some factors impacting the discriminative stimulus effects of drugs

LX Thuy_tính toán vỏ có lỗ giảm yếu và gân gia cường chịu sóng xung kích: Effect of Some Factors on the Dynamic Response of Reinforced Cylindrical Shell with a Hole on Elastic Supports Subjected to Blast Loading

Ngày tải lên : 02/11/2016, 22:48

... rapidly (Figure 13) x 10 2.5 4.4 The Effects of the Height of Rib Stress [N/m ] Xicmax 1.5 Assessing the effects of the height of the stiffening rib, the authors examined the problem with hg changes: ... values of hg American Journal of Civil Engineering 2016; 4(6): 306-313 assessment of the influence level of these factors to the dynamic response of the mentioned shell The results of the paper ... seat connection, so when the stiffness of the shell increases making more load transfers to the elastic seating which leads to the increase of the total displacement of the calculated point In...

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Báo cáo khoa học: The in vitro effects of CRE-decoy oligonucleotides in combination with conventional chemotherapy in colorectal cancer cell lines potx

Ngày tải lên : 07/03/2014, 15:20

... irrespective of the chemotherapy used Consequently, the effects of 5-FU on the cell lines are presented, which were most representative of the effects seen with any of the three drugs studied ... of the cell cycle We next investigated the effect of combining CDO with the chemotherapeutic drugs 5-FU, SN38 and etoposide in the two CDO-sensitive cell lines There was neither enhancement of ... of p53 status [18,19], and accompanied by the hallmarks of apoptosis [20], which together suggests a more profound interaction The aims of the present study were threefold: ﬁrst, to explore the...

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Báo cáo khoa học: Hepatocyte-speciﬁc interplay of transcription factors at the far-upstream enhancer of the carbamoylphosphate synthetase gene upon glucocorticoid induction doc

Ngày tải lên : 23/03/2014, 10:20

... factors [12] One of the key determinants of the activation of genes that are under the control of hormone response units is the order and time at which the transcription factors bind to their response ... stabilization of GR binding to the GRU, and thereby stabilization of the interaction of the coregulators interacting with the nucleoprotein complex formed at the GRU This raises the possibility that the ... that these features underlie the absence of binding of transcription factors (Fig 3) and the lack of CPS expression in Rat-1 cells In vivo footprinting of FTO-2B hepatoma cells, on the other...

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Báo cáo sinh học: "Resveratrol prevents inflammation-dependent hepatic melanoma metastasis by inhibiting the secretion and effects of interleukin-18" potx

Ngày tải lên : 18/06/2014, 19:20

... understanding of its mechanisms of action and therefore, for a better assessment of its antitumor efficacy The experimental hepatic colonization of B16 melanoma (B16M) is a unique model for determining therapeutic ... and angiogenesis [18,31] Therefore, the fact that RVL completely abrogated the increase of hepatic blood IL-18 induced by tumorderived factors suggests the potential use of RVL as a hepatic metastasis ... appears to depend on the remarkable inhibitory effect of RVL on the proangiogenic effects of tumoractivated hepatic myofibroblasts [18] In summary, this study uncovers multiple therapeutic intervention...

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Báo cáo nghiên cứu khoa học " CLAM CULTURE DEVELOPMENT IN THE INTERTIDAL AREA: EFFECTS OF STOCKING BIOMASS ON GROWTH, SURVIVAL AND PRODUCTION OF THE TWO SIZES CLAM Meretrix lyrata " docx

Ngày tải lên : 22/06/2014, 12:20

... The estimation of the economic benefit of clam cultured in the intertidal areas is showed in table The net profit is calculated based on the output cost and input cost and price of the clam The ... evaluate the effect of stocking biomass of the two sizes of M lyrata on growth performance and survival to enhance the production and profit of cultivation The other parameters within the culture system ... Microsoft Office EXCEL for Window Results and discussions 3.1 The environment conditions of the experiments The experiment site was situated in the intertidal areas near the estuary where the clams...

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PESTICIDES IN THE MODERN WORLD – EFFECTS OF PESTICIDES EXPOSURE ppt

Ngày tải lên : 28/06/2014, 09:20

... impacts The book is a compilation of works, addressing the various aspects of the pesticides exposure and the related health effects It offers a large amount of practical information to the professionals ... quantitative studies of neurons and the glial cells in the hippocampus The sample of forebrains collected from the groups of treated mice at the end of 7th day (phase I) and at the end of 21st day (phase ... increasing of the farm workers self-protective behaviours and perception of control are discussed, too The alteration of the erythrocyte cholinesterase activity, and the affection of the process of hemostasis...

