... use random simulation In each simulation, the binding sites are shuffled at random while keeping the number of sites within each promoter region the same as inthe true data That is, the binding ... http://genomebiology.com/2005/6/12/R103 lobs be the linear line that best fits the points (in the sense that it minimizes the sum of squares of the distances) The sign of the slope of lobs defines the correlation as positive ... specificity on the one hand, and would also allow for the addition of new binding sites on the other In this case, both binding-site fuzziness and combinatorial regulation reflect the same gene...
... improving the quality of life The differences are between perspectives: the individual andthe societal; the negative andthe positive; the curative andthe preventive; the reductivist andthe holistic ... cold weather, exposure to drafts and winds, changes inthe weather, and not being properly clothed in cold weather Shared belief in balance in health and illness: “weak lungs,” overexertion, and ... is The way you the things you Culture — is the sum total of the way of living; including values, beliefs, aesthetic standards, linguistic expression, patterns of thinking, behavioral norms, and...
... in flows of foreign direct investment (Kuo and Li, 2003) SMEs also serve as the key engine behind equalizing income disparity among workers SMEs are increasingly internationalizing their business ... cost in developing new products in SMEs To understand the importance of coordinating these sections with the project manager and validated the model, the author interviewed 20 project managers The ... According to these definitions andthe importance of SMEs in manufacturing industries in this research, the author chose these types of companies Strengths and weakness characteristics of SMEs in...
... factor; p/CIP: p300/CBP interacting protein; PRMT: Protein arginine methyltransferase; RBP-2: retinol-binding protein 2; RIZ1: retinoblastoma protein-interacting zinc-finger 1; SAS2: serum antigenic ... and 5-Aza-CdR are currently FDA-approved and used in cancer therapies The major hindrance of their usage in humans is their instability in vivo andthe toxicity secondary to their excessive incorporation ... andinthe beginning of the leader region of HIV1 The U3, R, U5 and leader regions are indicated Nucleotide (nt1) is the start of U3 inthe 5'LTR The transcription start site corresponds to the...
... (xi ) ≤ τ (xb ) If xk ≤ m then τ contains σ, and if x1 > m then τ contains σ If neither of these, then the x1 ≤ m so that τ (x1 ) ≤ m, hence τ (xa ) ≤ τ (x1 ) ≤ m and therefore xa ≤ m; similarly ... (xk ) > m, hence τ (xb ) ≥ τ (xk ) > m and therefore xb > m, contradicting b < a.] Recalling that k precedes in σ, the identity permutation in Sn avoids σ and demonstrates that F (n, σ) ≥ for every ... give, as Theorem 1, a simple argument, involving subadditivity, which shows that the two versions of the conjecture are equivalent Here is some background information on the current status of the...
... b + 2, , n} obtained by replacing the point (j, c) with (j, b − ǫ) and (b + ǫ, c) andthe point (ℓ, a) with (b − ǫ, a) and (ℓ, b + ǫ) on the permutation diagram of π In other words, let π = ... Figure 1: An injection f : Sn (321; 1) → Sn+2 (321) The “3” and “1” inthe unique occurrence of 321 are each replaced by two new points (in blue) The proofs in [3, 4] enumerated a more ... give the distribution for the statistic of the number of fixed points on Sn (321; 1), since the map f preserves the number of fixed points References [1] D E Knuth The Art of Computer Programming,...
... perspective, the hazard ratios for PFS obtained inthe current analysis compare well with those obtained in other studies that have investigated the addition of another drug inthe taxane-based chemotherapy ... the combination of clinical and molecular factors will guide the clinician in identifying the most effective therapy for a given patient, leaving more space and giving more importance to the molecular ... to the events of severe toxicities that are observed in studies that explore the benefits determined by the polychemotherapy compared to single drug therapy, are well comparable with the increase...
... effective based upon the patient remaining on therapy and achieving either low disease activity (DAS28 1.2 unit improvement in their DAS28 The PPV of the administrative data-based ... written informed consent VARA contains demographic, clinical and RA-specific information including disease activity scores (DAS), as assessed by physicians using the DAS28 [23] andthe Clinical ... inthe months prior to the index date), increase in glucocorticoid dose at months 6-12 (for those who received any oral glucocorticoids prescriptions inthe months prior to the index date), and...
... 4-20) Nine patients had their tumors within the head, inthe body andinthe tail of the pancreas Notably one patient was demonstrated to have liver metastasis The predominant presenting complaint ... abdominal pain (8/18) The rest of the patients were asymptomatic and tumors were detected incidentally during routine physical examination All these patients had no other obvious symptoms including ... or tail of the pancreas For tumors of SPT located inthe neck and body of the pancreas, resection of the midportion of the pancreas andthe mass with preserving the rim of the head and tail portion...
