... irth ofthe F emale B rain glanced at their mothers’ faces. They frequently touched the forbid-den toy cow, even though their mothers shouted, “No!” The one-year-old boys, driven by their ... to get to the clothes hanging in their closets. One girl had a pink two-piece outfit, and the other had a green two-piece outfit. Their mother giggled every time she’d see them switch the tops—pink ... adjoined each other. The sandbox was in our yard, and the swing set straddled the invisible line that divided our properties. Our mothers, who soon became friends, saw the advantage of their two...
... allowthem to gauge the extent ofthe starry congregations withoutleaving the surface ofthe Earth. The most important clue to the distribution of stars is the phenomenon we call the Milky Way. The ... ofthe sky is, of course, due to the rotation ofthe Earth, not the sky, and we know that the starsare not all at the same distance, as they would be if they werefixed to the inner surface of ... sense the slow rotation of the sphere, carrying the stars across your field of view from east towest, and slinging them underneath you on the other side of the Earth. The apparent daily movement of...
... admission to the servants of such persons as were attending the theatre." On the second night ofthe performance of the farce, Mr. Love, one ofthe managers ofthe theatre, came upon the stage, ... this time the servants were admitted gratis to the upper gallery ofthe theatre on the conclusion ofthe fourthact ofthe play ofthe evening. In 1697, however, Rich, the manager ofthe theatre ... devote himself to the study ofthe law, and subsequently to the production of novels. Andwith the passing ofthe Licensing Act terminated the existence ofthe Master ofthe Revels; the Act, indeed,made...
... was the readiest way of converting them to the principles ofthe Christian religion. These, then, were the first forerunners in the great cause ofthe abolition ofthe Slave Trade: nor have their ... held the reigns ofthe government of Spain till Charles the Fifth came to the throne, for the establishment of a regular system of commerce in the persons ofthe native Africans. The object of ... consigning to it those of another. Ximenes, therefore, may be considered as one ofthe first great friends ofthe Africans after the partial beginning ofthe trade. This answer ofthe cardinal, as...
... from the rest ofthe mapping tori as a purelyTQFT consequence of Corollary 1.In this paper we have initiated the program of using ofthe theory of Toeplitz operators on the moduli spaces in the ... multiple ofthe identity. Wewill suppress the superscript on the quantum representations and simply writeρk= ρn,dkthroughout the rest ofthe paper.Our key idea in the proof of Theorem 1 is the ... (see the proof of Theorem 7). Theorem 1 now follows directlyfrom knowing which elements ofthe mapping class group act trivially on the moduli space M. The assumptions on the pair (n, d) in Theorem...
... ofthe first 88amino acids of PPI1 may participate in the interactionwith the H+-ATPase and makes PPI1588His6a suitabletool to study the mechanism of action of PPI1. The analysis ofthe ... 14-3-3s.Results The C-terminus of isoform 1 ofthe PM H+-ATPase of A. thaliana (AHA1) interacts with the first 88 aminoacids of PPI1 [22], indicating that the PM H+-ATPasebinding site of PPI1 is ... role in the subtle modulation of proton extru-sion in response to endogenous or exogenous signals. The two-hybrid screen for interactors ofthe C-termi-nus of AHA1 led to the isolation of a cDNA...
... imagine the old knight, onlyhalf aware ofthe sunshine ofthe evening, the noise ofthe streets, the looks ofthe crowd, the great minsterrising half-finished in the midst ofthe town by the Rhine, ... feudalism, rendered such a story unintelligible to the Germans ofthe Othos and Henrys. In the Nibelungenlied, the whole storyofthe massacre ofthe brothers is changed. Chriemhilt never forgives the murder ... orders ofthe father ofthe family, and to the economy ofthe house-under the superintendence ofthe mother; a manner of living at once business-like and patriarchal, expoundedpounded by the interlocutors...
... on Earth. The proof as they say, is in the pudding! Be patient in the beginning – all the information in the early chapters will come together in theend It took me 14 years of work and ... their workouts or they see themselves successfully completing a lift or performing aerobic training. They also see pictures of their bodies the way they want them to look when they reach their ... sabotage their efforts to lose body fat. The conscious mind is a lot like the captain at the bridge of a ship. The captain gives a command and sends it down to the engine room. The subconscious...
... (i.e. the spectral density function at the Larmor frequency of the 15N) and J(0.87xH) (i.e. the spectral density function at the 0.87 times the Lar-mor frequency of the 1H) are independent of ... responsible, from a thermodynamic point of view, for the binding ofthe monomeric species of CAC?We have previously discussed the variation in the freeenergy of binding as a function ofthe changes ... rotational movement of the molecule). Furthermore, the internal motions of each bond vector are independent of each other, but the rotational diffusion ofthe molecule affects each of thosebond vectors...
... system of His15 and a distortion of the N-terminus ofthe first helix, which supports the histidinering. In ad dition, the C -terminal helix is bent because the sidechain of Leu86 located at theend ... wascomputed as the ratio ofthe s tandard deviations of the chemical shifts ofthe amide nitrogen and p roton nuclei.ResultsDetermination ofthe three-dimensional structure of HPr(I14A)To allow the comparison ... protein and other HPr molecules. The analysis ofthe 10 lowest energy structures with the Fig. 1. Dependen ce of 1HN-15N residual dipolar couplings on secondarystructure. Thesizeofthe1HN-15N...
... opportunity of alleviating the extremehunger that I suffered with the refuse ofthe table of one of my acquaintances.At theendofthe month (December 1770), they reached the woods, a thick growth of ... with one another the weapons of their common stock. The advance was made in the middle ofthe night, but at this season of the year the whole {60} scene was brilliant with the light ofthe midnight ... land offered nothing to their search, the air was moderate and the weather singularly mild. The broad sheet of open water, ofthe very colour ofthe ocean itself, buoyed up their hopes of the...
... charac-terize the impact of BACE1 inhibition as a putativetherapy for the treatment of AD. We found that the de novo production and the endogenous levels of ICDswere not reduced by deletion of BACE1. ... is the b-site APP-cleaving enzyme 1 (BACE1). Here, we investigated the effects of genetic manipulation of BACE1 on the processing ofthe APP family of proteins. BACE1 expression regulated the ... inhibition of BACE1 will not adversely affect the potentially important signaling role ofthe ICDsreleased by the APP family of proteins, but mayimpact on other functions of this family of proteins.Experimental...
... description of the molecular components involved in the regulation andmaintenance of dendritic spine morphology is funda-mental to our understanding ofthe functions of the central nervous system. The ... (Fig. 2A,B). The NMRspectra of these constructs perfectly resembled the spectra of unfolded proteins: they showed no signs of either amide proton dispersion, which is indicative of hydrogen bonding ... [38]. In the presence of theseABD constructs, the concentrations of fluorescentactin polymers appeared to be higher because of the precipitation of crosslinked actin polymer networksonto the glass...