the interaction between redox and hypoxic signalling pathways in the dynamic oxygen environment
Báo cáo sinh học: "Genetic interaction between sire and population of mates in Drosophila melanogaster" pps
... number, and placed in separate numbered vials with females each of their own and the tester strain After d the males were discarded and the females placed in pairs of similar strain into laying vials ... compared with the heritability of crossbred performance (h!) The parameters the different means by which the interaction may be in one case, as a change in the ranking of sires, or in another, as ... Should the interaction be absent, or insignificant, then selection within the purebred may be regarded as the method of choice When the genetic interaction is not significant, most of the gene...
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Tài liệu Báo cáo khoa học: A kinetic model of the branch-point between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana doc
... threonine biosynthesis pathways in Arabidopsis the following procedure was used Firstly, the kinetic links inside the branch-point and between the branch-point system and the rest of the pathway ... for the branch-point between the methionine and threonine biosynthesis pathways in the plant was the qualitative model shown in Fig The allosteric interaction of TS with AdoMet was observed in ... threonine biosynthesis pathways In the following the model is used to investigate the sensitivity of the two-enzyme system to the different input variables and to explain the behaviour of the branch-point...
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Tài liệu Báo cáo Y học: Role of electrostatics in the interaction between plastocyanin and photosystem I of the cyanobacterium Phormidium laminosum ppt
... DISCUSSION To our knowledge, the work described here and in the related publications [1,7] is the first kinetic analysis of the in vitro interactions Cyt f–plastocyanin and plastocyanin– Fig Comparison ... Table in [7] and Table in this paper) In what follows we summarize the expected contributions of binding and electron transfer to DHà and DSà and estimate their relative importance in the light ... (as is the case for the analogous residue in Anabaena sp PCC 7119, R88 [15]) and if the interaction with photosystem I is the reason for having acidic residues in the interface (especially the better...
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Báo cáo khoa học: Relationships between the ethanol utilization (alc ) pathway and unrelated catabolic pathways in Aspergillus nidulans pptx
... pathway in A nidulans [40] Even if L-isoleucine and L-valine are degraded in A nidulans as they are in yeast, then the formation and conversion of the L-leucine Ó FEBS 2003 Activation of alc genes in ... 3559 Fig The branched-chain aliphatic amino acids L-valine and L-isoleucine not induce the alc system Transcript analysis was performed in a wild-type strain Induced mycelia were grown in the presence ... the utilization of putrescine [47], we could confirm that the diamine needs to be converted into the corresponding aldehyde to induce the alc genes; putrescine does not induce the alc system in...
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The interaction between climate and the processing of coated papers in printing and finishing pot
... The situation in paper production and printing industry ˿ The situation in printing and finishing industry ˿ Circumstances in the workshop ˿ Paper handling 11 ˿ ˿ ˿ ˿ Blistering Breaking in the ... tearing in the internal structure of the paper and blistering in the printed areas (see figures) binding agents and coating pigments used, the amount of binding agents contained in the paper and ... bars and the former fold, causing the print to smear and preventing successful processing in the folding unit Two-sided printing in a printing unit Heatset inks settle (or “set”) when the thin-liquid...
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Báo cáo y học: "The aryl hydrocarbon receptor-mediated disruption of vitellogenin synthesis in the fish liver: Cross-talk between AHR- and ERα-signalling pathway" ppt
... also interact with the ARNT via their ligand-binding domains and activate the target genes This kind of interaction is E2-dependent and involves physical interaction of the ERs with C-terminal ... shown to inhibit several estrogeninduced responses in the rodent uterus, mammary gland and in the mammalian cell cultures (reviewed in [12,13]) The cross-talk between the ERα and AHR signalling pathway ... incorporated into the developing oocyte by receptor-mediated endocytosis [3,4] and processed into three smaller proteins: phosvitin, a phosphorus containing protein, and two lipid containing proteins,...
