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the theory of evolution by natural selection is a good example of how science proceeds

Báo cáo khoa học: Molecular basis of perinatal hypophosphatasia with tissue-nonspecific alkaline phosphatase bearing a conservative replacement of valine by alanine at position 406 Structural importance of the crown domain potx

Báo cáo khoa học: Molecular basis of perinatal hypophosphatasia with tissue-nonspecific alkaline phosphatase bearing a conservative replacement of valine by alanine at position 406 Structural importance of the crown domain potx

Báo cáo khoa học

... M, Amizuka N, Ozawa H & Oda K (2002) Reten-tion at the cis-Golgi and delayed degradation of tissue-non-specific alkaline phosphatase with anAsn153fi Asp substitution, a cause of perinatal ... perinatal hypophosphatasia withtissue-nonspecific alkaline phosphatase bearing a conservative replacement of valine by alanine atposition 406Structural importance of the crown domainNatsuko ... Dental Sciences, Japan2 Division of Oral Biochemistry, Niigata University Graduate School of Medical and Dental Sciences, Japan3 Division of Oral Health in Aging and Fixed Prosthodontics, Niigata...
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Tài liệu .An ARCO Book ARCO is a registered trademark of Thomson Learning, Inc., and is used herein under pptx

Tài liệu .An ARCO Book ARCO is a registered trademark of Thomson Learning, Inc., and is used herein under pptx

Tài liệu khác

... which is a standardized exam given at various locations in the United States and Canadaand around the world. Throughout North America and in many internationallocations, the GMAT is administered ... of international software piracy(E) disparage the attempts of the U.S. government to control softwarepiracy The correct answer is (B). This question, typical of the GMAT, asks about the main point of the ... wide of a margin as anycandidate in the state’s history. (A) she was reelected with as wide of a margin as any candidate in the state’shistory.(B) she had been reelected with as wide of a margin...
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Báo cáo khoa học: Inactivation of phosphorylase is a major component of the mechanism by which insulin stimulates hepatic glycogen synthesis doc

Báo cáo khoa học: Inactivation of phosphorylase is a major component of the mechanism by which insulin stimulates hepatic glycogen synthesis doc

Báo cáo khoa học

... glycogen synthesis by inactivation of phosphorylase is associated with both activation andtranslocation of glycogen synthase, and that the formermechanism alone cannot explain the stimulation of glyco-gen ... a; (b)thatsuppression of GSK-3 activity, in the absence of inactiva-tion of phosphorylase, causes a large activation of glycogensynthase but a small stimulation of glycogen synthesis; (c)that the stimulation of ... CP-91149 caused activation of glycogen synthase and translo-cation of the protein from a soluble to a particulate fractionand mimicked the stimulation of glycogen synthesis by insulin. The stimulation...
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Báo cáo sinh học:

Báo cáo sinh học: " High Chromosome Number in hematological cancer cell lines is a Negative Predictor of Response to the inhibition of Aurora B and C by GSK1070916" potx

Điện - Điện tử

... HP,Yokoyama A: Analysis of Aurora B kinase in non-Hodgkin lymphoma. LabInvest 2009, 89:1364-1373.5. Ikezoe T, Yang J, Nishioka C, Tasaka T, Taniguchi A, Kuwayama Y,Komatsu N, Bandobashi K, Togitani ... Bachman,Mary Ann Hardwicke, Richard Wooster and Yan DegenhardtAbstractBackground: Aurora kinases play critical roles in mitosis and are being evaluated as therapeutic targets in cancer.GSK1070916 is a ... reflect the rela-tive expression of the Aurora genes at the time of mitosis, the relationship of Aurora expression and response toGSK1070916 is still unclear. In a s ubse quent analysis of the background...
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o cáo hóa học:

o cáo hóa học:" High Chromosome Number in hematological cancer cell lines is a Negative Predictor of Response to the inhibition of Aurora B and C by GSK1070916" ppt

Hóa học - Dầu khí

... Elmer). For analysis of cell growth inhibi tion, the datawasplottedasthepercentoftheDMSO-treatedcontrol samples and the data was fit using the IDBSXLfit4 software for data analysis. Values from ... participated in the design of the study and performed the statistical analysis. YD, MAH, CMconceived of the study, and participated in its design and coordination andhelped to draft the manuscript. ... reflect the rela-tive expression of the Aurora genes at the time of mitosis, the relationship of Aurora expression and response toGSK1070916 is still unclear. In a s ubse quent analysis of the background...
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The Project Gutenberg EBook of Lamarck, the Founder of Evolution, by Alpheus Spring Packard pptx

The Project Gutenberg EBook of Lamarck, the Founder of Evolution, by Alpheus Spring Packard pptx

