subtraction rna amplification and cdna synthesis

Báo cáo y học: "The CRIT framework for identifying cross patterns in systems biology and application to chemogenomics" ppt

Ngày tải lên : 09/08/2014, 22:24

... drugs labeled as high and low, and the denominator is simply the difference between the standard error for high and low Welch’s t-statistic was used to compute P values, and proteins with P < ... transcription factors and their associated targets in the yeast regulatory network, relationships between gene properties such as expression and binding status and breast cancer type, and finally using ... for both AR and ABsensitive proteins and in DNA binding for AR and hydrophilicity-sensitive proteins In addition, charge-sensitive proteins showed an enrichment in transferase activity and MlogP...

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Tài liệu Process purpose and target: docx

Ngày tải lên : 22/12/2013, 02:18

... Management Check on conformity No Process owner Yes Realization on paper HQU 01 - Chapterl 07 Internal communication Issued by Ing Berghofer Process owner Process owner Date Juli 2001 Version page...

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Tài liệu Báo cáo khoa học: Molecular characterization of Arabidopsis thaliana PUF proteins – binding speciﬁcity and target candidates doc

Ngày tải lên : 18/02/2014, 06:20

... human and mouse possess two; and Drosophila and Dyctiostelium have only one member [5] Recently, new studies have revealed the presence of ten, two and one homologs in Trypanosome, Plasmodium and ... elegans FBF recognize RNA that have the UGUR and AUA sequence separated by two nucleotides, whereas C elegans PUF-8, Drosophila and human Pumilio and yeast Puf3 recog- FEBS Journal 276 (2009) 5456–5470 ... including RNA processing, export, localization, degradation and translational regulation [57,58] Recent studies have shown that speciﬁc RNA- binding proteins associate with large and distinct mRNA populations,...

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Báo cáo khoa học: Nuclear localization of human spermine oxidase isoforms – possible implications in drug response and disease etiology pptx

Ngày tải lên : 07/03/2014, 05:20

... existence of SMO5 in human normal and tumor cell lines SMO5 cDNA was subcloned and sequenced, and active protein was produced, purified and assayed for kinetic properties and substrate specificities NCI-H157 ... for RT- and realtime PCR (B) Expression of SMO5 mRNA in human lung cells Total RNA was extracted from: (1) A549; (2) A549 + 10 lM BENSpm; (3) H157; or (4) Beas2B cells One lg of each RNA sample ... PAOh1 protein band (Fig 2C) SMO5 protein purification To further study and characterize the SMO5 protein, SMO5 cDNA was subcloned into the pET15b bacterial expression vector The 1984 bp cDNA (GenBank...

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Báo cáo khoa học: "Learning to Translate with Source and Target Syntax" pot

Ngày tải lên : 07/03/2014, 22:20

... bitexts, and one on two billion words of English These were smoothed using modiﬁed Kneser-Ney (Chen and Goodman, 1998) and stored using randomized data structures similar to those of Talbot and Brants ... source and target side, which reduces the number of eligible phrases Table shows an analysis of phrases extracted from human word-aligned and parsed data and automatically word-aligned and parsed ... similar to the expanded set recently used for Hiero (Chiang et al., 2009), but with bigram features (source and target word) instead of trigram features (source and target word and neighboring...

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ECONOMIC AND SOCIAL CONSEQUENCES OF DRUG ABUSE AND ILLICIT TRAFFICKING doc

Ngày tải lên : 08/03/2014, 06:20

... international trade in iron and steel and motor vehicles (2.8 per cent and 5.3 per cent respectively) and approximately the same size as the international trade in textiles (7.5 per cent), oil and ... Europe: Belgium, Denmark, Finland, France, Germany, Italy, Netherlands, Norway, Portugal, Spain, Sweden, Switzerland and the United Kingdom of Great Britain and Northern Ireland Sources: UNDCP country ... specific dates and magnitudes), cases of SARM increased by a factor of in Germany and Spain, and a factor of approximately in Austria, Belgium, Italy and Switzerland In France and the United...

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Báo cáo khoa học: "Bridging Morpho-Syntactic Gap between Source and Target Sentences for English-Korean Statistical Machine Translation" pot

Ngày tải lên : 17/03/2014, 02:20

... particle and an objective particle , and insert them after the corresponding dependents Eugene and guitar respectively on content-words, which can deteriorate the performance of candidate ... any English words, and can simply and easily be removed by referring to their POS information The unaligned words are case particles, ﬁnal endings, and auxiliary particles, and they call these ... 2005; Xia and McCord, 2004; Zwarts and Dras, 2007) Some reordering approaches have given signiﬁcant improvements in performance for translation from French to English (Xia and McCord, 2004) and from...

