test isometric exercise test and angiotensin ii sensitivity test

Báo cáo khoa học: Synergistic co-operation of signal transducer and activator of transcription 5B with activator protein 1 in angiotensin II-induced angiotensinogen gene activation in vascular smooth muscle cells potx

Ngày tải lên : 30/03/2014, 02:20

... AGCTTCTGCTTACCTTTAGCTCCAGCC-3¢ (HindIII site underlined), digested by KpnI and HindIII, and then inserted into the pGL3-basic luciferase reporter gene vector (Promega, Madison, WI, USA) linearized by KpnI–HindIII and named ... with Ang II, the effect of Ang II on the phosphorylation of STAT5 and c-Jun was measured Ang II stimulated the phosphorylation of STAT5B and c-Jun, with levels of phosphorylated STAT5B and c-Jun ... expression of the AGT gene [10], and Ang II activates JAK-STAT and AP-1 [23] To determine the relationship between the activation of STAT5B and c-Jun, and STAT5B and AP-1 interaction in AGT gene...

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Báo cáo y học: "PLCb1-SHP-2 complex, PLCb1 tyrosine dephosphorylation and SHP-2 phosphatase activity: a new part of Angiotensin II signaling?" ppt

Ngày tải lên : 10/08/2014, 05:21

... silencing Figures 4D and 4E present the % change relative to RGS-2 intact and Figure Effect of Ang II on PLCb1-Tyr-phosphorylation and SHP-2 association in RGS-2 silenced and not silenced cells ... dephosphorylation and inhibition in response to Ang II via Ang II type receptor activation [11], therefore activating or prolonging RhoA-Rho kinase pathway’s activity On the other hand, Ang II type receptor ... signaling system and RhoA-Rho kinase pathway [13,15-18] and activation of Ang II type receptor signaling [19] to the complex’s levels and behavior in hypertensive patients, which have Ang II signaling...

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Báo cáo y học: "Genetic polymorphism of ACE and the angiotensin II type1 receptor genes in children with chronic kidney disease" pps

Ngày tải lên : 11/08/2014, 03:20

... size 190 bp and 490 bp for I and D allele respectively Hence, single bands of 190 and 490 bp confirmed homozygous II and DD genotypic state respectively, whereas two bands of 190 and 490 bp confirmed ... deleterious effects of angiotensin II that is, cardiac and vessel hypertrophy including extracellular matrix production In addition to the conversion of angiotensin I to angiotensin II, ACE inactivates ... comparison test Allele and genotypic frequencies for ACE and AT1R alleles were calculated with the gene counting method Hardy-Weinberg equilibrium was tested by using the Pearson Chi-square (X2) test...

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Báo cáo y học: " Genetic polymorphism of ACE and the angiotensin II type1 receptor genes in children with chronic kidney disease" pot

Ngày tải lên : 11/08/2014, 06:23

... size 190 bp and 490 bp for I and D allele respectively Hence, single bands of 190 and 490 bp confirmed homozygous II and DD genotypic state respectively, whereas two bands of 190 and 490 bp confirmed ... deleterious effects of angiotensin II that is, cardiac and vessel hypertrophy including extracellular matrix production In addition to the conversion of angiotensin I to angiotensin II, ACE inactivates ... comparison test Allele and genotypic frequencies for ACE and AT1R alleles were calculated with the gene counting method Hardy-Weinberg equilibrium was tested by using the Pearson Chi-square (X2) test...

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Find And Correct II

Ngày tải lên : 27/06/2013, 11:46

... because he was a patriotic man, and he had been widely known A B C to be one of the greatest leader in the world D 35 He isn't driving to the conference in March, and neither Ms Thoa is A B C D ... went fishing after he has finished with the conferences A B C D 26 Peter and Tom plays tennis every afternoon with Mary and me A B C D 27 There were a time when I used to swim five laps every ... much does the car cost because he is going to buy it anyway A B C D 45 Mary and her sister studied biology last year, and so does Jean A B C D 46 Peter had already saw that musical before he read...