Điện - Điện tử

... generousdisposition are constantlyrevealed in his writings. The name of Lamarck has father of Lamarck and of Lamarck himself. The JesuitSeminary at Amiens was alsovisited, in order to obtain traces of ... the eminent malacologist andanthropologist. The notices by Professor Mathias Duval and by L. A. Bourguin have been of essential service.As regards the account of Lamarck’s speculative andtheoretical ... atwww.gutenberg.orgTitle: Lamarck, the Founder of Evolution His Life and Work of the Lamarckian theory of organic evolution, so that it hasbecome a rival of Darwinism; the prevalence of these...
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Project Gutenberg''''s The Doctrine of Evolution, by Henry Edward Crampton pdf

Project Gutenberg''''s The Doctrine of Evolution, by Henry Edward Crampton pdf

Điện - Điện tử

... thislatter part of the series, the subject of physical evolution is first considered, andthis is followed by an analysis of humanmental evolution; the chapter on social evolution extends the ... factsabout plants and animals may beinteresting and may possess a certainintellectual value, but nothing more. The investigation of man and of men and of human life is regarded by the majority as a mere ... already a fund of informationthat can be directly utilized during the coming discussions; for if evolution is trueas a universal principle, then it is as natural and everyday a matter as natureand...
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Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx

Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx

Báo cáo khoa học

... 5-GACGAGATTATCAGATTTTACGC-3 and 5-AACTGGTGAAGCGGAAGAGAC-3, PTI1-4 (At2g47060): 5-CCCCAAAGAAAATGAGTTGCT-3 and 5-GCATCATTTCCTGGAGGAAAG-3.AcknowledgementThis project was supported by grants from the Aus-trian Science ... [c-32P]-ATP. MBP was used as an artifi-cial substrate to assess the kinase activity and GST alone wasused as a negative control. The top panel shows the kinase assayvisualized by autoradiography and ... ACTIN2gene as an internal standard. PCRs were performed using the following primers: ACT2 (At3g18780): 5-ACATTGTGCTCAGTGGTGGA-3 and 5-CTGAGGGAAGCAAGAATGGA-3, OXI1 (At3g25250): 5-GACGAGATTATCAGATTTTACGC-3...
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Báo cáo khoa học: Xenopus Rbm9 is a novel interactor of XGld2 in the cytoplasmic polyadenylation complex pptx

Báo cáo khoa học: Xenopus Rbm9 is a novel interactor of XGld2 in the cytoplasmic polyadenylation complex pptx

Báo cáo khoa học

... homologs are poly (A) polymerases. Proc Natl Acad Sci USA 101, 4407–4412.18 Nakanishi T, Kubota H, Ishibashi N, Kumagai S,Watanabe H, Yamashita M, Kashiwabara S, Miyado K& Baba T (2006) ... the 3Â-UTR of regulated mRNAs.Although cytoplasmic polyadenylation is regulated by a protein complex at the 3Â-end of the mRNA, PAP is the only known enzyme capable of elongating the poly (A) tail. This ... RNA helicase in translational repression is anRNA-mediated oligomer. Nucleic Acids Res 32, 1325–1334.5 Nakahata S, Kotani T, Mita K, Kawasaki T, Katsu Y,Nagahama Y & Yamashita M (2003)...
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Báo cáo khoa học: Epl1, the major secreted protein of Hypocrea atroviridis on glucose, is a member of a strongly conserved protein family comprising plant defense response elicitors potx

Báo cáo khoa học: Epl1, the major secreted protein of Hypocrea atroviridis on glucose, is a member of a strongly conserved protein family comprising plant defense response elicitors potx

Báo cáo khoa học

... cerato-platanin domain, and a blastp search always yielded the members of the cera-to-platanin family as the best hits. It is possible thatthey represent an ancestral cerato-platanin memberthat is ... C-terminus of the protein contains two helices, separated by a 14amino acid strand.interproscan analysis [22] of Epl1 showed the affi-liation of this protein to the cerato-platanin family(IPR010829). ... human allergens and path-ogenesis-related proteins (As-CG of Coccidioides immi-tis, Aca1 of Antrodia camphorata and Aspf13 of Aspergillus fumigatus).It should be noted that a low similarity of...
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Báo cáo Y học: Repression of FasL expression by retinoic acid involves a novel mechanism of inhibition of transactivation function of the nuclear factors of activated T-cells pptx

Báo cáo Y học: Repression of FasL expression by retinoic acid involves a novel mechanism of inhibition of transactivation function of the nuclear factors of activated T-cells pptx

