stage 1 nonsmall cell lung cancer survival rate
Báo cáo khoa học: "Large volume unresectable locally advanced nonsmall cell lung cancer: acute toxicity and initial outcome results with rapid arc" potx
... RACTV(mean+1SD)PTV(mean+1SD)Volume [cm3] 299 ± 17 5 818 ± 206Mean [%] 10 0 10 1.0 ± 1. 2 10 0.0 ± 0.0D1% [%] < 10 7% 10 5.6 ± 1. 7 10 5.6 ± 1. 6D5-95% [%] Minimize 6.3 ± 1. 4 9 .1 ± 1. 3D99% [%] ... 8.9Contra-lateral lung Volume [cm3] - 19 45 ± 517 Mean [Gy] < 15 Gy 13 .7 ± 3.9V20Gy[%] < 20-30% 21. 1 ± 6 .1 Spinal CordVolume [cm3] -39 16 D 1% [Gy] < 45 Gy 39.5 ± 4.0HeartVolume [cm3] - 715 ... 96.7 ± 1. 8 91. 6 ± 2.2V95% [%] 10 0 99.6 ± 0.6 94.6 ± 4 .1 V107% [%] 0 0.7 ± 1. 3 0.7 ± 1. 7Table 3 Summary of DVH analysis for organs at riskObjective RAIpsi-lateral lung Volume [cm3] - 17 17 ±...
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Báo cáo khoa học: " Validation of an elastic registration technique to estimate anatomical lung modification in NonSmall-Cell Lung Cancer Tomotherapy" docx
... 6. 81 4.59 ± 1. 75 10 .17 elastic 5. 51 ± 2.44 8. 51 2. 81 ± 1. 06 4.09 4.2 ± 1. 45 6 .15 4 .17 ± 1. 35 8. 51 4. rigid 5 5.39 ± 2. 51 8.33 5 7.95 ± 2.62 11 .13 4 9.86 ± 5.34 14 .46 7.73 ± 2.24 14 .46elastic ... 3.73 11 .22 5 .1 ± 2.87 8.35 4.58 ± 0.67 11 .225. rigid 5 3.08 ± 1. 13 4.57 4 2.87 ± 1. 38 3.83 2 2.99 ± 1. 64 4 .15 2.98 ± 0 .11 4.57elastic 3 .16 ± 0.94 4.55 2 .14 ± 1. 00 3.63 2.52 ± 2 .13 4.02 2. 61 ± ... 0.95 1. 59 0.33 0.95 -0. 41 0.39 0.964. rigid -0.55 0.95 0.90 -1. 44 1. 30 0.89 -11 .14 1. 56 0.82elastic 0.48 0 .18 0.93 -1. 15 0.28 0.94 -3 .11 0.88 0.935. rigid 7.64 3. 01 0.89 0.90 2.68 0. 91 -16 .16 ...
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Báo cáo khoa học: "The effect of bioequivalent radiation dose on survival of patients with limited-stage small-cell lung cancer" pdf
... interests.Received: 16 January 2 011 Accepted: 19 May 2 011 Published: 19 May 2 011 References 1. De Ruysscher D, Vansteenkiste J: Chest radiotherapy in limited -stage small cell lung cancer: facts, questions, ... 0. 713 Male 57( 81. 4)* 10 7(79.3)Female 13 (18 .6) 28(20.7)KPSMedian 80 80 0 .16 3Range 60 -10 0 60 -10 0Weight loss>5% 0 .17 8Yes 21( 30.0) 29( 21. 5)No 49(70.0) 10 6(78.5)LDH 0. 517 ≤220 IU/L 35(43 .1) ... small -cell lung cancer. Clin Lung Cancer 2003, 4:339-346.doi :10 .11 86 /17 48- 717 X-6-50Cite this article as: Xia et al.: The effect of bioequivalent radiation doseon survival of patients with limited-stage...
