structure and interpretation of computer programs ebook
Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf
... A (1979) Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin.J Cell Biol 83, 403–427.Active chromatin and DNase I hypersensitive ... withbinding of both MOF and Tip60 (equivalent to Esa1in yeast NuA4) [124,130]. However, in human cellsdepletion of MOF, but not Tip60, results in reducedglobal levels of AcH4-K16 and defective ... acetylation and deacetyla-tion, and transient recruitment of remodellers and transcription factors.A cycle of transcription commences with the recruit-ment of transcription factors and co-factors...
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Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... α-FlagKIND2-FlagΔGEF-FlagABFig. 1. Domain structure of the MAP2-asso-ciated RasGEF v-KIND and its dendritic tar-geting via KIND2 domain. (A) Structures of the v-KIND. KIND1, KIND2, coiled-coil (CC),RasN and RasGEF domains. ... full-lengthv-KIND; DKIND1, deletion of KIND1;DKIND2, deletion of KIND2; DKIND1 + 2,deletion of both KIND1 and KIND2; DRasN,deletion of RasN; DGEF, deletion of RasGEF; KIND1, KIND1 domain; KIND2,KIND2 ... MAP2 cDNA and its derivativesgenerated by PCR were cloned into pGEX-4T-2. The KINDdomains of Spir-2 and PTPN13 were generated by RT-PCR and inserted into pEGFP-C1 and pGEX-4T-2. The N- and C-terminal...
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Tài liệu Body Size: The Structure and Function of Aquatic Ecosystems pptx
... predicting,measuring and understanding the roles of different kinds of organisms in the flux and storage of elements in ecosystems. The total biomass per unit area, W,issimply the sum ofthe body mass of all ... & Jumars,1991) and the problems of dealing with extremely small particles.It is reasonable to expect tuning of the size of filtering structures and collect-ing elements to profitable prey size ... detected and the processes that appeared to be important, and (ii) to compare freshwater and marine ecosystems. In Body Size: The Structure and Function of Aquatic Ecosystems,both those questions of...
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Tài liệu Báo cáo khoa học: Structure and function of plant aspartic proteinases pptx
... (1990) The structure and function of the asparticproteinases. Annu. Rev. Biophys. Biophys. Chem. 19, 189–215.2. Dunn, B.M. (2002) Structure and mechanism of the pepsin-likefamily of aspartic ... and C-terminal domain in red. (B) Ribbon representation of the structure of the PSI domain of barley prophytepsin [25] (N-terminal domain,blue; C-terminal domain, red). (C) Model structure of ... isoforms by the excision of the prosegment and of most of the PSI [21]. Conversely to what has been foundin vivo [31], heavy and light chains of the processed forms of recombinant cyprosin are...
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Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc
... determination of the subunitcomposition of the nAChRs involved has been hindered bythe lack of selective ligands and imperfect correlationsbetween the characteristics of native and heterologouslyexpressed ... function and composition of the neuronal nAChRs. This objective hasbeen greatly hampered by a lack of selective ligands. Thesnake neurotoxin a-bungarotoxin (a-BTX) is one of thefirst and most ... elucidation of nAChR structure and function.Ó FEBS 2004 Pharmacology of neuronally active a-conotoxins (Eur. J. Biochem. 271) 2307b2, b3 and to a minor extent b4 subunits [9,86,87], aspossible candidates....
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Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf
... to T hr49) and TmAFP (blue, residuesAsn29fiGly41). Letters de note the five residues of on e of the threesides of s bwAFP o r s ix residues of on e of two sides of T mAFP. T hestrands that make ... Overlap of X-ray structure with 5 °C NMR structure using the main chain of residues Ser12 fiThr70 in t he structure a lignment. (B) O verlap of theX-ray structure with the 30 °C NMR structure ... [31,32,36] and their three-dimensional structures were determined [34,37–40]. Insubsequent sections, we describe the structure and dynamics of each protein, and present a comparison of s bwAFP and TmAFPwitheachotherandwithproteinsthathaveasimilar...
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Tài liệu Báo cáo khoa học: Complete subunit sequences, structure and evolution of the 6 · 6-mer hemocyanin from the common house centipede, Scutigera coleoptrata pptx
... submitted to MALDI-TOF analysis and assigned to distinct subunits.Fig. 1. SDS/PAGE and immunoblotting of S. coleoptrata hemocyanin.About 10 lg of total hemolymph protein (HL) and 3 lgofpurifiedhemocyanin ... SDS/PAGE and stained by Coomassie brilliant blue. The twohemocyanin bands were cut out and dispersed. About100 lg of hemocyanin was used for the immunization of rabbits. For determination of the ... subunits and HcX, plus 6–45 bp of the respective 5¢ untranslatedregions and the entire 3¢ untranslated regions. The standardpolyadenylation signals (AATAAA) and the poly(A)-tails of different...
