the applications of feature based image metamorphosis and eyelashes removal in the investigations of ocular thermographic sequences
nanotechnology for cancer therapy, 2007, p.810
... by the introduction of the first synthetic protein -based drugs In the early 1980s, protein -based drugs offered an entirely new approach to targeting and treating disease They could be “engineered” ... and the stroma; the latter incorporating the vasculature and other supporting cells As the tumor grows, in order to meet the metabolic requirements of an expanding population of tumor cells, the ... nature of the nanoparticle and the mode of administration, there can also be complicating factors that affect the effectiveness of the targeting method Inherent targeting and complicating factors...
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báo cáo hóa học: " In vitro and in vivo pre-clinical analysis of a F(ab’)2 fragment of panitumumab for molecular imaging and therapy of HER1-positive cancers" pot
... radiolabelings TN performed PET imaging and analysis MWB synthesized the chelate and participated in the design of the studies DEM conceived of and coordinated the studies and assisted with the in vivo ... assisted in the drafting of the manuscript, the final version of which has been read and approved by all of the authors Competing interests The authors declare that they have no competing interests ... target, the targeting vehicle, and the radionuclide Based on these earlier reports and the importance of retaining affinity/avidity, the F(ab’) fragment was selected for this investigation as the...
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Surface functionalization of superparamagnetic iron oxide nanoparticles for potential cell targeting, imaging, and cancer therapy applications
... particles On the other hand, the growth of the particles may also be inhibited due to the adsorption of additives on the nuclei and the growing crystals, leading to formation of smaller particles In addition, ... PBS, and artificial urine at 37 oC Inset shows the release profile in the first 10 h Figure 6-9 Size increase of a mixture of Pt-Fe-PNs and mucin after incubation at 37oC for h Pure mucin and ... time of the drug in the bladder, due to the periodical voiding of urine from the bladder which flushes out the instilled drug solution Thus, frequent dosage is required The other limitation is the...
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Molecular Imaging: An Essential Tool in Preclinical Research, Diagnostic Imaging, and Therapy potx
... either a DNA-binding domain (BD) or activation domain (AD), creating hybrid proteins If the hybrid proteins bind to each other as a result of interaction between the proteins of interest, then ... the selection of natural D-ribose aptamers binding to the mirrorimage of the target, such as, for instance, a D-amino acid peptide, followed by the chemical synthesis of the mirror -image of the ... and for the CLuc fragment The optimized combination of fragments produced no signal in the absence of rapamycin and strong bioluminescence in the presence of the dimerizing agent rapamycin In live...
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The use of gold nanostructures in the imaging and therapy of cancer
... absorption or scattering and offer promising clinical application especially in the area of cancer imaging by increasingly proving themselves to offer alternative angles in examining the same biological ... top row of images show the skin on the left of the interface while the bottom row of images show the skin on the right of the interface…………………………………………………… ….233 xxvi Figure 8.4 Liver of male balb/c ... epithelial thickening and changes in stratification and structure of the mucosa during carcinogenesis [15, 51] without the need for tissue removal and sectioning The use of OCT to image cancer in...
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Báo cáo hóa học: " Both FA- and mPEG-conjugated chitosan nanoparticles for targeted cellular uptake and enhanced tumor tissue distribution" docx
... targeting of the NPs can aid in selection of the target cell type within the tumor site and internalization of the NPs to a greater extent inside the target cells A wide variety of tumor targeting ... all kinds of the NPs were labeled by rhodamine B in advance; 0.2 ml suspension of blank NPs at the concentration of mg/ml was administrated by injection into the tail vein of nude mice, and the ... Nevertheless, in case of mPEG-NPs, rhodamine B was significantly localized probably in the outside of the cells instead of a distribution in the endosomes, indicating that the mPEG-NPs tended to reduce the...
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Báo cáo y học: "Rasburicase represents a new tool for hyperuricemia in tumor lysis syndrome and in gout Lisa Cammalleri and Mariano Malaguarnera"
... synthesis, and inosine that will be degraded into hypoxanthine and xanthine and finally into uric acid Hypoxanthine and guanine may enter in a salvage pathway, using hypoxanthine-guanine phosphoribosyltranferase ... hypoxanthine, inhibitor of xanthine oxidase, the last enzyme involved in uric acid synthesis pathway It catalyzes the conversion of hypoxanyhine into xanthine and this latter into uric acid During ... tendency to lowering of pH in patients with vomiting and diarrhoea It increases solubility and renal excretion of uric acid and xanthine, maintaining urinary pH between 7.0 and 7.3 Nevertheless, if...
