the principles of hematology
Báo cáo y học: "TPO, but not soluble-IL-6 receptor, levels increase after anagrelide treatment of thrombocythemia in chronic myeloproliferative disorders"
... reduction of the platelet count with at least 50 % of the baseline value, and treatment failure (F) as a reduction of the platelet count with < 50 % of the baseline value Here, and for the purpose of ... if therapy for thrombocythemia affects TPO levels, we assessed the effects of months of anagrelide treatment of thrombocytosis in MPD patients on serum levels of TPO and the sIL-6 receptor The ... target cells It is well established that serum levels of TPO are regulated by the binding of the ligand to the receptor and the endocytosis of the ligand-receptor complex [9] Against that background,...
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Tài liệu TREATMENT OF EATING DISORDERS ppt
... Associate Professor of Clinical Nursing at the University of Rochester School of Nursing, a Clinical Associate Professor in the Department of Psychiatry at the University of Rochester School of Medicine, ... is the dance/movement therapist for The Renfrew Center of Florida She is a trustee of the Marian Chace Foundation, a past president of the American Dance Therapy Association, and a past Chair of ... messages from the culture and made I BRIDGING THE GAP: THE OVERVIEW 14 A PERFECT BIOPSYCHOSOCIAL STORM them their own? How can we best increase their awareness of the power of the sociocultural...
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Tài liệu Gynecological and obstetrical manifestations of inherited bleeding disorders in women docx
... for the attachment of the placenta to the uterus [57] Thus, deficiency of FXIII-A at the site of implantation will adversely affect fibrin-fibronectin cross-linking, resulting in detachment of the ... women with VWD, therapy should start on the first or second day of menses, with the specific therapeutic choice, dose, duration of therapy, and therapeutic monitoring Haemostatic therapy includes ... resulting in the loss of embryo [58] In conclusion, on the basis of the mouse model, the absence or a significant decrease in maternal fibrinogen is sufficient to cause rupture of the maternal vasculature...
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Tài liệu Male Reproductive Health Disorders and the Potential Role of Exposure to Environmental Chemicals pdf
... some of the weaknesses and problems that can affect the quality of studies investigating the potential causes of cryptorchidism and hypospadias Quality assessment of the various studies and of the ... edge of the glans or to the top of the penile shaft In moderate cases the meatus is located lower down the shaft and in severe cases lower still and perhaps even in the perineal region, the latter ... largely inaccessible for evaluation of the fetus and of the fetal testis, even if study of the mother (her 16 Male Reproductive Health Disorders and the Potential Role of Environmental Chemical Exposures...
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Tài liệu Diseases and Disorders: Brain Trauma docx
... proportional to the number of bouts engaged in by the victim The more the number of bouts, the greater the likelihood of enduring brain injury.34 Of course, there was nothing carefree about the Quarry ... coordination, lightheadedness, loss of balance, What Is Brain Trauma? 13 This illustration shows the stages of an axon shear The axon is a fiber that extends from the nucleus of the cell loss of memory, ... others Some patients exist in these states indefinitely; others stay alive only with the help of ventilators or other artificial life support Punch Drunk Two of the most well known examples of...
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Tài liệu Diseases and Disorders Acne docx
... swelling, pain, and the presence of pus are all characteristics of inflammation, which in the case of acne appears on the skin in the form of papules, pustules, and cysts, other types of acne lesions ... reduce the body’s response to stress At the same time, the tapes often offer soothing background sounds such as the sound of the ocean or a gentle rain, which help listeners clear their minds of ... occurs on the parts of the body that have the largest sebaceous glands, such as the face, chest, neck, shoulders, upper back, and buttocks The result is the development of one type of acne lesion...
