... Origins ofthe Bank of Canada I • The Bank was created by the Bank of Canada Act in 1934 and started operations in 1935 • Initially the Bank was a private institution but was nationalized in 1938, ... for the regulatory oversight ofthe national payments system, operated by the CPA • acts as the holder of deposit accounts ofthe federal government, the directly clearing members ofthe CPA, international ... exchange reserves held by the Exchange Fund Account ofthe Department of Finance • engages in international financial transactions, on behalf ofthe government, in order to influence exchange rates...
... RISK-TAKING BEHAVIOUR AND OWNERSHIP INTHEBANKING INDUSTRY: THE SPANISH EVIDENCE Abstract: This paper analyses the determinants of risk-taking inthe Spanish financial intermediaries ... However, the effect over risk of politicización ofthe decision making is not clearly defined (La Porta et al., 2002) In one hand, the interest of politicians in conserving the use ofthe savings ... diversity of interests in Savings banks' governance structure may cause a dissimilar pattern of risk-taking In particular, if any interest group within the board of SSB gains control over the institution,...
... documents the significant expansion ofthe financial system and, in particular, thebanking system inthe run-up to the financial crisis It assesses the impact ofthe financial crisis on the EU banking ... Similarly, the trading entity can engage in a broad range of activities The proposal addresses the core weaknesses inthebanking sector, while retaining the key benefits ofthe universal banking model ... with the objective of establishing a safe, stable and efficient banking system serving the needs of citizens, the EU economy and the internal market In evaluating the European banking sector, the...
... substrates: inthe first, a (small) sub population of enzyme binds directly the steroid inthe reactive conformation, with the remainder ofthe enzyme binding the unreactive conformation Rescue ofthe ... ofthe enzyme-steroid complex We conjectured that the reduced form ofthe enzyme might direct binding ofthe steroid inthe flipped conformation, thus facilitating catalysis Our structureofthe ... Moreover, in these inhibitor complexes the steroid is bound inthe active site in a similar manner to the binding of steroid substrates in oxidized PETN reductase We noted previously from structures of...
... attached to the disubstituted GalNAcII residue as a monosaccharide side chain Correlations ofthe b-linked sugars inthe main chain were difficult to interpret because of close positions ofthe H1 ... and lysine The D configuration of GalA and GalN was determined by GLC ofthe acetylated (S)-2-butyl glycosides and the L configuration of lysine by GLC ofthe acetylated (S)-2-butyl ester The D ... is 50 ng from the complete set of Proteus strains, including 37 strains of P mirabilis and 28 strains of P vulgaris belonging to 49 Proteus O-serogroups as well as 133 strains of P penneri From...
... containing an extracellular ANPbinding domain (ECD), a transmembrane domain, and an intracellular domain consisting of an ATP-binding regulatory domain and a GCase catalytic domain [8] ANP binding ... change in its environment On the other hand, if the ECD assumes the tt dimer structures, no change is expected inthe Trp environment in response to ANP binding On the basis ofthe above structure ... maintaining the two-fold symmetry axis inthe dimerized complex The orientation of each EM construction is based on the closeness ofthe fit to the respective X-ray structure as shown in Fig The...
... proposed for this structure [37] The overall shape of Ab-(1–42) is strongly reminiscent ofthestructureofthe fusion domain ofin uenza hemagglutinin (HA_fd), recently determined in detergent micelles ... of all, to evaluate the role of Ab-(1–42) inthe interaction with the membrane Thestructureof Ab-(1–42) found in aqueous hexafluoroisopropanol, a medium that mimics the lipidic environment of ... pH in 5% acetonitrile), and a linear gradient from to 20% of solvent B (5 mM ammonium acetate, pH in 90% acetonitrile) in 25 was adopted for the elution ofthe peptide The fraction containing the...
... hydrogen-bonded to the side chain of His140, which is one ofthe His residues coordinating the T2 copper inthe trinuclear center C-terminal sequencing ofthe mature MaL showed that the C-terminus is post-translationally ... preventing binding of oxygen We analyzed the azide inhibition and determined the inhibition constants for sodium azide, in order to see the effect ofthe mutation (L559A) on the binding properties in ... show the critical role ofthe last amino acids inthe C-terminus of MaL Deletion ofthe four last amino acids strongly reduced the expression ofthe protein in T reesei and S cerevisiae Furthermore,...
... view ofthe interactions of papain with loop L4 of chagasin and the N-terminal segment of cystatin B (D) Zoom -in view ofthe interactions of papain with loop L2 of chagasin and loop L1 of cystatin ... indicating that the chagasin molecule is slanting towards the R domain The angle of approach of cystatin B is )12.7°, and the inhibitor molecule is inclined towards the L domain ofthe enzyme The difference ... interaction is supported by a water molecule linking the N atom of G66 of chagasin and the main-chain O atom of D158e of papain Inthe cystatin B complex, an equivalent carbonyl is involved in...
... required Inferential work le relatively transparent The event of John's entering the o n c e results inthe state of his being inthe ofrice: this le part ofthe lexical meaning of enter The temporal ... their mother to fix the tail v-~hveof the windmilL b Inthe great expanse ofthe prairie where they lived, the high tower ofthe windmill was the only real landmark (Worline, 1956:1) Given the conceptual ... according to their internal dynamics, the stability of their parameters and the resources they consume (Part ofthe internal dynamics, inthe presence of a conscious agent, is the degree of volitional...
... solvation, owing to increased water-binding capacity This may allow the protein to remain in a hydrated state, preventing the binding of inorganic cations inthe high-salt solution, and also preventing ... enzyme (Fig 4); there is little correspondence inthe amino acids that are involved inthe recognition ofthe functional groups ofthe ligands Moreover, in GGT the a-carboxyl group ofthe glutamate ... and therefore the ligand bound to CapD is exposed to solvent A notable difference between the two enzymes can be seen inthe manner of Fig Comparison ofthe binding modes ofthe ligands The structures...
... demonstration ofthe relationship between the evolution ofthe primary structureofthe N-terminal regions of TTR and the biological function of TTR 4014 Results Synthesis of recombinant human TTR Inthe ... recombinant TTRs as tetramers Analysis of binding to retinol-binding protein and thyroid hormones showed that the recombinant TTRs retained its function as binding protein for retinol-binding protein ... TTR is only synthesized inthe liver during development inthe egg and in hatchlings and only inthe choroid plexus ofthe adult Thus, it is difficult to obtain the native crocTTR in sufficient amounts...