spontaneous remission of intervertebral disc hernia and responses of surrounding macrophages
Báo cáo y học: "The influence of serum, glucose and oxygen on intervertebral disc cell growth in vitro: implications for degenerative disc disease" potx
... disc: cellularity and diffusion of glucose in vitro J Anat 1975, 120:113-130 Gruber HE, Hanley EN Jr: Analysis of aging and degeneration of the human intervertebral disc Comparison of surgical specimens ... EN Jr: Senescence in cells of the aging and degenerating intervertebral disc: immunolocalization of senescence-associated beta-galactosidase in human and sand rat discs Spine 2007, 32:321-327 ... response of NP disc cells was investigated Materials and methods Intervertebral disc cell culture IVD cells were isolated from the NP of adult bovine caudal IVDs by enzymatic digestion and expanded in...
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Báo cáo y học: "Expression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral disc" pdf
... burden of back pain in the UK Pain 2000, 84:95-103 Freemont AJ, Le Maitre C, Watkins A, Hoyland JA: Degeneration of intervertebral discs: current understanding of cellular and molecular events, and ... and its receptor in the human and sand rat intervertebral disc Arthritis Res Ther 2008, 10:R82 22 Olmarker K: Neovascularisation and neoinnervation of subcutaneously placed nucleus pulposus and ... CL, Hoyland JA, Freemont AJ: Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1β and TNFα expression profile Arthritis Res Ther 2007, 9:R77 25 Hoyland JA,...
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Báo cáo y học: "Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration" ppt
... TNF-α decreases expression of aggrecan and type II collagen genes and upregulates mRNA expression of matrix metalloproteinase (MMP)-1, -3 and -13 and ADAM-TS4 (a disintegrin and metalloproteinase ... downregulation of aggrecan and collagen types I and II [7] In this study, we have expanded the investigation to include the effect of TNF-α on matrix and MMP gene expression in normal and degenerate ... expression of IL-1Ra can reduce the activity of MMP-1, -3, -7 and -13 in tissue explants [6], we investigated the effect of TNF-α stimulation on expression of MMPs from each of these groups and compared...
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Báo cáo y học: " Increased expression of matrix metalloproteinase-10, nerve growth factor and substance P in the painful degenerate intervertebral disc" pot
... between any of the genes and age of the donors (MMP-10) in human intervertebral disc Immunohistochemical localisation of matrix metalloproteinase-10 (MMP-10) in human intervertebral disc MMP-10 ... degenerate and metalloproteinase-10 in postmortem (PM) normal, Expression of matrix surgical degenerate human intervertebral disc PM degenerate and surgical degenerate human intervertebral disc Relative ... time, this results in the breakdown of matrix until the disc loses both height and function, and in a large proportion of cases, there is innervation and initiation of the pain response which leads...
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Báo cáo khoa hoc:" Human MMP28 expression is unresponsive to inflammatory stimuli and does not correlate to the grade of intervertebral disc degeneration" doc
... 37 F Disc Herniation L4/5 15 66 M Disc Herniation L5/S1 16 70 F Disc Herniation L5/S1 17 40 F Disc Herniation L4/5 18 55 F Disc Herniation L4/5 19 26 M Disc Herniation L5/S1 20 57 M Disc Herniation ... L4/5 61 M Disc Herniation L3/4 50 M Disc Herniation L5/S1 46 F Disc Herniation L5/S1 51 M Symptomatic Disc Disease L4/5 50 F Disc Herniation L3/4 51 F Disc Herniation L4/5 47 M Disc Herniation ... M Disc Herniation L4/5 10 80 M Disc Herniation L2/3 Results 11 50 M Disc Herniation L4/5 MMP28 gene expression pattern in human disc tissue 12 48 F Symptomatic Disc Disease L4/5 13 61 F Disc Herniation...
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Báo cáo y học: "Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes" pdf
... pattern of expression, that is high expression of ACAN in NP and AC, high expression of type I collagen in AF compared with NP and AC, and high expression of versican (VCAN) in both NP and AF ... Minogue et al., Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes Arthritis Research ... Ultrastructure of the human intervertebral disc I Changes in notochordal cells with age Tissue Cell 1982, 14:359-369 14 Buckwalter JA: Aging and degeneration of the human intervertebral disc Spine...
