the phantom of the opera 2004 official site
The phantom of the opera
Ngày tải lên :
20/03/2014, 16:12
... through the
opera, and after the opera. But they talked very quietly, and
they looked behind them before they spoke.
When the opera finished, the girls went back to their
The directors of the Opera ... &apos ;The ghost killed him!'
The directors of the Opera House
The Opera House was famous, and the directors of the Opera
House were very important men. It was the first week of work
for the ... he has the head of a dead man,
with a yellow face and no nose. People hear a voice in
another room, but the room is empty.
It is the Phantom of the Opera . . .
12 The Phantom of the Opera...
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Báo cáo khoa học: Structure of the complex of a yeast glucoamylase with acarbose reveals the presence of a raw starch binding site on the catalytic domain doc
Ngày tải lên :
07/03/2014, 12:20
... at the
opposite end of the barrel to the active site has weaker
electron density and the temperature factors of the
atoms in this segment are 31 A
˚
2
, 2.35 times above
the average B for the ... formed
between the enzyme and Tris are the same as observed
previously [16].
In the Glu-A complex there are two acarbose mole-
cules: one in the active site and the other on the sur-
face of the enzyme ... at the active site and the
second at a site remote from the active site, curved around Tyr464 which
resembles the inhibitor molecule in the ‘sugar tongs’ surface binding site in
the structure of...
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Báo cáo khoa học: The enantioselectivities of the active and allosteric sites of mammalian ribonucleotide reductase pptx
Ngày tải lên :
07/03/2014, 17:20
... at these two sites reflects conservation of the
known triphosphate and base interactions, with
decreased affinity mainly resulting from loss of the
interactions with the ribose, e.g. in the s -site, ... as
allosteric sites. We have recently demonstrated that
there are three such sites in murine R1 (mR1) (the
specificity or s -site, the adenine or a -site, and the
hexamerization or h -site) [2,3], ... Lineweaver–Burke plot of
L-ADP
inhibition of dGTP-dependent
D-ADP reductase in the presence of 2 mMD-ATP. (B) Secondary plot of the slope values of A. (C) Lineweaver-
Burk plot of
L-ADP inhibition of dGTP-dependent...
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Báo cáo khoa học: Carbohydrate binding sites in Candida albicans exo-b-1,3-glucanase and the role of the Phe-Phe ‘clamp’ at the active site entrance ppt
Ngày tải lên :
15/03/2014, 23:20
... glucose of the b-
glucan substrate in the )1 subsite at the bottom of the
active site pocket [20]. The entrance to the active site
pocket of Exg is flanked by a pair of phenylalanyl resi-
dues, Phe144 ... the Phe144:Phe258 pairing that lines
opposite sides of the entrance to the pocket was partic-
ularly relevant because it largely defined the +1 sub-
site. Indeed, the importance of the +1 subsite ... implemented
to help explain their importance to the specificity and
catalytic efficiency of the enzyme.
The role of the Phe-Phe entranceway
The fortuitous discovery of an unreacted molecule of
the mechanism-based...
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Báo cáo khoa học: Probing the mechanism of the bifunctional enzyme ketol-acid reductoisomerase by site-directed mutagenesis of the active site pot
Ngày tải lên :
16/03/2014, 18:20
... first in the presence of the inhibitor IpOHA [8]
and later with product bound in the active site [9].
There are several interesting features revealed by these
structures. First, the active site contains ... organization of this enzyme is substantially
different from that of the spinach enzyme with the
active site constructed from two monomers of a dode-
camer. In contrast, the active site of spinach ... or cofactor and in these cases
the concentration of the nonvaried components were
increased so that they would be at least 90% saturating.
For the varied component, a preliminary estimate of the
half-saturating...
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WORKING PAPER SERIES NO. 393 / SEPTEMBER 2004: THE DETERMINANTS OF THE OVERNIGHT INTEREST RATE IN THE EURO AREA doc
Ngày tải lên :
22/03/2014, 23:20
... increase the
expected rate and therefore also the current interbank rate, but the amount of the increase
depends on both the size of underbidding and the slope of the demand curve. There is
then ... move the
interest rate up to the level expected to prevail at the last day of the maintenance period.
The level of the interest rate at the last day depends on the slope of the demand curve and
the ... assumed, rather they come from the first order conditions of the theoret-
ical model, representing optimizing beha vior of agents. Recall that at the last day of the
maintenance period the aggregate...
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Official Report of the Exploration of the Queen Charlotte Islands for the Government of British Columbia doc
Ngày tải lên :
23/03/2014, 08:21
... Report of the Exploration of the Queen Charlotte Islands
26
shore, when near the mouth of Tlell River. The general elevation of
the eastern is much higher than that of the northern shore of the ... extreme
southern village of the Hyda nation, familiar with the shores of the
southern portion of Moresby, and also of Provost Island, and the
other of Gold Harbor, well acquainted with the northwestern ... interior
beyond the range of the human eye, when standing upon the
Official Report of the Exploration of the Queen Charlotte Islands
45
Kowing, Kulin, Kitzhaun and Kuk. They have their source...
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Official Report Of The Exploration Of The Queen Charlotte Islands For The Government Of British Columbia (dodo Press) By Newton H. Chittenden potx
Ngày tải lên :
23/03/2014, 10:21
... extreme
southern village of the Hyda nation, familiar with the shores of the
southern portion of Moresby, and also of Provost Island, and the
other of Gold Harbor, well acquainted with the northwestern ... by the sinking of the earth’s
surface, and the inflowing of the waters of the ocean, forming the
most remarkable labyrinth of inlets, sounds, straits, channels and
passages on the face of the ...
parties of prospectors and others have visited various parts of the
islands, no systematic effort has hitherto been made for the
exploration of the entire group.
Under the direction of the Dominion...
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Báo cáo khoa học: Site-directed mutagenesis and footprinting analysis of the interaction of the sunflower KNOX protein HAKN1 with DNA ppt
Ngày tải lên :
23/03/2014, 13:20
... calculate the position of the footprint. Letters to the right of each
panel indicate the DNA sequence (5¢ end in the upper part) of the corresponding strand in this region. In the lower part, the sequence ... to the right of each panel indicate the DNA sequence (5¢ end in the upper part) of
the corresponding strand in this region. Below the footprints, the sequence of the corresponding binding site ... towards the 3¢ end of the top
strand and the 5¢ end of the bottom strand (Fig. 4B).
This agrees with the presence of a larger residue that
makes stable contacts with this region of DNA.
The interaction...
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Báo cáo Y học: The presence of phosphate at a catalytic site suppresses the formation of the MgADP-inhibited form of F1-ATPase potx
Ngày tải lên :
24/03/2014, 00:21
... P
i
[18]. Here we
examined the effects of P
i
on the formation of the MgADP-
inhibited f orm o f the a
(W463F)3
b
(Y341W)3
c subcomplex. The
extent of ADP inhibition of the a
(W463F)3
b
(Y341W)3
c ... ADP binding. The other
is that P
i
binds to a site o ther than any of the catalytic sites.
In the ®rst case, it is possible that P
i
binding interferes in
ATP binding, because of the c phosphate. ... binding to the catalytic sites was
monitored b y ¯uorescence quenching of the introduced
tryptophan residues in the presence of P
i
. The time course of
the ¯uorescence quenching on addition of MgATP...
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