... it was the age of foolishness,
it was the epoch of belief, it was the epoch of incredulity,
it was the season of Light, it was the season of Darkness,
it was the spring of hope, it was the winter ... the hoofs of
the horse to the hat ofthe man.
"Guard!" said the passenger, in a tone of quiet business confidence.
The watchful guard, with his right hand at the stock of his ... the side ofthe
mail, as the rest ofthe passengers did; not because they had the
least relish for walking exercise, under the circumstances, but
because the hill, and the harness, and the mud,...
... yields the claim in (2.80). This completes the proof of
Lemma 6.
This completes the proof of Proposition 4 and hence of Theorem 1.
3. Proof of Theorem 2
In this section we indicate how the arguments ... second
term on the right-hand side ofthe analogue of (2.93).
4. Proof of Theorem 3
In Sections 4–6 we prove Theorems 3–5. The proof follows the same line
of reasoning as in [3, Đ5], but there are ... and
generalization ofthe proof of Proposition 3 in [3]. We outline the main steps,
while skipping the details.
Step 1. One ofthe basic ingredients in the proof in [3] is to approximate the
volume ofthe Wiener...
... the
beginning ofthe twentieth century there was but little night to speak of,
save in the sense of a division of time. The date ofthe paper which con-
tained the account ofthe tragedy on the Russian ... ran across the end at which the arm-racks were, and on
this Arnold laid the case containing the model, he standing on one side
of the table, and the members ofthe Circle on the other, watching ... to banish the emotion that he felt—
"Bravo, brother! Henceforth you shall be known to the Brotherhood as
the Master ofthe Air, for truly you have been the first among the sons of
men to...
... numbers over the diagrams indicate the position ofthe corresponding nucleotides relative to the translation start site, and the numbers
in parentheses below the diagram show the position ofthe corresponding ... of which the 3Â 380 bp were identical to
exons 13 from the 5Â-end ofthe reverse primer
DN+231 to the 5Â-end ofthe region where the
sequence of exon 1 reported previously [15] matched
with the ... generation oftwo kinds of gene transcript.
However, only the sequences ofthe 5Â-UTR are differ-
ent between them, because these transcripts share all
the other exons, exons 2–9, which contain the...
... from the top side ofthe drywall (this is the side
that has the lighter color of paper). To do this, spray the surface with water
until the paper peels away easily. The wetter the drywall, the ... Relief Sculpture in Two Parts
Sculpture Art Lesson
Vocabulary
aesthetic The science ofthe “beautiful” in a work of art. The aesthetic appeal
of a work of art is defined by the visual. Social, ... composition. the mathematical relationship ofthe parts to
each other and to the whole. For example, the relation ofthe head
to the body, etc.
shape Geometric shapes look as though they were made...
... essential for the binding of CP12. The
presence of this region at the interface of GAPDH and
CP12 could also explain the kinetic changes o bserved for the
binding ofthe substrate when the wild-type ... all mutant
GAPDHs indicate no changes ofthe global structure of the
mutants.
To test wh ether the interactions of these mutants with the
other partners o f the GAPDH–CP12–PRK complex were
impaired, ... Comparison of the
kinetics of these mutants with those ofthe wild-type
recombinant GAPDH shows that the beh aviour of R197A
mutant is not affected b y the m utation, suggesting that the
active...
... interpret the kinetic data. A comparison ofthetwo structures
and the experimental data suggested that the differences in the specificity
of thetwo enzymes may be mainly due to the variation in their ... underscoring the importance of
the interactions between the Tyr OH and the side
chains of Asn174 and Asp148 in TEV protease
(Fig. 4A). The importance of these interactions is fur-
ther supported by the ... effects
of the mutations. Hence, the results are consistent with
the predicted role for these residues (based on crystal
structure) in the interaction with substrate. The loss of
activity of the...