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HOW TO IMPROVE LISTENING SKILLS IN TOEIC THE CASE OF questions and responses short conversations
... lots of various methods to improve listening skills in TOEIC test, the case of part and It requires much of time and effort However, due to the limitation of time, resources and knowledge of mine, ... case of: Questions- responses, and short conversations To study how to improve listening skill in TOEIC test, the case of: Questions -responses and short conversations Data analysis The number of ... in TOEIC test, the case of: questions -responses and short conversations 16 CHAPTER III: HOW TO IMPROVE LISTENING SKILLS IN TOEIC TEST THE CASE OF: - Questions and Responses - Short conversations...
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A cross cultural study of giving compliments and responses in english and vietnamese
... main purpose of this thesis is to raise the aware of culture gap It is done, focused on the comparison of the ways of giving compliment and responding to compliments between the English and the Vietnamese ... knowledge of language in use or context of conversation for the learners Therefore, “language and culture have to be studied together, and have to be brought into interactive relation in successful discourse” ... importance of study target language is emphasized more than ever We tend to direct our teaching and learning to modern way However, here and there still exists the traditional method of learning and...
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The impact of and responses to HIV/AIDS in the private security and legal services industry in South Africa potx
... economic sectors, and their skills and demographic profiles, is fundamental to an understanding of the impact of HIV/AIDS on various sectors and the demand and supply of labour and skills The economic ... counterparts of 50 years and above (16.4% of males and 9.1% of females respectively); both single males and females reported higher use of condoms (57.1% and 53.0% respectively) than did those of other ... impact of HIV/AIDS on the demand and supply of skills (N = 12) 87 Table 6.1 Profile of employer respondents 92 Table 6.2 Profile of employees by occupational category, population group and sex...
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báo cáo hóa học: " Testing a model of association between patient identified problems and responses to global measures of health in low back pain patients: a prospective study" pdf
... the design of the explanatory model and the study, data collection and analysis, and writing of the manuscript ML contributed to the design of the study, data analysis and writing of the manuscript ... reminded of what they had selected, and asked whether they were now able to it Page of 11 (page number not for citation purposes) Health and Quality of Life Outcomes 2009, 7:74 Responses to Q1 and ... Condition of back Figure of (scores the distribution of task difficulty at 12 according "Worse" and "Much worse" backchange scores Boxplotof to self reported condition of are pooled)months Boxplot of...
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Báo cáo y học: "Degeneration of the intervertebral disc" pptx
... movement of molecules into and out of the disc Aggrecan, because of its high concentration and charge in the normal disc, prevents movement of large uncharged molecules such as serum proteins and ... quality and integrity of the matrix, and thus the mechanical behaviour of the disc itself The integrity of the matrix is also important for maintaining the relatively avascular and aneural nature of ... Cathepsins D and L and several types of MMPs (MMP-1, -2, -3, -7, -8, -9 and -13) occur in human discs; they may be produced by the cells of the disc themselves as well as by the cells of the invading...
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Báo cáo y học: "The role of interleukin-1 in the pathogenesis of human Intervertebral disc degeneration" pdf
... all disc sections, regardless of level of degeneration Investigation of the effect of IL-1 on human IVD cells in alginate culture Issolation of Disc cells Tissue samples were separated into NP and ... (e), according to place of origin in the disc and grade of intervertebral disc degeneration (n = 30) Data are presented as means ± standard errors (as a representative of 95%CI) *P < 0.1,; **P ... production and localization of IL-1 in intact, non-degenerate and degenerate human IVDs themselves, as opposed to herniated disc tissue This study has shown that both isoforms of IL-1 (IL-1α and IL1β)...
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Báo cáo y học: "The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis" pps
... inflammatory and non-inflammatory OA [14] In mouse models of osteophyte formation induced by injections of transforming growth factor-beta or of collagenase, depletion of macrophages by injection of clodronate-laden ... importance of these macrophages for the spontaneous production of proinflammatory cytokines and destructive MMPs in the OA synovium We also assessed, by means of specific neutralisation of macrophage-produced ... (a) and MMPs (b) The data are expressed as percentage of the production of untreated cells, and the standard error of the mean is given (n = 6–7) anisms behind the macrophage stimulation of other...