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exercise: pronunciation and word form

Ngày tải lên : 25/08/2013, 09:10

... commit 30.a justice b admit c adopt d improve 40.a ethnic b enjoy c legal d measure 31.a comprise b sandy c circle d northern @ VOCABULARY: WORD FORM He has been very interested in - - A biology ... for what you have done A responsible b responsibility c responsibly d irresponsible These quick and easy - - can be effective in the short term A solve b solvable c solutions d solvability He ... twins, they are seldom in - - A agree b agreeable c agreement d agreeably 11 The more - - and positive you look, the better you will feel A confident b confide c confidence d confidently...

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Tài liệu Chapter 6: Force and Motion II docx

Ngày tải lên : 13/12/2013, 05:15

... the crate does not move We push harder (frame c) and harder (frame d) and the crate still does not move Finally we push with all our strength and the crate moves (frame e) The free body diagrams ... frictional force As we increase F , f s also increases and the crate remains at rest When F reaches a certain limit the crate "breaks away" and accelerates to the left Once the crate starts moving ... Its magnitude is constant and is given by the equation: f k = µk FN µk is known as the coefficient of kinetic friction We note that: f k < f s ,max Note 1: The static and kinetic friction acts...

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Tài liệu Frontiers in Number Theory, Physics, and Geometry II docx

Ngày tải lên : 12/02/2014, 16:20

... theory, and Random matrices, with lectures by E Bogomolny on Quantum and arithmetical chaos, J Conrey on L-functions and random matrix theory, J.-C Yoccoz on Interval exchange maps, and A Zorich ... Herbert Gangl, Alexander B Goncharov and Andrey Levin on “Multiple logarithms, XII Preface algebraic cycles and trees” This work has been extended to multiple polylogarithms and to the world of ... 231 Universality and Randomness for the Graphs and Metric Spaces A M Vershik 245 XXVIII Contents Part II Zeta functions From Physics...

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Tài liệu Báo cáo khoa học: P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity pptx

Ngày tải lên : 14/02/2014, 21:20

... structure [19], and NMR spectroscopic data of p25a homologs from mice, Caenorhabditis elegans and humans [20–22] demonTable Determination of Vmax and Km for DAT, NET and SERT in the presence and absence ... between a-syn and DAT [10], but we were unable to co-immunoprecipitate p25a and DAT (data not shown) A series of protocols and antibodies were tested for co-immunoprecipitating p25a with DAT and DAT ... central core and unfolded N- and C-terminal extensions of 45 and 70 amino acid residues, respectively We constructed two deletion mutants: p25aDN, which lacked N-terminal residues 3–43, and p25aDC,...

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Tài liệu Báo cáo khoa học: Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo pptx

Ngày tải lên : 16/02/2014, 09:20

... family, and is also called GSTS1 [17] On the other hand, L-PGDS has been puriﬁed from rat brain [18], and is expressed in brain, heart, and male genital organs, as well as in adipocytes and omental ... the liver and WAT Parafﬁn sections of liver and WAT from WT and TG mice (S55) were stained with antibody against human H-PGDS Bars: 100 lm (D) PGDS activity in liver of WT and S41, S55 and S66 ... triglyceride, and glucose Blood was collected from the abdominal aorta Triglyceride and glucose levels were determined by using Triglyceride Test Wako (Wako Pure Chemical, Osaka, Japan) and Antsense II...

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Exercise, Health and Mental Health Emerging relationships docx

Ngày tải lên : 06/03/2014, 02:20

... Position Stand: exercise and physical activity for older adults Medicine and Science in Sports and exercise, 30, 992–1008 Paganini-Hill, A and Henderson, V W (1994) Estrogen deficiency and risk ... exercise on urges to smoke and withdrawal symptoms 9.1 Epidemiological studies examining exercise and sleep 9.2 Acute exercise and sleep studies 9.3 Chronic exercise and sleep studies 10.1 Research ... Professor of Exercise and Sport Psychology Loughborough University Leicestershire, UK xvii Foreword Exercise psychology is the study of brain and behavior in physical activity and exercise settings...

