... through the inhibition of APCs or pathogenic T cells, by maintenance ofthe TR cell population and/or by enhancementof their function (reviewed in [54]) Elucidation ofthe mechanism of TR cell ... anti-tumour or microbial immuneresponses A strategic manipulation of TR cells might thus be used either to enhance or to dampen immuneresponses as required The identification of molecular markers, ... cells: their role in the control ofimmuneresponses Transplantation 2003, 75:8S-12S 50 Asseman C, Mauze S, Leach MW, Coffman RL, Powrie F: An essential role for interleukin 10 in the function of...
... pre-clinical assessment ofthe efficacy of a Listeria vaccine in the induction ofimmuneresponses against HIV Journal ofImmune Based Therapies and Vaccines 2011 9:2 Page of Submit your next manuscript ... above the mean Page of compared to the sera of naïve monkeys No increases were observed during the course ofthe immunization in any monkeys (Table and 2) We also screened for anti-Gag IgG responses ... prime-boost Furthermore, the lack of detectable anti-Gag antibodies and low anti-Lm titers, while not unexpected, could be increased by the selection of boost modalities The potential benefits of live-vector...
... concert to maintain the integrity oftheimmune system Cells oftheimmune system originate from their hemapoietic progenitors in the bone marrow Some cells leave the bone marrow after they were created, ... migrate to other sites such as the thymus and mature into effector cells Many oftheimmune cells mature in the bone marrow before migration to their respective sites in the body where they guard ... stronger response towards the invading pathogen Hence, the host is protected from the invading foreign microorganisms via the effective interplay ofthe both arms in theimmune system 1.2 Innate...
... Group ofthe University of Valladolid History of evaporative cooling Many examples ofthe application ofthephenomenonof evaporative cooling can be found, such as the metabolic regulation ofthe ... temperature through the evaporation of sweat from the skin, the use of cooling towers or evaporative condensers, the cooling of pools by the evaporation ofthe water, etc Furthermore, it was the most widespread ... distributions [7] As the main resistance to heat-transfer can be found in the air on the dry face ofthe system, the advantage ofthe higher thermal conductance of metals than that of plastics is negligible...
... phenomenonof science among the other phenomena ofthe world and reveals the significance of science in the overall picture ofthe evolution ofthe universe That is how the plan of this book arose How ... consider the continuous method of data transmission The content ofthe message will be the amount of voltage applied to the wire at its beginning Owing to noise, the voltage at the other end ofthe ... concepts of “segment” on the first level and the concept of “polygon” on the second The concept of “house” comes on the third level By the concepts of “segment” we mean the aggregate of concepts of...
... Page of 10 (page number not for citation purposes) to 12) The median ofthe assessment based on the BILAG index [16] was (range to 13) Meanwhile, the median ofthe total white blood cells for the ... molecules in the networks As most ofthe genes in theimmune response were TNF regulated, we performed stimulating experiments on the PBMCs of SLE patients and healthy individuals to assess the TNF ... individuals to assess the TNF regulation on theimmune response-related molecules in SLE On the other hand, although the expression of IFN was Gene expression profiles of peripheral blood mononuclear cells...
... the proliferation oftheimmune cells In the present study, we also demonstrated that the in vivo overexpression of hIL-32β resulted in the exacerbation of other mouse models of TNFα-related diseases ... complementary to the unique sequence of hIL-32β, because IL-32β is the dominant secreting isoform of IL-32 This probe could detect the cDNA of hIL32β and IL-32γ, but not of IL-32α or IL-32δ, by Southern ... observed in histological examination ofthe spleen, the joint, the intestine, the kidney, and the liver (data not shown) We next examined the response of splenocytes of BM-hIL-32 mice to LPS stimulations...
... Page of 10 (page number not for citation purposes) to 12) The median ofthe assessment based on the BILAG index [16] was (range to 13) Meanwhile, the median ofthe total white blood cells for the ... molecules in the networks As most ofthe genes in theimmune response were TNF regulated, we performed stimulating experiments on the PBMCs of SLE patients and healthy individuals to assess the TNF ... individuals to assess the TNF regulation on theimmune response-related molecules in SLE On the other hand, although the expression of IFN was Gene expression profiles of peripheral blood mononuclear cells...
... pair of nodes [43] Conclusion The simple models developed to study parts oftheimmune system decipher parameters that reveal the regulation ofimmuneresponses and allow us to extrapolate the ... the model can parameterize the continuous change ofimmune components as a function of time The model reveals specific parameters defining the dynamics ofthe host’s immune processes that are ... minimize the uncertainty about the behavior between the observations The availability of frequent measurements for all or almost all theimmune components one wants to model facilitates the use of...
