... Arthritis Research & Therapy Vol 11 No Mahler and Fritzler Comments on the report of Hanke and colleagues Hanke and colleagues are the first to report the use of a novel LIA for the simultaneous ... incremental clinical value to the diagnosis and management of SSc patients Comparison with other methods: quality of PM/Scl-100 For reasons described above and in the closing below, the authors’ conclusion ... number of SSc patients that are positive for PM/Scl aabs likely requires elucidation and further study Page of (page number not for citation purposes) The findings of Hanke and colleagues are of...
... by the Governing Board ofthe National Research Council, whose members are drawn from the councils ofthe National Academy of Sciences, the National Academy of Engineering, and the Institute of ... Academy of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health ofthe public The Institute acts under the responsibility ... engineering research, dedicated to the furtherance of science and technology and to their use for the general welfare Upon the authority ofthe charter granted to it by the Congress in 1863, the Academy...
... modern-day mentor to bounce ideas off of and, like other women at the top of their profession, sees the loneliness ofthe position as one ofthe few downsides to the job Although she loves people ... different But these women and the others we have studied also demonstrate the ability to make the most of their talents given the situations in which they find themselves and many demonstrate the ability ... right there [pointing to a framed picture on the wall of her of ce]—he was then the Chief Hearing Of cer for the Commerce Commission Today he’s the Women in Business Illinois Supreme Justice for the...
... bullet-proof fashion that will stand the test of time The second, and for the working mathematician the most important, aspect of proof is that the proof of a new theorem explains why the result ... the bulk of their time proving theorems, it is nevertheless the case that proof is the lingua franca of mathematics It is the web that holds the enterprise together It is what makes the subject ... What Does a Proof Consist Of? 0.5 The Purpose of Proof 0.6 The Logical Basis for Mathematics 0.7 The Experimental Nature of Mathematics 0.8 The Role of Conjectures ...
... Academy of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health ofthe public The Institute acts under the responsibility ... as the prospect of new ways of meeting the need, provides the back-drop for the discussions at the 37th Annual Meeting ofthe Institute of Medicine (IOM) Entitled Evidence-Based Medicine and the ... president ofthe Institute of Medicine The National Research Council was organized by the National Academy of Sciences in 1916 to associate the broad community of science and technology with the Academy’s...
... Transportation ofresearch animals is an essential component oftheresearch enterprise The integrity and well-being ofthe animals being transported are necessary for the quality oftheresearch and the ... Academy of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health ofthe public The Institute acts under the responsibility ... by the Governing Board ofthe National Research Council, whose members are drawn from the councils ofthe National Academy of Sciences, the National Academy of Engineering, and the Institute of...
... methylmalonyl-CoA alone, there was no evidence for the methylmalonyl derivative ofthe chain-extension ACP, despite the presence ofthe free thiol form ofthe domain The nature ofthe diketide adduct ... suppression of iteration and the maintenance of fidelity of reduction In the presence of all the (natural) substrates required for diketide synthesis on the DKS, the relatively high level of loading of ... addition, specific ejection ofthe phosphopantetheinyl prosthetic group from the ACP can be induced in the mass spectrometer, allowing highly accurate determination ofthe mass ofthe attached species...
... change, the lengthening of shots before them may prepare the viewer for that change, and the shortening of shots after can accelerate the viewer into the new scene Notice first that the pattern of ... after it in the sequence of transitions across the film Data points represent the mean of 10 film medians for each of 15 sample years, 1935-2005 The lower panel shows the median length ofthe longest ... clusters the Hollywood montage; Salt (2009, p 194) called them the “classical” montage Consider first the changes in the use ofthe single dissolve Single Dissolves The upper panel of Figure shows the...
... made of a synthetic leather causing them to be more responsive in the dribble The first professional basketball league formed was the National League and it consisted of six teams When the National ... forwards Bob Cousy was the first showman ofthe NBA and many followed his act until it became normal procedure among players It is almost painful to think ofthe tempo ofthe game before Bob Cousy ... from the opposing teams "Dr J" changed what was just two points into a massive rush of adrenaline He did not have a great outside shot but he could hang in the air with the best of them The condition...
