... ofthe study and the revision ofthe manuscript JB participated in the design ofthe study, appraised the guideline with eGLIA, and participated in the telephone conference and the revision of ... Sweden, the Netherlands, and New Zealand Appraisal ofthe guideline We asked the panel members to read the ESHRE guideline for the diagnosis and treatment of endometriosis and to assess it with the ... was boring and too time consuming Table Process evaluation of eGLIA Questions (n = 10) Answers D N A The explanation ofthe GLIA dimensions is clear 2 The explanation ofthe use ofthe eGLIA tool...
... the tenants, on the one hand, and the staff, volunteers and visitors, on the other hand, in their day-to-day chores This study therefore hopes to look at the language and literacy practicesof ... and 13 Erving Goffman) in order to permit a sophisticated and textured account of notions of power and identity, on the one hand, and their linkage with practicesof literacy, on the other hand ... ‘basic’, the social meaning of literacy: that is, the roles these abilities play in social life; the varieties of reading and writing available for choice; the contexts ofthe performance; and the manner...
... legislation ofthe entire world), but was an animal-man: man in the animal and the animal man 56 Many of inhumane crimes have been justified by the use of dehumanizing rhetoric For example in 1936, the ... neither treated as human beings nor animals – but as a separate species, the “animal man.” 51 Thus, for him, devaluing ofhuman life is the dehumanizing of individuals I find the dehumanizing of ... make the scenario depicted in The Island possible In order to analyze how The Island explores and critiques the commodification ofthehuman body, I will use the Foucauldian theories ofthe docile...
... legislation ofthe entire world), but was an animal-man: man in the animal and the animal man 56 Many of inhumane crimes have been justified by the use of dehumanizing rhetoric For example in 1936, the ... neither treated as human beings nor animals – but as a separate species, the “animal man.” 51 Thus, for him, devaluing ofhuman life is the dehumanizing of individuals I find the dehumanizing of ... make the scenario depicted in The Island possible In order to analyze how The Island explores and critiques the commodification ofthehuman body, I will use the Foucauldian theories ofthe docile...
... authority and hierarchy, the submission of rights and interests ofthe individual under the collective, the important of consent, the avoidance of confrontation, face-saving and generally the supremacy ... my teacher and his family.’ Then she turned to me and said, ‘Teacher, this is my father, mother and grandmother’ I noted the loan word from French that meant ‘father’ as I shook hands and turned ... ofthe literacy practicesof English as a foreign language and Cambodian young adult learners’ identity country to ensure the survival of Cambodianness Failure would shame them and their ancestors...
... performance They often see themselves as team leaders, as inspirational rather than directive Many of these women see themselves as working to coordinate and balance their interests and those of their ... ideas into a book Most ofthe interviews and the organization ofthe book were due to the work of Laurel Ofstein, Assistant Director ofthe Leo V Ryan Center for Creativity and Innovation at DePaul ... What is the test of a healthy organism? That it can sustain itself And that it can sustain others When sustainability is the goal and test of leadership, the nature of leadership changes And when...
... helix ofthe CTD which pack against the N-terminal end of helix ofthe NTD of a neighboring subunit in the hexamer Additional contacts involve helix 11 ofthe CTD and the C-terminal end of helix of ... [32], and ofthe mature capsids of different retroviruses; (c) the different structural organization of CA in the immature and mature capsids, including the arrangement and spacing ofthe hexameric ... and they appear to be unusually flexible themselves Accordingly, there is substantial evidence for the occurrence of different conformational rearrangements of CA during the assembly of both the...
... mutants E187A and N183A: the conformations ofthe two assembly-incompetent mutants (Y169A and L211A) in the absence of CAI are the same as the structures of any mutant when complexed to the peptide ... close to the CTD Thus, these peptides and small organic molecules, together with the structures ofthe complexes that they form with CA, provide an important basis for the design of new anti-HIV-1 ... Interestingly, Glu187 (together with Ser178, Glu180 and Gln192) is one ofthe residues that decreases the association constant of CTD, as previously demonstrated in an alanine scanning ofthe dimerization...
... bridging the metal centre to the ligand are shown as magenta and cyan spheres, respectively that the minimal functional unit in the ACMSD enzyme is a monomer and the biological significance, if any, of ... stereochemistry ofthe model has been assessed using the program procheck [23] Ninety per cent ofthe residues fall in the most favoured regions ofthe Ramachandran plot, with Asn148 and His269 falling ... as the amino acid numbers The alternative conformations ofthe Trp–Met couple can be observed; the arrows indicate the unidirectional movement ofthe two protein residues upon ligand binding The...
... the goal is to elucidate the metallation mechanisms ofthe individual domains, in the hope, initially, of simplifying the interpretation ofthe metallation details ofthe two-domain protein The ... in the case of a noncooperative metallation mechanism The metallation rate of either the cooperative or noncooperative process would depend on the preliminary conformation ofthe protein and the ... spectra on the right side of Fig are the deconvoluted spectra showing the mass and identity ofthe species detected The deconvoluted spectra on the right side of Fig clearly show the formation of intermediate...