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Báo cáo khoa học: "Resolving Translation Ambiguity and Target Polysemy in Cross-Language Information Retrieval" potx

Ngày tải lên : 17/03/2014, 07:20

... and Polysemy Resolution Models In the recent works, Ballesteros and Croft (1998), and Bian and Chen (1998) employ dictionaries and co-occurrence statistics trained from target language documents ... these words be CW~, CW2, , and C W m Assume the corresponding English translations of C, CW~, CW2, , and CWm are E, EW,, E W , , and EWm, respectively EWe, EW2, , and EWm form an augmented translation ... work (Bian and Chen, 1998), which combines the dictionary-based and corpus-based approaches for CEIR A bilingual dictionary provides the translation equivalents of each query term, and the word...

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the effect of the hydrothermal treatment with aqueous naoh solution on the photocatalytic and photoelectrochemical propertiesof visible light-responsive TiO2thin ﬁlms

Ngày tải lên : 20/03/2014, 13:11

... patterns of Vis-TiO2/Ti and NaOH(X)-Vis-TiO2/Ti and (b) the expanded XRD patterns of (a) (2u = 5–158) Fig XPS spectra of the Ti 2p (right) and Na 1s (left) peaks of the Vis-TiO2/Ti and NaOH(X)-Vis-TiO2/Ti ... (Laforet Engineering, XD50D) and the evolved H2 and O2 were analyzed by a gas chromatograph (GC, G2800-T, Yanaco) with a thermal conductivity detector (TCD) Results and discussion Photoelectrochemical ... titanates such as A2Ti3O7 or A2Ti2O5 H2O, where A represents Na and/ or H [17] Fig shows the Ti 2p and Na 1s XPS spectra of the VisTiO2/Ti before and after hydrothermal treatment The intensity of the Ti...

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financial statement analysis Abbott Laboratories and Target

Ngày tải lên : 25/03/2014, 12:18

... 23.83% Property and equipment Land Buildings and improvements Fixtures and equipment Computer hardware and software Construction-inprogress Accumulated depreciation Property and equipment, net ... numerous countries and employs both internal and external tax professionals to minimize audit adjustment amounts where possible Changes in foreign reimbursement, political and economic stability ... building‘s useful life is 10 to 50 years and equipment is to 20 years They also noted internal controls and the external audit being completed by Deloitte and Touche out of Chicago Deloitte did...

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MASS SPECTROMETRY IN DRUG METABOLISM AND DISPOSITION docx

Ngày tải lên : 28/03/2014, 10:20

... hydroxylamines and oximes and secondary amines to N-hydroxy and nitrone products Aromatic amines and amides are not substrates Thioethers can be oxidized to sulfoxides; and thiols, thioamides, and thiocarbamates ... be used as a teaching and/ or reference tool to delineate and understand the “why” and “how” with regard to the many creative uses of mass spectrometry in drug metabolism and disposition studies ... Lee, and Guodong Chen Characterization of Impurities and Degradants Using Mass Spectrometry Mike S Lee and Mingshe Zhu Mass Spectrometry in Drug Metabolism and Disposition: Basic Principles and...

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Báo cáo khoa học: Role of the plasma membrane leaﬂets in drug uptake and multidrug resistance ppt

Ngày tải lên : 29/03/2014, 08:20

... Randles J & Brand JS (1975) Assay of picomole amounts of ATP, ADP, and AMP using the luciferase enzyme system Anal Biochem 69, 187–206 FEBS Journal 277 (2010) 1234–1244 ª 2010 The Authors Journal ... of TMA-DPH and the excitation spectrum of TMRM, FRET can occur, provided that the probe and the drug are sufﬁciently close FEBS Journal 277 (2010) 1234–1244 ª 2010 The Authors Journal compilation ... in the lipid core and is expected to be FEBS Journal 277 (2010) 1234–1244 ª 2010 The Authors Journal compilation ª 2010 FEBS H Katzir et al Cytoplasmic leaﬂet in drug uptake and resistance K562/ADR...

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For Medicare Advantage Plans, Medicare Advantage Prescription Drug Plans, Prescription Drug Plans, and 1876 Cost Plans ppt

Ngày tải lên : 29/03/2014, 23:20

... name(s) or brand(s) of the co-branding entity or entities on its marketing materials to signify a business arrangement Co-branding arrangements allow a plan sponsor and its co-branding partner(s) ... Drug Program’s (NCPDP’s) “Pharmacy and/ or Combination ID Card” standard This standard is based on the American National Standards Institute ANSI INCITS 284-1997 standard titled Identification Card ... Formulary and Utilization Management (UM) Requirements 81 110 - Reserved 83 120 - Marketing and Sales Oversight and Responsibilities 83 120.1 - Compliance with State Licensure and...

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Báo cáo khoa học: "Combining Source and Target Language Information for Name Tagging of Machine Translation Output" ppt

Ngày tải lên : 31/03/2014, 00:20

... previous token F4 and F5 are used to help resolve the type conflicts, and F6 and F7 to resolve boundary conflicts When there is a conflict, we need the confidence information from both ET and English ... and William J 2005 HMM Word and Phrase Alignment for Statistical Machine Translation Proc Human Language Technology Conference and Empirical Methods in Natural Language Processing Fei Huang and ... which addresses some of the tag conflict situations and gets additional gains Results from English NER and ET First, we analyzed the English NER and ET output to see the named entity distribution...

