... in the vicinity ofthe GC-rich strand-switch domain of T cruzi chromosome (Figure 2) Bands of 0.39, 0.34 and 0.31 Mb were detected with probes Tc7 and Tc8, sequences from the left arm ofthe ... homologue of T cruzi chromosome The schematic ofthe 0.51 Mb chromosome shows the position ofthe 11 kb GC-rich strand-switch domain (yellow oval) The expanded section (70 kb) contains the four ... etoposide and mapped the sites of Topo-II activity With chromosome (homologues of 1.15 and 1.2 Mb), probes from the left arm ofthe chromosome (Tb1 and Tb2) hybridized to a major cleavage product of...
... provides an estimate ofthe standard error of 2b andthe statistical significance ofthe intraclass correlation was assessed as the ratio ofthe variance component to its standard error evaluated ... correlations and category differences The magnitude ofthe intraclass correlations usefully standardizes the results for different traits but we have presented the importance of these results in terms of ... below and correlations for the combined L and T lines only are above the diagonal The most noticeable feature ofthe results is the presence of strong correlations between many traits and body...
... that ofthe daN sequential signal) andthe presence of strong dNN cross-peaks, indicated that there was a significant population of conformations in the a region ofthe /w space The presence of ... one single peak andthe expected theoretical mass and were used for the structural analysis (NMR and CD) CD spectra analysis of monomers and polymers, at a concentration where these peptides were ... changes in the native peptide random structure Our results also suggested that the presence of a short helical region between amino acids and 10 (24148), and greater flexibility in the rest ofthe molecule,...
... involved in the design ofthe present study and gave his intellectual input during the drafting process AV was also involved in the conception and design ofthe study, interpretation ofthe data and ... interpretation ofthe data and revising the manuscript critically JT was responsible for the study design and interpretation ofthe data and was involved in writing the manuscript, focusing on the statistical ... presence of interactions between any ofthe DMARD groups andthe maximum used dosages, days of DMARD use and a cumulative variable Because the maximum dosages ofthe different DMARDs are of different...
... writing the article HEV and RWF also contributed to theselectionand inclusion of cases and controls JvdP also contributed to the statistical analysis ofthe data All authors read and approved the ... within the government-initiated healthcare region ofthe city of Enschede in The Netherlands On 31 December 2003 the population con- Page of (page number not for citation purposes) Selectionof controls ... Surgery and Internal Medicine, the nurses and physician assistants at the Department of Gastroenterology, the research nurses at the Department of Rheumatology and Clinical Immunology, andthe coders...
... report associations of each protein with both joint and vascular disease and their risk factors Materials and methods Subjects The cohort of RA patients met the American College of Rheumatology (ACR) ... kilograms divided by the square ofthe height in meters Blood pressure was measured at the time of evaluation History of hypercholesterolemia and hypertension were identified if the diagnoses were ... levels were found at the time ofthe evaluation The percentage risk of coronary heart disease over the next 10 years was estimated using the 'CVD Risk Calculator' based on the Framingham Study...
... drafted the manuscript LP supervised the genotyping of MBL, conceived the discovery study and was involved in the data acquisition, and was involved in the study design and interpretation ofthe ... RF-negative (a) and RF-positive (b) and then according to their cigarette smoking status into never smokers (c) and ever smokers (d) The box plots show the median values and interquartiles, andthe 10th ... see, in the context of smoking status, whether there was an interaction between the MBLhigh genotype and SE, the main genetic risk factor identified for RA In Figure 1, the subgroups of autoantibody-positive...
... admission and at the time of maximum RIFLE class, APACHE III score, SOFA score andthe nonrenal SOFA score, andthe proportion of patients already admitted inhospital to another non-ICU ward Results of ... writing ofthe paper AK helped analyze the raw data set and helped in the design ofthe study RV and DCA helped to design the study and contributed to writing the paper DDB helped with the statistical ... baseline from the MDRD equation) Our use ofthe lowest of these values for any given patient may have lead to a higher estimate of change and therefore a higher estimate ofthe incidence of acute...
... estimation ofthe number of copies of Dm665 that occur in the tips of metaphase chromosomes in diploid tissues The effect of temperature on the morphology and pattern of hybridization of telomeres ... the tips of broken chromosomes These additions serve the role of telomeres in stabilizing the tips against the loss of DNA during replication Moreover, the addition ofthe He-T sequences to the ... combinations of chromosomes with long and short telomeres in the same genetic background The morphology ofthe long and short telomeres found at the tips ofthe X, 2L, and 3R is illustrated in figure...
... Development; andthe National Survey of Children for the Foundation for Child Development andthe National Institute of Mental Health Dr Zill is the author or co-author of a number of widely cited ... He helped the Select Committee on Children, Youth, and Families ofthe U.S House of Representatives to design and produce three editions ofthe Committee's report, U.S children and their families: ... percent of Hispanic children.) On the other hand, in Midwestern and Western states like North Dakota, Utah, Iowa, and Minnesota, upwards of two-thirds of all children reside with both parents The...
