... HAD using standard-of-care approaches for Thailand In general, the evaluation included participant and proxy informant reports of symptoms and function, the HIV macroneurological examination as ... validated in Thailand [18] The assessment was a clinical assessment made by the protocol neurologist (P S.) at the time of clinical evaluation using the TDI, patient interview, and patient and proxy information ... traffic tothe CNS The work was completed using a cohort in Bangkok, Thailand, which was established to characterize cognition among individuals initiating HAART for the first time as the country rapidly...
... TCC AC 184I: GAT CCT ACA TAC AAA TCA TCT Pr-2W: CT GAA ATC TAC TAA TTT TCT CCA CT Pr-2M: CT GAA ATC TAC TAA TTT TCT CCA CC Pr-B: GGA TGG AAA GGA TCA CCA GCA Page of (page number not for citation ... sequencing, the line probe assay, and the recombinant virus assay [33] The line-probe assay and ARMS-PCR detected minor variants that in particular cases made up only 1% of the viral population ... their mean CD8+ cell count was 999.1 ± 598.4 cells/mcL POL Pr-2: TCA TTG ACA GTC CAG CTA TCC TTT T 184U: TAC AAT GTG CTT CCA CAG GG 184W: TCC TAC ATA CAA ATC ATC CAT 184G: CCT ACA TAC AAA TCA...
... Jersey) inthe same laboratory in Dakar End Points and Statistical Analysis The primary end point was the percentage of patients with plasma HIV-1 RNA < 500 copies/mL at month Secondary end points ... a day according to body weight The EFV dose was increased to 800 mg in all patients who were concomitantly receiving rifampicin Two Dakar hospitals participated inthe study (Service des Maladies ... by the trial physician and the pharmacist at each visit Interviews with thepatient were done in French or inthe local language (Wolof) using standardized questions focusing on adherence to the...
... rest, they say, was history Fascinatingly, at the 10-year anniversary of the initial patient, thepatient underwent elective repeat angiography which noted that the LAD narrowing remained almost ... which affected the basal ganglia the day after CAS The fatal ICH reported by Abou et al (2004) appeared at the level of the basal ganglia one hour after CAS Finally, the series of 161 patients ... can play a role inthe pathogenesis of post-CEA hyperperfusion, leading to widespread endothelial damage inthe ipsilateral cerebral arteries and thereby increasing the risk of ICH inthe early...
... during the treatment of AIA rats At 13 days after arthritis induction, the ankle size of most of the AIA rats reached a plateau (data not shown) At this time, the hind legs of the affected animals ... (AIA+Dex) had approximately 48% less osteoclast surface than the AIA+saline group, whereas the AIA+P-Dex group had approximately 82% less osteoclast surface The osteoclast surface inthe AIA+P-Dex ... confirms the acidosis condition inthe arthritic joints of AIA rats In addition to making general observations of the animals, we measured the change in ankle size with a digital caliper during the...
... Four patients with CHF had received all treatment in hospital rather than primary care inthe previous 12 months These patients were excluded for further analysis, leaving a total number of 25 patients ... examined in chronic illness care Thus, our aim was to measure information exchange networks related to individual patients with a chronic disease, including relevant health professionals and the patient, ... objective was to examine the variation of network characteristics across individual patients, because this would open the possibility that these characteristics are related to relevant outcomes and across...
... Sakamoto N, Nakagawa M, Korenaga M, Hino K, Hige S, Ito Y, Mita E, Tanaka E, Mochida S, Murawaki Y, Honda M, Sakai A, Hiasa Y, Nishiguchi S, Koike A, Sakaida I, Imamura M, Ito K, Yano K, Masaki ... IL28B Variant calling and association testing CRISP detected 1221 SNVs and 118 indels (1339 variants in total) Validation with original GWAS SNP data and HapMap data CRISP called all 15 of the SNPs ... read pairs aligning tothe same location to be biological rather than PCR duplicates Hence, duplicate removal was not performed Variant calling and association testing using pooled DNA Variant...
... meta-analysis have implications for clinical practice The results from the meta-analysis show that in general atomoxetine and methylphenidate have comparable efficacy and equal acceptability in ... designing the study, data collection and analyzing the data RH and VdeS drafted the manuscript All authors read and approved the final manuscript Competing interests RH and VdeS have received travel ... Psychiatric Association, Washington, DC; 2000 Detsky AS, Naylor CD, O’Rourke K, McGeer AJ, L’Abbe KA: Incorporating variations inthe quality of individual randomized trials into metaanalysis J Clin Epidemiol...
... areas All Norwegian acute psychiatric services are public and available to everyone All the patients inthe catchment areas are admitted tothe local study centre Acute admissions to other psychiatric ... Ordinal variables will be analysed using non-parametric tests in addition to using T tests and ANOVA Time to remission and/or response will be analysed using survival analysis The statistical analysis ... weeks, the ECT treatment is terminated and thepatient is switched to maintenance therapy If apatient or the treating clinician decides that thepatient could receive better treatment outside of the...
