... LIKELIHOODS of tagpairs Instead ofa separate tag-pair error likelihood table to assess the grammaticality, the same tag-pair frequency table is used for tag-assignment and error-detection The tag-pair ... that this approach was impractical because ofthe time and effort required to collect the necessary data In any case, an alternative technique which managed without a separate table of tag-pair ... tag-pair likelihood is a function ofthe frequency of that sequence of two tags in a sample of tagged text, compared tothe frequency of each ofthe two tags individually An important advantage...
... management and treatment received Consequently national data on the management of ovarian cancer is sparse Some international data are available from GLOBOCAN and EUROCARE andare valuable for the ... report has highlighted the lack of data available to assess the burden ofthe disease based on the stage andthe type of ovarian cancer It is clear that there are difficulties in the collection and ... care to assess the relationship between the duration of symptoms and ovarian cancer outcome 2.1 Awareness of symptoms and signs Early recognitionof ovarian cancer symptoms Ovarian cancer has...
... bound and compared to our capacity figures very low We have summarized the average and maximum testing capacity in appendix The ratio ofthe maximum capacity tothe average capacity available is about ... asked the labs to consider an estimation ofthe average and maximum number of tests based on the number of tests that theyare able to conduct per year, as well asthe number of tests they conducted ... be a share of 60% The data exploration has shown a considerable variability in the prices for single tests andthe impact of three factors causing this variability The first factor that has caused...
... considering factors such asthe quality and price of available transport options Various factors can affect travel demands, as summarized below (Goodwin 2012b) Some of these factors are well recognized ... second half, but the decline has stopped, and Class track mileage increased slightly between 2000 and 2002 Many major rail lines and terminals are now being upgraded to accommodate more rail traffic ... travel asthey earn more and become parents, theyare unlikely to drive as much asthe Baby Boom generation Similar trends are occurring in other developed countries (Le Vine and Jones 2012) Car...
... 70 macrophage tropism and is associated with brain infection and dementia Proc Natl Acad Sci USA 2006, 103:15160-15165 Martín-Garc a J, Cao W, Varela-Rohena A, Plassmeyer ML, GonzálezScarano ... viruses to test for the ability of various Env to mediate infection, Env-mediated cell -to- cell fusion assays are also commonly usedto evaluate their ability to interact with receptors and mediate ... hours at 37°C At 2–3 days post-infection, the cells were washed with PBS and lysed, andthe amount of entry mediated by each Env was measured by detecting luciferase activity (Luciferase Assay System,...
... concern ofa potential pectoralis muscle rupture Upon the repeat evaluation by the orthopedic team, an expanding hematoma was appreciated in the axilla and anterolateral chest wall Additionally, ... complained of left arm pain Her past medical history was relevant for chronic alcohol abuse On first evaluation, the left arm appeared cooler than the right arm, and there was a gross deformity and ... revealed an intact 5/5 motor function ofthe left hand and intact sensation to light touch and 2point discrimination The radial pulse was symmetrically palpable (2+) The patient was radiographically...
... example, the focal adhesion kinase/cSrc, andthe small GTPases Ras and Rho) and adaptors (for example, Cas/Crk and paxillin) that assemble within dynamic adhesion structures, including focal adhesions ... head region tothe integrin β cytoplasmic tail causes dissociation ofthe α and β tails and induces a conformational change in the extracellular region that increases its affinity for its ligand ... Integrins can be activated intracellularly by signals from G-protein-coupled receptors that lead to phosphorylation ofthe cytoplasmic domain ofthe β subunit The association ofthe α and β cytoplasmic...
... decreases With the increase in salinity, the evaporation of water decreases due to increase in ion activity andthe reduction of thermodynamically spontaneous change ofa liquid phase into a vapour ... collectors is taken as outlet temperature ofthe parallel combination Each flat plate collector has an area of 1.35m2 inclined at an angle equal to latitude of Chennai (13o) facing towards due ... condensation The outlet temperature from the flat plate collectors, latent heat and refined latent heat of vaporization of water from each stage and specific heat capacity of water from each stage are averaged...
... neutral and alkaline pH; PhyH-DII was less stable under the same conditions (Fig 2D) PhyH was basically stable at 35 °C, and retained 60% ofthe initial activity at 45 °C for 90 when assayed at ... sum of PhyH-DI and PhyH-DII and two times greater than that of PhyHDII This large variance cannot be ascribed tothe function of PhyH-DI alone The dual-domain phytase was shown to be a dimer according ... fused to another single-domain phytase may improve the catalytic efficiency ofthe latter Materials and methods Strains, plasmids and chemicals E coli Trans1-T1 (TransGen, Beijing, China) and pGEM-T...
... usedas template for quantitative RT-PCR analysis The M sexta ribosomal protein S3 (rpS3) mRNA was usedas an internal standard to normalize the amount of RNA template The primer pairs usedare ... representing the proHP8Xa zymogen, a truncated formof proHP8Xa andthe catalytic domain of active HP8 are marked with arrowheads The size and position of molecular weight standards are indicated on the ... ¨ 3¢-RACE and 5¢-RACE to obtain the missing ends ofthe cDNA, and then used primers encompassing the start and stop codons, with larval fat body cDNA as template, to obtain eight individual clones...
... sequence was 5¢-GGAGTCTAATGGACAACTTTNNNTGGATGGA GGGTTATATTGAGCG-3¢, with GAC, CAA and TCA as mutated codons for E451D, E451Q and E451S, respectively DNA sequencing was usedto confirm the incorporation ... ÔeÕ stands for an equatorial hydroxyl anda for an axial one Therefore, the interaction between any residue at position 39 and an equatorial 4-OH was called /4e, and between any residue at position ... interact with E451, whereas the E39 side-chain (Oe atom) may formthe /3 interaction E39 Oe and Q39 Oe atoms may form similar /3 interactions, as glutamate Oe and glutamine Oe atoms have similar...
