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the capital city of the cakchiquels

Tài liệu The King''''s Post Being a volume of historical facts relating to the Posts, Mail Coaches, Coach Roads, and Railway Mail Services of and connected with the Ancient City of Bristol from 1580 to the present time pdf

Tài liệu The King''''s Post Being a volume of historical facts relating to the Posts, Mail Coaches, Coach Roads, and Railway Mail Services of and connected with the Ancient City of Bristol from 1580 to the present time pdf

Cao đẳng - Đại học

... affair is a copy of part of Gascoigne's account, of which the following is a transcript:— [Pg 20] THE OFFICE OF THE POSTE. In the office of William Dodington, Esquire, Auditor of Her Matie. ... forward in the street; on the east side being another building answerable thereto." These premises served as the Post Office for the long period of 118 years. The first half of the present ... parcel of ground situate in the Parish of St Werburgh in the City of Bristol on the South West side of and fronting to Small Street aforesaid specified in the plan drawn in the margin of the first...
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Tài liệu Facing Human Capital Challenges of the 21st Century ppt

Tài liệu Facing Human Capital Challenges of the 21st Century ppt

Khoa học xã hội

... improve the human capital or skills of a country’s population, or to facilitate the employ-ment of human capital in diverse sectors of the economy. Table 1.1 provides the categories of reforms ... interest in human capital and economic initiatives.12 Facing Human Capital Challenges of the 21st CenturyWe used the interview notes to provide an overview of the areas of human capital deficits ... arguably the most comprehensive in the region; changes initiated in 2002 address the management and delivery of educational services, the curriculum, and the quality of teachers and other critical...
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Tài liệu Báo cáo khoa học: Substrate specificity of the pseudouridine synthase RluD in Escherichia coli doc

Tài liệu Báo cáo khoa học: Substrate specificity of the pseudouridine synthase RluD in Escherichia coli doc

Báo cáo khoa học

... obtained with the transition at posi-tions 1915 and 1917. These mutations had an effect on the formation of pseudouridine exclusively at the mutant position and did not affect either of the othertwo ... bySouthern analysis. The rluD::cat strain had a full deletion of both rluD and yfiH, together with their annotated pro-moter sequences. The inserted cat cassette had a distance of 90 nt from the ... primer extension. The primer exten-sion stop on the CMCT treated RNA (+ lane)indicated the presence of pseudouridine at the particu-lar position when the stop was not present in the con-trol...
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Tài liệu Báo cáo khoa học: Ionic strength and magnesium affect the specificity of Escherichia coli and human 8-oxoguanine-DNA glycosylases pdf

Tài liệu Báo cáo khoa học: Ionic strength and magnesium affect the specificity of Escherichia coli and human 8-oxoguanine-DNA glycosylases pdf

Báo cáo khoa học

... for the opposite-base speci city of Fpg andOGG1. Also, although the buffering capacity of KGluat pH 7.5 is much weaker than that of KPi, the omission of KPihad a rather minor effect on the ... Fig. 2. In the absence of MgCl2, the affinity of Fpg for the THF:C ligand was 1.6-fold higherthan for the THF:A ligand. The presence of Mg2+hadlittle effect on the binding of Fpg to the THF:C ... 0–5 mm MgCl2. The C ⁄ A speci- city of the glycosylase reaction in the absence of KPiwas usually higher than in the presence of KPidue toless efficient cleavage of 8-oxoG:A; the highest specific-ity...
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Tài liệu Báo cáo khoa học: An investigation of the substrate specificity of the xyloglucanase Cel74A from Hypocrea jecorina pdf

Tài liệu Báo cáo khoa học: An investigation of the substrate specificity of the xyloglucanase Cel74A from Hypocrea jecorina pdf

Báo cáo khoa học

... presumably, contain the sites of O-glycosylation,but we have not identified the specific site(s) or the form of the O-glycans. The CD spectrum of Cel74A looks a lot like that of an unordered protein ... 4, and may be the basis for the unique mode of action of this enzyme.More definitive statements await the solution of the Cel74A structure, which is currently underway.Conclusions The xyloglucanase ... incubation with Cel74A, and the proposed cleavage pattern (C) with the theoretical m ⁄ z value (z in superscript) of the most important fragments (the position of the Gal residues is arbitrary)...
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Tài liệu Báo cáo khóa học: Active-site residues and amino acid specificity of the bacterial 4¢-phosphopantothenoylcysteine synthetase CoaB pptx

Tài liệu Báo cáo khóa học: Active-site residues and amino acid specificity of the bacterial 4¢-phosphopantothenoylcysteine synthetase CoaB pptx