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Báo cáo hóa học: " Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer" pdf
... 29Histologyadeno 69 61 57 217 60SCC 1 0 7 11 2 0LCC 5 0 4 11 0others 3 0 2 0 0EGFRexon 19 29 10 18 21 55 58 21 exon 21 27 0 12 14 18 56 23wild-type 22 51 29 296 14 5 16 7 16 IHC sensitivityoverall ... sequencingEGFR EXON 19 DELETION SUBTYPE 0 1+ 2+ 3+ 15 bpN =17 0 /17 (0%) 0 /17 (0%) 2 /17 (11 %) 15 /17 (89%)9bpN=42/4 (50%) 2/4(50%) 0/4 (0%) 0/4 (0%) 12 bpN =1 1 /1 (10 0%) 0 /1 (0%) 0 /1 (0%) 0 /1 (0%) 18 bpN=54/5 ... bpN=54/5 (80%) 1/ 5 (20%) 0/5 (0%) 0/5 (0%) 21 bpN =1 1 /1 (10 0%) 0 /1 (0%) 0 /1 (0%) 0 /1 (0%)24 bpN =1 1 /1 (10 0%) 0 /1 (0%) 0 /1 (0%) 0 /1 (0%)Figure 2 IHC staining of tumor samples from lung cancer patients....
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Báo cáo khoa học: "Clinical outcomes of stereotactic body radiotherapy for stage I non-small cell lung cancer using different doses depending on tumor size" ppsx
... (78)GenderMale 84 1 54 29Female 40 1 31 8Performance status0 65 2 47 16 1 48 0 31 17 211 074Tumor size (mm)Range (median) 12 -55 (27) 12 , 14 15 -34 (24) 31- 55 (35)OperabilityOperable 40 2 27 11 Non-operable ... 46 18 Squamous cell carcinoma 35 0 19 16 Unclassified NSCLC 13 0 10 3Unproven 10 0 10 0Tumor locationCentral 29 0 18 11 Peripheral 95 2 67 26Abbreviations: NSCLC = non-small cell lung cancer. Baba ... Baba 1, 2*, Yuta Shibamoto 1 , Hiroyuki Ogino 1 , Rumi Murata 1 , Chikao Sugie 1 , Hiromitsu Iwata 1 , Shinya Otsuka 1 , Katsura Kosaki 1 , Aiko Nagai 1 , Taro Murai 1 , Akifumi Miyakawa 1 AbstractBackground:...
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Báo cáo khoa học: " Comparison of outcomes in patients with stage III versus limited stage IV non-small cell lung cancer" docx
... manuscript.Received: 4 April 2 011 Accepted: 30 June 2 011 Published: 30 June 2 011 References 1. Jemal A, Siegel R, Xu J, Ward E: Cancer Statistics, 2 010 . CA Cancer J Clin2 010 , 60(5):277-300, Epub 2 010 Jul 7.2. ... Oligometastases, Non-Small Cell Lung Cancer BackgroundNon-small cell lung cancer (NSCLC) is the leadingcause of cancer mortality in the United States [1] .Patients with stage IV NSCLC typically ... 6:80http://www.ro-journal.com/content/6 /1/ 80Page 2 of 7 RESEARC H Open AccessComparison of outcomes in patients with stage IIIversus limited stage IV non-small cell lung cancer Praveena Cheruvu 1 , Su K Metcalfe 1 , Justin...
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Báo cáo khoa học: "Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study" pps
... None Minor< ;1. 15 1. 15 1. 25 <8 8 10 <55 55–60 <4 4–6 0–20< ;1. 15 1. 15 1. 25 <7 7–8 <65 65–70 <6 6–8 20–40< ;1. 10 1. 10 1. 20 <6 6–6.5 <65 65–75 <8 8 10 >40Type ... < ;12 12 14 <65 65–75 <5 5–8 0–20< ;1. 15 1. 15 1. 25 <9 9 11 <70 70–80 <6 6 10 20–40< ;1. 10 1. 10 1. 20 <6 6–8 <70 70–80 < ;10 10 15 >40 ... PTV (R 10 0%) from a total of 22 patients with stage IA tumours and 4 patients with stage 1B tumours (with PTVs of 59 cc, 85 cc, 10 7 cc and 10 8 cc).0 25 50 75 10 0 12 50.9 1. 0 1. 1 1. 2 1. 3 1. 4...