... through ascending tracts tothe thalamus and higher brain centers Pain information however, can be modulated by the activity of descending inhibitory fibers passing from the brain tothe spinal cord ... the visual analogue scale (VAS) was about 70–75 mm, with being none and 100 being maximum pain The initial Nirschl stage was [10] She was prescribed duloxetine ina dose that was increased to 60 ... cord The neurotransmitters primarily involved inthe descending pathways, that is, norepinephrine and serotonin, act synergistically in reducing the transmission of pain information from the periphery...
... Isaacs & Lindenmann in 1957 Interferon-alpha has been used for the treatment of chronic viral hepatitis for more than 20 years [5] Many large clinical trials [6-8] and a meta-analysis [9] have ... (Equipar, Saronno, Italy) drew from the study because of side effects However, case inthe CIFN group and cases inthe IFN-alpha group had missing data at the end of treatment All patients inthe ... response was defined as HBeAg seroconversion, clearance of HBV DNA and normalization of ALT Partial response was defined as normalization of ALT and no HBV DNA clearance but a reduction in hepatitis...
... have placebo mortality rates ranging from 31% to 61%, whereas an apparent lack of efficacy in other trials occurs across a spectrum of baseline mortality risk There are several important flaws ... truly lacking in clinical efficacy; that the absence of activity reflects benefit in some patients, and harm in others; or that the agent is efficacious, but the magnitude of that activity is too ... treatment-severity interaction Moreover, the analysis confuses severity as a population descriptor with severity as a descriptor of individual patients within that population Assuming that the potential to respond...
... Hollins [2] suggest that RCTs that not have a placebo group may be inappropriately penalised, as a placebo in manual therapy that has no effect and is believable by thepatient is not available at ... Chiropractic Examiners: Job Analysis of Chiropractic in Australia and New Zealand: A Project Report, Survey Analysis, and Summary of the Practice of Chiropractic within Australia and New Zealand Greeley, ... significant difference between the groups There was a mean difference of 0.037 in favour of the Activator in left lateral flexion and a mean difference of 1.928 in favour of the Activator in right lateral...
... Institute, Cary NC) was used for all analyses Results 3.1 Patient disposition Data from a total of 794 patients were included inthe analysis The age range was to 15 years The mean age was 9.7 years ... Cochran-MantelHaenszel test controlling for study inthe case of categorical variables Treatment efficacy over time was analyzed on an intent -to- treat basis The intent -to- treat population included patients ... for the total score, the Emotional Comfort sub-domain, and for the Achievement domain with its two sub-domains Academic Performance and Peer Relations Inthe Risk Avoidance domain, there was a...
... stroke patient Intracranial hematoma: The formation and the size of the hematoma will define the severity of increasing ICP The clinical manifestation includes: subarachnoid hemorrhage, intracranial ... saline was more effective than mannitol Suares at al (1998) Hypertonic saline played a role in treatment of brain edema, promising agent for brain injury and post-operative patient Francony at ... elevated intracranial pressure Reduce of cease of blood flow tothe brain When intracranial pressure reach the mean arterial blood pressure, the flow tothe brain will stop, it similar to cardiac arrest...
... (FLT3), varying from to 400 base pairs inthe juxtamembrane d omain, are found in 20-25% of adult AML cases.1-3 In addition, activating point mutations inthe second kinase domain occur in about ... resistance to apoptosis The mainstream chemotherapy regime for AML is a combination of cytosine arabinoside (Ara-C) and anthracyclines such as doxorubicin (Dox) Despite initial responses to chemotherapy, ... average size, Ara-C was intraperitoneally (I.P.) injected at 10 mg/kg/day for consecutive days ABT-869 was administrated at 15 mg/kg/day by oral gavage daily Inthe combination group Ara-C was...
... stroke incidence There are insufficient data in medical ICU patients, but in CTS patients it is clear that the stroke incidence is increased in patients with AF Besides AF, a proinflammatory state ... [91,94-97] A meta-analysis showed that class IA, class IC and class III antiarrhythmic agents are equally effective in obtaining SR [98] Meta-analyses comparing amiodarone with class IC antiarrythmic ... knowledge about AF is gained from studies in noncritically ill patients AF is probably the final common pathway of structural changes in combination with a trigger leading to abnormal activation patterns...
... Carbamazepine acts as an inducer of cytochrome 3A4 , which may increase the metabolism of some anticoagulant and cardiovascular medications Olanzapine may induce or worsen cardiac risk factors ... exploration of the antiemetic activity of olanzapine for the relief of nausea in patients with advanced cancer and pain J Pain Symptom Manage 2002, 23:526-532 Khojainova N, Santiago-Palma J, Kornick ... review paper, participated in drafting the manuscript, and presented the findings, in part, at the American Psychiatric Association annual meeting in San Francisco, CA on May 18, 2003 Both authors...
... regarded as an alternative therapeutic approach to HBO as an adjuvant to antibiotherapy inthe control of sepsis regarding their effects via modulation of the oxidative/antioxidant status ACKNOWLEDGMENTS ... score was calculated by adding the individual scores for each category and the scores for each histological parameter were summed up toa maximum score of 16 Statistical analysis Normality analyses ... blood of a septic patient who was hospitalized at Gulhane Military Medical Academy Hospital (Ankara, Turkey) Sepsis induction was started at the same hour (8 a. m.) in all groups to prevent the possible...