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fragment based drug discovery and x-ray crystallography

Ngày tải lên : 29/05/2014, 23:54

... Davies and Ian J Tickle Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening 61 Stephen Roughley, Lisa Wright, Paul Brough, Andrew Massey, and Roderick E Hubbard Combining NMR and ... Potent and Selective BACE-1 Inhibitors Daniel F Wyss, Yu-Sen Wang, Hugh L Eaton, Corey Strickland, Johannes H Voigt, Zhaoning Zhu, and Andrew W Stamford 83 Combining Biophysical Screening and X-Ray ... Marsh, Sandra Greive, and Marko Hyvonen Fragment Screening and HIV Therapeutics 181 Joseph D Bauman, Disha Patel, and Eddy Arnold Fragment-Based Approaches and Computer-Aided...

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báo cáo hóa học: " Simultaneous buried object detection and imaging technique utilizing fuzzy weighted background calculation and target energy moments on ground penetrating radar data" potx

Ngày tải lên : 21/06/2014, 00:20

... Defense and Security Symposium, Detection and Remediation Technologies for Mines and Mine like Targets, Orlando, USA (13-17 April 2009) DJ Daniels, P Curtis, O Lockwood, Classification of landmines ... Development of dual sensor hand-held detector, in SPIE Defense and Security Symposium, Detection and Remediation Technologies for Mines and Mine like Targets, Orlando, ABD, (5-9 April 2010) M ... 25 26 using GPR B-scan data, in SPIE Defense and Security Symposium, Detection and Remediation Technologies for Mines and Mine like Targets IX Orlando (2004), 905–912 TG Savelyev, LV Kampen,...

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Báo cáo hóa học: " Target estimation algorithm design using quantity data and target feature" pptx

Ngày tải lên : 21/06/2014, 03:20

... Lu and Lin EURASIP Journal on Advances in Signal Processing 2011, 2011:7 http://asp.eurasipjournals.com/content/2011/1/7 system is presented in ... Output Figure Image identification process (10) Lu and Lin EURASIP Journal on Advances in Signal Processing 2011, 2011:7 http://asp.eurasipjournals.com/content/2011/1/7 Where f(x,y) is the image ... measurement image; (Y (i,j) ), (i,j)th pixel of template Lu and Lin EURASIP Journal on Advances in Signal Processing 2011, 2011:7 http://asp.eurasipjournals.com/content/2011/1/7 image; X , average value...

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DRUG DISCOVERY AND DEVELOPMENT – PRESENT AND FUTURE pptx

Ngày tải lên : 27/06/2014, 17:20

... Polymorphism and the Concept of Prakriti in Ayurveda The Journal of Alternative and Complementary Medicine Vol.11,No., 2, 349-353, Drug Discovery and Ayurveda: Win-Win Relationship Between Contemporary and ... Safety Pharmacology and Drug Interaction Evidencebased Complementary and Alternative Medicine Vol.2011,No., 24 Drug Discovery and Development – Present and Future Sharma H , Chandola HM (2011) Prameha ... New Delhi: Department of AYUSH and CSIR, pp 1-30 2 Evolutionary Biology and Drug Development Pierre M Durand and Theresa L Coetzer University of the Witwatersrand and National Health Laboratory...

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Báo cáo khoa học: "SemiFDG-PET/CT imaging for staging and target volume delineation in conformal radiotherapy of anal carcinoma" potx

Ngày tải lên : 09/08/2014, 08:22

... (66.7%) cases and disease-free and overall survival (DFS and OS) rates were 66.7% and 77.8% respectively Acute and late toxicity higher than grade (RTOG/EORTC) was observed in 7/27 (25.9%) and 1/27 ... study and drafted the manuscript MEM, LT, CB and LD were involved in data collection and review EM, BC and MC worked on analysis of data EI and MB participated in the design of the study and contributed ... cm at the level of the primary tumor and included the uninvolved regional lymph nodal areas, i.e bilateral inguinal, external and internal iliac, perirectal, and presacral lymph nodes (Figure 1)...

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Báo cáo y học: " Injection drug use and patterns of highly active antiretroviral therapy use: an analysis of ALIVE, WIHS, and MACS cohort" ppt

Ngày tải lên : 10/08/2014, 05:20

... one NRTI and at least one PI and at least one NNRTI, 3) an abacavir- or tenofovir-containing regimen with at least NRTIs, 4) a regimen containing ritonavir and saquinavir and one NRTI, and no NNRTIs ... contributions to conception and design, acquisition of data, and analysis and interpretation of data; 2) have been involved in drafting the manuscript; and 3) have read and given approval of the ... pre-HAART markers (CD4 and HIV RNA) , prior antiretroviral therapy exposure, smoking, low income, and being unemployed In separate analyses, we examined the impact of current and former injection...

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