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Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot
... orm of b strand [18].The positive bands at » 1675 cm)1in the amide I r egion of the ROA spectra of b-andj-casein, which originate mainlyin the peptide C O stretch, are characteristic of ... theme of PPII structure and rheomor-phism is explored by a comparative ROA study, supple-mented with DSC, of caseins, synucleins and tau, togetherwith several mutants of a-synuclein and tau ... agreement between our presentresults and the earlier interpretations of the U VCD spectra of b-andj-caseins (see above) to the fact that t he basis s ets of protein UVCD spectra used in the analysis...
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Tài liệu Báo cáo khoa học: "The Structure and Process of Talking About Doing" pdf
... model of the role of point of view in problem solving. SUMMARY We have reported here a three pronged approach to the study of problem solving action and report: I) the collected of data ... of data on problem solving and talk about problem solving, 2) development of a process model of these behaviors, and 3) use of coding techniques to extract traces of "critical phenomena" ... efforts on two types of problem solving phenomena: the changes in the problem solver's organization of the problem ("point of view"), and systematic multl-utterance structures used...
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Tài liệu Concepts, Techniques, and Models of Computer Programming pot
... to grasp yet it isessential for defining precise specifications of what programs do.Like Structure and Interpretation of Computer Programs, by Abelson, Sussman,& Sussman [1, 2], our book ... improved versions of Java).The kernel language approachPractical programming languages scale up to programs of millions of lines of code.They provide a rich set of abstractions and syntax. How ... Mostafa, Luis Quesada, and Fred Spiessens for their efforts in proofreading and testing the example pro-grams. Finally, we thank the members of the Department of Computing Science and Engineering at...
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Tài liệu Báo cáo Y học: The solution structure and activation of visual arrestin studied by small-angle X-ray scattering pot
... phosphorylation of the C-terminus of R* and binding by arrestin. Phosphorylation somewhatdecreases the ability of R* to signal transducin. Rapid shut-off of R* signalling is then accomplished by binding of arrestin ... forwardscattering of monomeric arrestin, the forward scattering from a mixture of monomers and dimers is:Ið0ÞTotal¼ fMIð0ÞMþ 2fDIð0ÞMð1Þwhere fM and fDare the mass fractions of monomer and dimer, ... concentrations of monomer and dimer, respectively. The Kdcanalsobeexpressed in terms of the total mass concentration of protein, [arrestin]total(in mgÆmL)1), the mass fraction of monomer, fM, and...
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Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf
... minidomain and the zinc-binding domain of the zinc finger protein Ynr046w [25] (Fig. 8). The fit of the heavy atoms (Ca, C, and N) from threeb-strands and the a-helices of both the closed and theopen ... TA, Gargaro AR &Feeney J (1999) Structure and dynamics in solution of the complex of Lactobacillus casei dihydrofolate reduc-NMR structure and function of the eRF1 C-domain A. B. Mantsyzov ... variation of pH in the rangebetween 6.3 and 7.7, of ionic strength between 25 and 100 mm NaCl and of temperature between 278 and 313 K did not lead to any detectable change in thepopulations of the...
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Báo cáo khoa học: Staphylococcus aureus elongation factor G – structure and analysis of a target for fusidic acid pdf
... helices AV and BVat the surface of domain V. Gly621 and Gly617 are in the area of contact with the 1095 and 2473 regions of 23S RNA. The two helicesare facing the ribosome, and the four-stranded ... 666 and 670, within one b-strand of domain V, are also important for interdomain interac-tions. The N-terminal part of the strand interacts withthe N-terminal part of helix CGin domain G, and ... occupancy of GDP in the nucleotide-bindingsite. Therefore, we present here the apo structure of S. aureus EF-G.Overall structure and comparison with previousEF-G structuresAll five domains of S....
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Báo cáo khoa học: Evolutionary changes to transthyretin: structure and function of a transthyretin-like ancestral protein doc
... struc-tures of these proteins, all tetrameric, showed signifi-cant similarity to the published structures of transthyretin. By way of example, a comparison of the structure of S. dublin TLP with the structures ... dublin TLP and zebrafish TLP are found in the flex-ible portions of strands B and C that protrude towardsthe solvent and in the conformation of the long loopconnecting strands D and E [17]. ... Interruptions in the b-strands A, G and H are also observed in TLP structures as a result of alterations to the formation of hydrogen bondsbetween strands. The carbonyls of residues V104 and P105 (zebrafish...
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