... that aquantum theory of gravity brings with it a quantum theory of geometry. At thePlanck scale, quantum excitations of geometry are structured like a branchedpolymer, and familiar quantities ... more than the mass of theSun in a radius of 10 kilometers. Spacetime in their vicinity is more highlycurved than in any place in the universe other than the big bang and black holes,and binary ... approximations.• The development of current ideas in string theory and the quantum theory of geometry to achieve a finite, workable union of quantum mechanics, gravity,and the other forces of nature, potentially...
... Kruus2,Juha Rouvinen1and Nina Hakulinen11 Department of Chemistry, University of Eastern Finland, Joensuu, Finland2 VTT Technical Research Centre of Finland, Espoo, FinlandKeywordsascomycete; ... crystal structures of laccases from fungi andbacteria are available, but ascomycete types of fungal laccases (asco-lac-cases) have been rather unexplored, and to date only the crystal structure of ... crystal structureof TaLcc1 does not have a chloride attached tothe T2 copper, as observed in the crystal structureof MaL. The unique fea-ture of TaLcc1 and MaL as compared with other laccases structures...
... mightaccountformorewhiteandAsiangraduatesbeinginmanagement compared to theirAfrican and colouredcounterparts. The proportion of whiteandAsiangraduateswithineachcategory of number of yearsworkedwasnotashighasthat of otherracegroupsatthetime of thesurvey(Table8).Table8:Number of yearsworkedbythoseinmanagement,byraceNumber of yearsworkedAsian ... www.hsrcpress.ac.za6PercyMoleke7InequalitiesinHigherEducationandthe Structureof theLabourMarketdisadvantage of Africansandcolouredsinthelabourmarketemergedclearlyinthisanalysis.Infieldswithaprofessionalfocus,insignificantdifferencesexistedinterms of ... followed by Asians (19,6%),Africans(10,8%)andcoloureds(10,6%)(Table7).Table7:Level of function,byraceLevel of function Asian African Coloured White OtherManagerial 19,6 10,8...
... the Canadian Institutes of Health Research (Operating Grant MOP 43982 toGH), and by the Natural Sciences and EngineeringResearch Council of Canada (to GH). DSL wasthe recipient ofan Ontario ... NMR structureofan immunodominant epitope of myelin basic proteinConformational dependence on environment ofan intrinsicallyunstructured proteinChristophe Fare`s1,*, David S. Libich1and ... MBP maintainsthe compaction of the sheath by anchoring the cytoplas-mic faces of the oligodendrocyte membranes [2], and is acandidate antigen for T cells and autoantibodies inmultiple sclerosis...
... on the basis of side-chain packing criteriafrom a modelled structureof the enzyme resulted in restor-ation of the energy of activation to the levels of the nativeenzyme and in an increased ... significant decrease of DH#with an unavoidable concurrent decrease of TDS#.Theslope of the Arrhenius plot, in the temperature range5–15 °C, corresponds to an approximately threefoldincrease of ... studies of wild-type and mutant alkaline phosphatases.(A) Temperature dependence of kcat of TAB5 (d), mutants G261A(r), G261A/Y269A (j)andE.coli (·) alkaline phosphatases attemperature range...
... [211–215], Na+channels[216,217], K+channels [218], other unidentified chan-nels [203–207] and many members of the TRP family of channels (see below). In extreme cases, channelselectivity ... &Luckhoff A (2002) Activation of the Cation ChannelLong Transient Receptor Potential Channel 2(LTRPC2) by Hydrogen Peroxide. A splice variantreveals a mode of activation independent of ADP-ribose. ... phylogeny, and functions of the TRP superfamily of cation channels. Sci STKE2001, RE1.255 Chandrasekaran K, Mehrabian Z, Li XL & Hassel B(2004) RNase-L regulates the stability of mitochondrialDNA-encoded...
... lmol of EDTA or an equimolecular amount of DM43to the enzymes.Statistical analysisResults represent mean ± SEM (n ‡ 4). Data were statis-tically evaluated by Analysis of Variance (ANOVA), ... physicochemicaland biological properties of DM64, an antimyotoxic proteinfrom opossum serum. DM64 is an acidic protein showing15% glycosylation and with a molecular mass of 63 659 Dawhen analysed ... loops of these extra Ig-like domains, indicatingthat the shift from an antihemorrhagic to an antimyotoxicmolecule could be the result of a combination of these twofeatures, presence of the...
... avariety of post-translational modifications, ranging fromextensive formation of dehydro residues and lanthioninebridges in the case of lantibiotics (e.g. nisin A) to simplecleavage of a leader ... importance of this helix for membrane-boundreceptor recognition and consequent antimicrobial activity[2,10]. For example, Fimland et al. [42] have shown thatinterchange of large domains of different ... Council of Canada, the Alberta Heritage Foundation forMedical Research, CanBiocin Ltd (Edmonton, AB), and the CanadaResearch Chair in Bioorganic and Medicinal Chemistry.References1. O’Sullivan,...
... one another than to any other profile in the data set. The profiles of G can be summarized by a vector s whose dimensionality is that of the data, and each of whose elements contains the mean ... prophethood of Mohamed and the coming resurrection, and remind humanity of the past prophets and events of their times. On the other hand, the Madinan suras outline ritualistic aspects of Islam, ... definitive cluster analysis of the Qur an, but to develop an approach to doing so. One particular combination of distance measure and cluster definition was therefore chosen at random and applied...
... point, see G. E. M. Anscombe, ‘Causality and Determina-tion’, in her Metaphysics and the Philosophy of Mind. Of course, the ‘Humean’ defini-tion of causation in terms of ‘constant conjunction’, ... asif he thinks that a human person is some sort of combination of an immaterial soul and a physical body, which stand to oneanother in a rather mysterious relation of ‘substantial union’.I shall ... 1.Contentsviii4Mentalcontent69Propositions70Thecausalrelevanceofcontent74Theindividuationofcontent79Externalisminthephilosophyofmind82Broadversusnarrowcontent84Content,representationandcausality89Misrepresentationandnormality92Theteleologicalapproachtorepresentation95Objectionstoateleologicalaccountofmentalcontent99Conclusions1005Sensationandappearance102Appearanceandreality103Sense-datumtheoriesandtheargumentfromillusion107Otherargumentsforsense-data110Objectionstosense-datumtheories112Theadverbialtheoryofsensation114Theadverbialtheoryandsense-data116Primaryandsecondaryqualities119Sense-datumtheoriesandtheprimary/secondarydistinction121Anadverbialversionoftheprimary/secondarydistinction125Docolour-propertiesreallyexist?126Conclusions1286Perception130Perceptualexperienceandperceptualcontent131Perceptualcontent,appearanceandqualia135Perceptionandcausation137Objectionstocausaltheoriesofperception143Thedisjunctivetheoryofperception145Thecomputationalandecologicalapproachestoperception149Consciousness,experienceand‘blindsight’155Conclusions1587Thoughtandlanguage160Modesofmentalrepresentation162The‘languageofthought’hypothesis164Analogueversusdigitalrepresentation167Imaginationandmentalimagery169Thoughtandcommunication175Doanimalsthink?178Naturallanguageandconceptualschemes183In this book Jonathan Lowe offers a lucid and wide-ranging introduction to the philosophy of mind. Using...