... chronic gastritis and ulcer(normal group), 50 with IM including adenoma (high risk group), 40 with EGC (EGC group), 45 with AGC with- out distant metastasis (AGC group), and 42 with meta-static ... gastriccarcinogenesis. Serum HMGB1 levels were significantly associatedwith depth of invasion, lymphnode metastasis, tumor size, and poor prognosis (p < 0.05). However, HMGB1 levels were not associated with ... it is still a seri-ous health problem [18]. The prognosis of advanced gas-tric cancer (AGC) with extensive node invasion andmetastasis remains poor while early gastric cancer (EGC) is associated...
... when compared with the other two groups. Also, this high cholesterol correlated positively with the tHcy level. This high cholesterol might be attributed to increase in weight gain with age, lack ... heart diseases and the high plasma tHcy [14, 39, 40]. This finding might explain the higher degree of CIT in Gp2 and Gp3 compared to Gp1 (young healthy controls). It is hypothesized that the high ... Coagul Fibrinolysis. 2002;13(3):271-5. 53. Klerk M, Verhoef P, Clarke R, Blom HJ, Kok FJ, Schouten EG. MTHFR 677C >T polymorphism and risk of coronary heart disease: a meta-analysis. JAMA. 2002;288(16):2023-31....
... Multivariate analysis of factors associatedwith ICU LOS Table 2 demonstrates that hypoglycemia—minimum BG < 50 mg/dL as well as minimum BG 50–69 mg/dL is independently associatedwith prolonged ... of the patients with hypoglycemia in the NL cohort had an episode within the first 48 hours of ICU admission. Figure 5 displays the strong association between the number of episodes of hypoglycemia ... episode of hypoglycemia (BG < 70 mg/dL) ranged from 17.8% (GL-C) to 64.9% (NL-S) Comparison of patients with and without hypoglycemia Table 1 demonstrates differences between patients with...
... the two. Our study estab-lished obesity as a risk factor for new diagnosis of asthma,the risk increasing with higher levels of obesity. Thesefindings should be the basis for future controlledinvestigations ... 8,960 Britishadults were higher in overweight women.9ORs were 1.51in those with a BMI of 25.0 to 29.9 kg/m2and 1.84 in those with a BMI of at least 30.0 kg/m2compared with those with a BMI ... a 25 kg weight gain was associated with a 2.5-fold increase in the risk for diagnosisof asthma compared with no significant weight gain.11In across-sectional analysis of 18,000 children aged...
... medialis at the patellofemoral joint is alsosupported by electromyography studies, which demonstratedthat delayed activation of vastus medialis relative to vastus lat-eralis isassociatedwith ... study is unknown. Thus, the aim ofthis study was to examine the determinants of vastus medialisand lateralis cross-sectional areas and whether vastus media-lis cross-sectional area isassociated ... results in a pain-free population without clinical knee oste-oarthritis suggest that increased cross-sectional area of vas-tus medialis, which isassociatedwith participation in vigorousphysical...
... Research Divisions. We also thank Dr Olle Olerup for providing us with HLA typing kits, Miss Diab Diab for technical assistance with HLA typ-ing, and Mr Ben de Jong for technical assistance with serum ... Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's ... confidence interval 0.9–4.2). This study showed thatthe presence of anti-CCP antibodies together with SE genecarriage isassociatedwith a very high relative risk for futuredevelopment of RA.Keywords:...
... univariateanalysis (P > 0.05) and Cox's multivariate analysis.Table 1: Distribution of 50 patients with cutaneous melanoma in terms of primary diagnosis and location of tumor and first metastasisPrimary ... metastases and one for disease in the axilla, all with palliative intent.ImmunohistochemistrySections of paraffin-embedded metastasis specimens wereinitially stained with hematoxylin-eosin ... family in the study ofCaenorhabditis elegans, opened new perspectives for thestudy of tissue morphogenesis and oncogenesis [9,11,18].Inhibition of apoptosis can occur in any phase of the cellcycle,...