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Báo cáo khoa học: Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis pptx
... protein-coding genes contain introns that are removed in the nucleus by RNA splicing and are often alternatively spliced Alternative splicing increases the coding capacity of the genome, generating ... heparanase C-domain as the molecular determinant behind its signaling capacity The existence of a C-terminus domain (C-domain) emerged from a prediction of the 3D structure of a single-chain heparanase ... remodeling of the ECM underlying tumor and endothelial cells, thereby facilitating cell invasion [23–25] Progress in the field and the generation of genetic tools (i.e heparanase transgenic and knockout...
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adobe digital imaging how-tos 100 essential techniques for photoshop cs5, lightroom 3, and camera raw 6
... categorizing and applying attributes; comparing similar images in detail; and exporting files to new formats and workflows The Library module is the photographer’s best friend, making the linear ... panel Click the first thumbnail in the series, press and hold Shift, and then click the last thumbnail in the series, then deselect any of the thumbnails to dim them all You can reselect the entire ... by clicking it (look for the white highlight around the edge) (The image on the right side of the Compare view is called the candidate.) Click a new image in the Filmstrip This becomes the new...
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patel, chellapa - sparse representations and compressive sensing for imaging and vision
... plane of the imaging system introduces a phase error in the pupil function that increases the width of a point response and produces an out of focus image The system’s depth -of- field is defined as the ... sparsity, incoherent sampling and non-linear recovery Some of the main results are also reviewed In Sect 3, we describe several imaging modalities that make use of the theory of compressive sampling In ... figure, these coefficients are very sparse The plot of the sorted absolute values of the coefficients of the image is shown in Fig 2.1(c) The reconstructed image after keeping only 10% of the coefficients...
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báo cáo hóa học:" Comparative study of 64Cu/NOTA-[D-Tyr6,beta-Ala11,Thi13,Nle14]BBN(6-14) monomer and dimers for prostate cancer PET imaging" potx
... participated in the coordination of the study and reviewed the manuscript GB conceived of the study, participated in its design and coordination, and helped in making the draft of the manuscript ... influx of the radiotracer from the blood At h after the injection of 64Cu/NOTA-monomer, the radiotracer was still in the form of its parent in the blood suggesting that the increased uptake of ... enhance the local concentration of the other BBN(6-14) unit in the vicinity of the receptor which might facilitate further binding However, statistical rebinding is dependent on the density of receptor...
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Báo cáo y học: "Autologous chondrocyte implantation for cartilage repair: monitoring its success by magnetic resonance imaging and histology" ppt
... the integrity and contour of the articulating surface, the degree of metachromasia with safranin O staining, the extent of chondrocyte cluster formation, the presence of vascularisation or mineralisation ... 2) The 3D images were acquired in the sagittal plane except in the patients with patella grafts, when images were acquired in the axial plane These sequences allowed longitudinal study of the ... to influence mechanical functioning of the tissue and is often of most interest to observers A smooth surface is important for articulation and in the transfer of incident loads throughout the...
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Báo cáo khoa học: "Preoperative Y-90 microsphere selective internal radiation treatment for tumor downsizing and future liver remnant recruitment: a novel approach to improving the safety of major hepatic resections" docx
... in the portal tracts The deposition of the majority of the absorbed dose is within a very tight zone immediately surrounding the microspheres Even though the maximum range of particles in the ... embolization (PVE) has gained wider acceptance to achieve the goal of increasing the volume of the FLR [2] First reported by Makuuchi et al [3], the aim of PVE is to bring about atrophy of the segments to ... hypertrophy Obviously, the major advantage of SIRT is the effective control of the tumor in the target liver lobe The value of initiating chemotherapy concomitantly with Y-90 microsphere administration...
