... superimpo-
sition of five-residue segments ofthe crystal structure on the equivalent segments of each member ofthe family ofthe solution structure
ofthe M domain of human eRF1. The resulting rmsd ... S4. A comparison of part ofthe protein backbone
structure ofthe representative solution structureof
the human eRF1 M domain andthe Ca trace in the
crystal structureof RF1 in the whole ribosome ... simi-
larity to the crystal structureofthe M domain of the
same protein [3], but it is far from identical (Fig. 2A).
The rmsd ofthe superposition ofthe heavy backbone
atoms (Ca, N, O and C) ofthe family...
... us. Neither of these
parameters are within the range of our experimental
observations, and therefore the predominant species in
solution are the monomer and dimer. Additional evidence
that the crystallographic ... arrestin and arrestin in the presence of
phosphopeptide is given at the top ofthe (B) and (C), expressed as a
percentage ofthe total signal from the detector.
Ó FEBS 2002 Activation of visual ... over the use ofthe distance distribution
function, which requires a prior estimation ofthe maximal
dimension.
The forward scattering is proportional to the product of
the molecular mass and...
... examine the
validity ofthe measures devised to ascertain and quantify social anxiety,
as this is most relevant to social phobia.
Examination ofthe validity both ofthe construct andofthe methods
assessing ... comparison to the normal, thesocial phobic
response is exaggerated, over-generalized, and chronic. The issues raised
by these incompatible points of view attending the inception of the
notion ofsocial ... heightened sense of propriety
and blushing were expressions of shame. Social anxiety is evoked socially
The Genealogy ofSocial Phobia 19
To my wife
and to
the memory of my mother À who taught...
... between the
Leu residues from v-KIND and MAP2 contributes to
the interaction between the two proteins.
In conclusion, the present study has clarified the
structural and functional importance ofthe ... and 482) and
one Thr residue (amino acid 487) were well conserved
in the KIND2 of v-KIND in all species analyzed,
although not in the other KINDs. To investigate the
possible involvement of these ... under-
stood, the data obtained in the present study indicate
that the 43 residues (amino acids 702–744 in mice) that
reside in the middle region ofthe CD act as the
v-KIND binding core. The v-KIND-binding...
... W,is
simply the sum ofthe body mass of all individuals. For organisms ofsimilar size, it
can be estimated by taking the product ofthe population, N,andthebodymass,
M. Similarly, the store of each ... obvious.
We asked the author(s) of each paper to examine the importance and role of
body size in the systems in which they work. Essentially the book builds from the
level ofthe individual and a consideration ... level to the
flux, storage and turnover of these elements at the level of ecosystems.
Our second example concerns the role of metabolism in trophic relationships,
including thestructureand dynamics...
... splitting
constants of the
15
N nucleus ofthe distal NO andof
the
14
N nucleus ofthe proximal His ofthe GmHO-1
complex are closer to those ofthe rHO-1 complex than
to those ofthe SynHO-1 complex. Thus, ... analyses of the
molecular features ofthe heme–GmHO-1 complex and
ofthe mechanism of heme degradation were per-
formed, andthe results were compared with those for
the heme complexes of SynHO-1 and ... (B) and 25 K for (C)–(E).
(A) The ferric heme complex of GmHO-1 at pH 7.0 (0.1
M, KPB).
a-1, Expansion ofthe g
xy
region of (A) (solid line) andofthe corres-
ponding part ofthe spectrum of...
... basis for structure- activity studies. The high
selectivity ofthe a-conotoxins, together with the possibility
of obtaining detailed information on their three dimen-
sional structures andthe relative ... native and
heterologously expressed nAChRs
The examples presented above clearly demonstrate the
usefulness of a-conotoxins in the determination of the
structureand function of native nAChRs, and ... so far. The great variability of the
conotoxins and their highly specific action on different ion
channel subtypes derives from thestructureofthe peptides
which have evolved conserved and hypervariable...
... resemble teardrops [32].
Further examination ofthestructureand sequence of
sbwAFP and TmAFP reveal other similarities (Fig. 8 C).
The panel shows the similarity ofthe TXT face again, a nd
also ... determine the handedness ofthe proteins, or
may prevent the unfolding ofthe protein at cold temper-
atures.
The b-helix as an AFP structural motif?
The sbwAFP and TmAFP structures represent the first
AFPs ... of
X-ray structure with 5 °C NMR structure using the main chain of
residues Ser12 fiThr70 in t he structure a lignment. (B) O verlap of the
X-ray structure with the 30 °C NMR structure using the main...
... SDS/PAGE and in 2D PAGE (Figs 1 and
2; Table 1).
The N-terminal amino acid sequences (see above) allow
the assignment ofthe HcA clone to the major sequence of
the upper hemocyanin band in the SDS/PAGE ... against the hemocyanin fraction show
staining ofthe two 75 kDa bands in Western blot, but do
not recognize any other proteins ofthe hemolymph.
Although we expected that each of these bands contains
two ... primers andthe T3 vector primer. The
sequences were obtained after the cloning ofthe PCR
products into the pCR4-TOPO TA vector (Invitrogen).
Protein structure modeling
Homology models ofthe S....
... orm
of b strand [18].
The positive bands at » 1675 cm
)1
in the amide I r egion of
the ROA spectra of b-andj-casein, which originate mainly
in the peptide C O stretch, are characteristic of ... (although there is a hint) in the ROA spectra
of b-andj-casein may be evidence that, as suggested
previously [3], the b -structure identiđed above mainly t akes
the f orm of unassociated b strands rather ... positive ROA
at » 1320 cm
)1
to PPII structure relies mainly on the
evidence outlined above.
In view ofthe c lose similarity ofthe ROA spectra of the
casein, synuclein and tau proteins shown in t his...
... model ofthe
role of point of view in problem solving.
SUMMARY
We have reported here a three
pronged approach to
the study of problem solving action and report: I) the
collected of data ... solving and talk about
problem solving, 2) development of a process model of
these behaviors, and 3) use of coding techniques to
extract traces of "critical phenomena" from the
transcripts ... relltld ~O
the
~r~romnoe oF
5he
problem tooK, lad o~here tt~c
are oZoeely related to the report ofthe task aoClona.
~n the psr~lo,,~ar problem demean ofthe H~aeionsr£ee
and CannLbae8 pusxle,...