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Báo cáo khoa học: Modulation of IMPDH2, survivin, topoisomerase I and vimentin increases sensitivity to methotrexate in HT29 human colon cancer cells docx

Ngày tải lên : 07/03/2014, 16:20

... IMPDH type II is signiﬁcantly up-regulated in malignant cells [21,22] Benzamide riboside, tiazofurine and mycophenolic acid are potent inhibitors of this enzymic activity and phase II ⁄ III clinical ... to contain cDNAs related to proliferation and cancer Selected genes were validated by quantitative RT-PCR and their involvement in MTX -sensitivity was tested in functional analyses Some genes ... II trials, inhibits at least four enzymes involved in folate metabolism and purine and pyrimidine synthesis: thymidylate synthase, DHFR, glycinamide ribonucleotide formyltransferase (GARFT) and...

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Báo cáo Y học: Characteristics of binding of insulin-like growth factor (IGF)-I and IGF-II analogues to the type 1 IGF receptor determined by BIAcore analysis pptx

Ngày tải lên : 08/03/2014, 22:20

... effects, and by allowing 300 s for association and 900 s for dissociation In the case of IGF-I and related analogues, the concentrations used were 12.5, 25, 50, 100, and 200 nM, and for IGF -II and ... Time (s) Fig BIAcore analysis of IGF -II and IGF -II analogue binding to highanity recombinant IGF1R Binding of IGF -II (A), des-(1±6)-IGF -II (B) and Arg6-IGF -II (C) to rhIGF1R measured by BIAcore ... (4.45 nM) and IGF -II (17.8 nM) for the rhIGF1R (Figs 1A and 2A, Table 1) Substitution of Glu at position to Arg (Arg6-IGF -II) or deletion of the ®rst six amino acids of IGF -II (des-(1±6)-IGF -II) ,...

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Báo cáo khoa học: A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme docx

Ngày tải lên : 16/03/2014, 04:20

... in pGEMT and sequenced The plasmids generated were digested with ApaI and HindIII, taking advantage of the presence of the ApaI restriction site in the pGEMT polylinker and the HindIII site at ... H128P, PigE17DCPT1B and HumanD17ECPT1B, and from to 500 lm for D18PigCPT1B and D28PigCPT1B) The assay was performed at mm carnitine as standard To analyze PigE17DCPT1B and HumanD17ECPT1B mutants, ... PigE17D–pHW010, and HumanD17E–pHW010 These constructs were linearized in the GAPDH gene promoter by digestion with AvrII (constructs P50H, P128H and PigE17D) or BspMI (constructs H50P, H128P and HumanD17E),...

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Báo cáo khoa học: Apolipoproteins A-I and A-II are potentially important effectors of innate immunity in the teleost ﬁsh Cyprinus carpio pot

Ngày tải lên : 16/03/2014, 18:20

... 5-bromo-4-chloroindolyl phosphate and 0.33 mgÆmL)1 nitroblue tetrazolium protein bands on SDS/PAGE (lane 1), that correspond to apoA-I and A -II Delipidation of the concentrated HDL fractions and separation on ... peaks and contained isolated apoA-I and apoA -II, respectively (Fig 1, insert, lanes and 3) The identity of both apolipoproteins was demonstrated not only by their expected molecular mass (27.5 and ... indicate the migration of carp apoA-I (27.5 kDa) and A -II (12.5), respectively Table Bacteriostatic and bactericidal activities of carp apoA-I and A -II Each value in the table represents the mean...