... -168A>G polymorphism has convinc-ingly been associatedwith MHC2TA gene expression, it is unclear whether the polymorphism itself is functional orwhether it is in linkage disequilibrium with one or ... Revisions requested: 6 Apr 2006 Revisions received: 8 May 2006 Accepted: 17 May 2006 Published: 15 Jun 2006Arthritis Research & Therapy 2006, 8:R97 (doi:10.1186/ar1974)This article is online ... purposes)Vol 8 No 4Research articleThe MHC2TA -168A>G gene polymorphism is not associatedwith rheumatoid arthritis in Austrian patientsBabak Yazdani-Biuki1, Kerstin Brickmann1, Klaus...
... deviation) disease duration in comparison with SLEpatients who never had a major infection. Furthermore, the per-centage of SLE patients with a previous SLE glomerulonephri-tis was significantly higher ... Comparison of risk factors for vascular disease inthe carotid artery and aorta in women with systemic lupuserythematosus. Arthritis Rheum 2004, 50:151-159.35. Vitali C, Bencivelli W, Isenberg ... analysis.As a consequence of the low number of opportunistic infec-tions since lupus onset in our patients, a further analysis of var-iables associatedwith the occurrence of opportunisticinfections...
... IFIH1 is a highly IFNβ-inducible protein that is thought important in mediating IFNβeffects such as growth inhibition and apoptosis [23]. Immuno-histochemical analysis has shown IFNβ to be highly ... Revisions requested: 27 Feb 2007 Revisions received: 16 Apr 2007 Accepted: 18 Apr 2007 Published: 18 Apr 2007Arthritis Research & Therapy 2007, 9:R40 (doi:10.1186/ar2179)This article is ... explainedby the reported link with preceding viral infections, as thisgene is thought to contribute to the apoptosis of virallyinfected cells [19]. Viral RNA is sensed via a helicase domainresulting...
... LLI.The most probable explanation for this finding is that, despiteopinion found in textbooks, no association actually exists. Thisreasoning is consistent with the near absence of data support-ing ... 11cases with ipsilateral longer leg, and 17 cases with bilateralGTPS) and in 163 subjects without GTPS; therefore, 13.7%of subjects with GTPS had a LLI compared with 14.1% ofthose without ... 2007 Revisions received: 12 Apr 2008 Accepted: 29 May 2008 Published: 29 May 2008Arthritis Research & Therapy 2008, 10:R62 (doi:10.1186/ar2433)This article is online at: http://arthritis-research.com/content/10/3/R62â...
... inmultivariate analysis. BMI was positively associatedwith vas-tus medialis cross-sectional area in multivariate analysis, with a similar trend observed with vastus lateralis. Participation invigorous ... medialis at the patellofemoral joint is alsosupported by electromyography studies, which demonstratedthat delayed activation of vastus medialis relative to vastus lat-eralis isassociatedwith ... that age was nega-tively associatedwith vastus medialis and with vastus lateraliscross-sectional area. Women had significantly smaller vastusmedialis and vastus lateralis cross-sectional area...
... competing interests.AcknowledgementsThis work is supported by an Arthritis Research Campaign Clinical Fel-lowship grant (grant number 18848 to TET) and an Arthritis ResearchCampaign infrastructure ... Foundation Trust, Department ofRheumatology). HJ is supported by an Arthritis Research CampaignEducational Research Fellowship Grant (grant number 17883). VFP is supported by a PhD scholarship from the ... associates with a reduced prevalence of the meta-bolic syndrome in rheumatoid arthritis patients over the ageof 60: more than just an anti-inflammatory effect? A cross-sectional study. Arthritis Res...
... antiretrovi rals is often accompanied with a gradual loss of viral fitness,indicating that mutations withhigh fitness costs are lessable to persist in the absence of drug pressure [1].There ... 3.6HIVGradePhenotypeResistantIntermediateSensitiveResistantIntermediateSensitiveFigure 1 Resensitizing effects of the L76V mutation are visible in phenotype results: Phenotypic resistance analysis before ... selective pressure of drug therapy may also lead to shifts in the quasispe-cies distribution and fitness of those mutants with decreased sensitivity to the respective antiretrovirals[11,12]. This...