... the vasethis time the line will detour around the bottom edge ofthe vase, and it will progressfollowing the outline ofthe vase until itreaches the other side ofthe paper. This part of the ... construction. The firstbeing the top half ofthe silhouette, the second being the bottom part of the silhouette, and finally the overall shape of the objects that are contained in the compositioni.e. the ... to give the shape the appearance of form.2/ Create the basic form ofthe neck byadding a cylinder to the bottom ofthe eggform.3/ Draw in outline the back ofthe head.Now extend the ellipse...
... re-lationship with a pet. The loss ofthe pet often precipitated an episode of severesymptoms ofthe disorder. Child psychologist Boris Levinson (1970), who pioneered the use of pets in therapy, observed ... feelingstates.SomesaytheirgoalinlifeistoloveandbelovedbyahumanasmuchastheyloveFand are loved byFtheir pet. Pets often live their full lives with their human companions, and profound bereavement at the loss of a cherished pet is ... Curi-ous George and Where the Wild Things Are engage children’s imaginations as theyhelp them to process their eager explorations and fears oftheworld around them. In The Wizard of Oz, Dorothy’s dog...
... the t rees, andfurthermore it will lead to the mutation of conserved motifsotherwise common to the sequence family to which the gene belonged at the time of endosymbiosis. The dissolution of ... of all ofthe enzymes of the pathway (Fig. 4), it is clear that only about half of the enzymes ofthe tricarboxylic acid cycle, the major pathway of carbon metabolism in mitochondria of oxygen-respiringeukaryotes, ... investigate the evolutionofthe enzymes ofthe pyru vate dehydrogenase(PDH) complex, the tricarboxylic acid cycle, and the glyoxylate cycle by examining t he individual phylogenies of the 21 s...
... detect the presence of CPA-like activity in the body extract of the marine annelid S. magnifica. Given that we previ-ously reported the successful use of MALDI-TOF MSfor the initial detection of ... in the analysis of both parts ofthe animal, with a major presence of bands in the body (upper part) versus the crown (lowerpart). In Fig. 3, we show, in the uncombined(Fig. 3A,B) or in the ... 2009 The Authors Journal compilation ª 2009 FEBS 4881 ases that catalyze the hydrolysis of peptide bonds at the C-terminus of peptides and proteins. They belongto the catalytic classes of either...
... SDS/PAGE [15].Assay ofhuman PKIb activity The activity of purified human PKIb was assayed by the inhibition ofthe catalytic subunit of cAPK in a 50 lLreaction containing 0.5 units of purified catalytic ... gene of human PKIb (Genbank accession number AF225513)has been cloned for the first time based on thehuman fetalbrain cDNA library in our laboratory [11].To explore further the structure ofhuman ... regulation ofthe PKIand PKI isoforms ofthe inhibitor protein ofthe cAMP-dependentprotein kinase. J. Biol. Chem. 272, 20011–20020.20. Byler, D.M. & Susi, H. (1986) Examination ofthe secondarystructure...
... is the cornerstone of the RNA World. Nevertheless, there is a lot going for the RNA World (Bernhardt summarizes much ofthe evidence, and I add more below)whereas the other hypothes es on the ... protein evolution existedalready at the late stages ofthe hypothetical RNA World [92].All this discussion is not pointless play with hypotheses. Realization of the unique status ofthe RNA World ... 7:23 Page 7 of 10http://www.biology-direct.com/content/7/1/23 CO M M E N T Open Access The RNA world hypothesis: the worst theory of the early evolutionof life (except for all the others)aHarold...
... promote the formation of lipid droplets. However, the detailed roles ofhuman CIDEC in the dif-ferentiation ofhuman adipocytes remain unknown. In the present study,we found that the expression of ... between the 14th and 16thweeks of gestation in humans, and that the second tri-mester of gestation is the critical period in adipogenesis.After the 23rd week of gestation, although the number of ... than lipid droplets. The expression of CIDEC is elevated during the differentiation of adipocytesTo gain further insight into the roles of CIDEC inadipocyte differentiation, human primary pre-adipo-cytes...
... Acceleration ofthe cis–trans isomerization ofthe peptide results in the collapse of theseresonances into a single set of peaks. (D) Binding, but not isomerization, ofthe N-terminal peptide of PPWD1. ... interactions between the backbonenitrogen of Glu485 with the oxygen of Gly551, the side-chain of Glu485 is nestled in a deep pocket of the enzyme (Fig. 3B). An oxygen ofthe c-carboxyl groupforms ... oxygen of Lys488 ofthe QAEGPKRpeptide (Fig. 3A), and Phe540 is coordinating Lys488through a stacking interaction. The other interactionsbetween the side-chain ofthe QAEGPKR peptide in the active...
... description ofthe size ofthe fund industry across the world. B. Description oftheWorld Fund Industry Table I provides a description ofthe size ofthe mutual fund industry across theworld at the ... in light of varying institutional arrangements used around the world. The second section describes the sources of our data on theworld fund industry and provides a brief sketch ofthe industry. ... The regulation and supervision of banks around the world: A new database, World Bank working paper. Bhattacharya, U., and H. Daouk, 2002, Theworld price of insider trading, The Journal of...
... the replicase gene of viruses in 7 ofthe 8genera ofthe Tombusviridae [24]. This division ofthe rep-licase ofthe Tombusviridae by a termination codon isthought to be part of a translational ... Addi-tionally, the presence of an amber stop codon (nt position1230–1232) at the end of ORF 1 ofthe SOG genome (Fig-ure 2C), resembles the in-frame termination codon char-acteristic ofthe replicase ... content of the SOG genome is 52%.We identified the eight conserved motifs ofthe RdRp [11]in the SOG genome (aa residues pos 451 to 700) (Figure2C). tBLASTx [12] searches with the remainder of the genome...
... performancefor these ratios traditionally was considered as well in excess of 1:1, with the higher the better. The greater the margin of cur-rent assets over current debt, the better the position ofthe ... discusses these challenges in the context ofthe twenty-first century “new” economy from the perspectives ofthe working CFO rather than the textbook CFO.Why the new economy? And what’s wrong with the ... 0-471-20997-XPrinted in the United States of America10 9 8 7 6 5 4 3 2 1 26 THE REAL WORLDOF FINANCEmarketing organizations in theworld have developed the dataand the discipline for their salespeople...
... survivingfraction of treated cultures was calculated by dividing the number of colonies by the plating efficiency of untreatedcells. The survival curve was established by plotting the log ofthe surviving ... calculated area of additive treatment response (envelope of additivity) [52]. The given results ofthe experiments were then comparedto the calculated data: values within the envelope of addi-tivity ... participated in the conception of the study and interpretation of data. VJ performed conceptionand design ofthe study and substantially contributed tointerpretation of data, drafting ofthe manuscript,...