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Báo cáo y học: " Interactions Between Estrogen- and Ah-Receptor Signalling Pathways in Primary Culture of Salmon Hepatocytes Exposed to Nonylphenol and 3,3'''',4,4''''-Tetrachlorobiphenyl (Congener 77)" ppsx
... XRE sequences in the promoter regions of the target genes to regulate their expression Conclusion The findings in the present study demonstrate the interactions between NP and PCB-77 in primary ... (E2)-induced hepatic synthesis of egg yolk protein (Vtg) and eggshell protein (Zr-protein) precursor, respectively, their secretion and transport in blood to the ovary and their uptake into maturing ... significantly increased in the combined PCB-77 and NP exposure group, compared with NP exposure alone (Fig 4F) Discussion In the present study, we investigated the ER-AhR interactions and their mediated signalling...
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The mechanism of action of sprouty2 characterization of the interaction between sprouty2 and PKCdelta
... (EVH) domain in the Nterminus, a Cys-rich domain very similar to that of Spry in the C-terminus, and a central domain that mediates the binding to KIT, the KIT-binding domain (KBD) (Kim and BarSagi, ... (Raf kinase inhibitor protein) Rather than interfering with the catalytic activity of kinases in the pathway as in the case of the phosphatases, RKIP binds to both Raf and MEK and prevents their ... contained in the N-terminal CR1, and binds to GTP-bound Ras with high affinity In addition to the RBD, CR1 also contains a Cys-rich domain Both the RBD and Cys-rich domain are essential in targeting...
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Báo cáo khoa học: Crosstalk between Src and major vault protein in epidermal growth factor-dependent cell signalling docx
... what is the clinical significance of the interaction between Src and MVP in those cancer cells, which are overexpressing these proteins Furthermore, Src may not be the only tyrosine kinase that ... nitrocellulose, then immunoblotted with anti-Flag mAb and anti-Src mAb The PAP treatment markedly reduced the interaction between MVP and Src, suggesting that the interaction is dependent on protein tyrosine ... tyrosine kinase activity Domains within Src kinases target the enzyme to specific subcellular locations where they bind to regulatory and ⁄ or substrate proteins and are integrated into cell signalling...
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Báo cáo khoa học: Direct interaction between CD91 and C1q docx
... more of these ligand-binding clusters Some inhibition was also observed with the CD91 ligands a-2-macroglobulin and exotoxin A These ligands occupy the CD91 ligand-binding cluster II and IV, thereby ... partners of CD91 and C1q inhibit their interaction To characterize the CD91–C1q interaction in more detail, the ability of known ligands of either protein to interfere with binding was investigated ... an inhibitor of the C1q–CD91 interaction The calreticulin inhibition indicates that only a part of the binding sites on C1q is shared between CD91 and calreticulin No binding was detected between...
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Báo cáo khoa học: NrpRII mediates contacts between NrpRI and general transcription factors in the archaeon ¨ Methanosarcina mazei Go1 pot
... Binding of NrpRI to the operator sequence was further verified by EMSA, as described in the Materials and methods, using a radiolabeled PCR product of the glnK1 promoter, including the BRE- and ... further verifying formation of a complex between NrpRI and NrpRII The presence of 10 mm 2-oxoglutarate significantly decreased the binding of MBP–NrpRI to the operator as well as the binding of the ... domains participate and are required for the full 2-oxoglutarate response Evidence was obtained that the conserved amino acids C148 and L195 located in the first, and C389 and H435 located in the...
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Báo cáo khoa học: Adenine and adenosine salvage pathways in erythrocytes and the role of S-adenosylhomocysteine hydrolase A theoretical study using elementary flux modes Stefan Schuster and Dimitar Kenanov ppt
... of them involve the modes starting from adenine obtained in the first simulation and include methyltransferase and SAHH2 in addition Some others involve the modes starting from adenosine obtained ... is involved in these pathways Since adenine is a substrate of ADPRT, the elevation of ATP in the absence of adenosine kinase shows that adenine must be released in the process before being incorporated ... 10 pathways starting from adenosine (rather than S-adenosylmethionine) and involving SAHH1 in the backward direction and SAHH2 in the forward direction This is a novel result because these pathways...