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Tài liệu THERAPEUTICS of PARKINSON’S DISEASE and OTHER MOVEMENT DISORDERS docx
... model of parkinsonism Proceedings of the National Academy of Sciences, of the United States of America, 102, 2174 2179 1: THE ETIOPATHOGENESIS OF PARKINSON’S DISEASE: BASIC MECHANISMS OF NEURODEGENERATION ... rigidity and akinesia, there is no correlation between the clinical severity of PD tremor and the severity of the dopaminergic deficit in the striatum or the clinical progression of the disease (Deuschl ... Careful analysis of the correlation between the clinical symptoms and the extent of the lesion led to the conclusion 27 that experimental rest tremor is the result of damage to the nigro-striatal...
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Tài liệu Molecular Neurobiology of Alzheimer Disease and Related Disorders doc
... with a history of AD [23] Furthermore, at the acute stage of cerebral infarction in the area of the middle cerebral artery, PS2V was detected in the region of the penumbra around the ischemic core ... cotransfection of another U1 snRNP protein, U1-A We demonstrated that the HMGA1a binding site of PS2 pre-mRNA exists in the upstream of the 5Ј splice of the exon Therefore, it is plausible that the strong ... VII Foreword The dawn of psychogeriatrics in Japan was celebrated with the symposium entitled ‘Psychiatry for the Elderly’ in the frame of the annual meeting of the Japanese Society of Psychiatry...
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Tài liệu SLEEP-RELATED BREATHING DISORDERS EXPERIMENTAL MODELS AND THERAPEUTIC POTENTIAL docx
... recorded The commutator allows 3608 rotation of the lower half of the unit while the upper half remains fixed The commutator is placed directly above the center of the cage When telemetry is used, the ... tuned to the low end of the AM dial Passing a battery close to the animal’s abdomen turns on the transmitter, and the unit is turned off between experiments The EEG and EMG signals from the commutator, ... with these efforts, tools of modern molecular biology and functional neuroanatomy have increasingly been applied to investigate the neurobiology of sleep and respiration The synthesis of these...
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Tài liệu Perspectives on Diseases and Disorders Malaria doc
... that must be treated in the hospital The type of drugs, the method of giving them, and the length of the treatment depend on where the malaria was contracted and how sick the patient is For all ... identified since 1969 Symptoms of Malaria The amount of time between the mosquito bite and the appearance of symptoms varies, depending on the strain of parasite involved The incubation period is usually ... evidence of only one cat drop According to the April/June 2005 issue of the Quarterly News of the Association of Former WHO Staff, the flight manifest from a March 1960 delivery mission by the Royal...
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Tài liệu RESPIRATORY CONTROL AND DISORDERS IN THE NEWBORN doc
... properties of these neurons are also very critical in shaping the output of the network itself, irrespective of the properties of the respiratory network as a whole Although the exact nature of how these ... pathogenesis of these apneas may relate to the clinical condition of the patient at the time of the apneas, associated cardiovascular (systemic or pulmonary) changes, the chronicity of the clinical ... in the body, the carotids I will show that there are major differences between the newborn and the adult vis-a-vis the response of the carotids to low O2 and with respect to the ` importance of...
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Tài liệu Parkinson’s Disease and Related Disorders docx
... representation of the state-action matrix in the actor part of the basal ganglia networks is achieved by decorrelation of the spiking activity of the pallidal neurons (output stage of the basal ganglia) The ... project to the motor portion of the striatum (the putamen) with relative sparing of other striatal areas The magnitude of the behavior- al effect of SNc lesions is explained by the fact that the basal ... et al., 2003a) of pallidal neurons in the normal monkey revealed lack of correlation between the spiking activity of these neurons The complex anatomy of the basal ganglia and the physiological...
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Tài liệu Diseases and Disorders of Finfish in Cage Culture doc
... exchange, thereby causing stress to the fish due to low oxygen and accumulated wastes The rate of fouling depends on the mesh size of the nets, temperature of the water and productivity of the site ... parts of the world the primary source of animal protein for humans is finfish The intensive culture of finfish has grown significantly since the 1980s partly because of the dramatic decline in the ... it is also important to consider the rate of biofouling and the species composition of the marine fauna in and around the potential site (Chua, 1982) A checklist of 20 Z:\Customer\CABI\A4337 -...