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Science and Golf II PROCEEDINGS OF THE 1994 WORLD SCIENTIFIC CONGRESS OF GOLF docx

Ngày tải lên : 18/03/2014, 01:21

... Golf St Andrews, Scotland 4–8th July 1994 Held at the University of St Andrews and approved and grant-aided by the United States Golf Association and the Royal and Ancient Golf Club of St Andrews ... H.Zaitsu and T.Meshizuka 54 Spine and hip motion analysis during the golf swing 59 viii M.McTeigue, S.R.Lamb, R.Mottram and F.Pirozzolo Centrifugal force and the planar golf swing B.Lowe and I.H.Fairweather ... involving a low handicap player and a high handicap player In A.J.Cochran (ED.), Science and Golf: Proceedings of the First World Scientific Congress of Golf , University of St Andrews, Scotland London:...

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synthesis and high gas sensitivity of tin oxide nanotubes

Ngày tải lên : 20/03/2014, 13:08

... 4.7 ml ethanol and 0.3 ml HCl were mixed together and aged for 24 h, during which time the colour of the solution changed from white to pale yellow and ﬁnally forming a transparent and highly viscous ... form a solution; (ii) the AAO templates were impregnated by vacuum suction The solution was forced to pass through the pores of the template and adhere on the pore walls; (iii) the impregnated ... chemistry in energy storage and conversion, and development of chemical and biological sensors J.S Park received his Master degree in Materials Engineering in 2005 from Andong National University,...

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Báo cáo khoa học: A comparative study of type I and type II tryparedoxin peroxidases in Leishmania major pot

Ngày tải lên : 23/03/2014, 07:20

... were separated by SDS PAGE and stained with Coomassie Brilliant Blue: lanes and 2, TDPX1 wild-type; lanes and 4, TDPX1 Cys35Ala; lanes and 6, TDPX1 Cys83Ala; lanes and 8, TryP1 wild-type Odd ... Comparison between LmTDPX1 and LmTryP1 revealed some interesting similarities and differences Both enzymes obey saturable ping-pong kinetics with similar kcat ($ 15 and s)1) and Km ($ and lm) values for ... 30 column (Amersham) and 50 mm Hepes-NaOH pH 7.4 Gel Filtration Standard (Bio-Rad Laboratories, Hercules, CA) was used as calibration standards TryP1 and TryX were expressed and puried on a Ni-NTA...

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Báo cáo sinh học: "Enhanced presentation of MHC class Ia, Ib and class II-restricted peptides encapsulated in biodegradable nanoparticles: a promising strategy for tumor immunotherapy" docx

Ngày tải lên : 18/06/2014, 19:20

... analysis and manuscript preparation DM participated in nanoparticle characterization, DC loading and data analysis VK participated in data analysis and supervised studies related to murine class II and ... peptides to human DC, and the development of nanoparticles incorporating MHC class II and non-classical MHC class I, Qa-1-binding peptides that are able to stimulate helper CD4+ and cytotoxic CD8aa+TCRab+ ... (Waters, Milford, MA) Specifically, the peptides and nanoparticles were separated and identified using ultraviolet (UV) detection and known standards, at a wavelength of 280nm (attenuation 0.002...

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báo cáo hóa học:" Enhanced presentation of MHC class Ia, Ib and class II-restricted peptides encapsulated in biodegradable nanoparticles: a promising strategy for tumor immunotherapy" doc

Ngày tải lên : 20/06/2014, 03:20

... analysis and manuscript preparation DM participated in nanoparticle characterization, DC loading and data analysis VK participated in data analysis and supervised studies related to murine class II and ... peptides to human DC, and the development of nanoparticles incorporating MHC class II and non-classical MHC class I, Qa-1-binding peptides that are able to stimulate helper CD4+ and cytotoxic CD8aa+TCRab+ ... (Waters, Milford, MA) Specifically, the peptides and nanoparticles were separated and identified using ultraviolet (UV) detection and known standards, at a wavelength of 280nm (attenuation 0.002...

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