... and the full wardrobe of clothes and accessories that were “dominant on every campus where attention to the niceties in the matter of dress is the rule rather than the exception” the r ise ofthe ... review of media influences, most ofthe harmful effects ofthe media involve the adoption of impulsive behavior patterns that maximize short-term reward at the expense of long-term gain The media’s ... identifying the effects of newspaper reports of suicide as a source of contagion with the well-publicized death of Marilyn Monroe often cited as an example Other research has extended the phenomenon...
... for many ofthe predictions, since neither the primary sequences nor the domain features ofthe unannotated genes played a part in the predictions In many cases, the domains also augment the predicted ... with the online version ofthe article (c) Comparison ofthe overall predictive capacity of three data sets, restricted to the 13 tissues and 1,800 genes shared by all three data sets Each ofthe ... precision of 30% To estimate the significance ofthe colored lines, we repeated their calculation after permuting the gene labels in the annotation database The dotted black line indicates the maximum...
... and the average amount of mast was determined The plots were selected randomly in the oak stand and the number of acorns was determined on each ofthe plots The acorns were then hulled and the ... stands In the present paper, the population dynamics of As is described in larger forest complexes of southern Moravia depending on the biotope and food supply including the response ofthe population ... (Pelikán 1964, 1976) At present, the problem ofthe ecology of As research in forest ecosystems is in the background by reason of rather difficult differentiation from the more abundant A flavicollis...
... applications The attendance was unusually low this year, especially on the industry side, witnessing the tight economic situation in the USA and internationally At the same time, thechanging focus ofthe ... alerting the prey The use of modern genomics tools in the population genetics of language evolution illustrates how diverse the genomics field has become, and that, in fact, the maturity of genomics ... Vidal’s group has currently completed 10% ofthe interactome matrix, and is moving towards completeness with the goal of understanding not only the components ofthe interactome but also protein behaviors...
... (C) The colours indicate the base pair probabilities The accumulation of red collared base pairs indicates the high reliability ofthe estimated consensus structure The free energy ofthe thermodynamic ... expressed at the late stage ofthe infection cycle Thereby they identified putative σ28 promoters upstream of ltub and the annotated ORF CPn0332 According to the identified TSS the putative σ28 ... consistent with the TSS are present in all of these genes For example, the heat shock transcriptional regulator HrcA is encoded as the first gene ofthe dnaK operon and starts bp downstream ofthe annotated...
... the Health Professions in Toronto, Canada Conclusions The growing field of genomics provides the most visible example ofthe explosion of medical data, but it is still only one component ofthe ... to meet the challenges ofthe information explosion The skill set ofthe entering medical student needs to be refined accordingly As current US medical students make the transition into their individual, ... processes, the application of emerging information and how new knowledge is developed Certainly the application of these skills requires a backbone of medical facts and relationships, but these facts...
... RECs; and certification of REC members Whether a single strategy or a combination of strategies is pursued, the goal should be to reinforce ofthe professionalism of human research review [23] in ... For REC members, researchers, subjects and the public at large to have justifiable confidence in the ethics of human research and the role of RECs in reviewing protocols, issues of accountability ... Looking to the future Competing interests The relationship between RECs and researchers can sometimes be quite divisive The advancement of ethical research is curtailed if the efforts of RECs are...
... the proportion of sequences that are shared with one or more members ofthe same domain The numbers in the overlapping regions ofthe diagram show the proportion of sequences shared between the ... analysis of genes from fully sequenced genomes On the basis of a raw BLAST score cutoff of 50, we determined the number of sequences with similarity of sequences derived from the three domains of life ... clear grouping of genomes into the three domains of life (as indicated on the left ofthe figure) with the exceptions of Cryptosporidium parvum (placed by itself outside the main group of eukaryotes)...
... take into account the number of probes (weight) that went into the calculation ofthe spectral power The family of null distributions was calibrated from the distribution of scores of all probes ... degradation [53] Therefore, the absence of a reciprocal expression pattern ofthe target transcripts does not rule out a specific function behind the circadian behavior ofthe miRNA The well-described ... we plot the results ofthe spectral analysis ofthe expression level time course for individual features on the array Each of these genes had at least two exon features that satisfied the p