... domains of HIP -1 The ANTH ⁄ ENTH domain (38 16 0), coiled-coil domain (3 71 610 ), and talin-like domain ( 814 11 12) were predicted with the SMART tool (http://smart.embl-heidelberg.de/) Binding ... apoptosis following the intrinsic pathway [17 , 21] The pseudodeath effector domain (pDED) of HIP -1 (Fig 1) alone is able to induce apoptosis; Phe398 of HIP -1 (within the pDED) is critical for increased ... explanation forthe increased caspase -1 expression in HD In HD, owing to weaker interactions of HIP -1 with the mutated Htt, the free HIP -1 pool might increase, and this in turn would lead to the formation...
... chromosome 11 q13 loci, encoding a 67 kD nuclear protein of 610 amino acids, called menin [24] Various types of mutations scattered throughout the 10 coding exons of the MEN1 gene inactivate the MEN1 gene ... neuroendocrine tumor, somatostatin receptor imaging with Indium 11 1 (OctreoScan®) disclosing radionuclide material uptake inthe left upper quadrant of the abdominal cavity at some point between the ... promoters by binding to TRE consensus Menin-JunD interaction involves the N-terminus (amino acids 1- 40) and midregion (amino acids 323-428) of Menin and requires the N-terminus of JunD (amino acids...
... rice lines for atp9, atpa and atp6 genes Southern blot analysis of the APMS-6A WA sterile line (lanes: 1, 3, 5, 7, 9) along with the corresponding maintainer APMS-6B (lanes: 11 , 12 , 13 , 14 , 15 ) ... fertile line Interestingly, however, inthe clone with the largest insert (6A25 -11 ) editing was absent Sequence analysis also indicated the insert contained a portion of the 5’ UTR region of the orfB ... detected in 0.7 kb orfB gene transcripts of the fertile lines It was therefore inferred that the clone contained an insert originating from the long 1.1 kb transcript of the orfB gene Furthermore,...
... Specific binding of a basic peptide from HIV -1 Rev Embo J 19 92, 11 (3) :11 19 -11 29 Tiley LS, Malim MH, Tewary HK, Stockley PG, Cullen BR: Identification of a high-affinity RNA-binding site forthe human ... expression from the Rev dependent pDM138 reporters This indicated that the NOS-M4 mutant binds to the IIB RNA sequences by the Rev basic domain leaving the Rex domain free for other interactions The previous ... corresponding to the basic domain of Rev inhibited thein vitro splicing of RRE containing mRNAs underscores the functional importance of this region [39,40] These results therefore support the suggestion...
... REVIEW 1.1 Definition of “Discipline” 1. 2 Types of Classroom Disciplines 1. 3 Definitions of “Motivation” 1. 4 Factors affecting discipline and motivation in a language classroom 1. 4 .1 The teachers’ ... Interviews 2.4.2 .1 Some specific disruptive behaviors 2.4.2.2 Reasons for indiscipline 2.4.2.3 Solutions to disruptive behaviors Page i ii iii iv 1 2 3 11 11 13 13 15 17 19 21 22 22 22 23 23 ... background inthe 11 th form participated inthe survey to help achieve the objectivity, reliability and validity of the survey Since the survey was also carried out inthe form of interviews,...
... director in a specific title to other material they may be interested inThe buttons inthe results panel can be pointed at (clicked on) in order to view the details inthe left panel for that ... Of the remaining 66% of inputs ( 216 6) which were within the functionality of the system, 68% were in grammar On the within functionality portion of the data, the word accuracy was 62%, and on in ... half of the subjects used the tablet and then the remote control and the other half used the remote Here we report results forthe wireless microphone only Analysis of the other microphone conditions...
... antibiotic (amoxycillin tablet—250 mg): Age months up to 12 months 1 tablet Age 12 months up to years 1 tablets For any sick child who can drink, advise to give fluids and continue feeding Advise to ... been taken by the World Health Organization to verify the information contained in this publication However, the published material is being distributed without warranty of any kind, either expressed ... expressed or implied The responsibility forthe interpretation and use of the material lies with the reader In no event shall the World Health Organization be liable for damages arising from its use...
