... well They include constraints on the supply of labor and other inputs, upward pressure on wages and rents, congestion of infrastructure, and (if fiscal incentives are provided to the locating ... explain it, or at least the part of it that is not explained by observable indicators of labor quality.” Other theories to explain the size-wage effect have surfaced since the Brown and Medoff ... innovation Small firms are the great innovators in some industries, while large firms are the great innovators in others Moreover, small and large businesses interact in innovative activity The...
... and ciliated epithelial cells inthe adult lung [11] HFH-4 induces the expression of βtubulin IV inthe pseudoglandular stage, and promotes the differentiation of ciliated epithelial cells Other ... [66] The binding of PTN with syndecan-3 induces neurite outgrowth of embryonic neurons [67] Heparitinase, which cleaves the heparin sulfate chain and disrupts the binding of PTN, inhibits PTN-induced ... tips It binds to the FGFR2b on the epithelial cells and transmits a signal to induce the initiation ofthe lung bud [17-22] Recombinant FGF10 alone can induce budding inthe lung epithelial explants...
... partners and their roleinthe developing cytoskeleton The work in this thesis focuses on the developing fly eye, the targeting of axons from the eye to the brain andthe anchoring of posterior ... critical roles in regulating the guidance of both crossing and non-crossing axons at the ventral midline ofthe developing vertebrate spinal cord andthe Drosophila ventral nerve cord For example, these ... requirement of this interaction for normal eye developmentInthe absence of bif, the actin rich rhabdomeres, ofthe fly eye, lose their star like appearance inthe pupal stages and appear compressed,...
... enthalpies of binding and stoichiometries were determined from the binding isotherm by fitting a : binding model to the data using the software provided by the manufacturer Results Reaction of fosfomycin ... replacement of R120 by lysine reduces the probability of forming the fully closed form ofthe protein The results obtained with the K22V/R120K double mutant protein point toward a central roleof arginine ... chain of K22 participates in fosfomycin binding, thus providing a rationale for the loss of fosfomycin binding to the K22V and K22E mutant proteins However, two other positively charged amino...
... assistance Maintaining and strengthening the contributions ofthe science, engineering, and medical capabilities ofthe United States to programs administered by USAID are the themes ofthe report These ... Engineering in providing services to the government, the public, andthe scientific and engineering communities The Council is administered jointly by both Academies andthe Institute of Medicine ... Academy of Engineering The Institute of Medicine was established in 1970 by the National Academy of Sciences to secure the services of eminent members of appropriate professions inthe examination of...
... The motif present in DptF is GLDSV, indicating that this putative ACP domain is one ofthe few ACPs in which valine replaces isoleucine (I) or leucine (L) inthe conserved sequence To determine ... Assay Fig In vitro phosphopantetheinylation of apo-DptF and apoAcpK Coomassie blue-stained SDS–PAGE gel (left) and in- gel fluorescence (right) ofthe fluoresceinyl-ACP (+) indicates the reaction ... carrier proteins (ACPs) [14,15] The genes dptE and dptF are localized immediately upstream ofthe NRPSs of A21987C The resulting proteins DptE and DptF were predicted to be involved inthe lipidation...
... understand the meaning ofthe questions in this section Each session took 30 including instructions at the beginning, the listening comprehension task, and completion ofthe questionnaire The questionnaire ... placement inthe IEP was determined on the basis of an in- house placement test of listening, reading, and writing skills (reliability coefficients for the listening and reading sections of this ... B., & Lynch, K (1999) Offering a hand to pragmatic understanding: Theroleof speech and gesture in comprehension and memory Journal of Memory and Language, 40, 577–592 Lansing, C R., & McConkie,...
... businesses, the traditional target client group of savings banks By capturing and channelling more ofthe remittances into the financial system and intermediating the flow ofthe resources, savings ... disbursing of loans and collecting loan repayments Another promising track for savings banks is to invest their savings deposits in microfinance institutions by specialising 18 Microfinance Information ... countries andin Latin America and Asia, the figures also remain well below the average requirement ofthe banking system The microcredit schemes of savings banks Although savings banks are savings...
... choose either ofthe latter two responses are defined as ―certain‖ youth, and there are 333 youth inthe final weighted sample of certain youth Youth who respond that their chances of attending a ... or less are defined as ―uncertain.‖ There are 120 youth in this sample, and 453 inthe combined (certain and uncertain) sample.5 Variables In this section, variables of interest and control variables ... important for explaining wilt Inthe case of income, youth living in low-income households experience higher levels of wilt (45%) than youth living in either modest-income (35%) or high-income (23%)...
... rolein protein stability [8], and their involvement in interactions with cations offers new perspective inthe analysis ofthe contribution of ions as cofactors in protein folding [38] andin ... those observed for the wild-type, indicating the involvement of Glu53 and Asp287 inthe interaction with the cation (Fig 1E,F) The regain of aromatic chirality at 295 nm andinthe 260270 nm region ... [2] The solid lines through the mutants unfolding data points (lled symbols) are intended to guide the eye ofthe reader and not represent the tting ofthe data Reversibility points are indicated...
