... placed nursesin this study inthe persuasion stage of adoption, overall In other words, they were aware of and believed inthe value ofthe practices but were not using them to make clinical ... Use of nursing practice research findings Nursing Research 1987, 36:344-349 Michel Y, Sneed NV: Dissemination and use of research h findings in nursing practice Journal of Professional Nursing ... [15], nurses were asked to indicate the extent to which they use 16 sources of knowledge, including P&P manuals, in their practice Most nurses (81.9%) reported using the knowledge they obtain from...
... throughout the world bears little resemblance to teosinte, the original ancestor of corn The newer techniques involving genetic engineering, on the other hand, allow for the transfer of a few genes in ... create signiÞcant changes inthe genetic makeup of plants and animals due to the random recombination and sorting of thousands of genes As a result of intervention by people, the hybrid seed corn ... commercially introduced inthe U.S in 1996 and have been rapidly adopted by farmers It has been estimated that 24% ofthe corn and almost 70% ofthe soybeans and cotton grown inthe U.S in 2001 were...
... at the beginning ofthe period, which favors a finding of higher growth among small firms, rather than at the end ofthe period Table A1 decomposes job growth from the second quarter of 2000 into ... directly by the firm—would certainly suggest this to be the case In reality, however, it is often the effects on other firms inthe area the indirect effects—that carry the greatest weight inthe net ... misleading to measure net employment changes as total employment in a size class at the end ofthe year less total employment inthe size class at the beginning ofthe year The numbers presented in...
... helix ofthe third cluster of CHCs is part ofthe inter-domain segment and the other helix lines the boundary between the major domain and the N-terminus (Fig 1) Therefore, the formation ofthe ... at the value determined from the amino acid sequence (45 320 Da) Measurement ofthe Kd of PLP binding equilibrium PLP binding equilibria were analyzed taking advantage ofthe protein intrinsic ... explain the increase ofthe dissociation constant ofthe monomer–dimer equilibrium determined by the mutations The results obtained inthe present study also show that the monomeric form of the...
... of GSK3 (using Li or SB-415286) appears to be sufficient for inducing activation of GS in muscle and fat cells, and that inhibition ofthe kinase potentiates insulin action in muscle of insulin-resistant ... GSK3 inhibition improves insulin responsiveness in muscle of insulin resistant animals it had no insulin potentiating effect in skeletal muscle of lean animals [39,41] To assess whether chronic inhibition ... (1994) The inhibition of glycogen synthase kinase-3 by insulin or IGF-1 inthe rat skeletal muscle cell line L6 by wortmannin, but not rapamycin: evidence that wortmannin blocks activation of the...
... placement inthe IEP was determined on the basis of an in- house placement test of listening, reading, and writing skills (reliability coefficients for the listening and reading sections of this ... including instructions at the beginning, the listening comprehension task, and completion ofthe questionnaire The questionnaire was completed after the listening task so as not to bias any ofthe ... people, pointing out that in such circumstances visual cues would be of little to no value This is a very specific interpretation ofthe meaning of lecture Having examined over 20 definitions of the...
... businesses, the traditional target client group of savings banks By capturing and channelling more ofthe remittances into the financial system and intermediating the flow ofthe resources, savings ... disbursing of loans and collecting loan repayments Another promising track for savings banks is to invest their savings deposits in microfinance institutions by specialising 18 Microfinance Information ... analysis ofthe creditworthiness and the repayment capacity of their clients, a domain where they have a high level of expertise, while savings banks could make use of their front and back of ce...
... > h from the start of glucose infusion For the calculation of glycogen C6 changes, data acquired within h ofthe start ofthe glucose infusion was not included to avoid any in uence of transient ... the initial rate of label incorporation into glycogen C6 relative to the rate of label incorporation into glycogen C1 reflects the relative isotopic enrichment of Glc6P inthe C6 relative to the ... should the tail vein fail, which was the case in only three animals, the data of which were included After the lines were inserted, pentobarbital was infused continuously at 4.8–6.0 mgÆkg)1Æh)1 The...
... Tyr These mutations may in uence the shape and volume ofthe acyl binding pocket and thereby alter the binding mode and affinity ofthe enzyme for PAA and derivatives thereof, while maintaining the ... aromatic phenylalanines and the phenyl ring ofthe substrate play an important rolein substrate binding The large effect ofthe mutations on the acylation rate indicate that these residues are ... results indicate that mutating bF57, which is located ˚ at the bottom ofthe binding pocket at A from the nucleophilic serine, does in uence the rate of formation ofthe acyl-enzyme, as judged by the...
... surprise The duration ofthe Credit Suisse Leveraged Loan Index is significantly lower than durations inthe traditional fixed income asset classes, reflecting the prevalence of floating rate instruments ... upon market or other conditions and are current as ofthe date at the beginning ofthe document The opinions expressed in this material are not necessarily those held by Russell Investments, its ... spread is the market-determined spread paid to the investor for taking on the credit risk (historically the normal range has been 3%–8%, depending on the riskiness of a loan) The credit spread reflects...