... coincidentally, the properties ofthe former are reminiscent ofthe properties of mature, differentiated cells, whereas the properties ofthe latter are reminiscent ofthe properties of young, differentiating ... ofthe apparent absence of active sources of CH and NH before the origin of life and the instability of methane and ammonia under UV irradiation On the other hand, if the aforementioned hypothesis ... of energy/ matter forms, and so forth, with the ultimate purpose being the perpetuation and expansion of living matter as a whole On the origin of life Addressing the question ofthe origin of...
... terms ofthe extent of knowledge of slang, the frequency of using slang, the reasons for not using slang, when to use slang, the feelings ofthe students about slang and the opinions towards the ... know many ofthe statements involved in thephenomenonof Vietnamese equivalent of English 4.2 Frequency of using slang 12 The chart below describes the frequency of using slang ofthe students ... introduce them to their friends to broad the knowledge of slang As a result, they know hundreds of slang However, the students at Cao Ba Quat High School not know many of them, most ofthe students...
... A is the coordinate ofthe mass m The inductance u x ) ofthe coil in the electrical circuit R-L-C is a variable quantity depending on the position A ofthe mass m swinging F ig under the coil ... when the frequency ofthe electrical circuit is equal to half the natural frequency ofthe vibrator, there exists an interval of frequencies, in which the mass m vibrates strongly with the frequency ... which is parallel to the axis a and cuts the resonant curve, and crosses from the region w < to the region w > , then, at the point of intersection ofthe straight line with the resonant curve...
... STUDY OFTHEPHENOMENONOF GHOSTS WHO ACQUIRED GODHOOD FOLLOWING UNNATURAL DEATHS: ZHIGUAI TALES FROM THE SIX DYNASTIES 何璇 HE XUAN 新加坡国立大学中文系 硕士学位论文 A THESIS SUBMITTED FOR THE DEGREE OF MASTER OF ... regulation and local policy At the same time, literati in the Six Dynasties also greatly contributed to the spread ofthe stories Furthermore, this thesis focuses on studying the interactions between ... cause great disasters Their behavior and image contradict the traditional concept of a god, who must be both righteous and merciful This thesis seeks to explain the process of how ligui ghosts...
... (66%) of them of both sexes having been informed ofthe results ofthe tests and thus being aware of their status Overall, nearly two-thirds ofthe respondents (64%) reported having changed their ... addressing the immediate concerns of companies in the wake ofthe pandemic As they stand, however, they are neither creative nor far-reaching in their orientation The progressive nature ofthe disease ... because ofthe 3-month strike in the private security sector that coincided with the start ofthe project It is possible that several ofthe smaller security firms closed as a result ofthe impact of...
... that the value of one year of human life is equivalent to the value of per capita South Africa's GDP in the year of that human life That is, the value of one year of human life is equivalent to the ... efforts ofthe South African Government and the initiation of PEPFAR after the announcement ofthe comprehensive plan Less than half ofthe people requiring ARVs are currently receiving them Some of ... based (as is the case for any asset) on the future returns it will earn In the human case, these returns are earnings Hence, the value of a life is the present value ofthe stream of expected...
... by inconsistent responses when either the mean of true responses differ from that ofthe random/fixed responses or all items in the scale have the same polarity The inflation in the former situation ... contrast to the other two scales, the presence of both random and fixed responses would reduce the Cronbach’s alpha ofthe MH scale Thus, the reported Cronbach’s alpha of 0.33 is indeed the minimum ... to minimize the impact of inconsistent responses However, the choice ofthe number of response categories may largely depend on the actual content ofthe scale [10] Modern assessment of item characteristics...
... encoding the structural proteins of RVFV The elicited immuneresponses towards the N, GN, GC and GN/GC proteins after gene-gun immunisation were analysed and the protective abilities ofthe N and the ... containing the open reading frame ofthe GN/GC poly-protein and two groups, each containing four animals, were immunised with either the GN or the GC construct To analyse theimmuneresponses ... NaCl The PRNT50 titer was calculated as the reciprocal ofthe highest serum dilution that reduced the number of plaques by 50%, as compared to the virus control Statistical methods The outcome of...
... apoptosis of CD4-positive cells In the first set of experiments, the amount of infectious virus was increased two-, four-, and eight-fold higher and the ability of a constant amount of engineered ... cultures in the presence of either HIVMN [Table 3: 2(b)] or HIV-Ba-L [Table 3: 2(c)] infection The increase in the percentage of CD4 is accompanied with a decrease in the percentage of CD8 positive ... 3-days The cells were then removed, the wells washed, and the viral antigen coated wells were assayed for the presence of human antibodies Detection was accomplished by monitoring the binding of...
... merging ofthe results For clarity of presentation of results, sometimes only the results for a single dengue serotype will be shown in the main text ofthe thesis, whereas the results ofthe other ... What is the relevance and the effect of viral diversity to identification of targets ofimmune responses? How vaccine developers deal with the increasing diversity of targets ofimmuneresponses ... knowledge of pathogenesis and oftheimmuneresponses elicited by dengue viruses emphasise the crucial role oftheimmune system in the control of infection (Rothman, 2004) Understanding the interactions...