Báo cáo khoa học

... hasFig. 5. Analysis of the enzymatic activity of His-CoaB R206Q and A276V. The synthesis of 4¢-phosphopantothenoyl-CMP (–cysteine, upper part of the figure) and of 4¢-phosphopantothenoylcysteine (+ ... synthesized in five steps fromD-pantothenate. The Dfp flavoprotein catalyzes the synthe-sis of the coenzyme A precursor 4¢-phosphopantetheinefrom 4¢-phosphopantothenate and cysteine using the ... formation of 4¢-phosphopantothenoyl-CMP (activation of the carboxyl group of 4¢-phosphopantothenate). In a second step, the amide bond of PPC (shaded in grey) is formed by reaction of 4¢-phosphopantothenoyl-CMP...
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Báo cáo khoa họcRe-engineering the discrimination between the oxidized coenzymes NAD+ and NADP+ in clostridial glutamate dehydrogenase and a thorough reappraisal of the coenzyme specificity of the wild-type enzyme docx

Báo cáo khoa họcRe-engineering the discrimination between the oxidized coenzymes NAD+ and NADP+ in clostridial glutamate dehydrogenase and a thorough reappraisal of the coenzyme specificity of the wild-type enzyme docx

Báo cáo khoa học

... than the true value, underlining the impact of quite asmall level of contamination on these results.Reassessment of the effects of the mutations oncoenzyme speci city In view of the dramatically ... moiety of the coenzyme resultingfrom splitting off the nicotinamide ring, suggestingthat the covalent bond between the nicotinamide and the ribose of the coenzyme is particularly labile. The signal ... thatapparent rates of NADP+utilization mainly reflected the reduction of con-taminating NAD+, creating an entirely false view of the initial coenzymespeci city and also of the effects of mutagenesis....
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Báo cáo khoa học: by nucleotide affinity cleavage: a distinct nucleotide specificity of the C-terminal ATP-binding site potx

Báo cáo khoa học: by nucleotide affinity cleavage: a distinct nucleotide specificity of the C-terminal ATP-binding site potx

Báo cáo khoa học

... applicability of the nucleotide affinity cleavagetechnique to study the speci city of the nucleotide bindingsites. Since GTP is a C-terminal-specific nucleotide, wefurther analyzed the properties of Hsp90 ... an intact adenine ring; the stick model is the structure of the kinked ADP in the Hsp90 crystal, the phosphates pointing out of the domain;Rstandsforphosphates(ATP)orothermoietiesasinNADor adenosine ... of ADP [20]. The reason for thismay be that the ATP-bound resin may impose a sterichindrance to the binding of the terminal phosphate,therefore Hsp90 adopts an ÔADP-conformationÕ [20] onthe...
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Báo cáo khoa học: Structural basis for the erythro-stereospecificity of the L-arginine oxygenase VioC in viomycin biosynthesis docx

Báo cáo khoa học: Structural basis for the erythro-stereospecificity of the L-arginine oxygenase VioC in viomycin biosynthesis docx

Báo cáo khoa học

... conformers of the substrate are suitablyoriented to point with the proS-hydrogen atom of the Cb group towards the catalytic iron. With an iron–hydroxyl distance of 3.1 A˚, the structure of the VioC•hArg•Fe(II)•succinate ... for the asparagine oxygenase AsnO and other mem-bers of the clavaminic acid synthase-like superfamily. Additionally, the sub-strate speci city of VioC was investigated. The side chain of the ... concerning the adenylation domain(A-domain) speci city of VioF revealed b-ureidoalanineactivation, leading to the proposition of a new modelfor the order of the NRPSs during viomycin biosynthe-sis...
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Báo cáo y học:

Báo cáo y học: "Study of the early steps of the Hepatitis B Virus life cycle"

Y học thưởng thức

... translocation of the internally sequence of PreS1 domain onto the viral surface [62, 63]. This supports the hypothesis that the low pH in the endosome may induce the conformation change of HBV surface ... a result of the variation of loading, because the expression of the thimet oligopeptidase gene in the same condition did not show any difference (Figure 2C). The over-expression of the SPIK ... target, further confirmed the role of LHBs in the HBV attachment [23]. Recently, the attachment site of LHBs was functionally narrowed down to the amino acids 21–47 of preS1 by employing synthetic...
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Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects

Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects"

Y khoa - Dược

... role in the regulation of proliferation, migration, and differ-entiation of the epithelial cells [2,12,18,19]. Following the surgical treatment of adult periodontitis, the epithelial regeneration ... gingivitis grade of 0 or 1. Thanks to the bacteriostatic properties of the tested polymer, a more effective control of the surgical wound no bacterial contamina-tion of the surgical site ... largely responsible for the consistency of the active component that can act as a barrier to the spread of any bacteria penetrating the tissues including those of the periodontium. It is conceivable...
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