... excluding the birds marked at the beginning ofthe study and in the one area where only a minority ofthe population was ringed None ofthe conclusions changed, so we report the results using the full ... four of these, the majority of birds were caught in the first or years ofthe study and are therefore likely to be a representative sample of ages in the population Ringing effort was then focused ... and without the effects of period and year nested within period and also with year as a factor in the fixed model rather than the random model These alternative ways of specifying the model did...
... especially in the areas of anxiety and depression [12] According to the analysis of data derived from the Health 2000 Study, the threshold value of was taken to indicate ill health (the scores of to ... description ofthe protocol before signing it The procedures were according to the ethical standards ofthe responsible committee on human experimentation and with the Declaration of Helsinki, ... andthe degree of these seasonal changes similar to that of winter blues yields the odds ratio of 2.97 for suffering from mental ill-being to a marked extent Ofthe seasonal changes in mood and...
... differences between the target region ofthe respective genes andthe primer sequences used for typing led to the genotyping failure [1,10,11,17] The Dhaka hospital of ICDDR,B, situated in the central ... with the Gouvea primer set, the distribution of rotavirus G-types changed dramatically (Fig 1) Type G1 now accounted for 44.8% ofthe isolates and became the most prevalent genotype, andthe number ... according to the manufacturer's instructions for the extraction of rotavirus RNA from the stool samples Because ofthenatural variation in the rotaviral gene sequences, close monitoring of rotavirus...
... acknowledged The funding sources had no role in the design and conduct ofthe study; collection, management, analysis, and interpretation ofthe data; and preparation, review, or approval ofthe manuscript ... conducted in the subset of patients who were not on statins to assess the contributions of lipid profile variables in the absence of statin treatment To correct for the multiple testing involved, ... triglycerides and lower LDL than healthy controls [20] However, only limited information is available on the effect of serum triglycerides and cholesterol levels andthe roles of HDL and LDL levels...
... assess the strength of association between the low ficolin-3 and high CRP levels on the one hand andthe unfavorable outcome ofthe disease on the other hand, we repeated the analysis as above in the ... indirect measure ofthe severity ofthe stroke, the concentration ofthe S100β in the follow up samples as an indicator ofthe infarct size, andthe outcome ofthe disease assessed by the modified ... detection in these assays is ng/ml of ficolin-2 and ng/ml of ficolin-3 The inter-assay coefficient of variation (CV) is 7.1% and 4.7% andthe intra-assay CV 4.3% and 3.9% for the ficolin-2 and ficolin-3...
... was reported that the accumulation of point mutations in VP4 and VP7 genes was the main cause ofthe failure ofthe G or P-typing of rotavirus strains [7,8,12,16-21] At least, there are four multiplex ... out of 121 G1 strains from lineage I showed the four specific mismatches at the 5' end ofthe 9T1-1 primer This was associated with the failure of genotyping of G1 strains from Bangladesh Two of ... showing the four lineages described in genotype G1 of rotaviruses The strains having the four mutations reported by Rahman and his colleagues are indicated by ●; the four mutations plus others at the...
... differences between the target region ofthe respective genes andthe primer sequences used for typing led to the genotyping failure [1,10,11,17] The Dhaka hospital of ICDDR,B, situated in the central ... with the Gouvea primer set, the distribution of rotavirus G-types changed dramatically (Fig 1) Type G1 now accounted for 44.8% ofthe isolates and became the most prevalent genotype, andthe number ... according to the manufacturer's instructions for the extraction of rotavirus RNA from the stool samples Because ofthenatural variation in the rotaviral gene sequences, close monitoring of rotavirus...
... specimens, and analyzed and interpreted data PD conceptualized and designed the experiments, analyzed and interpreted data, and helped with the drafting of manuscript JM conceptualized and designed the ... conceptualized and designed the experiments, collected, assembled, analyzed and interpreted data, and drafted the manuscript OC conceptualized and designed the experiments, and collected, assembled and ... analyzed and interpreted data, and helped with the drafting of manuscript All the authors in this manuscript have read and approved the final version Competing interests The authors declare that they...
... evidence that the association between albumin and hsCRP, andthe hazard of death was non-linear (p < 0.10), and there was evidence that the association between albumin andthe hazard ofthe combined ... collection and analysis, decision to publish, or preparation ofthe manuscript The content is solely the responsibility ofthe authors and does not necessarily represent the official views ofthe National ... start therapy the same day; met the BMI and/ or CD4 + threshold criteria; and agreed to adhere to the study visit schedule and laboratory testing requirements At the enrolment visit andthe subsequent...
... regardless of sound source recognition On the other hand, the powerfulness impressions of both the sound and onomatopoeic stimuli were quite different, regardless of sound source recognition For the ... unpleasantness) However, the factor scores for the onomatopoeic representations ofthe same sound stimuli were not as positively or negatively high On the other hand, the factor scores for the “major” onomatopoeic ... also shows that the averaged factor score differences between the real sound stimuli and both the major and minor onomatopoeia were the smallest for the clearness factor Furthermore, the correlation...