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Báo cáo y học: "Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration" ppt
... Antoniou J: The role of proteoglycans in aging, degeneration and repair of the intervertebral disc Biochem Soc Trans 2002, 30:869-874 Roughley PJ: Biology of intervertebral disc aging and degeneration: ... Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs Mol Pathol 2002, 55:91-97 Le Maitre CL, Freemont AJ, Hoyland JA: The role of interleukin-1 in the pathogenesis of ... of human intervertebral disc degeneration Arthritis Res Ther 2005, 7:R732-R745 Gruber HE, Hanley EN Jr: Analysis of aging and degeneration of the human intervertebral disc Comparison of surgical...
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Báo cáo y học: "Action of fibroblast growth factor-2 on the intervertebral disc" docx
... Aging and degeneration of the human intervertebral disc Spine 1995, 20:1307-1314 Freemont TJ, LeMaitre C, Watkins A, Hoyland JA: Degeneration of intervertebral discs: current understanding of cellular ... activity of BMP7-mediated PG synthesis Page 10 of 12 (page number not for citation purposes) Figure Schematic of the regulation catabolic and anti-anabolic actions of FGF2 in intervertebral disc of of ... degradation of herniated tissue and encouraging spontaneous disc resorption The expression and role of FGF2 in different stages of degeneration should be further analyzed in human disc tissue,...
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Báo cáo y học: "Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration" docx
... Hoyland JA, Freemont AJ: Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs Mol Pathol 2002, 55:91-97 Le Maitre CL, Freemont AJ, Hoyland JA: Localization of ... 12.5 μL of mastermix (Taqman® Universal PCR mastermix; ABI) and 2.5 μL of template cDNA or gDNA Primers were added to a final concentration of 900 nM and probe to a concentration of 250 nM, and molecular-grade ... p16INK4a at copy numbers of 1.4 and 55.8 copies per 100 ng cDNA from individuals of 30 and 75 years of age, respectively Eleven of the 12 degenerate samples (from both PM and surgical sources, 35.4...
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Báo cáo y học: "Effect of small interference RNA (siRNA) for ADAMTS5 on intervertebral disc degeneration in the rabbit anular needle-puncture model" pptx
... degree of disc injury and radiological and histological appearances of disc degeneration Spine 2005, 30:5-14 29 Masuda K: Biological repair of the degenerated intervertebral disc by the injection of ... maintenance of intervertebral disc structure with a lightly stained matrix and large cells (b, d); the NP was rounded and bloated looking, and consisted of numerous large, vacuolated cells and smaller ... inhibition of intervertebral disc degeneration Int J Exp Pathol 2006, 87:17-28 Le Maitre CL, Freemont AJ, Hoyland JA: The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration...
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Báo cáo y học: "Is a purpose of REM sleep atonia to help regenerate intervertebral disc volumetric loss" pdf
... effect of IVD compression And, when this myotogenous spinal stability Figure Example 1of compressive muscle stabilization of the intervertebral disc Example of compressive muscle stabilization of ... aspects of recuperation during sleep in these mammals Could the finding of mammal size and quantity of sleep be related to the size of the vertebrae and related hydraulic recovery? Page of (page ... mecha- Figure Example 2of lumbar disc height, believed (blue) and proposed (red), across sleep Example of lumbar disc height, believed (blue) and proposed (red), across sleep Page of (page number not...
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Báo cáo y học: "Sustained remission of rheumatoid arthritis with a specific serotonin reuptake inhibitor antidepressant: a case report and review of the literature" ppsx
... mg of escitalopram and has since been maintained on the same His depressive illness and arthritis have been under remission since Discussion SSRIs have been found to be effective in treatment of ... Recently Baune and Eyre [8] reported a case of RA that responded to a combination of SSRIs and antipsychotics Our case differs from Baune and Eyre’s report in that the patient was taken off the risperidone ... platelets and many cell types of the cardiovascular system, in fibroblasts, and in neurons of the peripheral nervous system Yu and colleagues [20] found that peripheral activation of 5-HT2A receptors...
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