... neither on the morphology nor on thedynamicsoftheepithelial disease Inthe interpretation ofthe disturbances oftheepithelial architecture, this book partly relates to the morphology ofherpes ... Chapter The Morphology of Varicella- ZosterVirusEpithelialKeratitisinHerpesZosterOphthalmicus Before the introduction of newer methods, the gold standard of detection and identification of viruses ... and cell debris; in places, the red staining is confluent Chapter 1 The Morphology of Varicella- ZosterVirusEpithelialKeratitisinHerpesZosterOphthalmicus VZV Epithelial Keratitis: Surface...
... subdomain 1, where the spin probe is attached, is not directly involved inthe intermonomer cross-link, because one ofthe cross-linking sites is occupied by the spin probe, therefore, the rigidity ... complexes the motion ofthe probe is less restricted relative to the strong binding state and there is no difference between the two weak binding complexes Inthe case of cross-linked F-actin, the ... study, the interaction of ATP and S1 with actin during activation of myosin S1 ATPase using caged ATP did not produce an increase in rotational motion inthe environment ofthe Cys374 site of actin...
... first infectious clone of AAV serotype (AAV2) in 1982 [7] and the pioneering work on the successful cloning of AAV establishing the foundation of recombinant AAV vectors capable of expressing foreign ... to the forefront of gene therapy inthe past decade The exponential progress of AAV-based vectors has been made possible by the advances inthe knowledge ofthe virology and biology of this virus, ... 1980s, pioneering work on the successful cloning of AAV established the foundation of recombinant AAV vectors capable of expressing foreign genes in mammalian cells Since then, the AAV has been...
... first infectious clone of AAV serotype (AAV2) in 1982 [7] and the pioneering work on the successful cloning of AAV establishing the foundation of recombinant AAV vectors capable of expressing foreign ... to the forefront of gene therapy inthe past decade The exponential progress of AAV-based vectors has been made possible by the advances inthe knowledge ofthe virology and biology of this virus, ... 1980s, pioneering work on the successful cloning of AAV established the foundation of recombinant AAV vectors capable of expressing foreign genes in mammalian cells Since then, the AAV has been...
... elucidate the molecular basis ofthe attenuation ofthe VZV vaccine strains Keywords Varicella- zoster virus, SuduVax, Genome, Phylogeny Background Varicellazostervirus (VZV) is an alpha-herpesvirus ... Vaccine strains are separated from clinical strains, but formation of clade is not evident In order to find which ORFs are important in distinguishing vaccine strains from clinical strains, further ... deletions resulted in deletion of amino acid S residue On the other hand, insertion of three nucleotides ATG at position 27 was found in ORF60 ofthe strain SuduVax Interestingly, the aforementioned...
... responses to varicella and herpeszoster infections J Clin Microbiol 1980, 12:367-374 Cohen PR: Tests for detecting herpes simplex virus and varicella- zostervirus infections Dermatol Clin 1994, ... be explained by the early initiation of antiviral therapy at the day of rash onset We conclude that the analysis of VZV-specific CD4+ T-cells might support the rapid diagnosis of primary varicella ... certain circumstances, as for example in cases of atypical or subclinical varicella or inthe absence of detectable VZV DNA in plasma Consent Written informed consent was obtained from the patient...
... represents the inertial filling inof dips and knocking out of bumps on the ‘bare’ surface caused by rolling grains flowing over the top The λρ(|h x | − tan α) term represents the tendency of flowing grains ... evolves under thein uence of two distinct types of mechanism Firstly, the impact of a constant flux of saltating grains knocks grains out ofthe ‘bare’ surface, causing them to hop along the ripple ... revealed the same trend 11.4.2 Homing in on the physics: a discussion of smoothing in Case B We focus in this section on the physics ofthe equations and the results Inthe regime of continuous...
... choose the following method of mitigating the problem of changing sample composition: Instead ofthe exposure levels Xi (t), we investigate the change inthe exposure ofthe same bank, as stated in ... investigate the determinants ofthe banks’ exposure to interest rate risk They find that the belonging to certain banking groups, the banks’ size, their earnings and balance composition, and the ... positions in their banking book Our dataset concerning the Basel interest rate coefficient consists of two sources: the notifications inthe event that the losses exceed 20% ofthe own funds, and the information...
... might influence the pricing behavior ofthe merged bank, and we include these in our model The first is the change in market share When two banks operating inthe same market merge, their joint ... we with the ratio ofthe number of markets in which a bank operates inthe years before and after the merger Again, we include the cross-product ofthe CNM variable and the time after the merger ... significantly increase during the third year Inthe following years, the effect is negative We interpret this dynamic path of MMDA rate changes as a result ofthe post-merger integration ofthe pricing...
... avoid treating their networks of relationships as if they were a web of zero-sum games—repeatedly trading off the interests of one stakeholder in favor ofthe interests of another We further recommend ... further actions This is not the first foray into the topic of trust by either organization Since its founding in 2004, the Institute has made trust the overarching theme of its work, which includes ... Professor of Business Administration Darden School of Business, University of Virginia Jared Harris Assistant Professor of Business Administration Darden School of Business, University of Virginia...