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Environment and health risks: a review of the influence and effects of social inequalities pptx

Ngày tải lên : 28/06/2014, 23:20

... 2008) .The authors hypothesized that the differential of SO2 exposure between areas might explain the differences observed in the effects but they also evoked the role of other health risk factors ... the Observatory of Women's Health of the Ministry of Health and Social Policy of Spain WHO is grateful for the contributions of the authors of the individual chapters as well as the comments made ... The designations employed and the presentation of the material in this publication not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the...

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Báo cáo toán học: "Some Results on the Relation Between Pluripolarity of Graphs and Holomorphicity" ppt

Ngày tải lên : 06/08/2014, 05:20

... f = f on D1 × D2 and the proof for the case N = is completed Now we assume that the conclusion of the theorem holds for N − ≥ Put k = k1 + · · · + kN From the hypothesis there exists u ∈ P SH(Ck+1 ... (η) = ∂Bn r in which χV denotes the characteristic function of V The lemma is proved Now we are able to prove Theorem 4.1 Proof of Theorem 4.1 From the hypothesis there exists u ∈ P SH(Bn × C), ... DN \ EN The same arguments as in the above proof complete the proof of Theorem 3.2 Holomorphic Graphs of Forelli Type In 1978 Forelli proved that if f : Bn = Bn (0, 1) → C is deﬁned on the unit...

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Báo cáo sinh học: "The long term effects of chemotherapy on the central nervous system" docx

Ngày tải lên : 06/08/2014, 18:21

... vulnerable, population of patients Chemotherapy-induced cognitive decline in the absence of radiation The best data on the cognitive effects of chemotherapy alone have come from studies of children with ... are planned that further reduce the dose of craniospinal radiation to 1,800 cGy, virtually no attention has been paid to the possible contribution of the chemotherapy to the cognitive decline ... first identifying risk factors for radiation-induced cognitive decline and then modifying treatments to reduce neurotoxicity [7] Two of the most important of the risk factors are high dose and...

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Báo cáo y học: "The anti-inflammatory effects of levocetirizine - are they clinically relevant or just an interesting additional effect" pptx

Ngày tải lên : 08/08/2014, 21:20

... considerable interest in the effect of anti-inflammatory drugs on the pro-inflammatory processes responsible for the manifestations of allergic disease Antiinflammatory effects independent of H1-receptor ... particular effects on quality of life parameters Furthermore, use of rescue therapy (cromolyn and salbutamol) was significantly lower in the levocetirizine group The authors concluded that their findings ... Anti-inflammatory effects - in vivo studies A number of reports suggest that additional antiinflammatory effects may be of relevance to the efficacy of levocetirizine Ciprandi and colleagues [26] compared the...

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Báo cáo khoa học: "The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation" pot

Ngày tải lên : 09/08/2014, 09:20

... reduce the levels of anti-apoptotic Mcl-1 The rather low levels of Bcl-2 in the PC3 cells may explain why the radiation-induced down-modulation of Bcl-2 was of minor importance for the response of ... indicate whether the therapy effects observed are due to inhibition of proliferation, cell death induction, or both Therefore, in a next step, we examined whether the anti-neoplastic effects of ErPC3 ... cells the down-regulation of the two anti-apoptotic Bcl-2 proteins may contribute to the antineoplastic effects of ErPC3 and radiotherapy In contrast, the radiation-induced down-modulation of the...

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Báo cáo y học: " The anti-inflammatory effects of the tellurium redox modulating compound, AS101, are associated with regulation of NFB signaling pathway and nitric oxide induction in macrophages" doc

Ngày tải lên : 11/08/2014, 08:22

... of the study, performed the experiments and carried out the majority of the assays, performed the statistical analysis, participated in the design and coordination of the study, and drafted the ... grant No 3-2994 from the Chief Scientist Office of the Ministry of Health, Israel This study was a part of the PhD thesis of Miri Brodsky Author details C.A.I.R Institute, The Safdiè AIDS and ... h, the lack of modulation of the NFkB pathway by AS101 at h, concomitantly with the inhibition of iNOS at that time point, prompted us to further explore the mechanism of iNOS inhibition at h The...