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báo cáo hóa học:" Randomized phase II study with two gemcitabine- and docetaxel-based combinations as first-line chemotherapy for metastatic non-small cell lung cancer" docx
... carcinoma 14 (35) 12 (29.3)Other NSCLC 4 (10 ) 6 (14 .6)Site of disease Lung ± lymph nodes 14 (35) 14 (34 .1) Lung and 1 metastatic site 12 (30) 15 (36.6) Lung and ≥ 2 metastatic sites 9 (22.5) 10 (24.4)Extra-pulmonary ... (%)Leukopenia 6 (15 ) 9 (23) 4 (10 ) 3 (8) 2 (5) 2 (5)Anemia 12 ( 31) 1 (3) 0 - 5 (13 ) 0 - 0 -Thrombocytopenia 1 (3) 2 (5) 0 - 2 (5) 0 - 0 -Neutropenia 3 (8) 7 (18 ) 14 * (36) 6 (16 ) 4 (11 ) 7†(8)Non ... withadvanced non-small -cell lung cancer. The European Organi-zation for Research and Treatment of Cancer Lung Cancer Cooperative Group. J Clin Oncol 19 98, 16 : 213 3- 214 1.7. Crino L, Scagliotti...
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Báo cáo hóa học: "Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins" ppt
... colorectal cancer. BMC Cancer 2 010 , 26 ;10 :11 7. 31. Marur S, D’Souza G, Westra WH, Forastiere AA: HPV-associated head andneck cancer: a virus-related cancer epidemic. Lancet Oncol 2 010 , 11 :7 81- 789.32. ... from human normal lung, (GSM14 018 5-GSM14 018 9), and five sets from humanSCLC, (GSM14 017 6-GSM14 018 0) [20] and analyzeddata set s with GeneSpring 10 . Of the 8793 genes exam-ined, 5 61 were differentially ... 55% had HPV16 /18 DNAcompared with 11 % of non cancer control subje cts.Additionally HPV 16 /18 DNA has been uniformlydetected in lung tumor cells but not in the adjacentnoninvolved lung tissue...
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Báo cáo hóa học: "Prognostic Impact of MiR-155 in Non-Small Cell Lung Cancer Evaluated by in Situ Hybridization" pot
... 47Pathological stage <0.0 01 I 15 7 47 19 0 71 II 13 6 41 61 51 IIIa 42 12 17 23Tumor status <0.0 01 1 85 25 19 0 742 18 8 56 84 5736 219 2536Nodal status <0.0 01 0 232 69 19 0 66 17 62335432 27 8 18 18 Surgical ... 60Former 10 5 31 71 54Performance status 0. 013 ECOG 0 19 7 59 NR 63ECOG 1 120 36 64 52ECOG 2 18 5 25 33Weight loss 0. 71 < ;10 % 303 90 12 7 58> ;10 % 32 10 98 57Histology 0.028SCC 19 1 57 NR ... 95 34 47 41 LCC 31 9 98 56BAC 18 NR 71 Differentiation <0.0 01 Poor 13 8 41 47 47Moderate 14 4 43 19 0 64Well 53 16 NR 68Surgical procedure 0.004Lobectomy + Wedge* 243 73 19 0 61 Pneumonectomy...