... of E187 remained the same, but the pKa of E399 clearly increased Actually, the substitution of R97 by methionine or lysine resulted inthe same increment inthe pKa of E399 (Table 2) Therefore, ... function as the catalytic proton donor Thus, interactions between E399 and Y331 or R97 may be key elements inthe determination of Sfbgly50 pH optimum Theroleof arginine inthe modulation ofthe b-glycosidase ... the apolar side chain of F331 Thus, the increment inthe pKa of E399, in addition to it being closer to E187, may have resulted in a large shift inthe pKa of E187 Changes inthe dielectric constant...
... present, the rate-limiting step inthe synthesis of dNTPs ⁄ NTPs is not the conversion of (d)NDPs to (d)NTPs, as the catalytic efficiency of NDK is high [7–9] The regulatory mechanism in dNTPs ... 6-His tag and a thrombin cleavage site were introduced to the N-terminus ofthe recombinant proteins Tryptophans, coded by UGA codons in UMPK and AMPK, were mutated to UGG using the sitedirected mutagenesis ... Table The effect of ATP concentration on the equilibrium concentration of labelled adenine nucleotides The initial concentration of [3H]AMP was 100 lM and the concentration of MgCl2 was 10 mM The...
... confounders were included inthe final logistic regression model if they changed the odds ratio of kneeling and squatting by more than 10% in at least one category Inthe final model, the following confounders ... between the questionnaire and observation ratings of 0.49 for frequency of lifting, carrying, and transferring 6–15 kg Concerning the frequency of lifting, carrying, and transferring 6–15 kg, the ... number of squatting and the duration of kneeling work D'Souza et al [20] examine the relationship between the daily amount of kneeling and knee osteoarthritis inthe subset of participants at the...
... quantities of Na and Cl inthe + leaves In coastal species, in normal conditions, the absorption of sea salt is limited by the normal defence mechanisms ofthe leaves, but inthe cases examined here the ... binds to the epicuticular wax structures since it is lipophilic, and is therefore not removed by rinsing However part ofthe chlorides absorbed by the needle are released during rinsing Inthe ... surfactants they transport, occur rather infrequently within the total number of samples examined Finally, the ratio MBAS/Cl is interesting because it varies considerably according to the matrix in which...
... registery of our hospital in order to reach the reports of their conventional imaging examinations and other investigations We couldn’t get the results ofthe medical examinations ofof these patients ... important limitation that the number of patients is small especially inthe first group, the number of studies inthe literature investigating theroleof PET inthe diagnosis of distant metastasis ... accepted the cut off SUVmax value as 2.5 in their study at which theroleof PET/CT was investigated, and they found out the Page of sensitivity ofthe technique 40% [12] In our study, because there...
... between the innate and adaptive parts ofthe immune system that might be an interesting target for the immunotherapy of inflammatory autoimmune diseases [26,27] Roleof IL-17 inthe pathogenesis of ... Beer Y: Interleukin-17 enhances tumor necrosis factor alpha-induced synthesis of interleukin 1, 6, and in skin and synovial fibroblasts: a possible role as a ‘fine-tuning cytokine’ in inflammation ... resulted in elevated levels of IL-1β protein inthe synovium [41] Intriguingly, blocking of IL-1α/β with neutralizing antibodies had no effect on the IL-17-induced synovial inflammation and joint...
... block inflammation in afflicted organs, such as the kidney, the joints, or the skin However, in view ofthe autoimmunogenic potential of inhibiting TNF, we tested TNF inhibition as a means to interfere ... TNF often is a survival signal (green lines) and plays a rolein maintaining survival niches for long-lived plasma cells (PlasmaC) Some of these effects are indirect in part, involving cytokines ... interfere with the inflammatory response in SLE by administering only an induction regime of four infusions of infliximab within 10 weeks rather than by planning for long-term therapy Evidence...
... at the same three sites as the symptomatic subjects prior to an injection of cc of1 % lidocaine inthe left thigh, and then re-evaluated for PPT within minute ofthe injection The purpose ofthe ... contrast, the increase in cervical range -of- motion observed inthe symptomatic cohort following the injections suggests that the initial finding of reduced motion was either a result of peripherally ... explained the finding as the expression of an abnormal processing of nociceptive information inthe brain and spinal cord [2-7] Others have postulated that chronicposttraumatic myalgia (muscle pains)...
... increase inthe expression ofthe gene inthe DAA fruit ofthe infiltrated plant compared to the expression inthe DAA fruit ofthe WT The analysis ofthe CaOvate genomic sequences obtained from the ... contained the part ofthe cDNA sequence also coding for the DUF623 domain The choice of including this part ofthe gene was consistent with the idea to simulate by VIGS what seems to be the case in ... studied Page of 16 VIGS of CaOvate in cv “Round” In order to obtain further evidence for theroleof CaOvate in determining fruit shape in cv “Round”, the VIGS technique was used VIGS ofthe Pds gene...