the quest for their existence after the entry into force of the lisbon treaty
International Humanitarian Law and Human Rights Law Towards a New Merger in International Law
... Examples are the Magna Carta of 1215 the U.K Bill of Rights of 1688, the French Declaration of the Rights of Man and of the Citizens of 1789, the U.S Bill of Rights of 1791 The demand for human ... Rethinking the Conception of the Law of Armed Force, 17 Eur J Intl L 921, 922 (2007) The Geneva Convention for the Amelioration of the Condition of the Wounded and Sick in Armed Forces in the Field, ... merged in the contemporary corpus of IHL.38 The scope of the law of war was related to the other main branch of international law, the law of peace At the beginning of the 20th century, the generally...
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The Role of Genetically Modified Organisms (GMOs) in Beverage Production
... detecting the presence of GM ingredients Unfortunately, standardized methods not currently exist for most of the GM ingredients on the market today Two types of tests are used for the detection of GM ... concerned about the presence of GM ingredients Food manufacturers have been monitoring their 800 numbers for an indication of how their consumers feel about GM foods To date, the number of calls on ... throughout the world bears little resemblance to teosinte, the original ancestor of corn The newer techniques involving genetic engineering, on the other hand, allow for the transfer of a few genes...
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Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf
... turns of the DNA double helix yields binding of the two or three NF-Y complexes on the same side of the DNA Conservation of spacing is required for optimal promoter activity because changing the ... downstream of the E2F-responsive part of SIRF [48] The results of Kidokoro and colleagues have been put into question by a very recent report identifying a p53binding element further upstream in the ... located upstream of the CDE-like site [46] These observations and the fact that activation does not rely on CCAAT-boxes, NF-Y or Sp1 proteins, leave open the question of whether the BUB1B promoter...
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Tài liệu Báo cáo Y học: Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis potx
... rearrangements of the monomer that brings together the glutaminase site and the active site (C) GTP locks the enzyme in the active form for CTP synthesis and thereby stimulates the kcat of the reaction ... that if the role of GTP was solely to increase the rate of glutamine hydrolysis, there would have been no effect of adding GTP when the rate of CTP synthesis was limited by the concentration of nucleotide ... activity was therefore calculated for the experimental conditions used for GTP activation on the basis of the kinetic constants in Table 1, and those obtained for the glutaminase reaction in the presence...
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Báo cáo khoa học: The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase pptx
... segment and the other helix lines the boundary between the major domain and the N-terminus (Fig 1) Therefore, the formation of the third cluster may represent a key event of the final phase of folding, ... extent it does with the other holoforms, although the wavelength of maximum emission is the same for all enzyme forms (Fig 3, insets) In the light of the results obtained from the ultracentrifuge ... to the double mutant holoenzyme (Fig 2) PLP binding properties The affinity of wild-type and mutant forms for the cofactor was measured to evaluate the impact of the mutations on the structure of...
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Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase pdf
... 1B shows that whilst preadipocytes express both GSK3 isoforms, the abundance of the b isoform declines by 85%, whereas that of the a isoform is virtually undetectable in differentiated adipocytes ... establish the importance of GSK3 in the acute regulation of glucose transport in terms of its regulatory control of GS in muscle and fat cells we have investigated the effects of Li and the anilinomaleimide, ... odds with the study of Orena et al [21] in which the authors reported the presence of significant GSK3 activity The reasons for this discrepancy are unclear, but the assay protocol used in the present...
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Báo cáo Y học: Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice usingin vivo 13 C NMR measurements of hepatic carbohydrate metabolism docx
... of the liver of a control mouse acquired using the FLASH sequence (TR ¼ 10 ms, TE ¼ ms) The rectangles indicate the location of the volume of interest, % 400 lL (8.5 · · mm3) The 13Clabeled formic ... activity of the indirect pathway of glycogen synthesis In addition, this study reports for the first time the simultaneous detection of increased signal intensity for the glycogen C2–C5 resonances These ... net synthesis of glycogen or the combination of both The rates of total glycogen synthesis and 13C label incorporation into glycogen (Fig 5) suggest that the overall rate of glycogen synthesis...
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Báo cáo Y học: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase pdf
... substrate The reduced affinity of the mutants for the phenyl moiety of the substrate was also evident from the twofold to 100-fold increased Ki values for PAA From analysis of the kcat values for substrates ... derivatives thereof, while maintaining the hydrophobicity of the binding site To test the effect of the mutations on the specificity for phenylacetylated substrates, the steady-state kinetic parameters for ... mM of the wild-type The results indicate that mutating bF57, which is located ˚ at the bottom of the binding pocket at A from the nucleophilic serine, does influence the rate of formation of the...
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The role of floating-rate bank loans in institutional portfolios pdf
... from a licensed professional These views are subject to change at any time based upon market or other conditions and are current as of the date at the beginning of the document The opinions expressed ... the amount of principal recovered in the event of default (historically, 60%–70%) The historic return profile of the Credit Suisse Leveraged Loan Index changed dramatically following the 2008 financial ... on the riskiness of a loan) The credit spread reflects market price movements The default rate is the default rate of a bank loan portfolio (historically, 2%–3%), and the recovery rate is the...
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Perceptions About Network Security: Survey of IT & IT security practitioners in the U.S. pptx
... 6, there is uncertainty as to where the breaches originate Forty percent of respondents not know the source of the network security breaches Of the 60 percent who say they know the source of ... about the cost is consistent with two other studies Ponemon Institute conducts annually: the Cost of a Data Breach and the Cost of Cyber Crime According to the findings, the average cost of one ... experienced over the past 12 months? No, we not know the source of attacks 40% Yes, we know the source of some attacks 33% Yes, we know the source of most attacks 16% Yes, we know the source of all attacks...