... inch is made in 121 the skin at the entry site A guide wire is inserted down to the facet joint and then secured into the joint surface A dilation system is inserted over the guide wire and used ... within the joint, dorsal root axons should be incapable of re-innervating the joint In this study we investigate the long-term efficacy of facet debridement for the treatment of chronic back pain ... facet joint pain to return following dorsal root rhizotomy We speculate that the direct visualization of the joint allows better de-innervation of the joint and removal of the entire end-plate receptors...
... substituted The patient was sedated but alert Remifentanil and midazolam were the most commonly used sedating agents Utilizing fluoroscopy, the entry site was then determined and a 3/4-inch incision ... baseline in Oswestry Disability Index (Oswestry) and Visual Analog Scale (VAS) pain scores Scores were assessed at baseline and again at follow-up Results The author acknowledges that there are ... proximity to the major abdominal and thoracic organs and neurovasculature [4], and posterior approaches require subperiosteal of the paraspinal muscles, which can result in increased pain and spasms...
... hSGLT1, suggesting that differences inthe aglycon binding site play an important role inthe inhibitory effect of this substance In contrast, differences inthe sugar binding site resulted in an preferen- ... demonstrated in vitro [19, 20] andin vivo animal models [17, 21-26] Among these, thioglycosides are important to consider because they are not hydrolysed by β-glucosidases inthe intestine and can ... been previously described [31-33] For the purpose of the present study the thioglycosides used were selected and grouped based on their differences inthe aglycone binding site or inthe glucose...
... scores in all patients with and without relevant coronary stenosis The boundaries of the box are Tukey’s hinges The median is identified by the line inside the box The length of the box is the interquartile ... according to whether the patients had prior revascularization The boundaries of the box are Tukey’s hinges The median is identified by the line inside the box The length of the box is the interquartile ... non-invasive or invasive diagnostic and monitoring methods In conclusion, the multi-functional mathematical systems analysis of the resting ECG inthe frequency and time domains done using the...
... stores are now in Thailand, Malaysia, Singapore, Hong Kong, Mainland China, South Korea, the Philippines; Macro is in Thailand and Taiwan, Carrefour from France is in Taiwan; and Wellcome is in Taiwan, ... despite the low income per capita, department store and other modern retailing outlets are mushrooming all over the country’s main cities at an unprecedented growth rate Andin Indonesia, the changing ... materials are rarely seen, though they are becoming more prevalent Street-front shops are located around city centers and along main roads They are similar to shop houses found in other areas in Southeast...
... activities are increasingly expanding, attracting many banks, individuals and households Inthe near future, these activities will certainly grow more, not only banks but also other financial institutions ... Business English 50B INTRODUCTION Introduction of the research topic and rationale Nowadays, banking is one of the most important financial channel for the economy Improving and expanding banking ... the branch: expanding, strengthening and improving the operational efficiency of the office agency To attract more customers, the branch concentrates to the expansion of lending methods in line...
... mutagens We recommend the Ames test using these sensitive strains (especially YG1041 and/ or YG1042) in combination with the standard tester strains (TA98 and TA100 series), in order to detect the mutagenicity ... 2-Nitrofluoranthene, 1-nitropyrene and 1,8-dinitropyrene are tested without S9mix, Glu-P-1 and Trp-P-2 are tested with S9mix using TA98 and YG1041 2-Nitronaphthalene, 2,4-dinitrotoluen and 4-nitroquinoline ... C8-modified deoxyinosine and N2- and C8-modified deoxyguanosine as major products of thein vivo reaction of N-hydroxy-6-aminochrysene with DNA andthe formation of the adducts in isolated rat...
... obtained from oxygen through the ozone generator (OZONIA, USA) and was continuously diffused at a flow rate of 0.5 L/min into the photo reactor Inthe 0.5 L reactor, ozone was directly injected into ... that both the ozone andthe UV were strong disinfectants, andthe OH° formed by ozone/UV process could inactivate E coli present in sewage effluent This indicates that the ozone alone andthe UV ... constantly until the run was finished Inthe ozone/UV process, TOC value was steadily decreased by 90% duringthe run time, showing prominent effectiveness for the mineralization of organics The oxidative...
... Ag-protein stain, the components varied greatly by polymer Several bands demonstrated the same mobility in both stains, suggesting that these bands were complexes of protein and saccharide These included ... included the band corresponding to a molecular weight of 103,000 inthe steaming-extracted polymer (1), the band corresponding to 38,000 inthe NaOH-extracted polymer (2), the band corresponding to ... determined using the molybdenum-H2SO4 method (Schnittger et al., 1959) Protein was determined according to the method of Lowry et al (1951) using a bovine serum albumin standard Nucleic acid and...
... educational intervention The local people were using pit latrines and hand pumps which were installed at the beginning of the establishment of Bauniabad area The main activities included; (i) a baseline ... However, they have gradually increased the proportion of the installation cost share This is because the people were involved from the beginning of the installation and they understood the benefit ... connecting households • To operate and maintain the biogas plant system continuously, it is necessary to establish the operation and maintenance system including the maintenance cost sharing by the...