... blocked the 3889 Mapping of transcobalamin using antibodies S N Fedosov et al Table Specicity of monoclonal anti- (human transcobalamin) sera and their effect on the functional properties of transcobalamin ... proteolytic cleavage ofthe recombinant TC during expression ofthe protein in yeast and plants provided an opportunity to examine the antigenic properties of these peptides The results of western blotting ... conclusion The other antibodies in this assay did not hinder the interaction of TC with Cbl at all (Table 3) and therefore we cannot draw any conclusions on the involvement ofthe other parts of TC...
... maintenance Acknowledgements The authors thank Dr G M C Janssen, for the gift ofthe polyclonal eEF1A antibody and the eEF1A cDNA cloned into pET11a expression vector, and Prof G Manzini, for the ... proteins and lg of polyclonal anti-eEF1A (lane 4), with nuclear proteins and 0.9 lg of polyclonal anti-eEF1A (lane 5), with nuclear proteins and lg of total CRS (lane 6), with nuclear proteins and ... subunits of eEF1 are predominantly located in the cytoplasm, a considerable fraction ofthe a subunit can be found either in the cytoplasm or the nucleus [35,36] The involvement of eEF1A in the regulation...
... single theorem that is the aggregate effort of many hundreds of mathematicians The “proof” is in fact the union of hundreds of papers and tracts spanning more than 150 years At the moment this proof ... ofthe main purposes ofthe present book is to present and examine all these many forms of mathematical proof, and the role that they play in modern mathematics In spite of numerous changes and ... from the center ofthe sun to the planet will sweep out area at a constant rate The square ofthe time for one full orbit is proportional to the cube ofthe length ofthe major axis ofthe elliptical...
... workstation and was based on the structures ofthehuman and porcine pancreatic lipases for the open form and on the horse pancreatic lipase for the closed form [16,18,19,30] For homology modeling, the ... established Of two possible dimeric structures of LPL, the head-tohead and the head-to-tail models, the studies ofthe chimeric proteins of hepatic lipase and LPL and the tandem repeat approach of LPL ... the INSIGHT II program and were based on the crystal structures ofthe human, porcine, and horse PLs (Fig 1) A frontal view illustrates the overall saddle shape ofthe dimeric structure and the...
... we have studied the interaction of ATP and analogues with thehuman pancreatic enzyme with the aims of: (a) presenting experimental evidence for equilibrium binding to the ligand-free super-open ... precluded an estimate of equilibrium thermodynamic parameters, and thus also measurement ofthe effect of ligands on such conformational equilibria Effect of ATP and Glc on extrinsic ANS fluorescence and ... mutant L146R GST–hGK The enhancement of ITF was measured at 25 °C with increasing concentrations of Glc in the absence (d) and presence (s) of 2.5 mM ATPcS The solid lines represent the fit of the...
... dedicated to the furtherance of science and technology and to their use for the general welfare Upon the authority ofthe charter granted to it by the Congress in 1863, the Academy has a mandate that ... means of accelerating the necessary assessment ofthe appropriateness, effectiveness, and value of medical care; and the policy changes necessary to improve the efficiency and outcomes ofthe ... by the authors to document the proceedings ofthe 2007 IOM Annual Meeting EVIDENCE-BASED MEDICINE ofthe national domestic agenda, the choice of EBM by the IOM Council as the theme of the...
... scientific and engineering research, dedicated to the furtherance of science and technology and to their use for the general welfare Upon the authority ofthe charter granted to it by the Congress ... schools of forestry, historically African American land grant institutions, colleges of veterinary medicine, colleges ofhuman sciences, Native American land grant institutions, and Hispanic-serving ... to track thechanging structure of agriculture The other drivers and determinants of structural change are numerous: pressure from consumers and end-use markets, changing demographics and work...
... one in the center ofthe hexameric ring and another in a trilobed hole flanked by the hexamer spokes [72] Although the mechanism of restriction is still unclear, reverse transcription ofthe viral ... model ofthe PRYSPRY domain ofhuman TRIM5a using the known structures ofthe same domain from three other proteins [66–68] Furthermore, these authors showed that alanine mutations at clusters of ... presence of CyPA [48] The exact role of CyPA in the viral lifecycle is unclear and remains a subject of intense debate [49– 51] The significance of this interaction is supported by an alignment of primate...
... and resulted in an alternate protein with 7–8 residues less than human PKIb [11,19] Conformation ofhuman PKIb from FTIR, Raman and CD Absorbance spectrum and the second derivative spectrum of ... structure of protein and one might expect the above solution structure to be reflected in Fig The 1652 and 1270 cm)1 bands can be assigned to a-helix in thehuman PKIb; the 1666 and 1247 cm)1 bands ... which is consistent with the result obtained through infrared spectroscopy CD spectrum of thermal unfolding and refolding ofhuman PKIb The conformational changes ofthehuman PKIb were monitored...