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FUTURE OF THE NUCLEAR SECURITY ENVIRONMENT IN 2015 pptx
... Responsibility for the final content of the papers rests with the individual authors We also wish to thank the following individuals for their cooperation and support, for their assistance in making the ... justification for eliminating these regimes using outside force unless, of course, they commit an act of aggression against some other state Increasing reliance on the use 40 To read the text of the Treaty ... secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility given to the...
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Báo cáo khoa học: The role of Ureaplasma nucleoside monophosphate kinases in the synthesis of nucleoside triphosphates potx
... volume of 20 lL The reaction was initiated by the addition the enzyme (100 ngÆreaction)1 for the determination of NTP synthesis rates and 0.5–1 ngÆreaction)1 for the determination of NDP synthesis ... limitation of dNTP levels for DNA synthesis could be the reason Mollicutes lack the de novo synthesis of purine and pyrimidine bases and have to rely on salvage path1988 ways for the biosynthesis of ... level of incorporation into DNA, but the level of labelled dTTP was very low [18] In organisms where NDK is present, the rate-limiting step in the synthesis of dNTPs ⁄ NTPs is not the conversion of...
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Báo cáo khoa học: Role of peroxidase inhibition by insulin in the bovine thyroid cell proliferation mechanism pdf
... the four mixtures of solvents then used for the elution After seeding the sample, the elution was made in the following order of increasing polarity: (a) Fifty mililiters chloroform/methanol 19:1 ... On the other hand, the absence of the inhibitor in free follicle cultures, may be due to the lack of cellular proliferation, absent in this type of culture These facts support the hypothesis that ... duplicate plates of silica gel 60 on polyester The developing solvent consisted in a mixture of chloroform/ methanol/0.2% calcium chloride [60 : 40 : (v/v/v)] After drying the plates, one of them was...
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báo cáo hóa học: " The role of cumulative physical work load in symptomatic knee osteoarthritis – a case-control study in Germany" potx
... Calculation of the power of the study was based on an expected prevalence of kneeling of 9% among the male population according to Seidler et al [8] To detect an odds ratio of 2.0 with a power of 80% for ... in the Frankfurt Institute for Occupational Medicine, according to the Classification of the Federal Statistical Office Germany (STBA) [7] Major occupations were a priori formed on the basis of ... not informed of the specific aims of the study They were asked to participate in a study concerning the theme 'occupation and health' Exposure assessment Job titles were coded blind to the case-control...
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báo cáo khoa học: "The role of 18F-FDG-PET/CT in the preoperative staging and posttherapy follow up of gastriccancer:Comparison with spiral CT" docx
... accepted the cut off SUVmax value as 2.5 in their study at which the role of PET/CT was investigated, and they found out the Page of sensitivity of the technique 40% [12] In our study, because there ... tests The subjects were divided into three groups 4/42 of the analysed scans were performed for preoperative staging (group 1), 30/42 of the for posttherapy restaging (Group 2) and 8/42 for recurrence ... [17] The guideline also recommends PET for evaluation of therapy response and to make the decision of continuing the ongoing therapy or stopping and redirecting the patient to other salvage therapies...
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Báo cáo y học: "The role of T cell interleukin-17 in conducting destructive arthritis: lessons from animal models" pps
... [27,28] These studies indicate the existence of an IL-23/IL-17 axis of communication between the innate and adaptive parts of the immune system that might be an interesting target for the immunotherapy ... IL-17R [18] (Table 1) The expression pattern of these new receptors seems to be more cell/tissuespecific than that of the IL-17R, and the ligand specificities of many of these receptors have not ... increased after the onset of CIA [41] Early neutralization of endogenous IL-17 using the IL17 receptor IgG1 Fc fusion protein starting after the immunization protocol during the initial phase of arthritis...
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Báo cáo y học: "The role of tumor necrosis factor-alpha in systemic lupus erythematosus" pdf
... still limited, Page of (page number not for citation purposes) there are a minimum of 28 cases reported at least in abstract form [56-61] and most of these are on the use of the chimeric monoclonal ... all of whom went into complete remission within days after the first (approximately mg/kg) infusion of infliximab [56] Similar to RA, this effect lasted for about weeks after the last infusion of ... observations on the long-term presence of anti-dsDNA antibodies before the onset of SLE symptoms [68] Third, the pronounced anti-inflammatory effects of infliximab may have prevented damage despite the presence...
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Báo cáo y học: "Role of hypoxia-inducible factor 1alpha in the integrity of articular cartilage in murine knee joints" potx
... helices The hydroxylation of proline residues is essential for the formation of intramolecular hydrogen bonds and contributes to the stability of the triple-helical conformation [34] The intracellular ... compartment were assessed for degenerative changes of the articular cartilage, for osteophyte formation and for synovitis In the control joints, the administration of the control solution (1% ... loss of tissue (Figure 2d) Luxation of the patella or other defective positions of joint structures was not observed The analysis of the synovial membrane revealed slight thickening of the synovial...
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Báo cáo y học: " Role of taurine on acid secretion in the rat stomach" ppsx
... slices of the rat stomach Samples were incubated at 37°C for 30 before the addition of taurine were treated within for the production of cAMP Each column represents the mean ± SEM of the percent ... plexus of the enteric nervous system in the stomach Taurinergic neurons in the muscle layer of the gastrointestinal (GI) tract might be involved in motility of the GI tract and the function of endocrine ... replaced by a mixture of 95% O and 5% CO One hour after equilibration of the organ, the mucosal saline solution was replaced every 15 during the experiment Only the serosal side of the preparation...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25