... will find it inthe Latin -1 character set after the letter ö, using Insert > Symbol … in Word Inthe Mathematical Operators character set, using Insert > Symbol … in Word Key code for Windows: ... Guangzhou (Canton) Nanjing (Nanking) Xinjiang (Sinkiang) The spelling of Shanghai remains thesame Add the old form in parentheses if you think it necessary 32/88 May 2 013 English Style Guide ... points, either by incorporating the final phrase inthe introductory sentence or by starting a new sentence When translating lists, always use thesame type of numbering as inthe original, e.g Arabic...
... R 110 G F 112 R R 114 A Y 116 D WT 25.4 25.5 25.4 25.5 25.5 29–443 29 15 0 29–500 29–443 29–669 17 20 17 26 COS -1 cells R 110 G F 112 R R 114 A Y 116 D WT 20.7 20.8 20.7 20.8 20.8 14 .2–443 14 .2 15 0 14 .2–500 14 .2–443 ... b-parallel b-turn Random coil 20.3 18 .0 10 .2 16 .7 34.8 20.2 18 .2 10 .2 16 .6 34.8 25.7 12 .9 9.7 16 .9 34.9 19 .3 20.5 10 .1 16.9 33.3 17 .7 21. 6 10 .3 16 .5 34.0 17 .7 23.0 10 .0 16 .8 32.5 Discussion Fig Secondary ... and their b-strand elements inthe a-crystallin domain, the amino acid substitution F 112 R introduces two changes at the dimer–dimer interface Although Y 116 and R 114 are in b-strand 7, neither...
... molecular extinction coefficients corresponding to maximal reduction of the various electron donors: 0.069 lM )1 cm )1 for dithionite, 0.059 lM )1 cm )1 for menadiol and 0.0 31 lM )1 cm )1 for duroquinol These ... ubiquinol as electron donor according to conditions of growth 10 11 12 13 14 Acknowledgements We are indebted to Dr F Blasco for his help inthe construction of mutant strains, to Dr G Giordano for ... determine binding sites of quinols, inhibition by HOQNO (a structural analogue of menaquinone), did not allow them to see the binding site of ubiquinol because HOQNO is not an inhibitor for the...
... disease rather than train them inthe daily management* of their condition Therapeutic patient education* is designed therefore to train patients inthe skills* of self-managing or adapting treatment ... inform them about the nature and significance of the subject Two levels of training in therapeutic patient education* are in use: basic and postbasic Basic training concerns the practice of therapeutic ... objective health needs* Training should be objective-based and the objectives* of two types: therapeutic, forthe patients, and learning*, forthe educators It includes training inthe evaluation* of...
... : : : : : : : : : : : : : 10 6 10 6 11 1 11 3 11 6 12 4 13 4 13 5 13 6 14 2 14 4 14 5 14 7 14 9 15 2 15 3 15 6 15 7 15 9 16 2 16 5 Supporting Indices inthe POSTGRES Storage System 5 .1 Introduction : : : : : : : ... RETAIN to determine if thesame failure has occurred at another site If so, information stored in RETAIN identifies a tape containing a fix forthe problem If the problem has never occurred before, ... is inthe section following the description of the error model The final section below outlines the remainder of the dissertation 1. 2 A Model of Software Errors Incorporating Error Propagation The...
... setting Involvement of the National TB and HIV Program staff inthe development phase facilitated the use of the training materials by the National Program inthe roll-out of TB/HIV training for ... developing the training AVR conceived of the study, participated in developing the training, coordinated the study with FB and helped to draft the manuscript All authors read and approved the final ... of pre- and post-training assessments and observations made during the training guided the revision of the initial training manual Topics that raised confusion or remained insufficiently understood...
... previous report [15 ] indicating that WNV replicates locally in draining lymph nodes in mice inoculated subcutaneously, then inthe spleen and in multiple sites inthe CNS, although the sites of extraneural ... limited in its scope, the results indicate that WNV strain IS-98-ST1 is suitable as viral model for West Nile encephalitis inthe Old World The Israeli strain IS-98-ST1 that caused the epizootic in ... Variations in biological features of West Nile viruses Ann N Y Acad Sci 20 01, 9 51: 195-206 Page of (page number not for citation purposes) Virology Journal 2004, 1: 9 13 14 15 16 17 18 19 http://www.virologyj.com/content /1/ 1/9...