Báo cáo khoa học

... random hexamer(Pharmacia, Uppsala, Sweden). The PCR primer sequencesused were as follows. FasL (forward: 5Â-ATGTTTCAGCTCTTCCACCTACAGAAGGA-3Â,reverse:5Â-CAGAGAGAGCTCAGATACGTTGAC-3Â); and b-actin ... a novel mechanism of NFAT blockage that is mediated by a subset of the r etinoid receptors.All-trans-RA inhibits the DNA binding activity of NFATTo understand the molecular m echanism of RA-inducedinhibition ... modulates the activities of the enzymes thataffect nuclear translocation and transcriptional activity of NFAT. The NFAT proteins regulate the expression of FasL and a discrete set of cytokines...
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Báo cáo khoa học: The Promyelocytic Leukemia Zinc Finger (PLZF ) gene is a novel transcriptional target of the CCAAT-DisplacementProtein (CUX1) repressor ppt

Báo cáo khoa học: The Promyelocytic Leukemia Zinc Finger (PLZF ) gene is a novel transcriptional target of the CCAAT-DisplacementProtein (CUX1) repressor ppt

Báo cáo khoa học

... data analysis that was originally per-formed at the Penn Microarray Facility (University of Pennsylvania, Philadelphia, PA, USA). We also thankDrs Angus M. Sinclair and Richard H. Scheuermann(UT ... (5Â-gaaaggcatcccgaacgcat-3Â); Chip2upprimer (5Â-aaatgtcttgaccagccgtc-3Â) and Chip2dw primer(5Â-gaaacaaaggcctctcccag-3Â); Chip3up primer (5Â-gctttgcagt-cagaatggtc-3Â) and Chip3dw primer (5Â-ctgagcactgactac-gaaac-3Â). ... rat, mouse and humanCUX1 was kindly provided by Dr Julian Downward [50].Two bases (in capitals) were further mutated (5Â-aagaagaacaGAccagaggattt-3Â) to be used as a control. The Caco-2 ⁄ 15...
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Báo cáo khoa học: The leech product saratin is a potent inhibitor of platelet integrin a2b1 and von Willebrand factor binding to collagen pdf

Báo cáo khoa học: The leech product saratin is a potent inhibitor of platelet integrin a2b1 and von Willebrand factor binding to collagen pdf

Báo cáo khoa học

... hemato-phagy. The presence of anticoagulants in the salivaryglands of the leech, Hirudo medicinalis, was originallydiscovered by Haycraft in 1884 and led to the isola-tion of hirudin, a potent antithrombin ... molecules, LAPP (anapproximately 13 kDa leech antiplatelet protein isola-ted from Haementeria of cinalis) and calin and sara-tin (approximately 65 kDa and 12 kDa proteins,respectively, both isolated ... significantimplications for the use of saratin as a tool to inhibitplatelet–collagen interactions, and may provide the basis for the therapeutic use of saratin as a potentantithrombotic agent.ResultsDelayed...
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Báo cáo khoa học: Myocyte enhancer factor 2 (MEF2) is a key modulator of the expression of the prothoracicotropic hormone gene in the silkworm, Bombyx mori ppt

Báo cáo khoa học: Myocyte enhancer factor 2 (MEF2) is a key modulator of the expression of the prothoracicotropic hormone gene in the silkworm, Bombyx mori ppt

Báo cáo khoa học

... Japan2 National Institute of Agrobiological Sciences (NIAS), Ibaraki, Japan3 Graduate School of Science, Nagoya University, Aichi, Japan4 Graduate School of Bioagricultural Sciences, Nagoya ... Kawakami A, Kataoka H, Oka T, Mizoguchi A, Kimura-Kawakami M, Adachi T, Iwami M, NagasawaH, Suzuki A & Ishizaki H (1990) Molecular cloning of the Bombyx mori prothoracicotropic hormone. Science 247, ... cellsthroughout the brain lobes and at the midline in the subesophageal ganglion (SG) (Fig. 1A) . The axonsemanating from the somata of the two pairs of lateralcells extend towards the pars intercerebral...
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The Project Gutenberg EBook of Darwin, and After Darwin (Vol. 1 and 3, of 3), by George John docx

The Project Gutenberg EBook of Darwin, and After Darwin (Vol. 1 and 3, of 3), by George John docx

Điện - Điện tử

... one hand, and of clearlyrecognising the relation between them on the other, is the importance of not beingscared by the Bugbear of Speculation. The spirit of speculation is the same as the spirit ... andin Man8519. The same, showing variation in the Orang8520. Human ear 8621. Fœtus of an Orang 8722. Vestigial characters of human ears 8823. Hair-tracts on the arms and hands of Man, as compared ... his limitations of truescientific work in natural history to the collecting and arranging of species of plants and animals. In accordance withthis view, the status of a botanist or a zoologist...
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