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Báo cáo y học: " Study protocol: The development of a pilot study employing a randomised controlled design to investigate the feasibility and effects of a peer support program following discharge from a specialist first-episode " pdf

Ngày tải lên : 11/08/2014, 16:22

... involve the PSW 'weaning' the young person from the support of the PSW by encouraging the young person to be proactive in managing their mental health Unlike the initial phase, most contact in the ... be analysed at the cessation of the study to evaluate the intervention during each of the phases while the qualitative items will be used to direct the intervention throughout the study For example, ... staffed by the PSW supervisor and members of the research and clinical team All PSWs will be required to ensure that the on-call supervisor knows of the time and location of their visit The PSW...

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báo cáo khoa học: " Getting the message straight: effects of a brief hepatitis prevention intervention among injection drug users" pps

Ngày tải lên : 11/08/2014, 18:20

... management, conducted the analyses, and reviewed drafts of the synthesized the analyses RNB, PAM, and MS helped develop the intervention, were responsible for the conduct of this study at their respective ... (22.8% of exposed vs 30% of unexposed; p > 0.05) Finally, we assessed the effectiveness of prevention messages contained in the palm card Several of these messages were consistent with other messages ... beyond the point of distribution and into the larger IDU community Methods We conducted the hepatitis intervention sub-study in Year of the four-year longitudinal study The study design for the...

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Báo cáo y học: "Beat-to-beat changes in stroke volume precede the general circulatory effects of mechanical ventilation: a case report" pps

Ngày tải lên : 12/08/2014, 18:20

... hospital, regard- less of the level of the neonatal intensive care unit, and the circulatory effects of conventional ventilator settings have to be considered As well as the pulmonary effects not discussed ... small and the CO returned to the baseline value Heart rate, blood pressure and oxygen saturation were otherwise recorded independently of the central circulatory effects of ventilation Further course ... ventilation for a further days and supplementary oxygen for a further week The baby was initially tube fed and eventually allowed home at the age of weeks At discharge, computed tomography of the brain...

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Báo cáo khoa học: "Partitioning the work-sparing effects of partial ventilatory support in airflow obstruction" ppsx

Ngày tải lên : 12/08/2014, 20:20

... Moreover, for the same externally measured workload, the efficiency of the muscles in generating pleural pressure varies with the configuration of the chest wall and the extent to which the muscles ... counterproductive, disadvantaging the inspiratory muscles and perhaps reducing the compliance of the respiratory system In the end, we cannot conclude on the basis of this experimental work that ... contribution to the work benefit accruing to positive airway pressure in the setting of airflow obstruction However, although the implications of the study are limited, I commend the authors for...

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Báo cáo y học: " Peripheral muscarinic receptors mediate the anti-inflammatory effects of auricular acupuncture" ppsx

Ngày tải lên : 13/08/2014, 14:20

... focus of the projection bulb was directed to the middle of the plantar surface of the animal with the aid of a mirror attached to the stimulator The intensity of the light source was adjusted to the ... induced by subcutaneous injection of 50 μl of 2% CA lambda (Sigma-Aldrich, USA) in 0.9% saline at the center of the left paw on the planter surface At the end of the experiments, animals were sacrificed ... baseline taken before the induction of anesthesia and CA injection The assessor who took the above measurements was blinded to the group status of the animal Localization of auricular acupoints...

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Actual situation study, some factors has risk to infect larva of toxocara canis in human and effect of treatment by albendazole at 2 commune of an nhon district, binh dinh province (2011 2012)

Ngày tải lên : 29/10/2014, 22:17

... and the prevalence of Toxocara canis larvae in research sites - The relation between playing in the dirt, exposing to soil and the prevalence of Toxocara canis larvae in humans: The risk of the ... and a group of 162 people (20.2%) was over 60 year old It was mainly focused on the group of subjects of 15 – 60 year old (60.0%) The group of to under 15 years old and the group of over 60 year ... cadres, officials with 15/800 people (1.87%); other professions with 17/800 people (2.1%) The difference between different profession groups: Cadres/officials, farmers, pupils and other professions...

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The long term effects of behavioral interventions on condom use and sexually transmitted infections among female brothel based sex workers in singapore, 1994 2002

Ngày tải lên : 17/09/2015, 17:20

... brothels’ or in private homes of their pimps or agents Figure 2 Brothels in Singapore Front of a brothel The interior of a brothel Back alley of a brothel where clients gather A room in the brothel ... sex establishments The authors’ concern then was the sustainability of the high level of condom use as the 100% condom promotion program relied heavily on the cooperation of the police Subsequent ... Teck Ngee for their assistance in the preparation of the colored photos, graphs and some of the video clips ii Heath staff from the Department of STI control, especially Mrs Chew, Theresa, Mr Soh,...

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