... AAACATATGCTATATTACAATAAAA GG; 2.2up, AAACATATGTTATCTATCGTTGTAAAGC; 2.3up, AAACATATGCTTGTTCCTCAAAAACTTCC; 3.3rv, AAACTCGAGGACCTTAGCCGTAGTCTTCAC; 3.2rv, AAACTCGAGTTTTCCATTCAAAACCGTG Construction of ... Functional and structural characterization ofthe catalytic domain ofthe starch synthase III from Arabidopsis thaliana Proteins 70, 31–40 Senoura T, Asao A, Takashima Y, Isono N, Hamada S, Ito H ... Construction ofthe pNAL1 vector for the expression of CD of SSIII from A thaliana and truncated proteins The plasmid named pVAL3 containing the catalytic C-terminal domain of SSIII (1374 bp) was used as...
... modification, and only a slight change ofthe rmsd values was observed for the backbone atoms Calculations and statistics Data are expressed as mean ^ SEM Student’s t-test was usedto determine statistical ... support andthe headto-tail cyclization was achieved using orthogonal allyl protection for the a- carboxylic function of aspartic acid (Fig 1) After the last coupling cycle and removal ofthe allyl ... procedure, aspartic acid was attached tothe solid support via the b-carboxyl group whereas the a- carboxylic group was protected as allyl ester Monitoring of peptide deprotection and lactamization...
... and intrarenal vascular tissue decreasing glomerular filtration rates [29], stimulation of apoptosis of immature thymocytes [30] TXA2 has been implicated asa mediator ofa number of vascular disorders ... Subsequently 100 lL ofthe Stop/ Glo Reagent TM was added and luminescence due to renilla luciferase was measured Relative firefly to renilla luciferase activities were calculated asa ratio and were expressed ... Statistical analysis The organization andthe exon-intron boundaries ofthe human thromboxane (TX) A2 receptor (TP) gene andthe theoretical range of putative TP mRNA transcripts are 4062 A T...
... broadband services Furthermore, for technical reasons, because they use far more data and rely heavily on images and sound as opposed to text, broadband services are far more difficult to monitor ... flexibility, and income required to purchase and use personal computers andto obtain access tothe Internet andtothe data and services available on it Contrary to popular belief, however, the primary ... decree, andasa result ofthe settlement the 1984 breakup of AT&T (Interestingly the AT&T case, arguably the most important and aggressive antitrust action in many decades, was both filed and settled...
... equation J Inequal Appl 2011 (2011) Article ID 194394 13 Kenary, HA: On the Hyers-Ulam-Rassias stability ofa functional equation in non-Archimedean and random normed spaces Acta Universitatis Apulensis ... Del Circolo Math Di Palermo (to appear) Kenary, HA, Shafaat, Kh, Shafei, M, Takbiri, G: Hyers-Ulam-Rassias stability ofthe Appollonius quadratic mapping in RNspaces J Nonlinear Sci Appl 4, 110–119 ... Hyers-Ulam-Rassias stability of approximately additive mappings J Math Anal Appl 184, 431–436 (1994) doi:10.1006/jmaa.1994.1211 Skof, F: Local properties and approximation of operators Rend Sem Mat...
... plasmids were usedas controls 2.4 Gel retardation analysis A DNA fragment used for gel retardation analysis containing a sequence from the 5’-untranslated region of GS 1a was obtained by cleavage with ... in all compared organisms We have also analyzed the presence of putative elements in the 5’ region ofthe gene There is a canonical TATA box at –35 bp from the transcription start site anda putative ... facilities ofthe Molecular Biology Laboratory, Research Services, Universidad de Málaga The nucleotide sequence data reported are available in the EMBL, GenBank and DDBJ Nucleotide Sequence Database...
... related to localization and size ofthe EGIST andto evaluate the impact ofthe molecular characterization as an outcome parameter related tothe molecular targeted therapy In absence of these ... report ofa case Surg Today 2006, 36:994-996 Todoroki T, Sano T, Sakurai S, Segawa A, Saitoh T, Fujikawa K, Yamada S, Hirahara N, Tsushima Y, Motojima R, Motojima T: Primary omental gastrointestinal ... abdominal wall and one located between liver and stomach) By means ofa critical revaluation ofthe surgical reports and clinical histories anda careful search for residual muscular tissue from the...
... superior to radiotherapy alone in the treatment of locally advanced anal cancer: results ofa phase III randomized trial ofthe European Organization for Research and Treatment of Cancer Radiotherapy ... SIB to treat the elective areas and gross disease in the same number of fractions IMRT was able to significantly reduce the grade 2+ dermatologic and grade 3+ gastrointestinal/genitourinary events ... performed if physical examination findings were favorable Statistical Analysis The Kaplan-Meier method was usedto calculate and estimate rates of overall survival and freedom from any disease...
... and methods Drosophila strains The strain in which the S character appeared was denominated SimES ; it was already described (C 1980 aand b) A second D simulans , OMENDADOR strain (Madagascar) ... shown to have properties : (i) it was more viable than the original strain and (ii) it retained the S character This last fact allows us to reject the hypothesis ofa fundamental role of these pathogenic ... examples of maternal transmission of characters are known for the genus Drosophila In cases the causal factor appeared to be a microorganism : CO RUN sensitivity is due tothe Rhabdovirus sigma (B...