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báo cáo hóa học:" Do diabetes and depressed mood affect associations between obesity and quality of life in postmenopause? Results of the KORA-F3 Augsburg population study" pdf
... participated in the preparation and conduct of the study and the editing of the article MEL participated in the conduct of the study and the editing of the article KHL participated in the preparation and ... of the study and the editing of the article TvL participated in the preparation and conduct of the study, the statistical analyses and the writing of the article All authors read and approved the ... women most in need may be those obese and feeling depressed Regarding mental HRQL, obesity and diabetes as interacting factors seem worth of further scrutiny In future studies, the underlying pathophysiological...
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Báo cáo toán học: " Music-aided affective interaction between human and service robot" pptx
... users and corresponding information in order to utilize them during the interaction with humans Finally, the expression system executes the behavior accordingly and expresses emotions of the robot ... naturally and emotionally interact with humans For the music-aided affective interaction, the mood of the music is recognized in the perception system and is utilized in the determination of the user’s ... data In addition, we will investigate an ideal combination of emotional features and classifiers including SVM and HMM in the proposed approach Competing interests The authors declare that they...
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Báo cáo hóa học: " Evaluating interaction forces between BSA and rabbit anti-BSA in sulphathiazole sodium, tylosin and levofloxacin solution by AFM" potx
... anti-BSA in the solution These findings may enhance our understanding of antigen/antibody binding processes in the presence of drug molecules, and hence indicate the AFM could be helpful in the design ... polymyxin B affected the molecular interaction between lipopolysaccharide (LPS) binding protein-LPS complex and the receptor protein using AFM and different structures of the drugs resulted in different ... protein-protein interactions In addition, increasing the solution IS may disrupt the hydration shell coating on protein surfaces and thus reduce repulsive interactions between the two interacting surfaces [38]...
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Báo cáo y học: "The relationship between inflammation and new bone formation in patients with ankylosing spondylitis" docx
... in and between individuals It was no surprise, therefore, that when we did the analyses on an individual patient basis, no differences in the proportions of patients with and without spinal inflammation ... showed inflammatory lesions at BL as compared with those edges that had not been inflamed in either the BL or the 2yFU Nevertheless, our findings are in line with previous data of ours [26,28] and ... imaging of the spine and the sacroiliac joints in ankylosing spondylitis before and during therapy with etanercept Ann Rheum Dis 2005, 64:1305-1310 15 Sieper J, Baraliakos X, Listing J, Brandt J,...
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Báo cáo y học: " The contrasting roles of PPARδ and PPARg in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue" ppt
... changes The Δ 6-desaturase is integral to both pathways; the enzyme introduces the initial double bond into linoleate forming g-linolenate in the ω-6 pathway and introduces the double bond into linolenate ... differing relative doses and regimes, and so the effectiveness of short term lipid lowering in blood plasma may be variable The detected increase in certain TAGs containing C16 and C18 saturated and ... using the murine 3T3-L1 adipocyte cell line The ob/ob mouse was used to investigate the influence of PPAR activation on adipose tissue metabolism in a model of insulin resistance and obesity The...
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Báo cáo y học: "Adrenal suppression due to an interaction between ritonavir and injected triamcinolone: a case report" docx
... evaluate the interaction of injected steroids and ritonavir We advocate that any use of steroid supplementation, including intra-articular injection, should be used with caution in the setting of ... review by the Editor -in- Chief of this journal Competing interests The authors declare that they have no competing interests Authors' contributions All authors participated in the drafting of the manuscript ... is exploited to increase the bioavailbility of other PIs and increase their dosing intervals [7,8] However, ritonavir increases the concentration of exogenous steroids through the same mechanism...
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Báo cáo y học: "Role of innate signalling pathways in the immunogenicity of alphaviral replicon-based vaccines" potx
... is indeed more immunogenic than deltaREP (convDNA vaccines) [32,33] Replicon induced CD8+ T cell responses in the absence of TLR signalling Earlier studies investigating innate signalling pathways ... important signalling molecule for the induction of type I IFNs and proinflammatory cytokines, is needed for a fullminant immune response Interestingly, the immune responses are suppressed in both ... has not yet been investigated in head-to-head comparisons if these are the same for DREP vaccines In this study we investigated if innate signalling pathways are important for the immunogenicity...
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