... portion ofthe protein, directly involved in binding, experiences an average order parameter increase of 0.04 [52] In these studies, the increased mobility in large sections ofthe protein was interpreted ... changes inthe dynamic properties ofthe protein rather than by changing the structure ofthe protein itself In fact, protein function depends vitally on its structure and dynamics; if a stabilizing ... in which thedynamicsof a protein are investigated in different conditions invariably find increases in correlation times upon ligand binding which are interpreted inthe light ofthe higher mass...
... history of pulmonary TB; by administering a questionnaire to every participant Furthermore other clinical diagnostic information of co-morbidity including TB, clinical stage of HIV; treatment ofthe ... divided into the initial phase (intensive) and continuation phase Inthe intensive phase the majority of TB bacilli are rapidly killed and infectious patients become non-infectious within one ... reduction ofthe severity of HIV infection and in one way or another will consequently reduce the susceptibility of opportunistic infections among HIV patients The therapy involves a combination of protease...
... be shopping online or reading email We report on these and other findings inthe following sections We first survey the related work in section We then describe the characteristics ofthe incentivised ... behavior in section Next we concentrate on the various aspects ofthe recommendation success from the viewpoint ofthe sender and the recipient ofthe recommendation in section The timing and the ... models of adoption we discuss TheDynamicsof Viral Marketing next Most ofthe previous research on the flow of information and in uence through the networks has been done inthe context of epidemiology...
... cope with devastation inthe inner city, the size ofthe problem dwarfs the size ofthe response Initiatives like these often prompt observers to wonder if the purpose ofthe program is to provide ... history of unjust treatment of persons of color Then, beginning inthe mid-1970s, in a more conservative political climate, the government began to take back these hard-won gains 30 TheDynamicsof ... 39 origins inthe late nineteenth century, the twin pressures of containment and change have made social work, like the welfare state, an arena of struggle Reflecting the mandates ofthe profession...
... JNHT]), the introduction of archaeology at the University ofthe West Indies in 1987, and improvements inthe training of Jamaican archaeologists The past decade has seen increased interest in Jamaican ... decade The second article, “Taíno Settlement ofthe Kingston Area”, reports on a survey of eighteen sites in Kingston The authors examine the findings of two pilot studies, an examination ofthe ... by the Heye Foundation, Museum ofthe American Indian She also promoted her interests among the staff ofthe Institute of Jamaica, resulting in an exhibition of pre-Columbian artefacts at the Institute...
... by using this method One is the level of fishing effort (FMSY ), which is associated with overfishing, or the process of taking out more than the MSY level of harvest The other is the size ofthe ... of change and interactions that occur at different levels of analysis, including the economics ofthe fishing industry, the politics of domestic agenda setting, and the relations of international ... changes inthe status quo However, it cannot provide unambiguous evidence regarding the role of a regime in maintaining species or stocks of individual species in a healthy condition The range of...
... 4% inthe area of Substance Use to 16% inthe area of Specialty and Inpatient Hospital Care (see Table 3) Overview of analysis oftheDynamicsof Care We conducted a series of analyses on theDynamics ... from the baseline and three-month interviews The informed consent process occurred at the time ofthe baseline interview Each interview took 30–45 minutes to complete and was conducted either in ... those findings inthe description of each analysis http://www.hqlo.com/content/6/1/20 Stage of help-seeking and factors that influenced helpseeking decisions The first section oftheDynamics of...
... events, leading, however, to the deletion ofthe hairpin-forming sequences (A Plyusnin, unpublished observations) The role of RNA folding in hantavirus recombination awaits further investigation ... Figure recombinant S RNA segments Checking of specificity of RT-PCRs for the wt and the Checking of specificity of RT-PCRs for the wt and the recombinant S RNA segments Lines 1–3: products of RT-PCR ... for the recombination "hot-spot" inthe plus- and minus- sense S RNA of TULV Hairpin-like Hairpin-like structures predicted for the recombination "hot-spot" inthe plus- and minus- sense S RNA of...
... signaling is important inthe induction of innate cytokine responses to TMEV infection In this study, we investigated the role of TLR3-mediated signaling inthe development of TMEV-induced demyelinating ... signaling plays an important role in controlling viral load inthe CNS and in preventing the development of TMEV-induced demyelinating disease following infection with a less virulent BeAn strain in ... cellular infiltration into the CNS by activating higher levels of inflammatory cytokines and chemokines To further determine the levels of virus- specific CD4+ and CD8+ T cells that infiltrated into the...
... events, leading, however, to the deletion ofthe hairpin-forming sequences (A Plyusnin, unpublished observations) The role of RNA folding in hantavirus recombination awaits further investigation ... Figure recombinant S RNA segments Checking of specificity of RT-PCRs for the wt and the Checking of specificity of RT-PCRs for the wt and the recombinant S RNA segments Lines 1–3: products of RT-PCR ... for the recombination "hot-spot" inthe plus- and minus- sense S RNA of TULV Hairpin-like Hairpin-like structures predicted for the recombination "hot-spot" inthe plus- and minus- sense S RNA of...