... ADAM10 and TACE are involved inthe shedding of APP, neither ADAM is involved inthe shedding of ACE Furthermore we show that APMA can distinguish between the shedding of ACE and APP Materials and ... expressing ACE were transfected with the ASOs and then exposed to APMA andthe levels of soluble ACE inthe medium examined (Fig 5) APMA caused a twofold increase inthe shedding of ACE from the ... ADAM10 and TACE play a roleinthe a-secretase shedding of APP, neither protease was responsible for the shedding of ACE APMA stimulates the shedding of ACE but not APP The effect ofthe organomercurial...
... facility level in Zambia served inthe capacity of district managers of health programmes The finding that the nurses in Sudan were less involved in planning of activities (15.2% in polio andin measles) ... measles Roles of nurses and midwives in SIAs for polio and measles The involvement ofthe nurses and midwives in activities related to polio and measles SIAs is presented in Table In general, the ... midwives inthe expanded programme on immunization Study objectives The objectives of this study were to document the roles, functions and contribution of nurses and midwives inthe delivery of routine...
... part ofthe risk group Inthe case ofthe first LEs combination exposed at Table of breaking up with a boyfriend/girlfriend and failing a grade in school involves a sufficient impact to be part of ... in attenuating thestressof life events J Behav Med 1981, 4:139-157 25 Felsten G: Gender and doping: use of distinct strategies and associations with stressand depression Anxiety, stress, and ... Spain Authors’ contributions JMV, LR, and JA participated inthe conception and design ofthe study EVO, SRF, GV and JAPV analyzed the data EVO, JMV, MH, MF, LR and JA participated inthe drafting...
... Engineering in providing services to the government, the public, andthe scientific and engineering communities The Council is administered jointly by both Academies andthe Institute of Medicine ... president ofthe National Academy of Engineering The Institute of Medicine was established in 1970 by the National Academy of Sciences to secure the services of eminent members of appropriate professions ... distinguished scholars engaged in scientific and engineering research, dedicated to the furtherance of science and technology and to their use for the general welfare Upon the authority of the...
... years) andthe ’old’ (> 65 years) rings (cambial age) Inthe final stage, the curve ofthe growth indices IC0 was modelled according to the available meteorological parameters, using a linear ... residuals ofthe regression are analysed using the F ratio: , CO was Secondly, was The average curve of these growth indices according to calendar years was calculated with the aim of determining the ... In contrast to these results, there was no significant increasing trend inthe average radial growth rate found in a preliminary analysis using the same methodology in northeastern France using...
... ubiquitination of various target proteins, andthe intracellular domain ofthe Notch receptor (involved inthe maintenance of cells in an undifferentiated state), both of which notably contain ankyrin repeat ... vascularity and inflammatory signalling pathways Inthe present review we focus on current knowledge ofthe regulation ofthe HIF pathway, and then consider the potential roleof hypoxia inthe pathogenesis ... in RA, and this may yield further insight into the links between hypoxia, angiogenesis, inflammatory cell trafficking and matrix breakdown in RA Competing interests The authors declare that they...
... cyclin E in all invasive carcinomas andinthe subgroup of IDC This may be due to the early stage ofthe disease The major limitation of this study is the small size ofthe study group Further ... positive staining in less than 5% of nuclei); low staining = moderate to strong positive staining in 5% to 50% of nuclei; high staining = moderate to strong positive staining in more than 50% of nuclei ... follow up of more than 36 months There were 59 infiltrating ductal carcinomas (not otherwise specified and variants) and infiltrating lobular carcinomas The infiltrating ductal carcinoma group included...
... at the start of night prolongation, or 12 wk, an important roleinthe possibility ofthe buds to attain a deeper stage of dormancy Only the 12 wk old plants of northern origin had no flushing ... the chilling requirement to break winter dormancy in Scots pine has been stressed (e.g., Wareing, 1951; Vegis, 1965; Sarvas, 1974) Inthe following,I will use the working definition of dormancy ... effective in breaking dormancy of any stage The temperature, +2 to deeper the dormancy, the longer the time needed for a complete break References Dormling (1975) Photo- and thermoperiodic reactions in...
... ubiquitination of various target proteins, andthe intracellular domain ofthe Notch receptor (involved inthe maintenance of cells in an undifferentiated state), both of which notably contain ankyrin repeat ... vascularity and inflammatory signalling pathways Inthe present review we focus on current knowledge ofthe regulation ofthe HIF pathway, and then consider the potential roleof hypoxia inthe pathogenesis ... in RA, and this may yield further insight into the links between hypoxia, angiogenesis, inflammatory cell trafficking and matrix breakdown in RA Competing interests The authors declare that they...
... Figure Lack of HPV16 Infection inthe absence of cathepsin B Lack of HPV16 Infection inthe absence of cathepsin B HPV16 infection levels in cathepsin B and cathepsin L deficient (-/-) and wild ... amounts of time with cathepsin B or cathepsin L protease, Figure Cathepsin B and L treatment of HPV16 increases binding Cathepsin B and L treatment of HPV16 increases binding Reporter virus binding ... cathepsin L enhanced infectivity by cleaving and removing a highly glycosylated mucin domain inthe Ebolavirus glycoprotein and resulted in increased binding suggesting that cathepsins are indeed...