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Báo cáo y học: "Expression of ADAM15 in rheumatoid synovium: up-regulation by vascular endothelial growth factor and possible implications for angiogenesis" ppt
... VEGFR-2 and neuropilin-1 and 65°C for β-actin, and minute at 72°C, followed by minutes at 72°C for the final extension The nucleotide sequences of the PCR primers and the expected sizes of the amplified ... endothelial cells of blood vessels and macrophage-like cells in the sublining layer of the RA synovium (Fig 5a,b), confirming the findings from in situ hybridization No staining was obtained ... [8]; and the recombinant human disintegrin domain of ADAM15 itself exhibits anti-angiogenic activity, probably by disturbing the interaction between ADAM15 and integrins, leading to inhibition of...
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Báo cáo khoa học: "Planning target volume margins for prostate radiotherapy using daily electronic portal imaging and implanted fiducial markers" docx
... are shown in Table 2, in the right-hand columns ("during treatment”) In the figures, any deviation of individual points from the intersection of the x and y axes represents a combination of residual ... the L-R and S-I axes, and mm or larger along the A-P axis, effectively reduced the combined systematic and random error to within mm along the L-R and S-I axes and mm along the A-P axis Our image ... typically involved the ingestion of a specified amount of water at a certain interval prior to treatment, and the use of a mild laxative such as milk of magnesia as needed to maintain a regular...
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Báo cáo khoa học: "Value of diffusion weighted MR imaging as an early surrogate parameter for evaluation of tumor response to high-dose-rate brachytherapy of colorectal liver metastase" docx
... participated in the design of the study and carried out the interventions FWR performed the statistical analysis GG participated in the design of the study and the treatment planning procedures ... conceived of the study and participated in its design and coordination All authors have read and approved the final manuscript Competing interests The authors declare that they have no competing interests ... three slices of the ADC map depicting the largest tumor diameter were selected, depending on the volume of the tumor In each slice a region of interest (ROI) was delineated according to the tumor...
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Báo cáo khoa học: "Stereotactic body radiotherapy for stage I lung cancer and small lung metastasis: evaluation of an immobilization system for suppression of respiratory tumor movement and preliminary results" ppsx
... defined the upper lobe in the right lung and the segment 1+2 and in the left lung as the upper lung field, and the rest of the lung as the lower lung field The tumor movement in the lower lung field ... with CTguided biopsy in patient, this case was included in the study considering the positive FDG-PET finding and the increase in tumor size during observation period Of the 55 lesions, 42 were ... YS indicated the design of the study and gave final approval of the version to be published NT participated in analysis and interpretation of data CIH, KO and SA participated in acquisition and...
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Báo cáo khoa học: " Ipsilateral irradiation for well lateralized carcinomas of the oral cavity and oropharynx: results on tumor control and xerostomia" pot
... invasion in one patient and positive resection margin in the other The objective of adding concurrent chemotherapy in these patients was to increase the loco-regional control probability As the ... and 2) In some cases, where the PTV was more medial, a contralateral field was used to increase the dose homogeneity of the deep part of the target, always sparing the parotid gland The use of ... some of the patients included in the study and participated in the critical discussion of the data AM helped draft the manuscript AG revised the clinical dosimetries All authors improved the manuscript...
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Báo cáo khoa học: " Kinetic modeling of tumor growth and dissemination in the craniospinal axis: implications for craniospinal irradiation" pps
... suspend treatment of the spine temporarily while treatment of the brain continues Since the brain and spine are in communication via the cerebrospinal fluid, holding treatment in one compartment ... the ultimate goal of evaluating and optimizing therapeutic intervention within the contexts of these models [11] In this report we describe a kinetic model of tumor transport in the craniospinal ... levels of N-cadherin were seen in astrocytic tumors that had disseminated via the CSF [28] The values of kshed and kadh may in part be functions of the status of proteins such as the cadherins in...
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Báo cáo y học: "Targeted genomic capture and massively parallel sequencing to identify genes for hereditary hearing loss in middle eastern families" pot
... identified in of the 11 original probands and their families, leading to the identification of causative alleles in 20 additional probands and their families The integration of genomic analysis into ... capture the exons and regulatory regions of 246 genes involved in hearing loss, in human or in mouse The inclusion of genes thus far known to be involved in deafness in the mouse is based on the ... Tables of indels and SNPs in four or more probands in our population (a) Table of indels appearing in four or more probands in our population (n = 11) (b) Table of SNPs in four or more probands in...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25