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báo cáo hóa học: " Health state utilities for non small cell lung cancer" pot
... 9.8%Student 15 .0% 1. 9%Other 11 .0% 2.3%Education – leaving ageNo Formal Qualifications 8.0% -GCSE/O Levels (16 yrs) 17 .0% -A Levels (18 yrs) 26.0% -Vocational or work based 11 .0% -University ... 0. 016 33 99 -5. 51 <0.00 01 Fatigue -0.07346 0. 018 49 99 -3.97 0.00 01 Nausea & vomiting -0.04802 0. 016 18 99 -2.97 0.0038Diarrhoea -0.0468 0. 015 53 99 -3. 01 0.0033Hair loss -0.04495 0. 014 82 99 -3.03 ... 2002, 12 2: 21- 30. 10 . Cooley ME, Short TH, Moriarty HJ: Symptom Prevalence, dis-tress, and change over time in adults receiving treatment for lung cancer. Psycho-oncology 2003, 12 :694-708. 11 . Brown...
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Báo cáo toán học: "Molecular Predictors of EGFR-TKI Sensitivity in Advanced Non–small Cell Lung Cancer" ppsx
... 20 01; 18 (6): 10 59-68. 3. Travis WD, Travis LB, Devesa SS. Lung cancer. Cancer. 19 95; 75 (1 Suppl): 19 1-202. 4. Franceschi S, Bidoli E. The epidemiology of lung cancer. Ann Oncol. 19 99; 10 ... technology 91% 3 (14 %) 16 (76%) 0 7.7 Sunaga N, et al (32) 21 Japanese Sequencing 91% 3 (14 %) 13 (62%) 3 (14 %) 12 .9 Inoue A, et al (34) 16 Japanese Sequencing 88% 0 12 (75%) 2 (13 %) 9.7 Asahina ... much benefit is enough? J Clin Oncol. 19 93; 11 (10 ): 18 66-72. 9. Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell. 2000; 10 3(2): 211 -25. 10 . Yarden Y, Sliwkowski MX. Untangling...
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Báo cáo khoa học: "Pathological complete response induced by first-line chemotherapy with single agent docetaxel in a patient with advanced non small cell lung cancer" pptx
... small cell lung cancer Ferdinando Riccardi 1* , Giuseppe Di Lorenzo 1 , Carlo Buonerba 1 , Guglielmo Monaco2, Roberto Monaco3,Mimma Rizzo 1 , Sarah Scagliarini 1 , Florinda Scognamiglio 1 , ... Scognamiglio 1 , Marilena Di Napoli 1 , Giacomo Carteni’ 1 AbstractBackground: Defining the optimal treatment for patients with inoperable non small cell lung cancer (NSCLC),presenting with metastatic ... 5-year survival of 20-30%, the majority of patients with stage IIIA-N2 and IIIB-N2 tumors cannot undergo up-front surgical resection and present a 5-year survival rate of about 5% [1] . There...
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Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot
... = 11 ) pvalue*MLD 11 .59(6.53 -18 .11 ) Gy = 11 .26, SD = 2. 81 = 14 . 91, SD = 2. 91 0.0 01 NTCP 2.33% (0. 51- 9.68%) = 2. 51, SD = 1. 73 = 5.94, SD = 2.400.0 01 V5 58.73% (32.89-97.65%) = 58.43, SD = 16 .57 ... SD = 12 .470.006V10 42 .16 %(25.28-83.34%) = 41. 13, SD = 12 .69 = 52.42, SD = 11 .050.0 01 V15 29.53% (16 .46-58. 51% ) = 28.94, SD = 9 .12 = 38.30, SD = 7.650.005V20 18 .15 % (9.46- 31. 08%) = 18 .59, ... = 4.640. 011 V40 8.20% (3.29 -13 . 61% ) = 5. 91, SD = 2.48 = 9.26, SD = 3.750. 015 V45 7.42% (2.73 -10 .99%) = 4. 41, SD = 2.25 = 6.54, SD = 3.470.007V50 7.07% (1. 94-8.82%) = 3 .15 , SD = 1. 94 = 4.89,...
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