... facts ofthe case completely refute the vulgar notion, put
forth by the enemies ofthe Reformation, that Luther commenced the work ofthe Reformation for the sake of
enabling himself and other ... wall of steel. At the approach of the
peasants, thecities that were unable to resist them opened their gates and joined them. Wherever they
appeared they pulled down the images and broke the ... to the principles ofthe Gospel. The most notorious of these was Thomas Munzer, pastor of
Alstadt, in Thuringia; another was John Muller, of Bulgenbach, in the Black Forest, the inhabitants of...
... dictated the concluding part of the
lecture ofthe commanding officer, he made no further observation, and both in silence pursued the remainder
of their short route to the bastion.
Many ofthe men, ... dropped the incised portion ofthe hide, and was again using his knife; the Virginian,
stooping slightly at the off-side ofthe window, ascertained that the feet ofthe former were resting on one of
the ... above them, and then a prolonged yell, which was answered by others from the front of
the house, echoed through the surrounding forests. Even amid the horrid discord, the quick ear of the
Virginian,...
... evenings at the California Theatre, were announced. All of these
concerts were of a classical character, the first ofthe kind ever given in the State and to bring them out
properly the best talent ... enter the
Conservatory. There were only nine places and there were seventy-six applicants and every one of them boys.
When they grew up they could play in the theatres. That was the aim of their ... of it they were ready for a change of residence.
They could not afford the rent ofthe rooms on the Rue St. Nicholas d'Antin, and they found cheaper quarters
in a flat just under the roof...
... rates of transcription initiation and elongation
between thetwo genes, and ⁄ or from variation in the
rates of degradation ofthetwo messages. To test the
first hypothesis, the gene copy number of ... [27], the lack of a transcriptional
response ofthe Hsp70 genes to thermal shock [28], and
modifications in the primary structures ofthe a- and
b-tubulin [29–31] and ofthe proteins that form the ... or the egress of GDP and P
i
, which may in
turn control the assembly and stability of new basal
bodies [25]. The most striking of these is the G72R
substitution of c-T2 near the entrance to the
AB
Fig....
... to
40% ofthe parent enzyme activity.
In a more in-depth evaluation ofthe function ofthe three
serine mutants, the kinetic properties ofthe mutant enzymes
were compared to those ofthe parent ... ends of
the putative b-strands, lining the face ofthe predicted active
site cleft [15]. These proposed structural features ofthe GT1
motif in GalNAc-T1 are similar to the UBD, raising the
possibility ... scanning ofthe bands on the blotting membrane.
The enzymatic activities were correlated with the concen-
tration of recombinant proteins in the media. This was done
to evaluate the effects of the...
... afterwards, the 31st of March, when
they entered the broad mouth ofthe river and dropped anchor off the town of Brill. It was late in the evening
when they arrived. In the morning an officer came off ... deeply sullied the cause for which he fought.
Upon the day after the capture ofthe city, the Good Venture went into the port. The inhabitants, as soon as
they learned that the beggars ofthe sea respected ... and commenced the long war that was to end only with the establishment ofthe Free Republic
of the Netherlands. No harm was done to such ofthe inhabitants ofthe town as remained. The conquerors
established...
... From the middle ofthe gulf the point ofthe land it-
self is not visible at all; but the shoulder of a steep hill at the
back can be made out faintly like a shadow on the sky.
On the other ... birth ofthe Occidental Republic,
she is the only one who has kept in my memory the aspect
of continued life. Antonia the Aristocrat and Nostromo the
Man ofthe People are the artisans ofthe ... S
countenance by their presence the enterprise in which the
capital of their countries was engaged. e only lady of that
company was Mrs. Gould, the wife of Don Carlos, the ad-
ministrator ofthe San...
... among the special favorites ofthe king. Many ofthe girls were assigned to the queen and
royal princesses, others to the wives ofthe priests and generals who formed the council ofthe king. The ... spread the news
of the defeat ofthe army. The cries of women filled the air; some in their grief and terror ran wildly here and
there; some sat at their doors with their faces hidden by their ... ofthe causeway cost the Egyptians heavily, for while they were exposed to
the arrows ofthe Rebu archers these were now beyond the range ofthe Egyptians on the opposite crest. But at
last the...