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Tài liệu Intracellular Traffic and Neurodegenerative Disorders pptx
... phenotype of the respective SPP/SPPL family member (Krawitz et al 2005) The formal proof of the requirement of the aspartate within the YD motif of SPPL family members is still missing The glycine ... al 2007; Weihofen et al 2003) and are likely to also block the members of the SPPL family, since the active site of the GxGD proteases is highly conserved Therefore, the development of selective ... finally remove the TMD from the cellular membranes FAD-associated mutations affect the kinetics of these intramembrane cleavages In the case of APP processing specifically, the production of the benign...
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Tài liệu PEDIATRIC NASAL AND SINUS DISORDERS doc
... attracting the love of a woman Today we still recognize the esthetic significance of the nose, but also—and perhaps more important—we now acknowledge and appreciate the functional significance of the ... comprehensive review of the physiology of the nose, and of its disorders, but also established the relationship between the nasal and the bronchial airways in health and disease The data presented ... significance of the interaction of the nasal airways with the lower airways In fact, because of the similarities between the nasal and bronchial mucosa, the concept of “one airway, one disease”...
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Tài liệu Diseases and Disorders AIDS doc
... relieve the suffering of HIV patients; their symptoms continued, irrespective of confirmation from the blood test that they only carried the virus In fact, the test was often detrimental to these ... blood for the presence of the virus The Origins of an Epidemic 23 AIDS-infected blood, the statistics were terrifying to the public In the final weeks before blood banks began using the HIV test ... that the flu-like symptoms that are the hallmark of initial HIV infection are the results of the body’s initial attempt to battle the virus In this stage, referred to as the acute stage of infection,...
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Tài liệu Diseases and Disorders Sexually Transmitted Diseases doc
... and other diseases wherever they go Air travel has increased the spread of STDs immeasurably by transporting infected people from one side of the globe to the other in a matter of hours The fact ... occur in the United States alone, a rate of new infection higher than that of any other country in the industrialized world Indeed, the CDC, the federal agency that monitors the incidence of disease ... since the invention of the birth control pill in the late 1950s made pregnancy a much less likely result of sexual relations and helped to launch the so-called sexual revolution of the 1960s For the...
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Tài liệu Diseases and Disorders: Autism doc
... They seem deaf to the speech of others and may not even turn to the sound of their names When they are babies, they not babble, imitate words, nor smile at their parents As they grow older, they ... memory, too All of these parts of the brain interact with one another or are wired to and communicate with each other through the white matter The lobes of the brain: the frontal (blue), the parietal ... is the outer layer of the brain The brain as a whole is divided into two halves, or hemispheres Within the hemispheres are the four lobes The frontal lobes are at the very front of the brain They...
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Tài liệu MENTAL DISORDERS - THEORETICAL AND EMPIRICAL PERSPECTIVES docx
... another job as good as the one he lost, the therapist had the patient list the elements of the ideal job, The therapist then had the patient compare his previous jobs with each element of the ... strong), the patient rates the rest of the items The severity of the suicidal ideations are calculated from the first 19-items and the range of scores is from 0-38 There is no cut-off score, but the ... of rescue Items 9-15 focus on the attempter’s perception of the lethality of the attempt, expectations of rescue, degree of premeditation, and the purpose of the attempt Items 16-20 include the...
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Tài liệu DISEASES AND DISORDERS A Nursing Therapeutics Manual THIRD EDITION pdf
... dilation of the arterial wall in the latter portion of the descending segment of the aorta Aneurysms of the abdominal aorta occur more frequently than those of the thoracic aorta AAAs are the most ... determine the point of impact, the distance of the fall, and the type of landing surface If the patient has been shot, ask the paramedics or police for ballistics information, including the caliber of ... occurs when the uterus retains parts of the products of conception and the placenta Sometimes, the fetus and placenta are expelled, but part of the placenta may adhere to the wall of the uterus...
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