
14/03/2014, 10:20
... 5. The Secretary of Energy and the Director of the Na-
tional Science Foundation, working with the White House Office of Science
and Technology Policy and the Office of Management and Budget and ... suggests that these impending
discoveries may transform our understanding of the origin of matter and energy
and the ongoing evolution of the universe.
The limitations of the Standard Model are ... exciting
periods in the history of physics.
One of the great scientific achievements of the 20th century was the develop-
ment of the Standard Model of elementary particle physics, which describes the
relationships...
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Báo cáo khoa học: The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein ppt
Ngày tải lên :
30/03/2014, 14:20
... 81% in the SH-SY5Y cells (Fig. 1A).
Neither ASO significantly affected the level of the mRNA
for the other ADAM, confirming the specificity of these
ASOs [19]. The ASOs reduced the level of their ... in the presence or absence
of APMA. In the majority of cases there was little difference
between the effect of inhibitors on the constitutive shedding
of ACE and the APMA-induced shedding of ... increase in the shedding of
APP upon incubation of the cells with APMA, the
shedding of ACE was increased several-fold. The soluble
form of ACE shed upon APMA stimulation was cleaved at
the same...
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Báo cáo Y học: Effect of ibuprofen and warfarin on the allosteric properties of haem– human serum albumin A spectroscopic study potx
Ngày tải lên :
31/03/2014, 23:20
... absorbance
properties of the chromophore without affecting the
coordination number or the spin state of the haem-iron,
and the quenching of the
1
H-NMR relaxivity. Values of
K
d
for ibuprofen and warfarin ... 10
28
M and n ẳ 1.0 ^ 0.1, in the absence of drugs,
and K
d
ẳ 1.5 ^ 0.2 10
27
M and n ẳ 1.0 ^ 0.1, in the presence of
ibuprofen and warfarin. The haem concentration was 1.0 Â 10
27
M.
The electronic ... constant (K
d
) and of the Hill coefficient (n )
for haem binding to HSA, in the absence and presence of
ibuprofen and warfarin. The K
d
value for ferric haem
binding to HSA, in the absence of drugs,...
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